497 research outputs found
Unity and Language
This 1952 study is an investigation into the nature of language that focuses on reinterpreting Hamann's theories of language in light of twentieth century linguistic philosophy. One of the first studies of Hamann to be presented in English, it poses many questions of universal concern and interest
Unity and Language: A Study in the Philosophy of Johann Georg Hamann
This 1952 study is an investigation into the nature of language that focuses on reinterpreting Hamann's theories of language in light of twentieth century linguistic philosophy. One of the first studies of Hamann to be presented in English, it poses many questions of universal concern and interest
Studies in Nietzsche and the Judaeo-Christian Tradition
This collection of essays is a sequel to the editors' 1976 volume "Studies in Nietzsche and the Classical Tradition". Philosophers, theologians, and literary historians discuss important aspects of Nietzsche's attack on Judaism and Christianity. The book contains studies of his view of biblical figures, Luther and Pascal as well as comparisons of his thought with that of Spinoza, Lessing, Heine, and Kierkegaard. Nietzsche's critique of the Old Testament, the Jewish religion of the diaspora, and historical Christianity are also investigated. Of the eighteen articles included here, thirteen were prepared expressly for this volumeâfive were translated from German, one from French, and one from Hebrew.
Contributors to this volume are: Eugen Biser, Harry Neumann, Israel Eldad, Charles Lewis, Jorg Salaquarda, Joan Stambaugh, Max L. Baeumer, Brendan Donellan, Diana Behler, Sander L. Gilman, Gerd-Gunther Grau, Josef Simon, James C. O'Flaherty, Bernd Magnus, Georges Goedert, Hans Lung, and Karl Barth
Potential benefits of healthy food and lifestyle policies for reducing coronary heart disease mortality in Turkish adults by 2025: a modelling study
Objective This study uses a modelling approach to compare the potential impact of future risk factor scenarios relating to smoking, physical activity levels, dietary salt, saturated fat intake, mean body mass index (BMI) levels, diabetes prevalence and fruit and vegetable (F&V) consumption on future coronary heart disease (CHD) mortality in Turkey for year 2025.
Design A CHD mortality model previously developed and validated in Turkey was extended to predict potential trends in CHD mortality from 2008 to 2025.
Setting Using risk factor trends data from recent surveys as a baseline, we modelled alternative evidence-based future risk factor scenarios (modest/ideal scenarios). Probabilistic sensitivity analyses were conducted to account for uncertainties.
Subject Projected populations in 2025 (aged 25â84) of 54 million in Turkey.
Results Assuming lower mortality, modest policy changes in risk factors would result in âŒ25â
635 (range: 20â
290â31â
125) fewer CHD deaths in the year 2025; 35.6% attributed to reductions in salt consumption, 20.9% to falls in diabetes, 14.6% to declines in saturated fat intake and 13.6% to increase in F&V intake. In the ideal scenario, 45â
950 (range: 36â
780â55â
450) CHD deaths could be prevented in 2025. Again, 33.2% of this would be attributed to reductions in salt reduction, 19.8% to increases in F&V intake, 16.7% to reductions in saturated fat intake and 14.0% to the fall in diabetes prevalence.
Conclusions Only modest risk factor changes in salt, saturated/unsaturated fats and F&V intake could prevent around 16â
000 CHD deaths in the year 2025 in Turkey, even assuming mortality continues to decline. Implementation of population-based, multisectoral interventions to reduce salt and saturated fat consumption and increase F&V consumption should be scaled up in Turkey
Resource recovery from the anaerobic digestion of food waste is underpinned by cross-kingdom microbial activities
This work was supported by the Earth and Natural Sciences (ENS) Doctoral Studies Programme, funded by the Higher Education Authority (HEA) of Ireland through the Programme for Research at Third Level Institutions, Cycle 5 (PRTLI-5), co-funded by the European Regional Development Fund (ERDF).As the human population grows on the planet so does the generation of waste and particularly that of food waste. In order to tackle the world sustainability crisis, efforts to recover products from waste are critical. Here, we anaerobically recovered volatile fatty acids (VFAs) from food waste and analysed the microbial populations underpinning the process. An increased contribution of fungi relative to bacteria was observed throughout the reactor operation, with both kingdoms implicated into the main three steps of anaerobic digestion occurring within our systems: hydrolysis, acidogenesis and acetogenesis. Overall, Ascomycota, Proteobacteria and Firmicutes were found to drive the anaerobic digestion of food waste, with butyrate as the most abundant VFA likely produced by Clostridium using lactate as a precursor. Taken together we demonstrate that the generation of products of added-value from food waste results from cross-kingdoms microbial activities implicating fungi and bacteria.Publisher PDFPeer reviewe
Multinet : enabler for next generation enterprise wireless services
Wireless communications are currently experiencing a fast migration toward the beyond third-generation (B3G)/fourth generation (4G) era. This represents a generational change in wireless systems: new capabilities related to mobility and new services support is required and new concepts as individual-centric, user-centric or ambient-aware communications are included. One of the main restrictions associated to wireless technology is mobility management, this feature was not considered in the design phase; for this reason, a complete solution is not already found, although different solutions are proposed and are being proposed. In MULTINET project, features as mobility and multihoming are applied to wireless network to provide the necessary network and application functionality enhancements for seamless data communication mobility considering end-user scenario and preferences. The aim of this paper is to show the benefits of these functionalities from the Service Providers and final User point of view
Novel translocation responses of cytosolic phospholipase A2α fluorescent proteins
AbstractCytosolic phospholipase A2 (cPLA2)α responds to the rise in cytosolic Ca2+ ([Ca2+]i) attending cell stimulation by moving to intracellular membranes, releasing arachidonic acid (AA) from these membranes, and thereby initiating the synthesis of various lipid mediators. Under some conditions, however, cPLA2α translocation occurs without any corresponding changes in [Ca2+]i. The signal for such responses has not been identified. Using confocal microscopy to track fluorescent proteins fused to cPLA2α or cPLA2α's C2 domain, we find that AA mimics Ca2+ ionophores in stimulating cPLA2α translocations to the perinuclear ER and to a novel site, the lipid body. Unlike the ionophores, AA acted independently of [Ca2+]i rises and did not translocate the proteins to the Golgi. AA's action did not involve its metabolism to eicosanoids or acylation into cellular lipids. Receptor agonists also stimulated translocations targeting lipid bodies. We propose that AA is a signal for Ca2+-independent cPLA2α translocation and that lipid bodies are common targets of cPLA2α and contributors to stimulus-induced lipid mediator synthesis
XMM-Newton observations of GB B1428+4217: confirmation of intrinsic soft X-ray absorption
We report the results of XMM-Newton observations of the X-ray bright,
radio-loud blazar GB B1428+4217 at a redshift of z=4.72. We confirm the
presence of soft X-ray spectral flattening at energies <0.7 keV as reported in
previous ROSAT and BeppoSAX observations. At hard X-ray energies the spectrum
is consistent with a power-law although we find the spectral slope varied
between both XMM-Newton observations and is also significantly different from
that reported previously. Whilst we cannot rule-out intrinsic cold absorption
to explain the spectral depression, we favour a dust-free warm absorber. Cold
absorption requires a column density ~1.4-1.6 x 10^22 cm^-2 whilst a warm
absorber could have up to ~10^23 cm^-2 and an ionization parameter ~10^2. The
spectrum of GB B1428+4217 shows remarkable parallels with that of the z=4.4
blazar PMN J0525-3343, in which the available evidence is also most consistent
with a warm absorber model.Comment: 5 pages, 5 figures, MNRAS accepted. Minor changes to sections 3.1 and
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