Information seeking in the Humanities: physicality and digitality

This paper presents a brief overview of a research project that is examining the information seeking practices of humanities scholars. The results of this project are being used to develop digital resources to better support these work activities. Initial findings from a recent set of interviews is offered, revealing the importance of physical artefacts in the humanities scholars’ research processes and the limitations of digital resources. Finally, further work that is soon to be undertaken is summarised, and it is hoped that after participation in this workshop these ideas will be refined

Mental health and emotional well-being of students in further education - a scoping study

This study aimed to explore how FE colleges in England are engaging with and addressing the mental health needs of their young students (aged 16-19), both in terms of promoting positive mental health and emotional well-being and in responding to identified mental health problems

Direct measurements of the polarization of terrestrial kilometric radiation from Voyagers 1 and 2

Terrestrial radiation measurements obtained with planetary radio astronomy experiments on Voyager-1 and 2 during the early portions of each flight show the signals to be predominantly left-hand circularly polarized. Since these emissions were most probably generated above the Northern Hemisphere auroral zone, it is concluded that the radiation is emitted primarily in the extraordinary mode

X-ray Spectroscopy of Candidate Ultracompact X-ray Binaries

We present high-resolution spectroscopy of the neutron star/low-mass X-ray binaries (LMXBs) 4U 1850-087 and 4U 0513-40 as part of our continuing study of known and candidate ultracompact binaries. The LMXB 4U 1850-087 is one of four systems in which we had previously inferred an unusual Ne/O ratio in the absorption along the line of sight, most likely from material local to the binaries. However, our recent Chandra X-ray Observatory LETGS spectrum of 4U 1850-087 finds a Ne/O ratio by number of 0.22+/-0.05, smaller than previously measured and consistent with the expected interstellar value. We propose that variations in the Ne/O ratio due to source variability, as previously observed in these sources, can explain the difference between the low- and high-resolution spectral results for 4U 1850-087. Our XMM-Newton RGS observation of 4U 0513-40 also shows no unusual abundance ratios in the absorption along the line of sight. We also present spectral results from a third candidate ultracompact binary, 4U 1822-000, whose spectrum is well fit by an absorbed power-law + blackbody model with absorption consistent with the expected interstellar value. Finally, we present the non-detection of a fourth candidate ultracompact binary, 4U 1905+000, with an upper limit on the source luminosity of < 1 x 10^{32} erg s^{-1}. Using archival data, we show that the source has entered an extended quiescent state.Comment: 8 pages, 3 figures, accepted for publication to the Astrophysical Journa

Protocol for a randomised control trial of methylnaltrexone for the treatment of opioid-induced constipation and gastrointestinal stasis in intensive care patients (MOTION)

Gastrointestinal dysmotility and constipation are common problems in intensive care patients. The majority of critical care patients are sedated with opioids to facilitate tolerance of endotracheal tubes and mechanical ventilation, which inhibit gastrointestinal motility and lead to adverse outcomes. Methylnaltrexone is a peripheral opioid antagonist that does not cross the blood-brain barrier and can reverse the peripheral side effects of opioids without affecting the desired central properties. This trial will investigate whether methylnaltrexone can reverse opioid-induced constipation and gastrointestinal dysmotility.This is a single-centre, multisite, double-blind, randomised, placebo-controlled trial. 84 patients will be recruited from 4 intensive care units (ICUs) within Imperial College Healthcare NHS Trust. Patients will receive intravenous methylnaltrexone or placebo on a daily basis if they are receiving opioid infusion to facilitate mechanical ventilation and have not opened their bowels for 48 hours. All patients will receive standard laxatives as per the clinical ICU bowel protocol prior to randomisation. The primary outcome of the trial will be time to significant rescue-free laxation following randomisation. Secondary outcomes will include tolerance of enteral feed, gastric residual volumes, incidence of pneumonia, blood stream and Clostridium difficile infection, and any reversal of central opioid effects.The trial protocol, the patient/legal representative information sheets and consent forms have been reviewed and approved by the Harrow Research Ethics Committee (REC Reference 14/LO/2004). An independent Trial Steering Committee and Data Monitoring Committee are in place, with patient representation. On completion, the trial results will be published in peer-reviewed journals and presented at national and international scientific meetings.2014-004687-37; Pre-results

