Aegithus clavicornis (Linnaeus) (Coleoptera: Erotylidae) in the Dominican Republic

Establishment of fungus beetles (Coleoptera: Erotylidae) in new isolated countries is rare. We report Aegithus clavicornis (Linnaeus) for the first time from the Dominican Republic, representing the first true record for this genus from the Greater Antilles

Dynamics of dark energy with a coupling to dark matter

Dark energy and dark matter are the dominant sources in the evolution of the late universe. They are currently only indirectly detected via their gravitational effects, and there could be a coupling between them without violating observational constraints. We investigate the background dynamics when dark energy is modelled as exponential quintessence, and is coupled to dark matter via simple models of energy exchange. We introduce a new form of dark sector coupling, which leads to a more complicated dynamical phase space and has a better physical motivation than previous mathematically similar couplings.Comment: 11 pages, 4 figures, revtex, references adde

Quintessence with quadratic coupling to dark matter

We introduce a new form of coupling between dark energy and dark matter that is quadratic in their energy densities. Then we investigate the background dynamics when dark energy is in the form of exponential quintessence. The three types of quadratic coupling all admit late-time accelerating critical points, but these are not scaling solutions. We also show that two types of coupling allow for a suitable matter era at early times and acceleration at late times, while the third type of coupling does not admit a suitable matter era.Comment: 11 pages, 8 figures, revte

Attractiveness of Gel, Granular, Paste, and Solid Formulations of Ant Bait Insecticides to the Little Fire Ant, Wasmannia auropunctata (Roger) (Hymenoptera: Formicidae)

The little fire ant, Wasmannia auropunctata (Roger) (Hymenoptera: Formicidae), was first detected in plant nurseries in the Puna district of Hawaii island in 1999. W. auropunctata has since spread throughout Hawaii island, and is reported in homes, landscapes, plant nurseries and orchards, and forested areas. This study evaluated: 1) the attractiveness of several granular, liquid, gel, and paste insecticidal ant baits for homeowner and commercial use as compared with the standard granular baits containing hydramethylnon known to be attractive to and effective against W. auropunctata, and 2) the effects of weathering on granular bait attractiveness. Field attractiveness choice tests were conducted in an infested 37.2-m2 plot, and worker ant foraging and recruitment were recorded at 15-min intervals for 2 h. Granular and paste products that were as attractive as standard granular baits (Amdro Fire Ant Bait, Probait) included others formulated with hydramethylnon, abamectin, hydramethylnon and S-methoprene, indoxacarb, fipronil, and metaflumizone. None of the gel or liquid ant bait products evaluated (active ingredients hydramethylnon, sodium tetraborate pentahydrate, thiameth- oxam, fipronil or indoxacarb) were attractive to foraging workers. Attraction of these baits could possibly be improved with inclusion of preferred food sources, such as peanut butter or animal-based protein. Attractiveness of granular ant baits exposed to 7 and 14 days of weathering fell by 40 to 96% as compared to fresh deposits. Corn grit baits should be formulated to preserve attractiveness in tropical environments with high rainfall

Finanzas personales de los estudiantes de la Facultad de Ciencias Contables, Administrativas y Económicas de la Universidad Nacional de Pilar

The research analyze the knowledge regarding personal finance and how students of the Faculty of Accounting, Administrative and Economic Sciences of the National University of Pilar apply it to their daily lives, in the period 2021. They are approached from three margins: identify the financial knowledge that students have, describe the management of a personal financial planning of students, the importance they give and the application to daily life. The research assumes a descriptive level methodology, non-experimental design - transversal, with a quantitative approach. As a method of data collection, the survey and the interview are used. The population is made up of students from 2nd to 5th grade. The sample is represented by 57 students. The results show that only 43% of the students plan their finances, the rest give little importance to the facilities provided by the financial system, so they incipiently apply personal financial planning to their daily lives, however, they do not have difficulties. to sustain reasonable economic stability, although it does make it difficult for them to develop a saving culture.La investigación analiza los conocimientos referentes a las finanzas personales y cómo lo aplican a su vida cotidiana los estudiantes de la Facultad de Ciencias Contables, Administrativas y Económicas de la Universidad Nacional de Pilar, en el periodo 2021. Se aborda desde tres márgenes: identificar los conocimientos financieros que poseen los estudiantes, describir el manejo de una planificación financiera personal de los estudiantes, e importancia que otorgan y la aplicación a la vida cotidiana. La investigación asume una metodología de nivel descriptivo, de diseño no experimental – trasversal, con un enfoque cuantitativo. Como método de recolección de datos se utiliza la encuesta. La población está conformada por estudiantes del 2º al 5º curso. La muestra está representada por 57 estudiantes. Los resultados arrojan que solo el 43 % de los estudiantes planifican sus finanzas, el resto le otorgan poca importancia a las facilidades que otorga el sistema financiero, por lo que incipientemente aplican una planificación financiera personal a su vida cotidiana, no obstante, no poseen dificultades para sostener una estabilidad económica razonable, aunque si les dificulta desarrollar la cultura del ahorro

