283 research outputs found

    Review: The effect of nutrition on timing of pubertal onset and subsequent fertility in the bull

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    peer-reviewedThe advent of genomic selection has led to increased interest within the cattle breeding industry to market semen from young bulls as early as possible. However, both the quantity and quality of such semen is dictated by the age at which these animals reach puberty. Enhancing early life plane of nutrition of the bull stimulates a complex biochemical interplay involving metabolic and neuroendocrine signalling and culminating in enhanced testicular growth and development and earlier onset of sexual maturation. Recent evidence suggests that an enhanced plane of nutrition leads to an advancement of testicular development in bulls at 18 weeks of age. However, as of yet, much of the neuronal mechanisms regulating these developmental processes remain to be elucidated in the bull. While early life nutrition clearly affects the sexual maturation process in bulls, there is little evidence for latent effects on semen traits post-puberty. Equally the influence of prevailing nutritional status on the fertility of mature bulls is unclear though management practices that result in clinical or even subclinical metabolic disease can undoubtedly impact upon normal sexual function. Dietary supplements enriched with various polyunsaturated fatty acids or fortified with trace elements do not consistently affect reproductive function in the bull, certainly where animals are already adequately nourished. Further insight on how nutrition mediates the biochemical interaction between neuroendocrine and testicular processes will facilitate optimisation of nutritional regimens to optimise sexual maturation and subsequent semen production in bulls

    The effect of geographic location on circannual adrenocorticotropic hormone plasma concentrations in horses in Australia

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    Background: Longitudinal evaluation of plasma endogenous ACTH concentration in clinically normal horses has not been investigated in the Southern Hemisphere. Objectives: To longitudinally determine monthly upper reference limits for plasma ACTH in 2 disparate Australian geographic locations and to examine whether location affected the circannual rhythm of endogenous ACTH in the 2 groups of horses over a 12-month period. Animals: Clinically normal horses <20 years of age from 4 properties (institutional herd and client owned animals) in Perth (n = 40) and Townsville (n = 41) were included in the study. Methods: A prospective longitudinal descriptive study to determine the upper reference limit and confidence intervals for plasma ACTH in each geographic location using the ASVCP reference interval (RI) guidelines, for individual months and monthly groupings for 12 consecutive months. Results: Plasma endogenous ACTH concentrations demonstrated a circannual rhythm. The increase in endogenous ACTH was not confined to the autumnal months but was associated with changes in photoperiod. During the quiescent period, plasma ACTH concentrations were lower, ≤43 pg/mL (upper limit of the 90% confidence interval (CI)) in horses from Perth and ≤67 pg/mL (upper limit of the 90% CI) in horses from Townsville, than at the acrophase, ≤94 pg/mL (upper limit of the 90% CI) in horses from Perth, ≤101 pg/mL (upper limit of the 90% CI) in horses from Townsville. Conclusions and Clinical Importance: Circannual rhythms of endogenous ACTH concentrations vary between geographic locations, this could be due to changes in photoperiod or other unknown factors, and upper reference limits should be determined for specific locations

    Speeds and arrival times of solar transients approximated by self-similar expanding circular fronts

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    The NASA STEREO mission opened up the possibility to forecast the arrival times, speeds and directions of solar transients from outside the Sun-Earth line. In particular, we are interested in predicting potentially geo-effective Interplanetary Coronal Mass Ejections (ICMEs) from observations of density structures at large observation angles from the Sun (with the STEREO Heliospheric Imager instrument). We contribute to this endeavor by deriving analytical formulas concerning a geometric correction for the ICME speed and arrival time for the technique introduced by Davies et al. (2012, ApJ, in press) called Self-Similar Expansion Fitting (SSEF). This model assumes that a circle propagates outward, along a plane specified by a position angle (e.g. the ecliptic), with constant angular half width (lambda). This is an extension to earlier, more simple models: Fixed-Phi-Fitting (lambda = 0 degree) and Harmonic Mean Fitting (lambda = 90 degree). This approach has the advantage that it is possible to assess clearly, in contrast to previous models, if a particular location in the heliosphere, such as a planet or spacecraft, might be expected to be hit by the ICME front. Our correction formulas are especially significant for glancing hits, where small differences in the direction greatly influence the expected speeds (up to 100-200 km/s) and arrival times (up to two days later than the apex). For very wide ICMEs (2 lambda > 120 degree), the geometric correction becomes very similar to the one derived by M\"ostl et al. (2011, ApJ, 741, id. 34) for the Harmonic Mean model. These analytic expressions can also be used for empirical or analytical models to predict the 1 AU arrival time of an ICME by correcting for effects of hits by the flank rather than the apex, if the width and direction of the ICME in a plane are known and a circular geometry of the ICME front is assumed.Comment: 15 pages, 5 figures, accepted for publication in "Solar Physics

