1,417 research outputs found

    The Theory of Fuzzy Logic and its Application to Real Estate Valuation

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    Fuzzy logic is based on the central idea that in fuzzy sets each element in the set can assume a value from 0 to 1, not just 0 or 1, as in classic set theory. Thus, qualitative characteristics and numerically scaled measures can exhibit gradations in the extent to which they belong to the relevant sets for evaluation. This degree of membership of each element is a measure of the element’s "belonging" to the set, and thus of the precision with which it explains the phenomenon being evaluated. Fuzzy sets can be combined to produce meaningful conclusions, and inferences can be made, given a specified fuzzy input function. The article demonstrates the application of fuzzy logic to an income-producing property, with a resulting fuzzy set output.

    A Leafhopper Pest of Plants in the Mint Family, Eupteryx decemnotata Rey (Hemiptera: Auchenorrhyncha: Cicadellidae), Ligurian Leafhopper, New to North America

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    The Ligurian leafhoppter, Eupteryx decemnotata Rey (Hemiptera: Auchenorrhyncha: Cicadellidae), is reported for the first time in North America (USA: Florida and California). Diagnostic characters for species identification, summary of hosts and damage, and U.S. known distribution are given

    Preparation and characterisation of free flowing solid lipid based drug delivery systems using a twin screw extruder

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    In this study, a continuous manufacturing process was developed for adsorbing liquid self-emulsifying drug delivery system (SEDDS) on mesoporous silica carriers in order to produce solid free flowing SEDDS powders. An optimized liquid SEDDS, consisting of Labrafil M 1944 CS, Labrasol and Capryol 90 (15, 80, 5 %w/w), was developed. The formulation spontaneously formed a homogenous emulsion with a droplet size of less than 200 nm (in water) and possessed pH robustness (pH 1.2, pH 6.8). Two grades of mesoporous silica were investigated as solid carriers, namely Syloid XDP 3050 and 3150. A twin screw extruder, setup in the granulation configuration, was employed to assess the mixing and adsorption of liquid SEDDS onto silica particles in a continuous process. Screw configuration, ratio of solid carrier to liquid SEDDS, powder and liquid feed rates and screw speed were identified as important parameters. These parameters were tested and optimized to achieve free flowing solid SEDDS. The maximum lipid loading of Syloid XDP 3050 and 3150 was 1:2 and 1:2 to less than 1:3 ratios, respectively. Although increasing liquid SEDDS loading increased the cohesive properties of the silica particles, the resulting powders afforded acceptable flow rate indexes as determined by powder rheometry. Similar self-emulsification behaviour was observed for solid and liquid SEDDS. With increasing lipid loading, the droplet size of emulsified solid SEDDS increased and changed from a unimodal to a bimodal size distributions. This effect was more pronounced for Syloid XDP3050. Syloid XDP 3150 was less sensitive to droplet size changes as its z-average diameters at 1:2-1:3 ratio were similar to the optimized liquid SEDDS. Targeting a lipid loading ratio of 2:1, process parameters were varied to maximise material throughput. The investigated continuous process of adsorbing liquid SEDDs onto solid carriers produced solid SEDDS with good flow properties. Syloid XDP 3150 seemed more robust to the process than Syloid XDP 3050

    Home versus day rehabilitation: a randomised controlled trial

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    Objective: to assess the effect of home versus day rehabilitation on patient outcomes

    Inconsistencies in Appraisal Theory and Practice

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    This paper points out some inconsistencies in appraisal practice stemming, in some cases, from inconsistencies in underlying theory, and in some cases from applications that are inconsistent with theory. The identification of inconsistencies in appraisal practice is not meant to be a wholesale attack on traditional appraisal approaches. Quite the contrary; the inconsistencies are identified with the premise that their correction would strengthen these procedures. The corollary is, of course, that their continued occurrences weaken appraisal and the appraisal function. They may lead to inaccurate value conclusions, disparities among appraisals, and lowered public confidence in appraisers. Most of the alleged inconsistencies cited in this paper can be easily corrected intellectually. Indeed, some already have been, and the corrections are slowly filtering into practice.

    Microfactory – Blend – Compression - Performance test

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    Aims and objectives - API’s with acicular habits are commonplace and present processing and handling challenges due to poor flow. This is traditionally addressed by wet granulation processes during formulation. Currently continuous direct compression (CDC) is gaining favour as a simplified formulation and dose formation process. However, poor flow properties limit CDC. This work aims to enable CDC by spherical agglomeration in the primary process and develop underpinning modelling approaches to allow formulations to be explored in-silico (i.e. digital twin) - Here at CMAC an integrated crystalisation-spherical agglomeration-drying-blending-compression process is being developed (microfactory) to be used to parameterise and develop modelling tools on the g-formulate package - This work presents some of the activities on the compression component to parameterise and develop a suitable model to enable the process to be explored (i.e. digital twin

    Plus Factors and Agreement in Antitrust Law

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    Plus factors are economic actions and outcomes, above and beyond parallel conduct by oligopolistic firms, that are largely inconsistent with unilateral conduct but largely consistent with explicitly coordinated action. Possible plus factors are typically enumerated without any attempt to distinguish them in terms of a meaningful economic categorization or in terms of their probative strength for inferring collusion. In this Article, we provide a taxonomy for plus factors as well as a methodology for ranking plus factors in terms of their strength for inferring explicit collusion, the strongest of which are referred to as super plus factors

    Plus Factors and Agreement in Antitrust Law

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    Plus factors are economic actions and outcomes, above and beyond parallel conduct by oligopolistic firms, that are largely inconsistent with unilateral conduct but largely consistent with explicitly coordinated action. Possible plus factors are typically enumerated without any attempt to distinguish them in terms of a meaningful economic categorization or in terms of their probative strength for inferring collusion. In this Article, we provide a taxonomy for plus factors as well as a methodology for ranking plus factors in terms of their strength for inferring explicit collusion, the strongest of which are referred to as super plus factors

    Information scraps: how and why information eludes our personal information management tools

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    In this paper we describe information scraps -- a class of personal information whose content is scribbled on Post-it notes, scrawled on corners of random sheets of paper, buried inside the bodies of e-mail messages sent to ourselves, or typed haphazardly into text files. Information scraps hold our great ideas, sketches, notes, reminders, driving directions, and even our poetry. We define information scraps to be the body of personal information that is held outside of its natural or We have much still to learn about these loose forms of information capture. Why are they so often held outside of our traditional PIM locations and instead on Post-its or in text files? Why must we sometimes go around our traditional PIM applications to hold on to our scraps, such as by e-mailing ourselves? What are information scraps' role in the larger space of personal information management, and what do they uniquely offer that we find so appealing? If these unorganized bits truly indicate the failure of our PIM tools, how might we begin to build better tools? We have pursued these questions by undertaking a study of 27 knowledge workers. In our findings we describe information scraps from several angles: their content, their location, and the factors that lead to their use, which we identify as ease of capture, flexibility of content and organization, and avilability at the time of need. We also consider the personal emotive responses around scrap management. We present a set of design considerations that we have derived from the analysis of our study results. We present our work on an application platform, jourknow, to test some of these design and usability findings
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