Anti-inflammatory effect of phytoestrogens from hydroalcoholic extract of water (mauritia flexuosa) in ovariectomized rats

Introducción: Los fitoestrógenos, aparentemente tienen semejanza en cuanto a su estructura química con los estrógenos. La disminución de la concentración de estrógenos durante la menopausia se correlaciona con un número reducido de células B y T y una mayor secreción de citoquinas proinflamatorias. Objetivos: Determinar el efecto antiinflamatorio del extracto hidroalcohólico del aguaje (Mauritia flexuosa) en ratas wistar ovariectomizadas. Material y métodos: Se utilizaron 20 ratas hembras. Grupo 1: ratas hembras intactas + NaCl 1ml/100gr. Grupo 2: ratas OVX + Etinilestradiol 50 um/Kg. Grupo 3: OVX + EHA de 300 mg/Kg. Grupo 4: OVX + EHA 500mg/Kg. Luego de recibir el tratamiento  se inyectó 0.1 ml de carragenina al 1% en la superficie de una pata trasera para obtener los datos en el incremento del diámetro del miembro inferior con ayuda de micrómetro. Resultados: Se usó la prueba estadística Anova en donde se observa la inflamación producida por la carragenina y en la prueba estadística de Dunn se obtuvo una diferencia estadísticamente significativa (P=< 0.01) Conclusiones: Se detectó que el extracto de Mauritia flexuosa tiene un efecto antiinflamatorio después de una administración continua.Introduction: Phytoestrogens apparently have a similarity in terms of their chemical structure with estrogens. The decrease in estrogen concentration during menopause correlates with reduced numbers of B and T cells and increased secretion of proinflammatory cytokines. Objective: To determine the anti-inflammatory effect of the hydroalcoholic extract of aguaje (Mauritia flexuosa) in ovariectomized wistar rats. Material and methods: 20 female rats were used. Group 1: intact female rats + NaCl 1ml/100gr. Group 2: OVX rats + Ethinylestradiol 50 um/Kg. Group 3: OVX + EHA of 300 mg/Kg. Group 4: OVX + EHA 500mg/Kg. After receiving the treatment, 0.1 ml of 1% carrageenan was injected into the surface of a hind leg to obtain data on the increase in the diameter of the lower limb with the help of a micrometer. Results: The Anova statistical test was used where the inflammation produced by carrageenan was observed and a statistically significant difference was obtained in Dunn's statistical test (P=<0.01). Conclusions: It was detected that the extract of Mauritia flexuosa has an effect anti-inflammatory after continuous administration

Tenis. Ejercicios progresivos para desarrollar tu juego

G. Torres Luque, A. Sánchez Pay, C. Gago Fuentes y J. Ros García (2013). Badalona: Paidotrib

Probing the innermost regions of AGN jets and their magnetic fields with RadioAstron II. Observations of 3C 273 at minimum activity

RadioAstron is a 10 m orbiting radio telescope mounted on the Spektr-R satellite, launched in 2011, performing Space Very Long Baseline Interferometry (SVLBI) observations supported by a global ground array of radio telescopes. With an apogee of about 350 000 km, it is offering for the first time the possibility to perform {\mu}as-resolution imaging in the cm-band. We present observations at 22 GHz of 3C 273, performed in 2014, designed to reach a maximum baseline of approximately nine Earth diameters. Reaching an angular resolution of 0.3 mas, we study a particularly low-activity state of the source, and estimate the nuclear region brightness temperature, comparing with the extreme one detected one year before during the RadioAstron early science period. We also make use of the VLBA-BU-BLAZAR survey data, at 43 GHz, to study the kinematics of the jet in a 1.5-year time window. We find that the nuclear brightness temperature is two orders of magnitude lower than the exceptionally high value detected in 2013 with RadioAstron at the same frequency (1.4x10^13 K, source-frame), and even one order of magnitude lower than the equipartition value. The kinematics analysis at 43 GHz shows that a new component was ejected 2 months after the 2013 epoch, visible also in our 22 GHz map presented here. Consequently this was located upstream of the core during the brightness temperature peak. These observations confirm that the previously detected extreme brightness temperature in 3C 273, exceeding the inverse Compton limit, is a short-lived phenomenon caused by a temporary departure from equipartition. Thus, the availability of interferometric baselines capable of providing {\mu}as angular resolution does not systematically imply measured brightness temperatures over the known physical limits for astrophysical sources.Comment: Accepted for publication in A&

