IS A BEEF DEFICIENCY PAYMENT PARETO-SUPERIOR IN SOUTH KOREA?

South Korea uses a quota and a tariff on beef imports to keep farm prices high. Part of the quota rents are used to support indirect benefits to producers. The welfare costs of these policies are analyzed. Following a suggestion of Hayami, a deficiency payment financed by tariff revenues from increased imports is considered as an alternative to the quota. As Anderson (1983) found for Japan, a deficiency payment is Pareto-superior only if indirect benefits from the quota revenue are ignored.International Relations/Trade,

Ecogeographical variations of chromosomal polymorphism in Hawaiian populations of Drosophila immigrans

Reports were scanned in black and white at a resolution of 600 dots per inch and were converted to text using Adobe Paper Capture Plug-in.Eighteen samples from twelve populations of Drosophila immigrans in the islands of Kauai, Oahu and Hawaii in the Hawaiian archipelago were analyzed for inversion polymorphism in 1125 females and 206 males. Three kinds of second chromosome inversions, which appear to be identical with those previously reported by other workers, were present in all of our populations; two other new inversions of the same autosome were detected from the Hawaii collections, but their origin, whether natural or laboratory, could not be assured. The average proportion of inversion heterozygosity per individual of the populations from Kauai, Oahu and Hawaii was about 34%, 32% and 65% respectively. The frequencies of heterozygous inversions Here similar between different populations within islands (with one notable exception on Hawaii). In contrast, the frequencies were significantly heterogeneous from one island to the next. The results of gene arrangement frequency analysis consolidated the above findings. It is suggested that the inter-island differentiations are due to natural selection and probably maintained by the isolation by oceanic channels. Two near-by localities on Hawaii were inhabited with significantly heterogeneous populations. Such a microgeographic differentiation has been interpreted as being due to the presence of highly localized, differential selection forces in the two localities, and the difference seems to be maintained due to isolation by the lava flows. Our data suggest that the breeding units of Hawaiian populations of D. immigrans are not so small as to allow for genetic drift to significantly affect the populations. Inversion polymorphism was similar between females and males taken at the same time in the same localities

FINAL ICONE17-75007 ANALYSIS OF FIV CHARACTERISTICS ON A COAXIAL DOUBLE-TUBE TYPE HOT GAS DUCT FOR THE VHTR

ABSTRACT The Very High Temperature Gas Cooled Reactor (VHTR) has been selected as a high energy heat source of the order of 950℃ for nuclear hydrogen generation, which can produce hydrogen from water or natural gas. A primary hot gas duct (HGD) as a coaxial double-tube type cross vessel is a key component connecting the reactor pressure vessel and the intermediate heat exchanger in a VHTR. In this study, a structural sizing methodology for the primary HGD of a VHTR is suggested in order to modulate a flow-induced vibration (FIV). And as an example, a structural sizing of a horizontal HGD with a coaxial double-tube structure was carried out using the suggested method. These activities include a decision of the geometric dimensions, a selection of the material, and a evaluation of the strength of the coaxial double-tube type cross vessel components. Also in order to compare the FIV characteristics of the proposed design cases, a fluid-structure interaction (FSI) analysis on a quarter part of the HGD was carried out using the ADINA code. INTRODUCTION The Very High Temperature Gas Cooled Reactor (VHTR) has been selected as a high energy heat source for nuclear hydrogen generation, which can produce hydrogen from heat and water by using a thermo-chemical process or from heat, water, and natural gas by steam reformer technology or using a high temperature electrolysis of steam. The nuclear hydrogen system being researched at KAERI is planning to produce hydrogen in the order of 950℃ by using nuclear energy and a thermo-chemical process. Helium gas is tentatively considered as the choice for the coolant of the nuclear hydrogen system since it is an inert gas, with no affinity to a chemical or nuclear activity; therefore the transport of radioactivity in the primary circuit of the nuclear hydrogen system is minimal under a normal operation. Moreover, its gaseous nature avoids the problems related to a phase change and water-metal reactions and therefore improves its safety. A hot gas duct (HGD) is a key component connecting the reactor pressure vessel and the intermediate heat exchanger (IHX) in a VHTR as shown i

Half-quantum vortex and d-soliton in Sr2_2RuO4_4

Assuming that the superconductivity in Sr$_2$RuO$_4$ is described by a planar p-wave order parameter, we consider possible topological defects in Sr$_2$RuO$_4$. In particular, it is shown that both of the ${\hat d}$-soliton and half-quantum vortex can be created in the presence of the magnetic field parallel to the $a$-$b$ plane. We discuss how one can detect the ${\hat d}$-soliton and half-quantum vortex experimentally.Comment: 8 pages, 3 figure

