28,302 research outputs found
A numerical study of diffusive shock acceleration of cosmic rays in supernova shocks
The evolution of the energy spectrum of cosmic rays accelerated by the first order Fermi mechanism, by a supernova remnant shock wave, including adiabatic deceleration effects behind the front, is carried out by means of a time-dependent numerical code. The calculations apply to the adiabatic stage (or Sedov stage) of the supernova explosion, and the energetic particle spectrum is calculated in the test particle limit (i.e., the back reaction of the cosmic rays on the flow is not included). The particles are injected mono-energetically at the shock. The radial distribution, The radial distribution, and the spectrum of the accelerated and decelerated particles is shown
Partonic effects on higher-order anisotropic flows in relativistic heavy-ion collisions
Higher-order anisotropic flows and in heavy ion collisions at
the Relativistic Heavy Ion Collider are studied in a multiphase transport model
that has previously been used successfully for describing the elliptic flow
in these collisions. We find that the same parton scattering cross
section of about 10 \textrm{mb} used in explaining the measured can also
reproduce the recent data on and from Au + Au collisions at
\textrm{AGeV}. It is further found that the is a more
sensitive probe of the initial partonic dynamics in these collisions than
. Moreover, higher-order parton anisotropic flows are nonnegligible and
satisfy the scaling relation , which
leads naturally to the observed similar scaling relation among hadron
anisotropic flows when the coalescence model is used to describe hadron
production from the partonic matter.Comment: 5 pages, 3 figures, version to appear in PRC as a Rapid Communicatio
Contribution of through the QCD anomaly in exclusive decays and
We compute the decay rates for the exclusive decays and in a QCD-improved factorization framework by including the
contribution from the process through
the QCD anomaly. This method provides an alternative estimate of the
contribution to these decays as
compared to the one using the intrinsic charm content of the
and mesons determined through the decays . The resulting branching ratios are compared with the CLEO
data on and
and predictions are made for the rest.Comment: 16 pages including 4 postscript figures; uses epsfig. The most recent
branching ratios from CLEO, ref. [5], are taken into account. The theory part
is unchange
Hadron production from quark coalescence and jet fragmentation in intermediate energy collisions at RHIC
Transverse momentum spectra of pions, protons and antiprotons in Au+Au
collisions at intermediate RHIC energy of GeV are studied in
a model that includes both quark coalescence from the dense partonic matter and
fragmentation of the quenched perturbative minijet partons. The resulting
baryon to meson ratio at intermediate transverse momenta is predicted to be
larger than that seen in experiments at higher center of mass energies.Comment: 6 pages, 2 figures. Figures replaced to differentially address the
high-pT behavior of baryon versus antibaryon to meson ratio
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Antrodia cinnamomea reduces obesity and modulates the gut microbiota in high-fat diet-fed mice.
BackgroundObesity is associated with gut microbiota dysbiosis, disrupted intestinal barrier and chronic inflammation. Given the high and increasing prevalence of obesity worldwide, anti-obesity treatments that are safe, effective and widely available would be beneficial. We examined whether the medicinal mushroom Antrodia cinnamomea may reduce obesity in mice fed with a high-fat diet (HFD).MethodsMale C57BL/6J mice were fed a HFD for 8 weeks to induce obesity and chronic inflammation. The mice were treated with a water extract of A. cinnamomea (WEAC), and body weight, fat accumulation, inflammation markers, insulin sensitivity and the gut microbiota were monitored.ResultsAfter 8 weeks, the mean body weight of HFD-fed mice was 39.8±1.2 g compared with 35.8±1.3 g for the HFD+1% WEAC group, corresponding to a reduction of 4 g or 10% of body weight (P<0.0001). WEAC supplementation reduced fat accumulation and serum triglycerides in a statistically significant manner in HFD-fed mice. WEAC also reversed the effects of HFD on inflammation markers (interleukin-1β, interleukin-6, tumor necrosis factor-α), insulin resistance and adipokine production (leptin and adiponectin). Notably, WEAC increased the expression of intestinal tight junctions (zonula occludens-1 and occludin) and antimicrobial proteins (Reg3g and lysozyme C) in the small intestine, leading to reduced blood endotoxemia. Finally, WEAC modulated the composition of the gut microbiota, reducing the Firmicutes/Bacteroidetes ratio and increasing the level of Akkermansia muciniphila and other bacterial species associated with anti-inflammatory properties.ConclusionsSupplementation with A. cinnamomea produces anti-obesogenic, anti-inflammatory and antidiabetic effects in HFD-fed mice by maintaining intestinal integrity and modulating the gut microbiota
Spontaneous Ratchet Effect in a Granular Gas
The spontaneous clustering of a vibrofluidized granular gas is employed to
generate directed transport in two different compartmentalized systems: a
"granular fountain" in which the transport takes the form of convection rolls,
and a "granular ratchet" with a spontaneous particle current perpendicular to
the direction of energy input. In both instances, transport is not due to any
system-intrinsic anisotropy, but arises as a spontaneous collective symmetry
breaking effect of many interacting granular particles. The experimental and
numerical results are quantitatively accounted for within a flux model.Comment: 4 pages, 5 figures; Fig. 4 has been reduced in size and qualit
Three Dimensional Structure and Energy Balance of a Coronal Mass Ejection
The Ultraviolet Coronagraph Spectrometer (UVCS) observed Doppler shifted
material of a partial Halo Coronal Mass Ejection (CME) on December 13 2001. The
observed ratio of [O V]/O V] is a reliable density diagnostic important for
assessing the state of the plasma. Earlier UVCS observations of CMEs found
evidence that the ejected plasma is heated long after the eruption. We have
investigated the heating rates, which represent a significant fraction of the
CME energy budget. The parameterized heating and radiative and adiabatic
cooling have been used to evaluate the temperature evolution of the CME
material with a time dependent ionization state model. The functional form of a
flux rope model for interplanetary magnetic clouds was also used to
parameterize the heating. We find that continuous heating is required to match
the UVCS observations. To match the O VI-bright knots, a higher heating rate is
required such that the heating energy is greater than the kinetic energy. The
temperatures for the knots bright in Ly and C III emission indicate
that smaller heating rates are required for those regions. In the context of
the flux rope model, about 75% of the magnetic energy must go into heat in
order to match the O VI observations. We derive tighter constraints on the
heating than earlier analyses, and we show that thermal conduction with the
Spitzer conductivity is not sufficient to account for the heating at large
heights.Comment: 40 pages, 16 figures, accepted for publication in ApJ For associated
mpeg file, please see https://www.cora.nwra.com/~jylee/mpg/f5.mp
Lymphotoxins and cytomegalovirus cooperatively induce interferon-beta, establishing host-virus détente
Tumor necrosis factor (TNF)-related cytokines regulate cell death and survival and provide strong selective pressures for viruses, such as cytomegalovirus (CMV), to evolve counterstrategies in order to persist in immune-competent hosts. Signaling by the lymphotoxin (LT)-β receptor or TNF receptor-1, but not Fas or TRAIL receptors, inhibits the cytopathicity and replication of human CMV by a nonapoptotic, reversible process that requires nuclear factor κB (NF-κB)-dependent induction of interferon-β (IFN-β). Efficient induction of IFN-β requires virus infection and LT signaling, demonstrating the need for both host and viral factors in the curtailment of viral replication without cellular elimination. LTα-deficient mice and LTβR-Fc transgenic mice were profoundly susceptible to murine CMV infection. Together, these results reveal an essential and conserved role for LTs in establishing host defense to CMV
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