368 research outputs found

    Lawyers in the Shadow of the Regulatory State: Transnational Governance on Business and Human Rights

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    Lawyers are beginning to play an important role in strengthening the system of transnational governance that regulates business and human rights. In setting the background to our discussion of lawyers’ role in this context, Part I of this Article provides a general overview of the emergence of the transnational governance regime. Part II then describes some of the governance instruments that attempt to prevent and rectify the adverse human rights impacts of business activities. Part III discusses the extent to which lawyers are advising their business clients on human rights issues, the factors that may inhibit or encourage the provision of such advice, and how the lawyers who are raising these issues are framing these discussions with their clients. Finally, Part IV suggests further areas of inquiry that may enrich our understanding of the role that lawyers can play in helping construct a transnational governance regime on business and human rights

    A serological investigation of caseous lymphadenitis in four flocks of sheep

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    A double antibody sandwich ELISA developed by ID-DLO, Lelystad to detect Corynebocterium pseudotuberculosis infection was used on 329 sheep from four pedigree Suffolk flocks in which clinical cases of caseous lymphadenitis (CLA) had occurred. At subsequent necropsy, typical CLA lesions were seen in 133 sheep, and the diagnosis was confirmed on culture. Lesions were most commonly seen in lungs (n = 46), parotid lymph nodes (n = 44), prescapular lymph nodes (n = 38) and mediastinal lymph nodes (n = 31). The sensitivity of the ELISA test for detecting culture-positive sheep was 0.88, while the specificity of the test was 0.55. The antibody ELISA detected 87.5 per cent of sheep that had CLA lesions restricted to internal organs only. It was concluded that the ELISA test has a valuable role in detecting sheep with both clinical and subclinical CLA

    FLEX to evidence Good Standing

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    Copula-based agricultural conditional value-at-risk modelling for geographical diversifications in wheat farming portfolio management

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    An agricultural producer's crop yield and subsequent farming revenues are affected by many complex factors, including price fluctuations, government policy and climate (e.g., rainfall and temperature) extremes. Geographical diversification is identified as a potential farmer adaptation and decision support tool that could assist producers to reduce unfavourable financial impacts due to variabilities in crop price and yield, associated with climate variations. There has been limited research performed on the effectiveness of this strategy. The paper proposed a new statistical approach to investigate whether the geographical spread of wheat farm portfolios across three climate broad-acre (i.e., rain-fed) zones could potentially reduce financial risks for producers in Australian agro-ecological zones. A suite of popular and statistically robust tools applied in finance based on well-established statistical theories, comprised of the Conditional Value-at-Risk (CVaR) and the joint copula model were employed to evaluate the effectiveness geographical diversification. CVaR is utilised to benchmark the loss (i.e., downside risk), while the copula function is employed to model joint distribution among marginal returns (i.e., profit in each zone). The mean-CVaR optimisations indicate that geographical diversification could be a feasible agricultural risk management approach for wheat farm portfolio managers in achieving their optimised expected returns while controlling the risks (i.e., targeting levels of risk). Further, in this study, the copula-based mean-CVaR model is seen to better simulate extreme losses compared to the conventional multivariate-normal models, which underestimate the minimum risk levels at a given target of expected return. Among the suite of tested copula-based models, the vine copula in this study is found to be a superior in capturing the tail dependencies compared to the other multivariate copula models investigated

    tert-Butyl 4-(1-methyl-1H-pyrazol-5-yl)piperidine-1-carboxyl­ate

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    The reaction of (E)-tert-butyl 4-[3-(dimethyl­amino)acrylo­yl]piperidine-1-carboxyl­ate with methyl­hydrazine leads to the formation of the title compound, C14H23N3O2, with a 1-methyl-1H-pyrazol-5-yl substituent. The plane of the pyrazole ring forms a dihedral angle of 33.4 (1)° with the approximate mirror plane of the piperidine ring

    Conservation Guidance for Indiana Bat (Myotis sodalis)

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    Illinois Natural History Survey has undertaken a project producing documents that provide conservation guidance for listed species in Illinois for the Illinois Department of Natural Resources. The project is titled: Conservation Guidance for Species in Greatest Need of Conservation (SGNC) T- 96-R-001. The primary purpose of guidance documents is to provide various project developers/land managers with information on the species, how their actions may impact the species, and how they can minimize/mitigate/monitor those impacts. In addition, the documents may be useful for identifying research needs to direct various funds, as a first step towards recovery planning, or for informing the general public. We intend the documents to be comprehensive and inclusive of scientific and experiential knowledge of the species and its conservation. The documents incorporate information on current conservation efforts, conservation opportunities and research needs.Interviews with stakeholders were held to identify information that should be included in conservation guidance documents. We prioritized document production for species that were frequently the subject of Incidental Take Authorizations or were consulted on in the IDNR’s EcoCat program. Initial literature reviews was conducted to produce first draft documents. Then a list of potential document reviewers, including academic taxa experts, conservation organizations, private consultants, and government agency staff, was compiled for each species. The documents underwent review and revision. What follows is the final document providing conservation guidance for Indiana bat, which was reviewed by 7 individuals.Illinois Department of Natural Resources, State Wildlife Initiative Grants Programunpublishednot peer reviewedOpe

    5-Bromo-3-(indan-1-yl­oxy)pyridin-2-amine

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    The title compound, C14H13BrN2O, was obtained by reaction of indan-1-yl methane­sulfonate with 2-amino-5-bromo­pyridin-3-ol in the presence of caesium carbonate. The indane ring system is approximately planar [all but one of the C atoms are coplanar within 0.03 Å, the latter atom being displaced by 0.206 (2) Å from the mean plane through the remaining atoms] and forms a dihedral angle of 58.41 (4)° with the pyridine ring. In the crystal, centrosymmetrically related mol­ecules are linked into dimers by N—H⋯N hydrogen bonds

    5-Chloro-N-[2-(1H-imidazol-4-yl)eth­yl]-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

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    The title compound, C12H13ClN6, was prepared by reaction of 4,5-dichloro-7H-pyrrolo[2,3-d]pyrimidine with 2-(1H-imid­azol-4-yl)-N-methyl­ethanamine, and the X-ray study confirmed that chloro-substituent in six-membered ring was replaced in the reaction. The exocyclic N atom environment is approximately coplanar with the pyrrolo[2,3-d]pyrimidine [corresponding dihedral angle is 5.5 (1)°], whereas the mean plane of the N—C—C—C link connecting with the imidazolyl ring is almost exactly orthogonal to the plane of the bicyclic system [dihedral angle = 91.6 (2)°]. The imidazolyl plane itself, however, forms a relatively small dihedral angle of 20.8 (1)° with the pyrrolo[2,3-d]pyrimidine plane. There are two independent N—H⋯N hydrogen bonds in the structure, which link mol­ecules into layers parallel to (03)
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