Space shuttle program information control and retrieval system feasibility study report

The feasibility of having a common information management network for space shuttle data, is studied. Identified are the information types required, sources and users of the information, and existing techniques for acquiring, storing and retrieving the data. The study concluded that a decentralized system is feasible, and described a recommended development plan for it

Tidal Flexure of Jakobshavns Glacier, West Greenland

Jakobshavns Glacier, a floating outlet glacier on the West Greenland coast, was surveyed during July 1976. The vertical displacements of targets along two profiles perpendicular to the fjord wall bounding the north margin of the glacier were analyzed to determine the effect of flexure caused by tidal oscillations within the fjord. An analysis based on the assumption that vertical displacements of the glacier reflected pure elastic bending yielded the conclusion that the effective thickness of the ice (i.e., the thickness which remained unaffected by surface and basal cracking and which behaved as a continuum) was ∼160 m 2.6 km upglacier from the calving front and ∼110 m 0.6 km from the calving front. An analysis based on the more realistic assumption that observed bending reflected elastic and viscoplastic deformation yielded the conclusion that the average effective thickness of the ice was 316 ± 74 m (∼40% of the estimated 800-m total thickness) 2.6 km from the calving front and 160 ± 48 m (∼21% of the estimated 750-m total) 0.6 km from the calving front. A constitutive relationship appropriate for hard glide during flexure was used

Satellite Altimetry, Semivariograms, and Seasonal Elevation Changes in the Ablation Zone of West Greenland

Seasonal mean changes in the surface elevation of the ablation zone of West Greenland to 72°N between spring 1985 and summer 1986 are measured using radar altimeter data from the 18-month Geosat Geodetic Mission. Semi-variograms are used to estimate the noise in the data as a function of position on the ice sheet. Mean elevation changes are computed by averaging the elevation differences measured at points where orbits ascending in latitude are later crossed by orbits descending in latitude (or the reverse), with each cross-over difference weighted in proportion to the inverse square of the noise level in the neighborhood of the cross-over point. The mean surface elevation of the ablation zone, relative to spring 1985, ranged from 1.5 ± 0.6 m lower during summer 1985 to 1.7 ± 0.4 m higher during spring 1986

Cash, Crops, Chemicals, and Cosmetics: A Mid-Green Eco-Labeling Approach

The United States Department of Agriculture (USDA) uses grade standards to uniformly characterize the quality and condition of agricultural commodities. The standards are promulgated by the USDA\u27s Agricultural Marketing Services (AMS) division in consultation with farming industry groups. Emphasizing produce attributes such as surface defects, shape, cleanliness, color, maturity, and decay, grade standards improve the marketability of agricultural commodities by establishing a common industry language for use in contracts. Use of such a language enables wholesale buyers to know the quality of commodities without first having to inspect them, thus facilitating trade by lowering transaction costs

Multi-Year Elevation Changes Near the West Margin of the Greenland Ice Sheet from Satellite Radar Altimetry

Mean changes in the surface elevation near the west margin of the Greenland ice sheet are measured using Seasat altimetry and altimetry from the Geosat Exact Repeat Mission (ERM). The Seasat data extend from early July through early October 1978. The ERM data extend from winter 1986-87 through fall 1988. Both seasonal and multi-year changes are measured using altimetry referenced to GEM T2 orbits. The possible effects of orbit error are minimized by adjusting the orbits into a common ocean surface. Seasonal mean changes in the surface height are recognizable during the Geosat ERM. The multi-year measurements indicate the surface was lower by 0.4 +/- 0.4 m on average in late summer 1987 than in late summer 1978. The surface was lower by 0.2 +/- 0.5 m on average in late summer 1988 than in late summer 1978. As a control case, the computations art also carried out using altimetry referenced to orbits not adjusted into a common ocean surface

New insights on commemoration of the dead through mortuary and architectural use of pigments at Neolithic Çatalhöyük, Turkey

