Market Power and Patent Strategies: Evidence from Renaissance Venice

This paper exploits the introduction of the first regularized patent system, which appeared in the Venetian Republic in 1474, to examine the factors shaping inventors\u2019 propensity to use a new form of intellectual property. We combine detailed information on craft guilds and patents in Renaissance Venice and show a negative association between patenting activity and guild statutory norms that strongly restricted entry and price competition. Our analysis shows that the heterogeneity in patenting activity documented by the industrial organization literature is not a special feature of modern technologies, but is rather a persistent phenomenon affected by market power

Isolation and mapping of a C3'H gene (CYP98A49) from globe artichoke, and its expression upon UV-C stress

Globe artichoke represents a natural source of phenolic compounds with dicaffeoylquinic acids along with their biosynthetic precursor chlorogenic acid (5-caffeoylquinic acid) as the predominant molecules. We report the isolation and characterization of a full-length cDNA and promoter of a globe artichoke p-coumaroyl ester 3¿-hydroxylase (CYP98A49), which is involved in both chlorogenic acid and lignin biosynthesis. Phylogenetic analyses demonstrated that this gene belongs to the CYP98 family. CYP98A49 was also heterologously expressed in yeast, in order to perform an enzymatic assay with p-coumaroylshikimate and p-coumaroylquinate as substrates. Real Time quantitative PCR analysis revealed that CYP98A49 expression is induced upon exposure to UV-C radiation. A single nucleotide polymorphism in the CYP98A49 gene sequence of two globe artichoke varieties used for genetic mapping allowed the localization of this gene to linkage group 10 within the previously developed map

Source mechanisms and rupture processes of the Jujuy seismic nest, Chile-Argentina border

The Altiplano-Puna plateau, in Central Andes, is the second-largest continental plateau on Earth, extending between 22◦ and 27◦S at an average altitude of 4400 m. The Puna plateau has been formed in consequence of the subduction of the oceanic Nazca Plate beneath the continental South American plate, which has an average crustal thickness of 50 km at this location. A large seismicity cluster, the Jujuy cluster, is observed at depth of 150–250 km beneath the central region of the Puna plateau. The cluster is seismically very active, with hundreds of earthquakes reported and a peak magnitude MW 6.6 on 25th August 2006. The cluster is situated in one of three band of intermediate-depth focus seismicity, which extend parallel to the trench roughly North to South. It has been hypothesized that the Jujuy cluster could be a seismic nest, a compact seismogenic region characterized by a high stationary activity relative to its surroundings. In this study, we collected more than 40 years of data from different catalogs and proof that the cluster meets the three conditions of a seismic nest. Compared to other known intermediate depth nests at Hindu Kush (Afganisthan) or Bucaramanga (Colombia), the Jujuy nest presents an outstanding seismicity rate, with more than 100 M4+ earthquakes per year. We additionally performed a detailed analysis of the rupture process of some of the largest earthquakes in the nest, by means of moment tensor inversion and directivity analysis. We focused on the time period 2017–2018, where the seismic monitoring was the most extended. Our results show that earthquakes in the nest take place within the eastward subducting oceanic plate, but rupture along sub-horizontal planes dipping westward. We suggest that seismicity at Jujuy nest is controlled by dehydration processes, which are also responsible for the generation of fluids ascending to the crust beneath the Puna volcanic region. We use the rupture plane and nest geometry to provide a constraint to maximal expected magnitude, which we estimate as MW ~6.7.National Commission for Scientific and Technological Research (ANID-Becas Chile, Chile)European Unions Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant 754446UGR Research and Knowledge Transfer FoundAthenea3iGerman Research Foundation (DFG) 40714155

The reintroduction of Castor fiber in Piedmont (Italy): An integrated SWOT-spatial multicriteria based approach for the analysis of suitability scenarios