Batalin-Tyutin Quantization of the Self-Dual Massive Theory in Three Dimensions

We quantize the self-dual massive theory by using the Batalin-Tyutin Hamiltonian method, which systematically embeds second class constraint system into first class one in the extended phase space by introducing the new fields. Through this analysis we obtain simultaneously the St\"uckelberg scalar term related to the explicit gauge-breaking effect and the new type of Wess-Zumino action related to the Chern-Simons term.Comment: 17 pages, SOGANG-HEP 191/9

Integrated Transcriptomics, Metabolomics, and Lipidomics Profiling in Rat Lung, Blood, and Serum for Assessment of Laser Printer-Emitted Nanoparticle Inhalation Exposure-Induced Disease Risks

settings Open AccessArticle Integrated Transcriptomics, Metabolomics, and Lipidomics Profiling in Rat Lung, Blood, and Serum for Assessment of Laser Printer-Emitted Nanoparticle Inhalation Exposure-Induced Disease Risks by Nancy Lan Guo 1,*,Tuang Yeow Poh 2,Sandra Pirela 3,Mariana T. Farcas 4,Sanjay H. Chotirmall 2,Wai Kin Tham 5,Sunil S. Adav 5,Qing Ye 1,Yongyue Wei 6,Sipeng Shen 2,David C. Christiani 2,Kee Woei Ng 3,7,8,Treye Thomas 9,Yong Qian 4 andPhilip Demokritou 3 1 West Virginia University Cancer Institute/School of Public Health, West Virginia University, Morgantown, WV 26506, USA 2 Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore 3 Center for Nanotechnology and Nanotoxicology, Department of Environmental Health, T. H. Chan School of Public Health, Harvard University, Boston, MA 02115, USA 4 Pathology and Physiology Research Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA 5 Singapore Phenome Centre, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore 6 Key Lab for Modern Toxicology, Department of Epidemiology and Biostatistics and Ministry of Education (MOE), School of Public Health, Nanjing Medical University, Nanjing 210029, China 7 School of Materials Science and Engineering, Nanyang Technological University, Singapore 639798, Singapore 8 Environmental Chemistry and Materials Centre, Nanyang Environment & Water Research Institute, Singapore 637141, Singapore 9 Office of Hazard Identification and Reduction, U.S. Consumer Product Safety Commission, Rockville, MD 20814, USA * Author to whom correspondence should be addressed. Int. J. Mol. Sci. 2019, 20(24), 6348; https://doi.org/10.3390/ijms20246348 Received: 2 December 2019 / Revised: 12 December 2019 / Accepted: 13 December 2019 / Published: 16 December 2019 (This article belongs to the Special Issue Advances in Nanostructured Materials between Pharmaceutics and Biomedicine) Download PDF Browse Figures Review Reports Cite This Paper Abstract Laser printer-emitted nanoparticles (PEPs) generated from toners during printing represent one of the most common types of life cycle released particulate matter from nano-enabled products. Toxicological assessment of PEPs is therefore important for occupational and consumer health protection. Our group recently reported exposure to PEPs induces adverse cardiovascular responses including hypertension and arrythmia via monitoring left ventricular pressure and electrocardiogram in rats. This study employed genome-wide mRNA and miRNA profiling in rat lung and blood integrated with metabolomics and lipidomics profiling in rat serum to identify biomarkers for assessing PEPs-induced disease risks. Whole-body inhalation of PEPs perturbed transcriptional activities associated with cardiovascular dysfunction, metabolic syndrome, and neural disorders at every observed time point in both rat lung and blood during the 21 days of exposure. Furthermore, the systematic analysis revealed PEPs-induced transcriptomic changes linking to other disease risks in rats, including diabetes, congenital defects, auto-recessive disorders, physical deformation, and carcinogenesis. The results were also confirmed with global metabolomics profiling in rat serum. Among the validated metabolites and lipids, linoleic acid, arachidonic acid, docosahexanoic acid, and histidine showed significant variation in PEPs-exposed rat serum. Overall, the identified PEPs-induced dysregulated genes, molecular pathways and functions, and miRNA-mediated transcriptional activities provide important insights into the disease mechanisms. The discovered important mRNAs, miRNAs, lipids and metabolites may serve as candidate biomarkers for future occupational and medical surveillance studies. To the best of our knowledge, this is the first study systematically integrating in vivo, transcriptomics, metabolomics, and lipidomics to assess PEPs inhalation exposure-induced disease risks using a rat model

Fractionalization patterns in strongly correlated electron systems: Spin-charge separation and beyond

