Utilización de los servicios de salud mental de Alcalá de Henares. Características.

El presente trabajo, describe un estudio de 589 casos, correspondientes a la demanda solicitada por primera vez, en los Servicios de Salud Mental de Alcalá de Henares de la CAM entre abril de 1987 (fecha de apertura) y septiembre de 1988: encontrando que esta demanda no corresponde a una población marginal. sino normalizada. y que asimismo son las mujeres aquejadas de T. Neuróticos. las que más acuden a estos Servicios en busca de ayuda. Analizamos descriptivamente algunas de las características de esta población. hallando unos determinados perfiles según diagnóstico

Utilización de los servicios de salud mental de Alcalá de Henares. Características.

El presente trabajo, describe un estudio de 589 casos, correspondientes a la demanda solicitada por primera vez, en los Servicios de Salud Mental de Alcalá de Henares de la CAM entre abril de 1987 (fecha de apertura) y septiembre de 1988: encontrando que esta demanda no corresponde a una población marginal. sino normalizada. y que asimismo son las mujeres aquejadas de T. Neuróticos. las que más acuden a estos Servicios en busca de ayuda. Analizamos descriptivamente algunas de las características de esta población. hallando unos determinados perfiles según diagnóstico

Utilización de los servicios de salud mental de Alcalá de Henares. Características.

El presente trabajo, describe un estudio de 589 casos, correspondientes a la demanda solicitada por primera vez, en los Servicios de Salud Mental de Alcalá de Henares de la CAM entre abril de 1987 (fecha de apertura) y septiembre de 1988: encontrando que esta demanda no corresponde a una población marginal. sino normalizada. y que asimismo son las mujeres aquejadas de T. Neuróticos. las que más acuden a estos Servicios en busca de ayuda. Analizamos descriptivamente algunas de las características de esta población. hallando unos determinados perfiles según diagnóstico

Early vascular endothelial complications after hematopoietic cell transplantation: Role of the endotheliopathy in biomarkers and target therapies development

This work aims to review the role of endothelial dysfunction underlying the main complications appearing early after autologous and allogeneic hematopoietic cell transplantation (HCT). The endothelial damage as the pathophysiological substrate of sinusoidal obstruction syndrome (SOS) is well established. However, there is growing evidence of the involvement of endothelial dysfunction in other complications, such as acute graft-versus-host disease (aGVHD) and transplant-associated thrombotic microangiopathy (TA-TMAs). Moreover, HCT-related endotheliopathy is not only limited to the HCT setting, as there is increasing evidence of its implication in complications derived from other cellular therapies. We also review the incidence and the risk factors of the main HCT complications and the biological evidence of the endothelial involvement and other linked pathways in their development. In addition, we cover the state of the art regarding the potential use of the biomarkers of endotheliopathy in the prediction, the early diagnosis, and the follow-up of the HCT complications and summarize current knowledge points to the endothelium and the other linked pathways described as potential targets for the prevention and treatment of HCT-complications. Lastly, the endothelium-focused therapeutic strategies that are emerging and might have a potential impact on the survival and quality of life of post-HCT-patients are additionally reviewed.Copyright © 2022 Moreno-Castaño, Salas, Palomo, Martinez-Sanchez, Rovira, Fernández-Avilés, Martínez, Cid, Castro, Escolar, Carreras and Diaz-Ricart

Adsorption of Phenol from Aqueous Solutions by Carbon Nanomaterials of One and Two Dimensions: Kinetic and Equilibrium Studies

Carbon nanomaterials have a great potential in environmental studies; they are considered as superior adsorbents of pollutants due to their physical and chemical properties. Functionalization and dimension play an important role in many functions of these nanomaterials including adsorption. In this research, adsorption process was achieved with one-dimension nanomaterials: single walled and multiwalled carbon nanotubes were used as received and after oxidation treatment also two-dimensional nanomaterials were used: graphene oxide and reduced graphene oxide. Carbon nanotubes were modified by hydrogen peroxide under microwave irradiation. The reduction of graphene oxide was achieved by using ascorbic acid. R2 values obtained with the pseudo-second-order model are higher than 0.99. The results demonstrate that Freundlich isotherm provides the best fit for the equilibrium data (R2>0.94). RL values are between 0 and 1; this represents favorable adsorption between carbon nanomaterials and phenol. The adsorption process occurs by π-π interactions and hydrogen bonding and not by electrostatic interactions. The results indicate that the adsorption of phenol on carbon nanomaterials depends on the adsorbents’ surface area, and it is negatively influenced by the presence of oxygenated groups

Peripheral and placental immune responses in sheep after experimental infection with "Toxoplasma gondii" at the three terms of gestation

P. 1-9Although it is known that gestation could infuence the clinical course of ovine toxoplasmosis, the precise efect of the term of gestation when sheep are infected are yet mostly unknown. The aim of this study was to evaluate the peripheral and placental immune responses developed in pregnant sheep after experimental infection with Toxoplasma gondiiat diferent times of gestation. Thirty‑six pregnant sheep were allocated in diferent groups, orally inocu‑lated with sporulated oocysts of T. gondiiat early, mid and late gestation and culled within 30 days post‑infection. The peripheral humoral and cytokine responses were evaluated, as well as the transcription of cytokines at the placenta. Serological analysis revealed that, regardless the term of gestation when infected, specifc IgG against T. gondiiwere detected from day 8 post‑infection and there was an early peripheral release of IFN‑γ at the frst week post‑infection followed by a short peak of IL10 and TNF‑α at the second week post‑infection. There were no signifcant diferences in this response between infected groups. At the placenta, a similar increase in transcription of IFN‑γ, and TNF‑α was found at the three terms of gestation, while IL‑4 increased mainly at the frst and second terms and IL‑10 transcription was higher at the last term. While these fndings show that both Th1 and Th2 cytokines play a key role in the patho‑genesis of ovine toxoplasmosis and that placental and peripheral immune responses do not closely correlate, there seems to be no clear modulation of these responses along the gestation.S