The Castor fiber or Eurasian beaver can change its habitat by building dams and creating ponds. For this reason, Castor fiber is known as an “ecosystem engineer” for aquatic and riparian environments. Despite its ecological importance, at the beginning of the 20th century the population was reduced to only 1200 beavers in Europe and Asia, due to uncontrolled hunting. Recently, some reintroductions and translocations have partly re-established the population. In Italy, however, the beaver disappeared in the 16th century and no action has been taken despite the recommendation of the Council of Europe to perform a feasibility study. This research evaluates beaver reintroduction and identifies suitable areas in Italy and, in particular, in the Piedmont region. In order to achieve this, a SWOT analysis combined with a Spatial Multicriteria Analysis was performed. Firstly, the zoological and ethological aspects concerning this rodent were studied, as well as the historical reasons that led to its disappearance in Italy and near extinction in Eurasia. Secondly, Strengths, Weaknesses, Opportunities and Threats (SWOT) of the territory were identified for beaver reintroduction. The SWOT analysis was implemented, as the starting point for the spatial multicriteria analysis. Thirdly, the Multicriteria Spatial Decision Support System (MC-SDSS) was structured into two criteria, i.e. Potentials and Criticalities, representing the spatialization of strengths and weaknesses. The final result of the MC-SDSS is a map showing suitable areas for beaver reintroduction in Piedmont. This map is the weighted sum of the maps of criticalities and potentialities, performed through a set of GIS operations and weighted through a pairwise comparison of criteria by experts. The analysis was conducted for the Piedmont region, but the integrated approach and the set of criteria can also be applied in other regions. Moreover, this mixed-method approach takes into account the characteristics necessary for the choice of suitable beaver habitats and also includes economic and social aspects. Therefore, it is an improvement on the Habitat Suitability Index (HIS), generally used in reintroductions. The aspects considered in the analysis are fundamental for the future development of a shared action plan, which considers both technical and social motivations and acts for the long-term on a wide area

The age of vines as a controlling factor of soil erosion processes in Mediterranean vineyards

Vineyards incur the highest soil and water losses among all Mediterranean agricultural fields. The state-of-the-art shows that soil erosion in vineyards has been primarily surveyed with topographical methods, soil erosion plots and rainfall simulations, but these techniques do not typically assess temporal changes in soil erosion. When vines are planted they are about 30 cm high × 1 cm diameter without leaves, the root system varies from 2 to over 40 cmdepth, and sometimes the lack of care used during transplanting can result in a field with highly erodible bare soils. This means that the time since vine plantation plays a key role in soil erosion rates, but very little attention has been paid to this by the scientific community. Thus, the main goal of this research was to estimate soil losses and assess soil erosion processes in two paired vineyard plantations of different ages. To achieve this goal, the improved stock unearthing method (ISUM) was applied to vineyards on colluvial parent materials with similar soil properties, topographical characteristics and landmanagements in the Les Alcusses Valley, southwestern Valencia province, Spain. Our findings suggested that the old vineyards showed lower erosion rates (−1.61 Mg ha−1 yr−1) than those that were recently planted (−8.16 Mg ha−1 yr−1). This is because of the damage that the plantation of the vines causes to soil. Tillage after planting (4 times per year) resulted in changes in the inter-rowand rowmorphology, promoting the development of a ridge underneath the vines that disconnected the inter-rows and reduced soil losseswith time. After the second year and until the 25th year after plantation, soil erosionwas approximately 1Mg ha−1 y−1,whichmeans thatmost of the erosion took place during the first two years after the plantation. Soil conservation strategies should be applied immediately after the plantationworks to allow sustainable grape production. That is when soil erosion most needs to be controlled

Role of rock fragment cover on runoff generation and sediment yield in tilled vineyards.

