814 research outputs found
F-15 composite engine access door
This paper presents a summary of the successfully concluded phase 1 of the two-phase Design and Manufacture of Advanced Thermoplastic Structures (DMATS) program. It addresses the design, manufacture, and validation testing of a thermoplastic F-15E forward engine access door and includes lessons learned during the concurrent product and process design development phases of the program
Coping Ability of Medical and Nursing Students: A Cause of Concern
Background: Medical students today are subject to a variety of stress; academic, social, emotional or stress in the form of affliction of health during their stay at medical school. The physiological response to these depends on various factors including their inherent coping abilities. This study was designed to examine the coping ability of medical and nursing students at the time of admission to medical school. Materials and Methods: 42 medical and 34 nursing students volunteered for the study. They were administered the BAI questionnaire and classified as good and poor adjusters based on their score. Results: The study revealed an unsatisfactory overall coping ability to be prevalent among medical and nursing students. Conclusion: This study showed that there is a need for orientation and counselling of medical and nursing students at the start of college
FAILURE MODES AND EFFECTS ANALYSIS OF DRIVING MECHANISM IN HORIZONTAL PLANNING MACHINE
In this paper the failure analysis and optimization of horizontal mechanism in a horizontal planning machine rack and pinion arrangement is needed for the translation movement. The relative motion between the fixed and movable bed are being in friction with the ability of V guide ways. And the drive of this mechanism is rack and pinion arrangement. In general, wear occurring in V-Guides ways and drive mechanism are not equal. So that, the variation of the wear amount should affect the surface level of to be machined component. The failure is rectified to implement the new mechanism (arrangement) in driven portion of the horizontal mechanism. The main concept of this paper is that the surface level of the machined component has to be fine. The modification of the mechanism is to change the position of gear rack and pinion. In existing, the gear tooth is in horizontal and crosswise to the guide ways. Instead of that, the gear tooth is perpendicular to the guide ways. If the wear occurred in this modified one, the gear engaging length will increase. The modified mechanism does not affect the addendum and dedundum of the gear profile
Cultivating Insight: Detecting Autism Spectrum Disorder through Residual Attention Network in Facial Image Analysis
Revolutionizing Autism Spectrum Disorder Identification through Deep Learning: Unveiling Facial Activation Patterns. In this study, our primary objective is to harness the power of deep learning algorithms for the precise identification of individuals with autism spectrum disorder (ASD) solely from facial image datasets. Our investigation centers around the utilization of face activation patterns, aiming to uncover novel insights into the distinctive facial features of ASD patients. To accomplish this, we meticulously examined facial imaging data from a global and multidisciplinary repository known as the Autism Face Imaging Data Exchange. Autism spectrum disorder is characterized by inherent social deficits and manifests in a spectrum of diverse symptomatic scenarios. Recent data from the Centers for Disease Control (CDC) underscores the significance of this disorder, indicating that approximately 1 in 54 children are impacted by ASD, according to estimations from the CDC's Autism and Developmental Disabilities Monitoring Network (ADDM). Our research delved into the intricate functional connectivity patterns that objectively distinguish ASD participants, focusing on their facial imaging data. Through this investigation, we aimed to uncover the latent facial patterns that play a pivotal role in the classification of ASD cases. Our approach introduces a novel module that enhances the discriminative potential of standard convolutional neural networks (CNNs), such as ResNet-50, thus significantly advancing the state-of-the-art. Our model achieved an impressive accuracy rate of 99% in distinguishing between ASD patients and control subjects within the dataset. Our findings illuminate the specific facial expression domains that contribute most significantly to the differentiation of ASD cases from typically developing individuals, as inferred from our deep learning methodology. To validate our approach, we conducted real-time video testing on diverse children, achieving an outstanding accuracy score of 99.90% and an F1 score of 99.67%. Through this pioneering work, we not only offer a cutting-edge approach to ASD identification but also contribute to the understanding of the underlying facial activation patterns that hold potential for transforming the diagnostic landscape of autism spectrum disorder
Network Management System for (FUTON-like) Radio-over- Fiber Infrastructure
EU-Project FUTON Radio-over-Fiber (RoF) infrastructure proposes high transmission rates at small antenna costs, implying competitive CAPEX for next generation networks. But to be cost-efficient, it needs to employ new network architectures and intelligent technology solutions for decreasing network operational costs. The RoF Network Manager manages the network equipment on the optical front haul between the Central Unit (CU) and all Remote Antenna Units (RAU)s connected by it, as well as the communication links, while enabling end-to-end service problem resolution and service quality management by the FUTON Middleware. Although a significant amount of prior research work can be found in the literature related to RoF, there is still significant lack of technologies concerning RoF networks management. RoF Manager and its sub-systems target to fill such gap, proposing a novel concept in the form of Channel Forwarding Table (CFT). RoF Manager follows an autonomous and generic network management framework, designed to be scalable in terms of adding new network elements (NEs). It targets multitechnology, multi-service and multi-vendor NEs in the network using Simple Network Management Protocol (SNMP). It can also provide alternative paths in case of failure. This work puts forward a new paradigm towards RoF management solution managing network performance, network faults, network security and configurations for convergent networks
Effect of Gymnema montanum Leaves on Serum and Tissue Lipids in Alloxan Diabetic Rats
The effect of Gymnema montanum leaves on alloxaninduced
hyperlipidemia was studied in male Wistar rats.
Ethanolic extract of G. montanum leaves was administered
orally and different doses of the extract on blood glucose,
serum and tissue lipids, hexokinase, glucose-6-phosphatase,
thiobarbituric acidâreactive substances (TBARS), hydroperoxides,
and glutathione in alloxan-induced diabetic
rats were studied. G. montanum leaf extract (GLEt) at doses
of 50, 100, 200 mg/kg body weight for 3 weeks suppressed
the elevated blood glucose and lipid levels in diabetic rats.
GLEt at 200 mg/kg body weight was found to be comparable
to glibenclamide, a reference drug. These data indicate
that G. montanum represents an effective antihyperglycemic
and antihyperlipidemic adjunct for the treatment
of diabetes and a potential source of discovery of new orally
active agent for future therapy
RNAI MEDIATED GENE SILENCING OF EIF3A: A POSSIBLE SOLUTION TO CONTROL BREAST CANCER
Objective: The eukaryotic translational initiation factor 3A (eIF3A) is reported to be over expressed in most breast cancer cells. In the present study, our aim is to suppress the over expression of eIF3A in human breast cancer MCF-7 cell line using gene silencing technique (RNA interference (RNAi)).Methods: The artificial microRNA (amiRNA) targeting eIF3A gene was constructed by incorporating short interference RNA (siRNA) sequences against eIF3A gene into endogenous microRNA30 (miR-30) and cloned into pcDNA3.1 vector. The amiRNA containing plasmid was then transfected into MCF-7 cell line and the expression of eIF3A was examined by RT-PCR. The cytotoxicity of plasmid with amiRNA targeting eIF3A on MCFââŹâ7 cells was evaluated by MTT assay.Results: The amiRNA construct significantly inhibited eIF3A gene expression and reduce the cell viability of MCF-7 cell line.Conclusion: The usage of modified endogenous amiRNA in vector based expression system with significant gene silencing efficiency suggests that RNAi based gene silencing method can be considered as one of the effective means to control cancer.Ă
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