The School Improvement Partnership Programme: Using Collaboration and Enquiry to tackle Educational Inequity

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A feasibility study of signed consent for the collection of patient identifiable information for a national paediatric clinical audit database

Objectives: To investigate the feasibility of obtaining signed consent for submission of patient identifiable data to a national clinical audit database and to identify factors influencing the consent process and its success. Design: Feasibility study. Setting: Seven paediatric intensive care units in England. Participants: Parents/guardians of patients, or patients aged 12-16 years old, approached consecutively over three months for signed consent for submission of patient identifiable data to the national clinical audit database the Paediatric Intensive Care Audit Network (PICANet). Main outcome measures: The numbers and proportions of admissions for which signed consent was given, refused, or not obtained (form not returned or form partially completed but not signed), by age, sex, level of deprivation, ethnicity (South Asian or not), paediatric index of mortality score, length of hospital stay (days in paediatric intensive care). Results: One unit did not start and one did not fully implement the protocol, so analysis excluded these two units. Consent was obtained for 182 of 422 admissions (43%) (range by unit 9% to 84%). Most (101/182; 55%) consents were taken by staff nurses. One refusal (0.2%) was received. Consent rates were significantly better for children who were more severely ill on admission and for hospital stays of six days or more, and significantly poorer for children aged 10-14 years. Long hospital stays and children aged 10-14 years remained significant in a stepwise regression model of the factors that were significant in the univariate model. Conclusion: Systematically obtaining individual signed consent for sharing patient identifiable information with an externally located clinical audit database is difficult. Obtaining such consent is unlikely to be successful unless additional resources are specifically allocated to training, staff time, and administrative support

Hot Accretion With Conduction: Spontaneous Thermal Outflows

Motivated by the low-collisionality of gas accreted onto black holes in Sgr A* and other nearby galactic nuclei, we study a family of 2D advective accretion solutions with thermal conduction. While we only impose global inflow, the accretion flow spontaneously develops bipolar outflows. The role of conduction is key in providing the extra degree of freedom (latitudinal energy transport) necessary to launch these rotating thermal outflows. The sign of the Bernoulli constant does not discriminate between inflowing and outflowing regions. Our parameter survey covers mass outflow rates from ~ 0 to 13% of the net inflow rate, outflow velocities from ~0 to 11% of the local Keplerian velocity and outflow opening angles from ~ 0 to 60 degs. As the magnitude of conduction is increased, outflows can adopt a conical geometry, pure inflow solutions emerge, and the limit of 2D non-rotating Bondi-like solutions is eventually reached. These results confirm that radiatively-inefficient, hot accretion flows have a hydrodynamical propensity to generate bipolar thermal outflows.Comment: 38 pages, 10 figures, accepted for publication in Ap

A Note on the Slim Accretion Disk Model

We show that when the gravitational force is correctly calculated in dealing with the vertical hydrostatic equilibrium of black hole accretion disks, the relationship that is valid for geometrically thin disks, i.e., $c_s/\Omega_K H =$ constant, where $c_s$ is the sound speed, $\Omega_K$ is the Keplerian angular velocity, and $H$ is the half-thickness of the disk, does not hold for slim disks. More importantly, by adopting the correct vertical gravitational force in studies of thermal equilibrium solutions, we find that there exists a maximally possible accretion rate for each radius in the outer region of optically thick accretion flows, so that only the inner region of these flows can possibly take the form of slim disks, and strong outflows from the outer region are required to reduce the accretion rate in order for slim disks to be realized.Comment: 14 pages, 5 figures, accepted by Ap

