Final analysis/design and prototype construction of a selected mobility and restraint device Final report

Underwater tests of prototype construction of selected mobility and restraint devic

A Good SCAM for Building Connections: Scholarly Communications Activity Mapping

Are you looking for new ways to connect with faculty? Do you know how to best support faculty publishing? Grand Valley State University Libraries has developed a scholarly activity mapping template to document current scholarly and creative practices of faculty. The data gathered can be used to identify unmet faculty scholarly needs and reveal new opportunities to build relationships with faculty. Over the last several years, our liaison librarians have worked to closely integrate library instruction services into the curriculum of their liaison areas through the use of instruction plans. At the same time our research and publishing support expanded, largely driven by faculty needs in these areas. These two threads combined in 2016 as a group of librarians collaborated to develop a framework for exploring and documenting research practices across the university. By mapping current scholarly activity, we are gathering information that can strengthen library connections with faculty, identify needs our services can meet, and inform our instruction and collection development. A few liaison librarians are piloting this new scholarly activity map for the 2016-2017 school year. Challenges and lessons learned will be shared, in addition to benefits already noticed and future plans for utilizing these scholarly activity maps more broadly. In this poster presentation we will describe the process of developing our template, challenges we have encountered, and the progress of our pilot project. This poster will be of interest to academic librarians looking for new opportunities to connect with faculty, especially liaison, subject, and scholarly communications librarians. The information and resources we share will help academic libraries grow a scholarly communications program and expand support for faculty research activities. In addition to the poster, we will share copies of our current scholarly activity mapping template and the documents that inspired this project

Development of Multigene Expression Signature Maps at the Protein Level from Digitized Immunohistochemistry Slides

Molecular classification of diseases based on multigene expression signatures is increasingly used for diagnosis, prognosis, and prediction of response to therapy. Immunohistochemistry (IHC) is an optimal method for validating expression signatures obtained using high-throughput genomics techniques since IHC allows a pathologist to examine gene expression at the protein level within the context of histologically interpretable tissue sections. Additionally, validated IHC assays may be readily implemented as clinical tests since IHC is performed on routinely processed clinical tissue samples. However, methods have not been available for automated n-gene expression profiling at the protein level using IHC data. We have developed methods to compute expression level maps (signature maps) of multiple genes from IHC data digitized on a commercial whole slide imaging system. Areas of cancer for these expression level maps are defined by a pathologist on adjacent, co-registered H&E slides, allowing assessment of IHC statistics and heterogeneity within the diseased tissue. This novel way of representing multiple IHC assays as signature maps will allow the development of n-gene expression profiling databases in three dimensions throughout virtual whole organ reconstructions

ВДОСКОНАЛЕННЯ УПРАВЛІННЯ ФІНАНСУВАННЯМ ІННОВАЦІЙНО-ІНВЕСТИЦІЙНОЇ ДІЯЛЬНОСТІ НА ПРОМИСЛОВИХ ПІДПРИЄМСТВАХ

Метою статті є дослідження особливостей фінансових аспектів управління інноваційно-інвестиційною діяльністю промислових підприємств і визначення шляхів підвищення ефективності фінансування ІІДРозкрито сутність і зміст системи управління фінансуванням інноваційно-інвестиційної діяльності на промислових підприємства

Constructing women’s leadership representation in the UK press during a time of financial crisis : gender capitals and dialectical tensions

A continuing challenge for organizations is the persistent underrepresentation of women in senior roles, which gained a particular prominence during the global financial crisis (GFC). The GFC has raised questions regarding the forms of leadership that allowed the crisis to happen and alternative proposals regarding how future crises might be avoided. Within this context women’s leadership has been positioned as an ethical alternative to styles of masculinist leadership that led to the crisis in the first place. Through a multimodal discursive analysis this article examines the socio-cultural assumptions sustaining the gendering of leadership in the popular press to critically analyse how women’s leadership is represented during the GFC of 2008–2012. Highlighting the media’s portrayal of women’s leadership as a gendered field of activity where different forms of gender capital come into play, we identify three sets of dialectics: women as leaders and women as feminine, women as credible leaders and women as lacking in credibility, and women as victims and women as their own worst enemies. Together, the dialectics work together to form a discursive pattern framed by a male leadership model that narrates the promise of women leaders, yet the disappointment that they are not men. Our study extends understandings regarding how female and feminine forms of gender capital operate dialectically, where the media employs feminine capital to promote women’s positioning as leaders yet also leverages female capital as a constraint. We propose that this understanding can be of value to organizations to understand the impact and influence of discourse on efforts to promote women into leadership roles

GAPscreener: An automatic tool for screening human genetic association literature in PubMed using the support vector machine technique

