76 research outputs found

    The Indian Ocean tsunami: socio-economic impacts in Thailand

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    On the morning of 26 December 2004 large areas of coastal southern Thailand were transformed when a tsunami, generated by a powerful submarine earthquake in the Indian Ocean, swept ashore. Officially, there were 5395 confirmed deaths in Thailand with another 2932 people listed as missing. In February 2005 a team led by Dr Ben Horton of the University of Pennsylvania was awarded an SGER grant by the National Science Foundation to undertake exploratory research on the tsunami in Malaysia and Thailand. This report summarizes the preliminary conclusions of the social science element of the Thai fieldwork. The team undertook fieldwork in three main sites during July 2005: Koh Lanta, Koh Phi Phi and Khao Lak. We chose Koh Phi Phi as a small, tourist (backpacker)-oriented island economy with high levels of damage and casualties; Koh Lanta as a site with a significant population of fisherfolk with a long presence in the area; and Khao Lak as a mainland site with the highest number of casualties in Thailand and with a mixed tourism-fishing economy

    Preliminary genetic evidence of two different populations of Opisthorchis viverrini in Lao PDR

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    Opisthorchis viverrini is a major public health concern in Southeast Asia. Various reports have suggested that this parasite may represent a species complex, with genetic structure in the region perhaps being dictated by geographical factors and different species of intermediate hosts. We used four microsatellite loci to analyze O. viverrini adult worms originating from six species of cyprinid fish in Thailand and Lao PDR. Two distinct O. viverrini populations were observed. In Ban Phai, Thailand, only one subgroup occurred, hosted by two different fish species. Both subgroups occurred in fish from That Luang, Lao PDR, but were represented to very different degrees among the fish hosts there. Our data suggest that, although geographical separation is more important than fish host specificity in influencing genetic structure, it is possible that two species of Opisthorchis, with little interbreeding, are present near Vientiane in Lao PDR

    Securitization and Community-Based Protection Among Chin Refugees in Kuala Lumpur

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    This article examines refugee-led community organizations among Chin refugees from Myanmar in Kuala Lumpur. It uses a structuration analysis that recognizes refugee-led organizations as complex governance entities engaged in a dynamic relationship with (among others) national policies of securitization of forced migration and international humanitarian governance. This approach expands the existing literature on the securitization of forced migration by exploring refugees’ lived experiences in a context of south–south migration. It expands the literature on community-based protection by going beyond recognizing the existence of refugee-led organizations to analyse their construction, constitution and consequences. Three primary areas of work by Chin refugee groups are analysed in relation to their immediate activity and longer term effects: organization (‘building ethnic unity in adversity’), documentation (‘asserting a bureaucratic identity’) and socialization (‘learning to be illegal’). These long-term effects indicate the possible impact of local protection activities on macrostructural processes such as identity construction and migration choices.construction, constitution and consequences. Three primary areas of work by Chin refugee groups are analysed in relation to their immediate activity and longer term effects: organization (‘building ethnic unity in adversity’), documentation (‘asserting a bureaucratic identity’) and socialization (‘learning to be illegal’). These long-term effects indicate the possible impact of local protection activities on macrostructural processes such as identity construction and migration choices

    Anti-cancer effects and mechanism of actions of aspirin analogues in the treatment of glioma cancer

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    INTRODUCTION: In the past 25 years only modest advancements in glioma treatment have been made, with patient prognosis and median survival time following diagnosis only increasing from 3 to 7 months. A substantial body of clinical and preclinical evidence has suggested a role for aspirin in the treatment of cancer with multiple mechanisms of action proposed including COX 2 inhibition, down regulation of EGFR expression, and NF-κB signaling affecting Bcl-2 expression. However, with serious side effects such as stroke and gastrointestinal bleeding, aspirin analogues with improved potency and side effect profiles are being developed. METHOD: Effects on cell viability following 24 hr incubation of four aspirin derivatives (PN508, 517, 526 and 529) were compared to cisplatin, aspirin and di-aspirin in four glioma cell lines (U87 MG, SVG P12, GOS – 3, and 1321N1), using the PrestoBlue assay, establishing IC50 and examining the time course of drug effects. RESULTS: All compounds were found to decrease cell viability in a concentration and time dependant manner. Significantly, the analogue PN517 (IC50 2mM) showed approximately a twofold increase in potency when compared to aspirin (3.7mM) and cisplatin (4.3mM) in U87 cells, with similar increased potency in SVG P12 cells. Other analogues demonstrated similar potency to aspirin and cisplatin. CONCLUSION: These results support the further development and characterization of novel NSAID derivatives for the treatment of glioma

    Lost in sovereign space: Forced migrants in the territorial trap

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    Asian and Pacific Migration Journal114437-46

    Pacific geographies and the politics of Buddhist peace activism

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    10.1016/j.polgeo.2011.04.007Political Geography304190-19

    Reflections on the relevance of classic approaches and contemporary priorities in boundary studies

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    10.1080/14650040500318548Geopolitics104650-662GEOP

    Political geographies of silence and erasure

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    10.1016/j.polgeo.2006.06.001Political Geography255479-48
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