LA FIGURA DEL EDUCADOR SOCIAL

At the moment we are attending the origin of new social, cultural and demographic situations that they make sprout in the professionals of the education new concerns of attention and formative development. In this article reference is made to diverse characteristic that can characterize one of these professionals: the social educator.Actualmente estamos asistiendo al origen de nuevas situaciones sociales, culturales y demográficas que hacen brotar en los profesionales de la educación nuevas preocupaciones de atención y desarrollo formativo. En este artículo se hace referencia a diversas características que pueden caracterizar a uno de estos profesionales: el educador social

DIMENSIONES, RASGOS Y RELACIONES DEL LÍDER Y SU GRUPO: LIDERAZGO VERSUS AUTONOMÍA

The current times lead to see the boss like an equal, inclusive to criticize it and challenge it. In last years the boss had support and respect and saw you like a superior; now the boss should have the ability in order to manage situations and try to their “employees” appropriately in order to earn their obedience and loyalty so, this is a merit that could only obtain the one that it is leader. We in this article are going to attempt make a brief journey for the different dimension and types of leadership, the common personnels that characterize a leader and the relationships between the leader and their group.Los tiempos actuales llevan a ver al jefe como un igual, inclusive a criticarlo y desafiarlo. En años pasados el jefe contaba con apoyo y respeto y se le veía como un superior; ahora el jefe debe contar con la habilidad para manejar situaciones y tratar a sus “empleados” adecuadamente para ganarse así su obediencia y lealtad, éste es un mérito que sólo puede obtener el que es líder. En este artículo vamos a intentar hacer un breve recorrido por las distintas dimensiones y tipos de liderazgo, los rasgos personales que caracterizan a un líder y las relaciones entre el líder y su grupo

The Transit Light Curve Project. IV. Five Transits of the Exoplanet OGLE-TR-10b

We present I and B photometry of five distinct transits of the exoplanet OGLE-TR-10b. By modeling the light curves, we find the planetary radius to be R_P = 1.06 +/- 0.08 R_Jup and the stellar radius to be R_S = 1.10 +/- 0.07 R_sun. The uncertainties are dominated by statistical errors in the photometry. Our estimate of the planetary radius is smaller than previous estimates that were based on lower-precision photometry, and hence the planet is not as anomalously large as was previously thought. We provide updated determinations of all the system parameters, including the transit ephemerides

Comparison of performances between risk scores for predicting mortality at 30 days in patients with community acquired pneumonia

Background: Risk scores facilitate the assessment of mortality risk in patients with community-acquired pneumonia (CAP). Despite their utilities, there is a scarcity of evidence comparing the various RS simultaneously. This study aims to evaluate and compare multiple risk scores reported in the literature for predicting 30-day mortality in adult patients with CAP. Methods: A retrospective cohort study on patients diagnosed with CAP was conducted across two hospitals in Colombia. The areas under receiver operating characteristic curves (ROC-curves) were calculated for the outcome of survival or death at 30 days using the scores obtained for each of the analyzed questionnaires. Results: A total of 7454 potentially eligible patients were included, with 4350 in the final analysis, of whom 15.2% (662/4350) died within 30 days. The average age was 65.4 years (SD: 21.31), and 59.5% (2563/4350) were male. Chronic kidney disease was 3.7% (9.2% vs. 5.5%; p < 0.001) (OR: 1.85) higher in subjects who died compared to those who survived. Among the patients who died, 33.2% (220/662) presented septic shock compared to 7.3% (271/3688) of the patients who survived (p < 0.001). The best performances at 30 days were shown by the following scores: PSI, SMART-COP and CURB 65 scores with the areas under ROC-curves of 0.83 (95% CI: 0.8–0.85), 0.75 (95% CI: 0.66–0.83), and 0.73 (95% CI: 0.71–0.76), respectively. The RS with the lowest performance was SIRS with the area under ROC-curve of 0.53 (95% CI: 0.51–0.56). Conclusion: The PSI, SMART-COP and CURB 65, demonstrated the best diagnostic performances for predicting 30-day mortality in patients diagnosed with CAP. The burden of comorbidities and complications associated with CAP was higher in patients who died

