Development of a bedrest muscle stress apparatus

In attempting further to define the deleterious effects of spaceflight on the human body, measurement systems and techniques were devised to determine the loss of skeletal muscle strength and tone as a result of spaceflight exposure. In order to determine how the muscle degradation process progresses with time during nonuse, a system for measuring muscle stress during bedrest was developed. The Bedrest Muscle Stress Apparatus is configured to slip snugly over the foot board of a standard hospital bed. Data collected with this device correlated well with pre- and post-bedrest data collected with the original skeletal muscle stress apparatus

Pseudomoduli Dark Matter

We point out that pseudomoduli -- tree-level flat directions that often accompany dynamical supersymmetry breaking -- can be natural candidates for TeV-scale dark matter in models of gauge mediation. The idea is general and can be applied to different dark matter scenarios, including (but not limited to) those of potential relevance to recent cosmic ray anomalies. We describe the requirements for a viable model of pseudomoduli dark matter, and we analyze two example models to illustrate the general mechanism -- one where the pseudomoduli carry Higgsino-like quantum numbers, and another where they are SM singlets but are charged under a hidden-sector $U(1)'$ gauge group.Comment: 20 pages, refs adde

Intraocular solitary extramedullary plasmacytoma presenting as unilateral anterior and intermediate uveitis preceded by refractory glaucoma

Background: Solitary extramedullary plasmacytoma (SEP) is a localised proliferation of monoclonal plasma cells involving soft tissue with no or minimal bone marrow involvement and no other systemic evidence of multiple myeloma. Intraocular involvement is exceedingly rare. Case presentation: We report a 78-year-old man who was referred with glaucoma in the right eye. He subsequently developed anterior chamber (AC) inflammation and refractory glaucoma then dense vitritis. A vitrectomy was performed with the biopsy revealing numerous plasma cells with atypical findings. In conjunction with the flow cytometry results, and a systemic work up excluding multiple myeloma, a diagnosis of SEP was made. The patient was treated with ocular external beam radiotherapy with resolution of the intraocular inflammation and control of the intraocular pressure. He remains well with no local recurrence and no development of multiple myeloma over a follow up period of 2.5 years. Conclusions: This is the first case report of SEP presenting as intraocular inflammation without a uveal tract mass

Wind-profiler observations of gravity waves produced by convection at mid-latitudes

This work presents a case study which includes regions of large rapidly varying vertical velocities observed by a VHF wind-profiler at Aberystwyth (52.4° N, 4.1° W). Analysis indicates that this region is associated with gravity waves above the tropopause level and simultaneous regions of convective activity below the tropopause level. This case study also suggests that convective activity can be identified effectively by finding periods of large uncertainties on the derived velocities. These regions are hypothesized to be related to regions of small-scale inhomogeneity in the wind field. Examination suggests that the large vertical velocity fluctuations above these convective regions are short period gravity wave packets as expected from theory. In addition the vertical flux of the horizontal momentum associated with the gravity waves also displays the pattern of reversal observed in previous studies

The Far-infrared Continuum of Quasars

ISO provides a key new far-infrared window through which to observe the multi-wavelength spectral energy distributions (SEDs) of quasars and active galactic nuclei (AGN). It allows us, for the first time, to observe a substantial fraction of the quasar population in the far-IR, and to obtain simultaneous, multi-wavelength observations from 5--200 microns. With these data we can study the behavior of the IR continuum in comparison with expectations from competing thermal and non-thermal models. A key to determining which mechanism dominates, is the measurement of the peak wavelength of the emission and the shape of the far-IR--mm turnover. Turnovers which are steeper than frequency^2.5 indicate thermal dust emission in the far-IR. Preliminary results from our ISO data show broad, fairly smooth, IR continuum emission with far-IR turnovers generally too steep to be explained by non-thermal synchrotron emission. Assuming thermal emission throughout leads to a wide inferred temperature range of 50-1000 K. The hotter material, often called the AGN component, probably originates in dust close to and heated by the central source, e.g. the ubiquitous molecular torus. The cooler emission is too strong to be due purely to cool, host galaxy dust, and so indicates either the presence of a starburst in addition to the AGN or AGN-heated dust covering a wider range of temperatures than present in the standard, optically thick torus models.Comment: 4 pages, to be published in the proceedings of "The Universe as Seen by ISO," ed. M. Kessler. This and related papers can be found at http://hea-www.harvard.edu/~ehooper/ISOkp/ISOkp.htm

