95 research outputs found
Bracketing in Phenomenology: Only Undertaken in the Data Collection and Analysis Process
Our aim with this article is to demonstrate how the researchers use bracketing as a method of demonstrating the validity after initiating a phenomenological study. Although bracketing is a method of demonstrating the validity of the da ta collection and analysis process in most phenomenological studies, how the researchers use them in practice is rarely demonstrated explicitly. We collected data through our experiences in preparing a phenomenological research study. We suggest that the concept of bracketing should be adopted upon initiating the research proposal and not merely in the data collection and analysis process. We propose four strategies for doing bracketing that are guided by the thinking activity of reflexivity: mentality assessment and preparation before deciding the research paradigm, deciding the scope of the literature review according to the prevailing gate - keeping policy, planning for data collection using semi - structured interviews guided by open - ended questions, and planning for data analysis using Colaizzi’s method. Our proposition highlights that thorough preparation for doing bracketing is essential before entering the data collection and analysis process in phenomenology, because they are sequentially related
Translation and Validation of the Chinese ICD-11 International Trauma Questionnaire (ITQ) for the Assessment of Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD)
Background: Two stress-related disorders have been proposed for inclusion in the revised ICD-11: Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD). The International Trauma Questionnaire (ITQ) is a bespoke measure of PTSD and CPTSD and has been widely used in English-speaking countries. Objective: The primary aim of this study was to develop a Chinese version of the ITQ and assess its content, construct, and concurrent validity.
Methods: Six mental health practitioners and experts rated the Chinese translated and back-translated items to assess content validity. A sample of 423 Chinese young adults completed the ITQ, the WHO Adverse Childhood Experiences International Questionnaire, and the Hospital Anxiety and Depression Scale. Among them, 31 participants also completed the English and Chinese versions of the ITQ administered in random order at retest. Four alternative confirmatory factor analysis models were tested using data from participants who reported at least one adverse childhood experience (ACE; N = 314).
Results: The Chinese ITQ received excellent ratings on relevance and appropriateness. Test–retest reliability and semantic equivalence across English and Chinese versions were acceptable. The correlated first-order six-factor model and a second-order two-factor (PTSD and DSO) both provided an acceptable model fit. The six ITQ symptoms clusters were all significantly correlated with anxiety, depression, and the number of ACEs.
Conclusions: The Chinese ITQ generates scores with acceptable psychometric properties and provides evidence for including PTSD and CPTSD as separate diagnoses in ICD-11
Health and social care service utilisation and associated expenditure among community-dwelling older adults with depressive symptoms
AIMS: Late-life depression has substantial impacts on individuals, families and society. Knowledge gaps remain in estimating the economic impacts associated with late-life depression by symptom severity, which has implications for resource prioritisation and research design (such as in modelling). This study examined the incremental health and social care expenditure of depressive symptoms by severity. METHODS: We analysed data collected from 2707 older adults aged 60 years and over in Hong Kong. The Patient Health Questionnaire-9 (PHQ-9) and the Client Service Receipt Inventory were used, respectively, to measure depressive symptoms and service utilisation as a basis for calculating care expenditure. Two-part models were used to estimate the incremental expenditure associated with symptom severity over 1 year. RESULTS: The average PHQ-9 score was 6.3 (standard deviation, s.d. = 4.0). The percentages of respondents with mild, moderate and moderately severe symptoms and non-depressed were 51.8%, 13.5%, 3.7% and 31.0%, respectively. Overall, the moderately severe group generated the largest average incremental expenditure (US3849; 95% CI 2520-5177 or a 176% increase) and the moderate group (US691; 95% CI 444-939), then gradually fell to negative between scores of 12 (US -171; 95% CI - 417 to 76) and soared to positive and rebounded at the score of 23 (US$601; 95% CI -1652 to 2854). CONCLUSIONS: The association between depressive symptoms and care expenditure is stronger among older adults with mild and moderately severe symptoms. Older adults with the same symptom severity have different care utilisation and expenditure patterns. Non-psychiatric healthcare is the major cost element. These findings inform ways to optimise policy efforts to improve the financial sustainability of health and long-term care systems, including the involvement of primary care physicians and other geriatric healthcare providers in preventing and treating depression among older adults and related budgeting and accounting issues across services
