721 research outputs found

    Antiferromagnetism in four dimensions: search for non-triviality

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    We present antiferromagnetism as a mechanism capable of modifying substantially the phase diagram and the critical behaviour of statistical mechanical models. This is particularly relevant in four dimensions, due to the connection between second order transition points and the continuum limit as a quantum field theory. We study three models with an antiferromagnetic interaction: the Ising and the O(4) Models with a second neighbour negative coupling, and the \RP{2} Model. Different conclusions are obtained depending on the model.Comment: 4 pages LateX. Contribution to Lat9

    Phase diagram of d=4 Ising Model with two couplings

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    We study the phase diagram of the four dimensional Ising model with first and second neighbour couplings, specially in the antiferromagnetic region, by using Mean Field and Monte Carlo methods. From the later, all the transition lines seem to be first order except that between ferromagnetic and disordered phases in a region including the first-neighbour Ising transition point.Comment: Latex file and 4 figures (epsfig required). It replaces the preprint entitled "Non-classical exponents in the d=4 Ising Model with two couplings". New analysis with more statistical data is performed. Final version to appear in Phys. Lett.

    Local power and land use: spatial implications for local energy development

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    Background The decentralised and private nature of small-scale renewable energy development does not fit traditional models of government planning and oversight. The land use impacts related to these developments are not well understood and data is lacking related to the environmental, social and economic impacts that can occur under various scenarios. Methods This research note provides a literature review of the scarce information available about the spatial impacts of small-scale renewable energy and outlines the current stream of research being undertaken to address this knowledge gap. The preliminary case studies in Overijssel, the Netherlands and Navarre, Spain provide the background for understanding this complex issue, and a new integrated policy and land use model is introduced in order to combine qualitative and qualitative data that is important for understanding the dynamics of this growing field. Results The main difficulties in moving forward in planning for the decentralised renewable energytransition are the variation of perspectives on the attractiveness and appropriateness of urban renewableenergy (RE) development, differences in implementation processes and incentives, the dynamic nature ofthe relevant technologies and the lack of up to date information on land use. Conclusions Multi-functional land use is a key strategy for increasing the uptake of small-scale renewable energy but little to no data is available regarding it in European land use literature and policy. This needs to be addressed in order to enable pragmatic policies that will enable effective implementation of renewable energ

    Single-shot d-scan technique for ultrashort laser pulse characterization using transverse second-harmonic generation in random nonlinear crystals

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    We demonstrate a novel dispersion-scan (d-scan) scheme for single-shot temporal characterization of ultrashort laser pulses. The novelty of this method relies on the use of a highly dispersive crystal featuring antiparallel nonlinear domains with a random distribution and size. This crystal, capable of generating a transverse second-harmonic signal, acts simultaneously as the dispersive element and the nonlinear medium of the d-scan device. The resulting in-line architecture makes the technique very simple and robust, allowing the acquisition of single-shot d-scan traces in real time. The retrieved pulses are in very good agreement with independent frequency-resolved optical grating measurements. We also apply the new single-shot d-scan to a terawatt-class laser equipped with a programmable pulse shaper, obtaining an excellent agreement between the applied and the d-scan retrieved dispersions

    A versatile cancer cell trapping and 1D migration assay in a microfluidic device

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    Highly migratory cancer cells often lead to metastasis and recurrence and are responsible for the high mortality rates in many cancers despite aggressive treatment. Recently, the migratory behavior of patient-derived glioblastoma multiforme cells on microtracks has shown potential in predicting the likelihood of recurrence, while at the same time, antimetastasis drugs have been developed which require simple yet relevant high-throughput screening systems. However, robust in vitro platforms which can reliably seed single cells and measure their migration while mimicking the physiological tumor microenvironment have not been demonstrated. In this study, we demonstrate a microfluidic device which hydrodynamically seeds single cancer cells onto stamped or femtosecond laser ablated polystyrene microtracks, promoting 1D migratory behavior due to the cells' tendency to follow topographical cues. Using time-lapse microscopy, we found that single U87 glioblastoma multiforme cells migrated more slowly on laser ablated microtracks compared to stamped microtracks of equal width and spacing (p < 0.05) and exhibited greater directional persistence on both 1D patterns compared to flat polystyrene (p < 0.05). Single-cell morphologies also differed significantly between flat and 1D patterns, with cells on 1D substrates exhibiting higher aspect ratios and less circularity (p < 0.05). This microfluidic platform could lead to automated quantification of single-cell migratory behavior due to the high predictability of hydrodynamic seeding and guided 1D migration, an important step to realizing the potential of microfluidic migration assays for drug screening and individualized medicine. Published under license by AIP Publishing
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