Malformaciones del tracto intestinal

El objetivo general del presente trabajo consiste en demostrar la incidencia de estas malformaciones en fetos que no han llegado a término pertenecientes a la Cátedra de Anatomía “A” de la Facultad de Ciencias Médicas de la Universidad Nacional de La Plata.Facultad de Ciencias Médica

Malformaciones del tracto intestinal

El objetivo general del presente trabajo consiste en demostrar la incidencia de estas malformaciones en fetos que no han llegado a término pertenecientes a la Cátedra de Anatomía “A” de la Facultad de Ciencias Médicas de la Universidad Nacional de La Plata.Facultad de Ciencias Médica

Malformaciones del tracto intestinal

El objetivo general del presente trabajo consiste en demostrar la incidencia de estas malformaciones en fetos que no han llegado a término pertenecientes a la Cátedra de Anatomía “A” de la Facultad de Ciencias Médicas de la Universidad Nacional de La Plata.Facultad de Ciencias Médica

Malformaciones del tracto gastrointestinal

Las malformaciones congénitas del tracto intestinal son relativamente frecuentes, incluyen lesiones de intestino delgado internas y externas, anomalías de colon, defectos de mal rotación, alteraciones anorrectales y duplicaciones intestinales. Constituyen, junto con la prematurez y las enfermedades de causa genética, la principal causa de mortalidad infantil en el primer año de vida y requieren resolución quirúrgica en las primeras horas o días de vida.Facultad de Ciencias Médica

Malformaciones del tracto gastrointestinal

Las malformaciones congénitas del tracto intestinal son relativamente frecuentes, incluyen lesiones de intestino delgado internas y externas, anomalías de colon, defectos de mal rotación, alteraciones anorrectales y duplicaciones intestinales. Constituyen, junto con la prematurez y las enfermedades de causa genética, la principal causa de mortalidad infantil en el primer año de vida y requieren resolución quirúrgica en las primeras horas o días de vida.Facultad de Ciencias Médica

Malformaciones del tracto gastrointestinal

Las malformaciones congénitas del tracto intestinal son relativamente frecuentes, incluyen lesiones de intestino delgado internas y externas, anomalías de colon, defectos de mal rotación, alteraciones anorrectales y duplicaciones intestinales. Constituyen, junto con la prematurez y las enfermedades de causa genética, la principal causa de mortalidad infantil en el primer año de vida y requieren resolución quirúrgica en las primeras horas o días de vida.Facultad de Ciencias Médica

Vaginal neutrophil infiltration is contingent on ovarian cycle phase and independent of pathogen infection

The mucosa of the female reproductive tract must reconcile the presence of commensal microbiota and the transit of exogenous spermatozoa with the elimination of sexually transmitted pathogens. In the vagina, neutrophils are the principal cellular arm of innate immunity and constitute the first line of protection in response to infections or injury. Neutrophils are absent from the vaginal lumen during the ovulatory phase, probably to allow sperm to fertilize; however, the mechanisms that regulate neutrophil influx to the vagina in response to aggressions remain controversial. We have used mouse inseminations and infections of Neisseria gonorrhoeae, Candida albicans, Trichomonas vaginalis, and HSV-2 models. We demonstrate that neutrophil infiltration of the vaginal mucosa is distinctively contingent on the ovarian cycle phase and independent of the sperm and pathogen challenge, probably to prevent sperm from being attacked by neutrophils. Neutrophils extravasation is a multi-step cascade of events, which includes their adhesion through selectins (E, P and L) and integrins of the endothelial cells. We have discovered that cervical endothelial cells expressed selectin-E (SELE, CD62E) to favor neutrophils recruitment and estradiol down-regulated SELE expression during ovulation, which impaired neutrophil transendothelial migration and orchestrated sperm tolerance. Progesterone up-regulated SELE to restore surveillance after ovulation

The Biodiversity of the Mediterranean Sea: Estimates, Patterns, and Threats

The Mediterranean Sea is a marine biodiversity hot spot. Here we combined an extensive literature analysis with expert opinions to update publicly available estimates of major taxa in this marine ecosystem and to revise and update several species lists. We also assessed overall spatial and temporal patterns of species diversity and identified major changes and threats. Our results listed approximately 17,000 marine species occurring in the Mediterranean Sea. However, our estimates of marine diversity are still incomplete as yet—undescribed species will be added in the future. Diversity for microbes is substantially underestimated, and the deep-sea areas and portions of the southern and eastern region are still poorly known. In addition, the invasion of alien species is a crucial factor that will continue to change the biodiversity of the Mediterranean, mainly in its eastern basin that can spread rapidly northwards and westwards due to the warming of the Mediterranean Sea. Spatial patterns showed a general decrease in biodiversity from northwestern to southeastern regions following a gradient of production, with some exceptions and caution due to gaps in our knowledge of the biota along the southern and eastern rims. Biodiversity was also generally higher in coastal areas and continental shelves, and decreases with depth. Temporal trends indicated that overexploitation and habitat loss have been the main human drivers of historical changes in biodiversity. At present, habitat loss and degradation, followed by fishing impacts, pollution, climate change, eutrophication, and the establishment of alien species are the most important threats and affect the greatest number of taxonomic groups. All these impacts are expected to grow in importance in the future, especially climate change and habitat degradation. The spatial identification of hot spots highlighted the ecological importance of most of the western Mediterranean shelves (and in particular, the Strait of Gibraltar and the adjacent Alboran Sea), western African coast, the Adriatic, and the Aegean Sea, which show high concentrations of endangered, threatened, or vulnerable species. The Levantine Basin, severely impacted by the invasion of species, is endangered as well