Sex-specific comparative outcomes between oral anticoagulants in patients with atrial fibrillation: a systematic review and meta-analysis
AIMS: Women with atrial fibrillation (AF) are under-represented in randomised controlled trials (RCTs) of direct oral anticoagulants (DOACs). This systematic review and meta-analysis of RCTs and observational studies examined sex-specific outcomes of DOACs in AF. METHODS: PubMed, Embase, Web of Science and Cochrane Library were searched from January 2008 to November 2022. Sex-specific comparative outcomes of stroke/systemic embolism (SE), major bleeding, intracranial haemorrhage (ICH) and gastrointestinal bleeding (GIB) between oral anticoagulants were pooled using random effects models. P values for interaction were calculated to examine differences in results between sexes. RCTs and observational studies were meta-analysed separately. RESULTS: 5 RCTs and 33 observational studies were included, totalling 1 085 931 women and 1 387 123 men. Meta-analyses showed that for both sexes, DOAC versus warfarin was generally associated with lower risk of stroke/SE, major bleeding and ICH; in DOAC-DOAC comparisons, rivaroxaban versus dabigatran had higher GIB risk. The only sex-specific difference observed was that when compared with warfarin, women had higher GIB risk with rivaroxaban (women: pooled risk ratio (pRR)=1.34, 95% CI=1.18 to 1.51; men: pRR=0.97, 95% CI=0.85 to 1.10; p value for interaction (p for interaction)<0.001) and possibly dabigatran (women: pRR=1.25, 95% CI=0.92 to 1.70; men: pRR=0.83, 95% CI=0.72 to 0.97; p-for-interaction=0.02). The sex difference in GIB remained for rivaroxaban when a Bonferroni-corrected significance level was used (α=0.003). No sex-specific GIB data for apixaban and edoxaban was available for the meta-analysis. CONCLUSIONS: For both sexes, DOACs generally demonstrated favourable effectiveness and safety over warfarin. However, observational data suggested that women may have higher GIB risk with rivaroxaban and possibly dabigatran than warfarin. Further studies are warranted to verify our findings and elucidate sex-specific GIB risk with apixaban and edoxaban, of which the data is currently lacking. PROSPERO REGISTRATION NUMBER: CRD42022325027
Treatment Outcomes of Patients With Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis According to Drug Susceptibility Testing to First- and Second-line Drugs: An Individual Patient Data Meta-analysis
The clinical validity of drug susceptibility testing (DST) for pyrazinamide, ethambutol, and second-line antituberculosis drugs is uncertain. In an individual patient data meta-analysis of 8955 patients with confirmed multidrug-resistant tuberculosis, DST results for these drugs were associated with treatment outcome
IEEE Journal of Lightwave Technology - May-June - Vol. 31, No. 9-12
1. On Wavelength-Routed Networks with Reversible Wavelength Channels/ C.Y. Li, P.K.A. Wai, V.O.K. Li
2. A New Method for Maximum Likelihood Parameter Estimation of Gamma-Gamma Distribution/ M. Kazeminia, M. Mehrjoo
3. Study of 100 Gigabit Ethernet Using Carrierless Amplitude/Phase Modulation and Optical OFDM/ J.L. Wei, et al.
4. Sequential Optimization of Adaptive Arrays in Coherent Laser Communications/ A. Belmonte, J.M. Kahn
5. Novel High-Speed Polarization Source Decoy-State BB84 Quantum Key Distribution Over Free Space and Satellite LInks/ Z. Yan, et al.
6. Optimal Scattering Induced Noise in Fiber Ring Resonators and Optoelectronic Oscillators/ K. Saleh, O. Llopis, G. Cibiel
7. Enhancing the Sensitivity of Interferometer Based In-Band OSNR Monitoring by Narrow Band Filtering/ A. Annoni, F. Morichetti
8. Performance Evaluation of DEDM Communication System with Fiber Optical Parametric Amplifiers/ M. Jazayerifar, et al.
9. Dynamic Control of Phase Matching in Four-Wave Mixing Wavelength Conversion of Amplitude- and Phase- Modulated/ L. Wang, C. Shu
10. Polarization in Phase Modulated Optical Links: Jones- and Generalized Stokes-Space Analysis/ N.J. Frigo, F. Bucholtz, C.V. McLaughli
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