Tonsillar ulceration as manifestation of disseminated African histoplasmosis in an immunocompetent Portuguese host

Free PMC Article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466580/Histoplasmosis is a systemic mycosis caused by Histoplasma capsulatum. Rare in Europe but endemic in some regions of Brazil, United States, Africa and Asia. Most of the cases are asymptomatic. Disseminated form is defined by the presence of an extra-pulmonary focus, particularly associated with immunosuppression. We report a case of an unilateral persisted tonsillar ulceration, in an immunocompetent Portuguese host, as manifestation of disseminated African histoplasmosis 45 years later after living 3 years in Africa.info:eu-repo/semantics/publishedVersio

Tonsillar ulceration as manifestation of disseminated African histoplasmosis in an immunocompetent Portuguese host

Free PMC Article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466580/Histoplasmosis is a systemic mycosis caused by Histoplasma capsulatum. Rare in Europe but endemic in some regions of Brazil, United States, Africa and Asia. Most of the cases are asymptomatic. Disseminated form is defined by the presence of an extra-pulmonary focus, particularly associated with immunosuppression. We report a case of an unilateral persisted tonsillar ulceration, in an immunocompetent Portuguese host, as manifestation of disseminated African histoplasmosis 45 years later after living 3 years in Africa.info:eu-repo/semantics/publishedVersio

Resposta de Pinus taeda L. na aplicação de cinza de biomassa vegetal em cambissolo húmico, em vaso.

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Resposta de Pinus taeda L. à aplicação de cinza de biomassa vegetal em Cambissolo Húmico, em vaso.

Foi avaliado o efeito de doses de cinza de biomassa vegetal, equivalentes a 0; 10; 20; 40 e 80 t.ha-1, sobre características químicas do solo e sobre o desenvolvimento e absorção de nutrientes por mudas de Pinus taeda L., em casa-de-vegetação da Embrapa Florestas, em Colombo, PR, em Cambissolo Húmico, coletado na camada de 0 a 20 cm, em Piraí do Sul, PR. Porções da amostra do solo foram colocadas em vasos, sendo as alíquotas de cada tratamento aplicadas na camada de 0 a 10 cm, após preencher os vasos com 20 cm de solo. Foram analisadas as acículas e o solo (camadas 0 a 10 cm, 10 cm a 20 cm e 20 cm a 30 cm). Avaliaram-se a altura, o diâmetro e as massas secas da parte aérea, da raiz - MSR e total. A aplicação da cinza diminuiu a acidez e o teor de Al, e aumentou os teores de Ca, Mg, K e P, com efeitos mais pronunciados na camada de 0 a 10 cm; não houve efeito dos tratamentos no desenvolvimento das mudas; o teor de Cu nas acículas foi diminuído com o aumento da dose de cinza

Lysophosphatidylcholine: A Novel Modulator of Trypanosoma cruzi Transmission

Lysophosphatidylcholine is a bioactive lipid that regulates a large number of cellular processes and is especially present during the deposition and infiltration of inflammatory cells and deposition of atheromatous plaque. Such molecule is also present in saliva and feces of the hematophagous organism Rhodnius prolixus, a triatominae bug vector of Chagas disease. We have recently demonstrated that LPC is a modulator of Trypanosoma cruzi transmission. It acts as a powerful chemoattractant for inflammatory cells at the site of the insect bite, which will provide a concentrated population of cells available for parasite infection. Also, LPC increases macrophage intracellular calcium concentrations that ultimately enhance parasite invasion. Finally, LPC inhibits NO production by macrophages stimulated by live T. cruzi, and thus interferes with the immune system of the vertebrate host. In the present paper, we discuss the main signaling mechanisms that are likely used by such molecule and their eventual use as targets to block parasite transmission and the pathogenesis of Chagas disease

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Efficient edge domination in regular graphs

An induced matching of a graph G is a matching having no two edges joined by an edge. An efficient edge dominating set of G is an induced matching M such that every other edge of G is adjacent to some edge in M. We relate maximum induced matchings and efficient edge dominating sets, showing that efficient edge dominating sets are maximum induced matchings, and that maximum induced matchings on regular graphs with efficient edge dominating sets are efficient edge dominating sets. A necessary condition for the existence of efficient edge dominating sets in terms of spectra of graphs is established. We also prove that, for arbitrary fixed p 3, deciding on the existence of efficient edge dominating sets on p-regular graphs is NP-complet