Progress on the Low-Latency Inspiral Gravitational Wave Detection algorithm known as SPIIR

Low-latency event triggers to signify the presence of gravitational waves from coalescing binaries will be required to make prompt electromagnetic follow-up observations of electromagnetic counterparts. We present the recent progress made on implementing the time-domain low-latency detection algorithm known as summed parallel infinite impulse response (SPIIR) filtering into a real gravitational wave search pipeline

Prospects For Identifying Dark Matter With CoGeNT

It has previously been shown that the excess of events reported by the CoGeNT collaboration could be generated by elastically scattering dark matter particles with a mass of approximately 5-15 GeV. This mass range is very similar to that required to generate the annual modulation observed by DAMA/LIBRA and the gamma rays from the region surrounding the Galactic Center identified within the data of the Fermi Gamma Ray Space Telescope. To confidently conclude that CoGeNT's excess is the result of dark matter, however, further data will likely be needed. In this paper, we make projections for the first full year of CoGeNT data, and for its planned upgrade. Not only will this body of data more accurately constrain the spectrum of nuclear recoil events, and corresponding dark matter parameter space, but will also make it possible to identify seasonal variations in the rate. In particular, if the CoGeNT excess is the product of dark matter, then one year of CoGeNT data will likely reveal an annual modulation with a significance of 2-3$\sigma$. The planned CoGeNT upgrade will not only detect such an annual modulation with high significance, but will be capable of measuring the energy spectrum of the modulation amplitude. These measurements will be essential to irrefutably confirming a dark matter origin of these events.Comment: 6 pages, 6 figure

Infrared Properties of High Redshift and X-ray Selected AGN Samples

The NASA/ISO Key Project on active galactic nuclei (AGN) seeks to better understand the broad-band spectral energy distributions (SEDs) of these sources from radio to X-rays, with particular emphasis on infrared properties. The ISO sample includes a wide variety of AGN types and spans a large redshift range. Two subsamples are considered herein: 8 high-redshift (1 < z < 4.7) quasars; and 22 hard X-ray selected sources. The X-ray selected AGN show a wide range of IR continuum shapes, extending to cooler colors than the optical/radio sample of Elvis et al. (1994). Where a far-IR turnover is clearly observed, the slopes are < 2.5 in all but one case so that non-thermal emission remains a possibility. The highest redshift quasars show extremely strong, hot IR continua requiring ~ 100 solar masses of 500 - 1000 Kelvin dust with ~ 100 times weaker optical emission. Possible explanations for these unusual properties include: reflection of the optical light from material above/below a torus; strong obscuration of the optical continuum; or an intrinsic deficit of optical emission.Comment: 8 pages, 3 figures (2 color), to be published in the Springer Lecture Notes of Physics Series as part of the proceedings for "ISO Surveys of a Dusty Universe," a workshop held at Ringberg Castle, Germany, November 8 - 12, 1999. Requires latex style files for this series: cl2emult.cls, cropmark.sty, lnp.sty, sprmindx.sty, subeqnar.sty (included with submission

Z(2)-Singlino Dark Matter in a Portal-Like Extension of the Minimal Supersymmetric Standard Model.

We propose a Z2-stabilized singlino () as a dark matter candidate in extended and R-parity violating versions of the supersymmetric standard model. interacts with visible matter via a heavy messenger field S, which results in a supersymmetric version of the Higgs portal interaction. The relic abundance of can account for cold dark matter if the messenger mass satisfies GeV. Our model can be implemented in many realistic supersymmetric models such as the next-to-minimal supersymmetric (SUSY) standard model and nearly minimal SUSY standard model