X-Ray Spectroscopy of the Low-Mass X-ray Binaries 2S 0918-549 and 4U1543-624: Evidence for Neon-Rich Degenerate Donors

We present high-resolution spectroscopy of the neutron-star/low-mass X-ray binaries 2S 0918-549 and 4U 1543-624 with the High Energy Transmission Grating Spectrometer onboard the Chandra X-ray Observatory and the Reflection Grating Spectrometer onboard XMM-Newton. Previous low-resolution spectra of both sources showed a broad line-like feature at 0.7 keV that was originally attributed to unresolved line emission. We recently showed that this feature could also be due to excess neutral Ne absorption, and this is confirmed by the new high-resolution Chandra spectra. The Chandra spectra are each well fit by an absorbed power-law + blackbody model with a modified Ne/O number ratio of 0.52+/-0.12 for 2S 0918-549 and 1.5+/-0.3 for 4U 1543-624, compared to the interstellar-medium value of 0.18. The XMM spectrum of 2S 0918-549 is best fit by an absorbed power-law model with a Ne/O number ratio of 0.46+/-0.03, consistent with the Chandra result. On the other hand, the XMM spectrum of 4U 1543-624 is softer and less luminous than the Chandra spectrum and has a best-fit Ne/O number ratio of 0.54+/-0.03. The difference between the measured abundances and the expected interstellar ratio, as well as the variation of the column densities of O and Ne in 4U 1543-624, supports the suggestion that there is absorption local to these binaries. We propose that the variations in the O and Ne column densities of 4U 1543-624 are caused by changes in the ionization structure of the local absorbing material. It is important to understand the effect of ionization on the measured absorption columns before the abundance of the local material can be determined. This work supports our earlier suggestion that 2S 0918-549 and 4U 1543-624 are ultracompact binaries with Ne-rich companions.Comment: 11 pages, 5 figures, major revisions including addition of XMM spectral analysis, accepted for publication in the Astrophysical Journal, vol. 59

Quantum limited particle sensing in optical tweezers

Particle sensing in optical tweezers systems provides information on the position, velocity and force of the specimen particles. The conventional quadrant detection scheme is applied ubiquitously in optical tweezers experiments to quantify these parameters. In this paper we show that quadrant detection is non-optimal for particle sensing in optical tweezers and propose an alternative optimal particle sensing scheme based on spatial homodyne detection. A formalism for particle sensing in terms of transverse spatial modes is developed and numerical simulations of the efficacy of both quadrant and spatial homodyne detection are shown. We demonstrate that an order of magnitude improvement in particle sensing sensitivity can be achieved using spatial homodyne over quadrant detection.Comment: Submitted to Biophys

The falling chain of Hopkins, Tait, Steele and Cayley

A uniform, flexible and frictionless chain falling link by link from a heap by the edge of a table falls with an acceleration $g/3$ if the motion is nonconservative, but $g/2$ if the motion is conservative, $g$ being the acceleration due to gravity. Unable to construct such a falling chain, we use instead higher-dimensional versions of it. A home camcorder is used to measure the fall of a three-dimensional version called an $xyz$-slider. After frictional effects are corrected for, its vertical falling acceleration is found to be $a_x/g = 0.328 \pm 0.004$. This result agrees with the theoretical value of $a_x/g = 1/3$ for an ideal energy-conserving $xyz$-slider.Comment: 17 pages, 5 figure

An examination of the physical and the digital qualities of humanities research

Traditionally humanities scholars have worked in physical environments and with physical artefacts. Libraries are familiar places, built on cultural traditions over thousands of years, and books are comfortable research companions. Digital tools are a more recent addition to the resources available to a researcher. This paper explores both the physical and the digital qualities of modern humanities research, drawing on existing literature and presenting a study of humanities scholars’ perceptions of the research resources they use. We highlight aspects of the physical and digital that can facilitate or hinder the researcher, focusing on three themes that emerge from the data: the working environment; the experience of finding resources; and the experience of working with documents. Rather than aiming to replace physical texts and libraries by digital surrogates, providers need to recognise the complementary roles they play: digital information environments have the potential to provide improved access and analysis features and the facility to exploit the library from any place, while the physical library and resources provide greater authenticity, trustworthiness and the demand to be in a particular place with important material properties