The cultural use of pigments in human societies is associated with ritual activities and the creation of social memory. Neolithic Çatalhöyük (Turkey, 7100–5950 cal BC) provides a unique case study for the exploration of links between pigments in burials, demographic data and colourants in contemporary architectural contexts. This study presents the first combined analysis of funerary and architectural evidence of pigment use in Neolithic Anatolia and discusses the possible social processes underlying the observed statistical patterns. Results reveal that pigments were either applied directly to the deceased or included in the grave as a burial association. The most commonly used pigment was red ochre. Cinnabar was mainly applied to males and blue/green pigment was associated with females. A correlation was found between the number of buried individuals and the number of painted layers in the buildings. Mortuary practices seem to have followed specific selection processes independent of sex and age-at-death of the deceased. This study offers new insights about the social factors involved in pigment use in this community, and contributes to the interpretation of funerary practices in Neolithic Anatolia. Specifically, it suggests that visual expression, ritual performance and symbolic associations were elements of shared long-term socio-cultural practices

New insights on commemoration of the dead through mortuary and architectural use of pigments at Neolithic Çatalhöyük, Turkey.

The cultural use of pigments in human societies is associated with ritual activities and the creation of social memory. Neolithic Çatalhöyük (Turkey, 7100-5950 cal BC) provides a unique case study for the exploration of links between pigments in burials, demographic data and colourants in contemporary architectural contexts. This study presents the first combined analysis of funerary and architectural evidence of pigment use in Neolithic Anatolia and discusses the possible social processes underlying the observed statistical patterns. Results reveal that pigments were either applied directly to the deceased or included in the grave as a burial association. The most commonly used pigment was red ochre. Cinnabar was mainly applied to males and blue/green pigment was associated with females. A correlation was found between the number of buried individuals and the number of painted layers in the buildings. Mortuary practices seem to have followed specific selection processes independent of sex and age-at-death of the deceased. This study offers new insights about the social factors involved in pigment use in this community, and contributes to the interpretation of funerary practices in Neolithic Anatolia. Specifically, it suggests that visual expression, ritual performance and symbolic associations were elements of shared long-term socio-cultural practices

Control of Centrin Stability by Aurora A

Aurora A is an oncogenic serine/threonine kinase which can cause cell transformation and centrosome amplification when over-expressed. Human breast tumors show excess Aurora A and phospho-centrin in amplified centrosomes. Here, we show that Aurora A mediates the phosphorylation of and localizes with centrin at the centrosome, with both proteins reaching maximum abundance from prophase through metaphase, followed by their precipitous loss in late stages of mitosis. Over-expression of Aurora A results in excess phospho-centrin and centrosome amplification. In contrast, centrosome amplification is not seen in cells over-expressing Aurora A in the presence of a recombinant centrin mutant lacking the serine phosphorylation site at residue 170. Expression of a kinase dead Aurora A results in a decrease in mitotic index and abrogation of centrin phosphorylation. Finally, a recombinant centrin mutation that mimics centrin phosphorylation increases centrin's stability against APC/C-mediated proteasomal degradation. Taken together, these results suggest that the stability of centrin is regulated in part by Aurora A, and that excess phosphorylated centrin may promote centrosome amplification in cancer

Role of CAP350 in Centriolar Tubule Stability and Centriole Assembly

BACKGROUND: Centrioles are microtubule-based cylindrical structures composed of nine triplet tubules and are required for the formation of the centrosome, flagella and cilia. Despite theirs importance, centriole biogenesis is poorly understood. Centrosome duplication is initiated at the G1/S transition by the sequential recruitment of a set of conserved proteins under the control of the kinase Plk4. Subsequently, the procentriole is assembled by the polymerization of centriolar tubules via an unknown mechanism involving several tubulin paralogs. METHODOLOGY/PRINCIPAL FINDINGS: Here, we developed a cellular assay to study centrosome duplication and procentriole stability based on its sensitivity to the microtubule-depolymerizing drug nocodazole. By using RNA interference experiments, we show that the stability of growing procentrioles is regulated by the microtubule-stabilizing protein CAP350, independently of hSAS-6 and CPAP which initiate procentriole growth. Furthermore, our analysis reveals the critical role of centriolar tubule stability for an efficient procentriole growth. CONCLUSIONS/SIGNIFICANCE: CAP350 belongs to a new class of proteins which associate and stabilize centriolar tubules to control centriole duplication