The soil in conventional Mediterranean vineyards is an active and non-sustainable source of sediment and water. Lack of vegetation cover, small soil organic matter content and intense ploughing result in large rates of erosion in a millennia-old tillage system. There is a need for soil conservation strategies that enable sustainability of wine and grape production; therefore, it is essential to measure the rates and to investigate the processes and factors of soil erosion. This study evaluated factors that can reduce soil losses in traditional Mediterranean vineyards. The investigation was carried out with 96 rainfall simulation experiments at the pedon scale (0.24m2) to measure soil detachment and runoff yield under low frequency-high magnitude rainfall events of 1 hour at 55mmhour−1. On average, runoff was 40.6% of the rainfall, and the rate of soil erosion (i.e. amount of soil lost) was 71.5 g m−2. The key factor controlling erosion was the rock fragment cover. There was a clear decrease in soil losses with increased rock fragment cover on the soil surface, but an increase in surface runoff. The results of our study showed that rock fragments at the pedon scale reduced soil erosion in Mediterranean vineyards, but when a layer of embedded rock fragments developed, large rates of runoff were triggered

Evaluation of multi-hazard map produced using MaxEnt machine learning technique

Natural hazards are diverse and uneven in time and space, therefore, understanding its complexity is key to save human lives and conserve natural ecosystems. Reducing the outputs obtained after each modelling analysis is key to present the results for stakeholders, land managers and policymakers. So, the main goal of this survey was to present a method to synthesize three natural hazards in one multi-hazard map and its evaluation for hazard management and land use planning. To test this methodology, we took as study area the Gorganrood Watershed, located in the Golestan Province (Iran). First, an inventory map of three different types of hazards including flood, landslides, and gullies was prepared using field surveys and different official reports. To generate the susceptibility maps, a total of 17 geo-environmental factors were selected as predictors using the MaxEnt (Maximum Entropy) machine learning technique. The accuracy of the predictive models was evaluated by drawing receiver operating characteristic-ROC curves and calculating the area under the ROC curve-AUCROC. The MaxEnt model not only implemented superbly in the degree of fitting, but also obtained significant results in predictive performance. Variables importance of the three studied types of hazards showed that river density, distance from streams, and elevation were the most important factors for flood, respectively. Lithological units, elevation, and annual mean rainfall were relevant for detecting landslides. On the other hand, annual mean rainfall, elevation, and lithological units were used for gully erosion mapping in this study area. Finally, by combining the flood, landslides, and gully erosion susceptibility maps, an integrated multi-hazard map was created. The results demonstrated that 60% of the area is subjected to hazards, reaching a proportion of landslides up to 21.2% in the whole territory. We conclude that using this type of multi-hazard map may be a useful tool for local administrators to identify areas susceptible to hazards at large scales as we demonstrated in this research

Analysis of milk using a portable potentiometric electronic tongue based on five polymeric membrane sensors

A portable potentiometric electronic tongue (PE-tongue) was developed and applied to evaluate the quality of milk with different fat content (skimmed, semi-skimmed, and whole) and with different nutritional content (classic, calcium-enriched, lactose-free, folic acid-enriched, and enriched in sterols of vegetal origin). The system consisted of a simplified array of five sensors based on PVC membranes, coupled to a data logger. The five sensors were selected from a larger set of 20 sensors by applying the genetic algorithm (GA) to the responses to compounds usually found in milk including salts (KCl, CaCl2, and NaCl), sugars (lactose, glucose, and galactose), and organic acids (citric acid and lactic acid). Principal component analysis (PCA) and support vector machine (SVM) results indicated that the PE-tongue consisting of a five-electrode array could successfully discriminate and classify milk samples according to their nutritional content. The PE-tongue provided similar discrimination capability to that of a more complex system formed by a 20-sensor array. SVM regression models were used to predict the physicochemical parameters classically used in milk quality control (acidity, density, %proteins, %lactose, and %fat). The prediction results were excellent and similar to those obtained with a much more complex array consisting of 20 sensors. Moreover, the SVM method confirmed that spoilage of unsealed milk could be correctly identified with the simplified system and the increase in acidity could be accurately predicted. The results obtained demonstrate the possibility of using the simplified PE-tongue to predict milk quality and provide information on the chemical composition of milk using a simple and portable system.We appreciate the financial support of MINECO-FEDER Plan Nacional (RTI 2018-097990-B-100) and Junta de Castilla y Leon - FEDER (VA275P18) and “Infraestructuras Red de Castilla y León (INFRARED)” UVA01info:eu-repo/semantics/publishedVersio