<p>Abstract</p> <p>Background</p> <p>Synthesis of data from published human genetic association studies is a critical step in the translation of human genome discoveries into health applications. Although genetic association studies account for a substantial proportion of the abstracts in PubMed, identifying them with standard queries is not always accurate or efficient. Further automating the literature-screening process can reduce the burden of a labor-intensive and time-consuming traditional literature search. The Support Vector Machine (SVM), a well-established machine learning technique, has been successful in classifying text, including biomedical literature. The GAPscreener, a free SVM-based software tool, can be used to assist in screening PubMed abstracts for human genetic association studies.</p> <p>Results</p> <p>The data source for this research was the HuGE Navigator, formerly known as the HuGE Pub Lit database. Weighted SVM feature selection based on a keyword list obtained by the two-way z score method demonstrated the best screening performance, achieving 97.5% recall, 98.3% specificity and 31.9% precision in performance testing. Compared with the traditional screening process based on a complex PubMed query, the SVM tool reduced by about 90% the number of abstracts requiring individual review by the database curator. The tool also ascertained 47 articles that were missed by the traditional literature screening process during the 4-week test period. We examined the literature on genetic associations with preterm birth as an example. Compared with the traditional, manual process, the GAPscreener both reduced effort and improved accuracy.</p> <p>Conclusion</p> <p>GAPscreener is the first free SVM-based application available for screening the human genetic association literature in PubMed with high recall and specificity. The user-friendly graphical user interface makes this a practical, stand-alone application. The software can be downloaded at no charge.</p

How women in the executive influence government stability

Does the gender of prime ministers and cabinet ministers influence cabinet duration? We argue that the risk for early termination of cabinets decreases with women’s presence in the executive. As scholars of social psychology indicate, women apply more consensual and compromise-oriented conflict resolution strategies. Disputes between or within governing parties, which ultimately lead to early termination, should therefore be less likely to emerge and escalate if the government is led by a woman or includes numerous female members. To test this rationale, we analyse a newly compiled, comprehensive dataset covering 676 governments in 27 European countries between 1945 and 2018 by relying on event history analysis. The results suggest that cabinets with a higher proportion of female cabinet members experience a lower risk of early cabinet termination. This article contributes to the study of women as political leaders through additional evidence for the gendered nature of leadership styles

Effective healthcare teams require effective team members: defining teamwork competencies

BACKGROUND: Although effective teamwork has been consistently identified as a requirement for enhanced clinical outcomes in the provision of healthcare, there is limited knowledge of what makes health professionals effective team members, and even less information on how to develop skills for teamwork. This study identified critical teamwork competencies for health service managers. METHODS: Members of a state branch of the professional association of Australian health service managers participated in a teamwork survey. RESULTS: The 37% response rate enabled identification of a management teamwork competency set comprising leadership, knowledge of organizational goals and strategies and organizational commitment, respect for others, commitment to working collaboratively and to achieving a quality outcome. CONCLUSION: Although not part of the research question the data suggested that the competencies for effective teamwork are perceived to be different for management and clinical teams, and there are differences in the perceptions of effective teamwork competencies between male and female health service managers. This study adds to the growing evidence that the focus on individual skill development and individual accountability and achievement that results from existing models of health professional training, and which is continually reinforced by human resource management practices within healthcare systems, is not consistent with the competencies required for effective teamwork

Large-eddy simulation of kerosene spray combustion in a model scramjet chamber

Large-eddy simulation (LES) of kerosene spray combustion in a model supersonic combustor with cavity flame holder is carried out. Kerosene is injected through the ceiling of the cavity. The subgrid-scale (SGS) turbulence stress ensor is closed via the Smagorinsky’s eddyviscosity model, chemical source terms are modelled by a finite rate chemistry (FRC) model, and a four-step reduced kerosene combustion kinetic mechanism is adopted. The chamber wallpressure predicted from the LES is validated by experimental data reported in literature. The test case has a cavity length of 77mm and a depth of 8mm. After liquid kerosene is injected through the orifice, most of the droplets are loaded with recirculation fluid momentum inside the cavity. Due to lower velocity of the carrier fluid inside the cavity, sufficient atomization and evaporation take place during the process of droplet transportation, resulting in a rich fuel mixture of kerosene vapour accumulating inside the cavity. These rich fuel mixtures are mixed with fresh air by the approachmixing layer at the front of the cavity and are thus involved in burning accompanied with the approach boundary layer separation extending towards upstream. The combustion flame in the downstream impinges onto the rear wall of the cavity and is then reflected back to the front of the cavity. During the recirculation of hot flow, heat is compensated for evaporation of droplets. The circulation processes mentioned above provide an efficient flame-holdingmechanism to stabilize the flame.Comparisons with results froma shorter length of cavity (cavity length of 45mm) show that, due to insufficient atomization and evaporation of the droplets in the short distance inside the cavity, parts of the droplets are carried out of the cavity through theboundary layer fluctuation and evaporated in the hot flame layer, thus resulting in incomplete air fuel mixing and worse combustion performance. The flow structures inside the cavity play an important role in the spray istribution, thus determining the combustion performance