815 research outputs found

    Data on geochemical and hydraulic properties of a characteristic confined/unconfined aquifer system of the younger Pleistocene in northeast Germany

    Get PDF
    The paper presents a database of hydrochemical and hydraulic groundwater measurements of a younger Pleistocene multilayered, unconfined/confined aquifer system in NE Germany. The Institute of Landscape Hydrology of the Leibniz Centre for Agricultural Landscape Research (ZALF) operates seven groundwater monitoring wells in the Quillow catchment located in the Uckermark region (federal state of Brandenburg, Germany). From July 2000 to March 2014, water samples were collected periodically on different days of the year and at depths between 3 and 5 m (shallow wells) and 16 and 24 m (deeper wells) below the surface. The parameters pH value, redox potential, electric conductivity, water temperature, oxygen content, spectral absorption coefficient and concentration of hydrogen carbonate, ammonium, phosphate, chloride, bromide, nitrite, sulfate, sodium, potassium, magnesium, calcite, dissolved organic carbon, iron(II) and manganese were determined for each sample (doi:10.4228/ZALF.2000.266). The measurements, taken over a period of 14 years, include a high variation of hydraulic situations represented by a corresponding database of 19 000 recorded groundwater heads. The hydraulic head was measured between 2000 and 201

    Evolutionär konservierte Gene aus Drosophila melanogaster in humanen Glioblastomen

    Full text link
    Entstehung und Invasivität von Glioblastomen könnte auf evolutionär konservierten Prozessen beruhen. Auf Ebene der Genxpression wurde in humanen Glioblastomen mittels RT-PCR nach Hinweisen auf evolutionär konservierte Mechanismen bei glialer Proliferation und Invasion gesucht. Ausgangspunkt waren Erkenntnisse über das ZNS der Drosophila melanogaster, das aufgrund von strukturellen und molekularen Ähnlichkeiten als Modell für das Vertebraten ZNS herangezogen werden kann. Die Drosophila-Gene BREATHLESS, GLIOTACTIN, KÄSTCHEN, LOCO, NONSTOP, ROBO und SCHIZO führten über BLAST-Recherche zu den humanen Homologen FGFR1 und FGFR2, Neuroligin1, Neuroligin2 und Neuroligin3, LIV-1 und similar to KIAA 1265, RGS12 und RGS 14, USP22 und UBP41, Robo 1, Robo2 und Neogenin sowie EFA6B. Die meisten Gene wurden in Glioblastomen abweichend von normalem Hirngewebe exprimiert, so dass neoplastische Proliferation und Invasion auf evolutionär konservierten Mechanismen beruhen könnte

    Effect of two cleaning processes for bone allografts on gentamicin impregnation and in vitro antibiotic release.

    Get PDF
    Bone allografts are a useful and sometimes indispensable tool for the surgeon to repair bone defects. Microbial contamination is a major reason for discarding allografts from bone banks. To improve the number of safe allografts, we suggest chemical cleaning of the grafts followed by antibiotic impregnation. Comparison of two chemical cleaning processes for bone allografts aiming for antibiotic impregnation and consequently delivery rates in vitro. Bone chips of 5–10 mm were prepared from human femoral heads. Two cleaning methods (cleaning A and cleaning B) based on solutions containing hydrogen peroxide, paracetic acid, ethanol and biological detergent were carried out and compared. After the cleaning processes, the bone chips were impregnated with gentamicin. Bacillus subtilis bioassay was used to determine the gentamicin release after intervals of 1–7 days. Differences were compared with non-parametric Mann–Whitney U tests. The zones of inhibition obtained from the bone grafts cleaned with both cleaning processes were similar between the groups. The concentration of the released antibiotic was decreasing gradually over time, following a similar pattern for both groups. The cleaning procedure A as well as the cleaning procedure B for bone allografts allowed the impregnation with gentamicin powder in the same concentrations in both groups. The delivery of gentamicin was similar for both groups. Both cleaning procedures were easy to be carried out, making them suitable for routine use at the bone banks

    Определение эффективности нейтронного детектора из пластического сцинтиллятора o100?200 мм

    Get PDF
    Рассчитывается и экспериментально проверяется эффективность детектора. к нейтронам сверхвысоких (десятки и сотни МэВ) энергий

    Improved limits on nuebar emission from mu+ decay

    Full text link
    We investigated mu+ decays at rest produced at the ISIS beam stop target. Lepton flavor (LF) conservation has been tested by searching for \nueb via the detection reaction p(\nueb,e+)n. No \nueb signal from LF violating mu+ decays was identified. We extract upper limits of the branching ratio for the LF violating decay mu+ -> e+ \nueb \nu compared to the Standard Model (SM) mu+ -> e+ nue numub decay: BR < 0.9(1.7)x10^{-3} (90%CL) depending on the spectral distribution of \nueb characterized by the Michel parameter rho=0.75 (0.0). These results improve earlier limits by one order of magnitude and restrict extensions of the SM in which \nueb emission from mu+ decay is allowed with considerable strength. The decay \mupdeb as source for the \nueb signal observed in the LSND experiment can be excluded.Comment: 10 pages, including 1 figure, 1 tabl
    corecore