3,826 research outputs found

    Trade Liberalizing Impacts of NAFTA in Sugar: Global Implications

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    policy, NAFTA, sugar, International Relations/Trade, Q18,

    The Affective Impact of Financial Skewness on Neural Activity and Choice

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    Few finance theories consider the influence of “skewness” (or large and asymmetric but unlikely outcomes) on financial choice. We investigated the impact of skewed gambles on subjects' neural activity, self-reported affective responses, and subsequent preferences using functional magnetic resonance imaging (FMRI). Neurally, skewed gambles elicited more anterior insula activation than symmetric gambles equated for expected value and variance, and positively skewed gambles also specifically elicited more nucleus accumbens (NAcc) activation than negatively skewed gambles. Affectively, positively skewed gambles elicited more positive arousal and negatively skewed gambles elicited more negative arousal than symmetric gambles equated for expected value and variance. Subjects also preferred positively skewed gambles more, but negatively skewed gambles less than symmetric gambles of equal expected value. Individual differences in both NAcc activity and positive arousal predicted preferences for positively skewed gambles. These findings support an anticipatory affect account in which statistical properties of gambles—including skewness—can influence neural activity, affective responses, and ultimately, choice

    Evaluation of a proton pencil bean algorithm for dose calculations in heterogenous media

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    Purpose: To develop an improved nuclear halo dose model of a pencil beam algorithm (PBA) for dose calculation of proton beams in heterogeneous media. Methods: The proton PBA consisted of a central axis term and an off axis term. The central axis term was determined from a central axis depth dose profile of a Monte Carlo simulated proton beam in water and was scaled by a mass stopping power ratio to account for other materials. The off axis term was determined from Fermi-Eyges scattering theory with material-dependent scattering powers to calculate the lateral spread of the proton beam in heterogeneous media. The nuclear halo dose, which was caused by large angle and non-elastic scattering events, was modeled using two terms: a Gaussian distribution and a Cauchy-Lorentz distribution. Depth-dependent widths and amplitudes of each distribution were determined by fitting a simulated 1-mm x 1-mm pencil beam in water. The PBA was evaluated in approximately 30 test phantoms containing bone and/or air heterogeneities at 4 energies and for 2 field sizes. Agreement between PBA and Monte Carlo simulations of the test conditions was quantified by computing the percentage of points within 2 percent dose difference or 1 mm distance to agreement. Results: With the improved nuclear halo model, PBA calculations showed better than of 97% of dose points within 2% or 1 mm of MC distributions for all geometries examined. For phantoms containing laterally infinite heterogeneities, agreement between PBA and MC distributions was 100% at 2% or 1mm. For phantoms containing laterally finite heterogeneities, agreement was at least 97%. The points failing were due to the central axis approximation of the PBA in regions not influenced by the nuclear halo model. Conclusions: The nuclear halo model developed in this work improves the agreement of the PBA with MC simulations in heterogeneous phantoms, particularly in low-dose regions that can be important for scanned-beam proton therapy

    Double Schubert polynomials for the classical groups

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    For each infinite series of the classical Lie groups of type B,C or D, we introduce a family of polynomials parametrized by the elements of the corresponding Weyl group of infinite rank. These polynomials represent the Schubert classes in the equivariant cohomology of the appropriate flag variety. They satisfy a stability property, and are a natural extension of the (single) Schubert polynomials of Billey and Haiman, which represent non-equivariant Schubert classes. They are also positive in a certain sense, and when indexed by maximal Grassmannian elements, or by the longest element in a finite Weyl group, these polynomials can be expressed in terms of the factorial analogues of Schur's Q- or P-functions defined earlier by Ivanov.Comment: 41 pages, 2 tables; comments welcom