We discuss possible patterns of electron fractionalization in strongly interacting electron systems. A popular possibility is one in which the charge of the electron has been liberated from its Fermi statistics. Such a fractionalized phase contains in it the seed of superconductivity. Another possibility occurs when the spin of the electron, rather than its charge, is liberated from its Fermi statistics. Such a phase contains in it the seed of magnetism, rather than superconductivity. We consider models in which both of these phases occur and study possible phase transitions between them. We describe other fractionalized phases, distinct from these, in which fractions of the electron themselves fractionalize, and discuss the topological characterization of such phases. These ideas are illustrated with specific models of p-wave superconductors, Kondo lattices, and coexistence between d-wave superconductivity and antiferromagnetism.Comment: 28 pages, 11 fig

Effect of Ring Exchange on Orbital Antiferromagnet

We study the effect of four-particle ring exchange process on orbital antiferromagnetic state that occurs in some correlated electron systems in two dimensions. The primary question is whether the ring exchange process enhances or suppresses the orbital antiferromagnetic ordering. Using the fact that the orbital antiferromagnetic state arises in the large-N limit of the SU(N) generalization of the t-J model, we consider the large-N limit of the t-J-$K$ model where $K$ represents the four-particle ring exchange term. The phase diagrams in the large-N mean field theory are obtained for the half-filling and finite hole concentrations at zero temperature. It is found that the ring exchange in general favors dimerized states or the inhomogeneous orbital antiferromagnetic state, and suppresses the homogeneous orbital antiferromagnetic state. We compare our results with other related models of strongly correlated systems with ring exchange processes.Comment: 14 pages, 17 figure

The nuclear immune receptor RPS4 is required for RRS1SLH1-dependent constitutive defense activation in Arabidopsis thaliana

Plant nucleotide-binding leucine-rich repeat (NB-LRR) disease resistance (R) proteins recognize specific ‘‘avirulent’’ pathogen effectors and activate immune responses. NB-LRR proteins structurally and functionally resemble mammalian Nod-like receptors (NLRs). How NB-LRR and NLR proteins activate defense is poorly understood. The divergently transcribed Arabidopsis R genes, RPS4 (resistance to Pseudomonas syringae 4) and RRS1 (resistance to Ralstonia solanacearum 1), function together to confer recognition of Pseudomonas AvrRps4 and Ralstonia PopP2. RRS1 is the only known recessive NBLRR R gene and encodes a WRKY DNA binding domain, prompting suggestions that it acts downstream of RPS4 for transcriptional activation of defense genes. We define here the early RRS1-dependent transcriptional changes upon delivery of PopP2 via Pseudomonas type III secretion. The Arabidopsis slh1 (sensitive to low humidity 1) mutant encodes an RRS1 allele (RRS1SLH1) with a single amino acid (leucine) insertion in the WRKY DNA-binding domain. Its poor growth due to constitutive defense activation is rescued at higher temperature. Transcription profiling data indicate that RRS1SLH1-mediated defense activation overlaps substantially with AvrRps4- and PopP2-regulated responses. To better understand the genetic basis of RPS4/RRS1-dependent immunity, we performed a genetic screen to identify suppressor of slh1 immunity (sushi) mutants. We show that many sushi mutants carry mutations in RPS4, suggesting that RPS4 acts downstream or in a complex with RRS1. Interestingly, several mutations were identified in a domain C-terminal to the RPS4 LRR domain. Using an Agrobacterium-mediated transient assay system, we demonstrate that the P-loop motif of RPS4 but not of RRS1SLH1 is required for RRS1SLH1 function. We also recapitulate the dominant suppression of RRS1SLH1 defense activation by wild type RRS1 and show this suppression requires an intact RRS1 P-loop. These analyses of RRS1SLH1 shed new light on mechanisms by which NB-LRR protein pairs activate defense signaling, or are held inactive in the absence of a pathogen effector

Prescribing patterns of low doses of antipsychotic medications in older Asian patients with schizophrenia, 2001-2009

Background: This study examined the use of low doses of antipsychotic medications (300mg/day CPZeq or less) in older Asian patients with schizophrenia and its demographic and clinical correlates. Methods: Information on hospitalized patients with schizophrenia, aged 55 years or older, was extracted from the database of the Research on Asian Psychotropic Prescription Patterns (REAP) study (2001-2009). Data on 1,452 patients in eight Asian countries and territories including China, Hong Kong, Japan, Korea, Singapore, Taiwan, India, and Malaysia were analyzed. Sociodemographic and clinical characteristics and antipsychotic prescriptions were recorded using a standardized protocol and data collection procedure. Results: The prescription frequency for low doses of antipsychotic medications was 40.9% in the pooled sample. Multiple logistic regression analysis of the whole sample showed that patients on low doses of antipsychotic medications were more likely to be female, have an older age, a shorter length of illness, and less positive symptoms. Of patients in the six countries and territories that participated in all the surveys between 2001 and 2009, those in Japan were less likely to receive low doses of antipsychotics. Conclusion: Low doses of antipsychotic medications were only applied in less than half of older Asian patients with schizophreni