Predicting Malawian women’s intention to adhere to antiretroviral therapy

Background. With the increase in scaling up of antiretroviral therapy (ART), knowledge of the need for adherence to ART is pivotal for successful treatment outcomes. Design and Methods. A cross-sectional study was carried out between October and December 2013. We administered theory of planned behaviour (TPB) and adherence questionnaires to 358 women aged 18-49 years, from a rural and urban ART-clinics in southern Malawi. Hierarchical linear regression models were used to predict intentions to adhere to ART. Results. Regression models showed that attitude (β=0.47), subjective norm (β=0.31), and perceived behavioral control (β=0.12) explain 55% of the variance in intentions to adhere to ART. The relationship between both food insecurity and perceived side effects with intentions to adhere to ART is mediated by attitude, subjective norm, and perceived behavioural control. Household (r=0.20) and individual (r=0.21) food insecurity were positively and significantly correlated with perceived behavioural control. Household food insecurity had a negative correlation with perceived side effects (r=-0.11). Perceived side effects were positively correlated with attitude (r=0.25). There was no statistically significant relationship between intentions to adhere to ART in the future and one month self-report of past month adherence. These interactions suggest that attitude predicted adherence only when food insecurity is high or perception of side effects is strong.Conclusions. This study shows that modification might be needed when using TPB constructs in resource constraint environment

Numerical Models of Viscous Accretion Flows Near Black Holes

We report on a numerical study of viscous fluid accretion onto a black hole. The flow is axisymmetric and uses a pseudo-Newtonian potential to model relativistic effects near the event horizon. The numerical method is a variant of the ZEUS code. As a test of our numerical scheme, we are able to reproduce results from earlier, similar work by Igumenshchev and Abramowicz and Stone et al. We consider models in which mass is injected onto the grid as well as models in which an initial equilibrium torus is accreted. In each model we measure three ``eigenvalues'' of the flow: the accretion rate of mass, angular momentum, and energy. We find that the eigenvalues are sensitive to r_{in}, the location of the inner radial boundary. Only when the flow is always supersonic on the inner boundary are the eigenvalues insensitive to small changes in r_{in}. We also report on the sensitivity of the results to other numerical parameters.Comment: 14 pages, 4 figures, 2 tables, to appear in v573 n2 pt1 ApJ July 10, 200

Inferring hidden Markov models from noisy time sequences: a method to alleviate degeneracy in molecular dynamics

We present a new method for inferring hidden Markov models from noisy time sequences without the necessity of assuming a model architecture, thus allowing for the detection of degenerate states. This is based on the statistical prediction techniques developed by Crutchfield et al., and generates so called causal state models, equivalent to hidden Markov models. This method is applicable to any continuous data which clusters around discrete values and exhibits multiple transitions between these values such as tethered particle motion data or Fluorescence Resonance Energy Transfer (FRET) spectra. The algorithms developed have been shown to perform well on simulated data, demonstrating the ability to recover the model used to generate the data under high noise, sparse data conditions and the ability to infer the existence of degenerate states. They have also been applied to new experimental FRET data of Holliday Junction dynamics, extracting the expected two state model and providing values for the transition rates in good agreement with previous results and with results obtained using existing maximum likelihood based methods.Comment: 19 pages, 9 figure

Symmetry-breaking and chaos in electron transport in semiconductor superlattices

We study the motion of electrons in a single miniband of a semiconductor superlattice driven by THz electric field polarized along the growth direction. We work in the semiclassical balance-equation model, including different elastic and inelastic scattering rates, and incorporating the self-consistent electric field generated by electron motion. We explore regions of complex dynamics, which can include chaotic behaviour and symmetry-breaking. We estimate the magnitudes of dc current and dc voltage that spontaneously appear in regions of broken-symmetry for parameters characteristic of modern semiconductor superlattices. This work complements PRL 80(1998)2669 [ cond-mat/9709026 ].Comment: 4 pages, 3 figures, RevTEX, EPS

A PC parallel port button box provides millisecond response time accuracy under Linux

For psychologists, it is sometimes necessary to measure people's reaction times to the nearest millisecond. This article describes how to use the PC parallel port to receive signals from a button box to achieve millisecond response time accuracy. The workings of the parallel port, the corresponding port addresses, and a simple Linux program for controlling the port are described. A test of the speed and reliability of button box signal detection is reported. If the reader is moderately familiar with Linux, this article should provide sufficient instruction for him or her to build and test his or her own parallel port button box. This article also describes how the parallel port could be used to control an external apparatus