Erros em prescrições de antimicrobianos em estabelecimentos de saúde: uma revisão sistemática / Errors in antimicrobial prescrip-tions in health establishments: a systematic review

OBJETIVO: Sintetizar através de uma revisão sistemática, as informações disponíveis na literatura sobre variáveis relacionadas aos erros de prescrições de medicamentos antimicrobianos. MÉTODOS: Realizou-se um estudo de revisão sistemática do tipo descritivo e comparativo, organizado de acordo com os critérios preferred reporting items for systematic reviews and meta-analyses (Prisma). Como critério de inclusão foram considerados artigos publicados no período de 2011 à 2021, sendo aceitos trabalhos em português, inglês e espanhol, de forma a abranger literaturas atuais de acordo com a legislação farmacêutica vigente. RESULTADOS: Obteu-se 636 artigos, sendo 155 oriundos da Biblioteca Nacional em Saúde (BVS) e 481 do PubMed. A partir da seleção dos estudos relevantes para o desenvolvimento desta revisão, selecionou-se 20 artigos que se enquadravam dentro dos critérios de exclusão e inclusão estabelecidos no protocolo. CONCLUSÕES: Através deste trabalho, foi possivel observar a importância do farmacêutico na dispensação e controle de medicamentos antimicrobianos, através de ações como uma análise adequada da prescrição, verificando a conformidade desta dentro dos padrões exigidos pela legislação vigente, contribuindo assim, para o uso racional de medicamentos, evitando o aumento da resistência bacteriana, ocasionada pelo uso inadequado e descontrolado de antimicrobianos

Hipertensão Arterial Sistêmica em Trabalhadores / Worker’s Systemic Arterial Hypertension

Introdução - A hipertensão arterial sistêmica vem apresentando associação com o exercício laboral dos trabalhadores.  Objetivo - Análise da prevalência de hipertensão arterial sistêmica e dos seus fatores associados em trabalhadores da indústria da Região Metropolitana de Recife – PE. Estudo transversal de base populacional com 727 trabalhadores. Métodos - A coleta de dados foi realizada através de questionário padronizado. A análise da prevalência de Hipertensão Arterial Sistêmica com os fatores associados simples e ajustada foi feita através da regressão de Poisson para as características socioeconômicas/ocupacionais (escolaridade, função desempenhada, tempo na indústria e turno de trabalho), comportamentais (sal de adição, consumo de álcool, tabagismo e prática de atividade física), demográficas/saúde (sexo, idade, índice de massa corpórea e circunferência da cintura). Resultados - A prevalência de hipertensão foi de 36,6%. Os fatores que apresentaram associação independente com a Hipertensão Arterial Sistêmica foram: socioeconômicos/ocupacionais, trabalhar na Diretoria/Gerência/Coordenação de produção e técnicos (RP=1,62, p=0,005), Produção (RP=1,50, p=0,011), ter um vínculo de 2-9 anos (RP=1,32, p=0,046) ou maior ou igual a 10 anos (RP=1,72, p<0,001); fatores comportamentais como, não adicionar sal às refeições (RP=1,50, p=0,001), ter um consumo moderado (RP=1,31, p=0,008) e excessivo (RP=1,49, p=0,012) de álcool;  os fatores demográficos/saúde, sexo masculino (RP=1,32, p=0,041), ter 40-49 anos (RP=1,72, p=0,001) ou maior ou igual a 50 anos (RP=2,43, p<0,001) e ser sobrepeso (RP=1,63, p=0,001) ou obeso (RP=2,48, p<0,001). Conclusão - A análise permitiu identificar diversos fatores entre as variáveis socioeconômicas/ocupacionais, comportamentais e demográficas/saúde independentemente associados com a hipertensã

Cannabinoid receptors in GtoPdb v.2023.1

Cannabinoid receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Cannabinoid Receptors [119]) are activated by endogenous ligands that include N-arachidonoylethanolamine (anandamide), N-homo-γ-linolenoylethanolamine, N-docosatetra-7,10,13,16-enoylethanolamine and 2-arachidonoylglycerol. Potency determinations of endogenous agonists at these receptors are complicated by the possibility of differential susceptibility of endogenous ligands to enzymatic conversion [5].There are currently three licenced cannabinoid medicines each of which contains a compound that can activate CB1 and CB2 receptors [111]. Two of these medicines were developed to suppress nausea and vomiting produced by chemotherapy. These are nabilone (Cesamet®), a synthetic CB1/CB2 receptor agonist, and synthetic Δ9-tetrahydrocannabinol (Marinol®; dronabinol), which can also be used as an appetite stimulant. The third medicine, Sativex®, contains mainly Δ9-tetrahydrocannabinol and cannabidiol, both extracted from cannabis, and is used to treat multiple sclerosis and cancer pain

Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry.