North American pitseed goosefoot (Chenopodium berlandieri) is a genetic resource to improve Andean quinoa (C. quinoa)

Pitseed goosefoot (Chenopodium berlandieri) is a free-living North American member of an allotetraploid complex that includes the Andean pseudocereal quinoa (C. quinoa). Like quinoa, pitseed goosefoot was domesticated, possibly independently, in eastern North America (subsp. jonesianum) and Mesoamerica (subsp. nuttaliae). To test the utility of C. berlandieri as a resource for quinoa breeding, we produced the whole-genome DNA sequence of PI 433,231, a huauzontle from Puebla, México. The 1.295 Gb genome was assembled into 18 pseudomolecules and annotated using RNAseq data from multiple tissues. Alignment with the v.2.0 genome of Chilean-origin C. quinoa cv. ‘QQ74’ revealed several inversions and a 4A-6B reciprocal translocation. Despite these rearrangements, some quinoa x pitseed goosefoot crosses produce highly fertile hybrids with faithful recombination, as evidenced by a high-density SNP linkage map constructed from a Bolivian quinoa ‘Real-1’ × BYU 937 (Texas coastal pitseed goosefoot) F2 population. Recombination in that cross was comparable to a ‘Real-1’ × BYU 1101 (Argentine C. hircinum) F2 population. Furthermore, SNP-based phylogenetic and population structure analyses of 90 accessions supported the hypothesis of multiple independent domestications and descent from a common 4 × ancestor, with a likely North American Center of Origin.Fil: Maughan, Peter J.. University Brigham Young; Estados UnidosFil: Jarvis, David E.. University Brigham Young; Estados UnidosFil: de la Cruz Torres, Eulogio. University Brigham Young; Estados UnidosFil: Jaggi, Kate E.. University Brigham Young; Estados UnidosFil: Warner, Heather C.. University Brigham Young; Estados UnidosFil: Marcheschi, Ashley K.. University Brigham Young; Estados UnidosFil: Bertero, Hector Daniel. Universidad de Buenos Aires. Facultad de Agronomía. Departamento de Producción Vegetal. Cátedra de Producción Vegetal; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Gomez Pando, Luz. University Brigham Young; Estados UnidosFil: Fuentes, Francisco. University Brigham Young; Estados UnidosFil: Mayta Anco, Mayela E.. University Brigham Young; Estados UnidosFil: Curti, Ramiro Nestor. Universidad Nacional de Salta. Facultad de Ciencias Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Rey, Elodie. University Brigham Young; Estados UnidosFil: Tester, Mark. University Brigham Young; Estados UnidosFil: Jellen, Eric N.. University Brigham Young; Estados Unido

Propiedades fisicoquímicas y actividad antioxidante de chiltepín cultivado bajo mallas sombra de colores.

En la última década han surgido en el mercado mallas de colores que debido a sus propiedades fotosintéticas que mejoran el aprovechamiento de la radiación solar en los cultivos protegidos. En este trabajo se evaluó la influencia de mallas sombra sobre las propiedades fisicoquímicas y actividad antioxidante de frutos de chiltepín. Se determinaron las siguientes variables de estudio; pH, Sólidos solubles totales, acidez titulable, color, vitamina “C” y actividad antioxidante por DPPH. El diseño experimental utilizado fue completamente al azar y la prueba de comparaciones de medias de Tukey (p≤ 0.05). No se observaron diferencias significativas en acidez titulable. Se observó una mayor brillantez en los frutos de chiltepín cultivados bajo invernadero, mientras que el mayor valor de a* y Croma se observó en los frutos de chiltepín cultivado bajo malla azul. El mayor contenido de sólidos solubles totales se observó en los frutos cultivados bajo malla roja, y el mayor contenido de vitamina “C”, se observó en los frutos de chiltepín cultivados en campo y bajo malla sombra de color azul, sin embargo la mayor actividad antioxidante se observó en los frutos cultivados en campo y bajo invernadero