    XMM-Newton observations of HD189733 during planetary transits

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    We report on two XMM-Newton observations of the planetary host star HD189733. The system has a close in planet and it can potentially affect the coronal structure via interactions with the magnetosphere. We have obtained X-ray spectra and light curves from EPIC and RGS on board XMM-Newton which we have analyzed and interpreted. We reduced X-ray data from primary transit and secondary eclipse occurred in April 17th 2007 and May 18th 2009, respectively. In the April 2007 observation only variability due to weak flares is recognized. In 2009 HD189733 exhibited a X-ray flux always larger than in the 2007 observation. The average flux in 2009 was higher than in 2007 observation by a factor of 45%. During the 2009 secondary eclipse we observed a softening of the X-ray spectrum significant at level of ~3 sigma. Further, we observed the most intense flare recorded at either epochs. This flare occurred 3 ks after the end of the eclipse.The flare decay shows several minor ignitions perhaps linked to the main event and hinting for secondary loops that emit triggered by the main loop. Magneto-Hydro-Dynamical (MHD) simulations show that the magnetic interaction between planet and star enhances the density and the magnetic field in a region comprised between the planet and the star because of their relative orbital/rotation motion. X-ray observations and model predictions are globally found in agreement, despite the quite simple MHD model and the lack of precise estimate of parameters including the alignment and the intensity of stellar and planetary magnetic fields. Future observations should confirm or disprove this hypothesis, by determining whether flares are systematically recurring in the light curve at the same planetary phase.Comment: Accepted for publication on The Astrophysical Journa

    HST Spectrophotometry and Models for Solar Analogs

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    Absolute flux distributions for seven solar analog stars are measured from 0.3 to 2.5 \mu m by HST spectrophotometry.In order to predict the longer wavelength mid-IR fluxes that are required for JWST calibration, the HST SEDs are fit with Castelli & Kurucz model atmospheres; and the results are compared with fits from the MARCS model grid. The rms residuals in 10 broad band bins are all <0.5% for the best fits from both model grids. However, the fits differ systematically: The MARCS fits are 40-100 K hotter in T_{eff}, 0.25-0.80 higher in log g, 0.01-0.10 higher in log z, and 0.008-0.021 higher in the reddening E(B-V), probably because their specifications include different metal abundances. Despite these differences in the parameters of the fits, the predicted mid-IR fluxes differ by only ~1%; and the modeled flux distributions of these G stars have an estimated ensemble accuracy of 2% out to 30 \mu m.Comment: 19 pages, 2 tables, 7 figures; to appear in AJ 2010 Apri

    Histologic Changes Produced by 2,3,7,8-Tetrachlorodibenzo-p-dioxin in the Skin of Mice Carrying Mutations That Affect the Integument

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    2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) produces epidermal hyperplasia and hyperkeratosis, squamous metaplasia of the sebaceous gland, and keratinized cyst formation in 8 strains of mice with the recessive mutation, hairless (hr/hr). The extent of these histologic changes is dependent on the genetic background. No cutaneous lesions are produced in haired (hr/+) mice. In examination of mice with 7 other mutations affecting the integument, TCDD produced similar histologic skin changes in cryptothrix, nude, plucked, and atrichosis; a marginal squamous metaplasia of sebaceous glands in Repeated epilation, and had no effect in fur deficient and Naked mutants. These genetically determined epidermal responses are discussed in light of the mechanism of action of TCDD

    Portal dosimetry scripting application programming interface (PDSAPI) for Winston-Lutz test employing ceramic balls

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    PURPOSE: Stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) treatments require a high degree of accuracy. Mechanical, imaging, and radiation isocenter coincidence is especially important. As a common method, the Winston-Lutz (WL) test plays an important role. However, weekly or daily WL test can be very time consuming. We developed novel methods using Portal Dosimetry Scripting Application Programming Interface (PDSAPI) to facilitate the test as well as documentation. METHODS: Winston-Lutz PDSAPI was developed and tested on our routine weekly WL imaging. The results were compared against two commercially available software RIT (Radiological Imaging Technology, Colorado Springs, CO) and DoseLab (Varian Medical Systems, Inc. Palo Alto, CA). Two manual methods that served as ground truth were used to verify PDSAPI results. Twenty WL test image data sets (10 fields per tests, and 200 images in total) were analyzed by these five methods in this report. RESULTS: More than 99.5% of WL PDSAPI 1D shifts agreed with each of four other methods within ±0.33 mm, which is roughly the pixel width of a-Si 1200 portal imager when source to imager distance (SID) is at 100 cm. 1D shifts agreement for ±0.22 mm and 0.11 mm were 96% and 63%, respectively. Same trend was observed for 2D displacement. CONCLUSIONS: Winston-Lutz PDSAPI delivers similar accuracy as two commercial applications for WL test. This new application can save time spent transferring data and has the potential to implement daily WL test with reasonable test time. It also provides the data storage capability, and enables easy access to imaging and shift data
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