Importance:Primary open-angle glaucoma presents with increased prevalence and a higher degree of clinical severity in populations of African ancestry compared with European or Asian ancestry. Despite this, individuals of African ancestry remain understudied in genomic research for blinding disorders. Objectives:To perform a genome-wide association study (GWAS) of African ancestry populations and evaluate potential mechanisms of pathogenesis for loci associated with primary open-angle glaucoma. Design, Settings, and Participants:A 2-stage GWAS with a discovery data set of 2320 individuals with primary open-angle glaucoma and 2121 control individuals without primary open-angle glaucoma. The validation stage included an additional 6937 affected individuals and 14 917 unaffected individuals using multicenter clinic- and population-based participant recruitment approaches. Study participants were recruited from Ghana, Nigeria, South Africa, the United States, Tanzania, Britain, Cameroon, Saudi Arabia, Brazil, the Democratic Republic of the Congo, Morocco, Peru, and Mali from 2003 to 2018. Individuals with primary open-angle glaucoma had open iridocorneal angles and displayed glaucomatous optic neuropathy with visual field defects. Elevated intraocular pressure was not included in the case definition. Control individuals had no elevated intraocular pressure and no signs of glaucoma. Exposures:Genetic variants associated with primary open-angle glaucoma. Main Outcomes and Measures:Presence of primary open-angle glaucoma. Genome-wide significance was defined as P < 5 × 10-8 in the discovery stage and in the meta-analysis of combined discovery and validation data. Results:A total of 2320 individuals with primary open-angle glaucoma (mean [interquartile range] age, 64.6 [56-74] years; 1055 [45.5%] women) and 2121 individuals without primary open-angle glaucoma (mean [interquartile range] age, 63.4 [55-71] years; 1025 [48.3%] women) were included in the discovery GWAS. The GWAS discovery meta-analysis demonstrated association of variants at amyloid-β A4 precursor protein-binding family B member 2 (APBB2; chromosome 4, rs59892895T>C) with primary open-angle glaucoma (odds ratio [OR], 1.32 [95% CI, 1.20-1.46]; P = 2 × 10-8). The association was validated in an analysis of an additional 6937 affected individuals and 14 917 unaffected individuals (OR, 1.15 [95% CI, 1.09-1.21]; P < .001). Each copy of the rs59892895*C risk allele was associated with increased risk of primary open-angle glaucoma when all data were included in a meta-analysis (OR, 1.19 [95% CI, 1.14-1.25]; P = 4 × 10-13). The rs59892895*C risk allele was present at appreciable frequency only in African ancestry populations. In contrast, the rs59892895*C risk allele had a frequency of less than 0.1% in individuals of European or Asian ancestry. Conclusions and Relevance:In this genome-wide association study, variants at the APBB2 locus demonstrated differential association with primary open-angle glaucoma by ancestry. If validated in additional populations this finding may have implications for risk assessment and therapeutic strategies

Characteristics and Outcomes of Adults Hospitalized with SARS-CoV-2 Community-Acquired Pneumonia in Louisville, Kentucky

Background: Patients infected with the novel coronavirus SARS-CoV-2 are frequently hospitalized with community-acquired pneumonia (CAP). The objective of this study was to define the clinical characteristics and outcomes of hospitalized patients with SARS-CoV-2 CAP in the city of Louisville, KY. Methods: This was a retrospective observational study of 700 patients with SARS-CoV-2 infection hospitalized to eight of the adult hospitals in the city of Louisville. Patients with 1) a positive RT-PCR for SARS-CoV-2, 2) fever, cough, or shortness of breath, and 3) an infiltrate at chest imaging were defined as having SARS-CoV-2 CAP. Demographic characteristics of the study population were compared with census data from the city of Louisville. For each patient more than 500 variables were abstracted from electronic medical records and recorded using Research Electronic Data Capture software. Data was analyzed by descriptive and inferential statistics using R version 3.4.0. Results: SARS-CoV-2 CAP was identified in 632 (90%) patients hospitalized with COVID-19. The median age of the patients was 63 years, 53% were females, 31% were black and 12% Hispanic. The most frequent comorbidities were hypertension (56%), obesity (50%), and diabetes (33%). Mortality was 17% for the total population and 34% for the 249 patients admitted to ICU. For each category of race, ethnicity and comorbidities, the proportion of hospitalized patients with SARS-CoV-2 CAP was significantly different when compared to the Louisville population (p \u3c 0.001). Conclusion: Patients of black race, Hispanic ethnicity, and patients with history of hypertension, obesity or diabetes are overrepresented among hospitalized patients with SARS-CoV-2 CAP when compared to the Louisville population. Hospitalized patients with SARS-CoV-2 CAP are likely to require ICU care, with death occurring in approximately one of six hospitalizations