    Magmatic Origins of Extensional Structures in Tempe Terra, Mars

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    Abstract Numerous graben features transect the Tempe Terra plateau in the northeastern Tharsis Rise, Mars, making it one of the most heavily structured regions of Tharsis. The origin of the complex fault geometries, generated over three distinct stages of tectonic activity, is poorly understood. This work distinguishes between Tempe Terra structures of local and regional origin, to isolate regional deformation patterns related to the general development of the Tharsis Rise from the patterns due to effects of local stress mechanisms. Comparison of structural observations to predicted deformation patterns from different drivers of graben formation in the Martian crust demonstrates the important role of magmatic activity at a variety of scales in driving tectonism in Tempe Terra. Noachian (Stage 1) faulting resulted from local magmatic underplating and associated heating and uplift, which formed part of an incipient stage of widespread Tharsis volcanism that predated development of the main Tharsis Rise. Early Hesperian (Stage 2) faults reflect the interaction of regional stresses from growth of Tharsis with magmatic activity highly localized along the Tharsis Montes Axial Trend—a linear volcanotectonic trendline including the alignment of the Tharsis Montes volcanoes. Early–Late Hesperian (Stage 3) faulting resulted from a series of dyke swarms from a Tharsis-centered plume, which propagated in a regional stress field generated by growth of the Tharsis Rise. As only Stage 2 NNE faults and Stage 3 ENE faults are linked to regional, Tharsis-related stresses, other observed Tempe Terra fault trends can be excluded when evaluating models of Tharsis's tectonic evolution. Key Points The 3 stages of Tempe Terra's tectonic activity have different origins, with local and regional scale magmatic sources driving deformation Magmatectonic activity began in Tempe Terra prior to development of the Tharsis Rise topographic bulge and associated major volcanoes Only 2 Tempe Terra fault trends (NNE and ENE), both Hesperian age, represent stresses related to the growth of the Tharsis Rise Plain Language Summary Tharsis is the largest volcanic province on Mars and its formation was a major driver of the deformation we see at the surface. Tectonic structures that record this deformation are therefore used to understand how and when Tharsis formed. However, local structural patterns may obscure regional trends associated with Tharsis-forming stresses, complicating our ability to assess models for how Tharsis developed. As such, distinguishing between faults with local and regional origins is essential. We study the Tempe Terra region in northeastern Tharsis to determine the origin of the region's extensive faulting, generated over three stages of tectonic activity. By comparing surface observations to expected evidence of different sources of stress, such as uplift from local volcanoes or dyke intrusion, we found that each stage of tectonic activity had a different origin. A combination of local (from within Tempe Terra) and regional (from Tharsis) magmatic sources drove deformation, and tectonic activity began before the main structures and volcanoes of Tharsis had developed. Only two fault trends in Tempe Terra can be linked to regional stresses related to the growth of Tharsis: NNE-trending and ENE-trending faults. Isolating these regional trends provides clearer criteria for assessing models of Tharsis development in the future

    A pre-post study of behavioural determinants and practice change in Ugandan clinical officers

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    Background. Understanding the drivers of ‘provider behaviour’ has been highlighted as one of the six domains of behaviour change in strengthening healthcare systems.Objectives. To assess changes in healthcare provider behaviour, i.e. use of the Airway, Breathing, Circulation, Disability, Exposure (ABCDE) approach in acute illness management, after participating in a 1-day course on the assessment and management of acutely ill patients. We aimed to assess whether changes in psychological determinants of the ABCDE approach were associated with changes in the use of the approach.Methods. We used a pre-post design to study self-reported change in behaviour after a 1-day training course from pre-course to follow-up 1 month later. We also measured psychological determinants of behaviour immediately before and after and at 1-month follow-up. We explored if changes in psychological determinants were associated with change in practice 1 month later.Results. We found the following: firstly, use of the ABCDE approach increased at 1 month post-course from a median use of 50 - 90%. Secondly, the increase in the ABCDE approach was associated with a positive change in only one of the determinants of practice from pre- to post-course: perception of environmental determinants (r=0.323; p&lt;0.05). Finally, there were no other significant associations with practice change or practice at follow-up.Conclusions. Change in perceptions of availability of resources was associated with increased use of an ABCDE approach, but evidence was limited owing to the pre-post design

    Automated Detection of Coronal Loops using a Wavelet Transform Modulus Maxima Method

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    We propose and test a wavelet transform modulus maxima method for the au- tomated detection and extraction of coronal loops in extreme ultraviolet images of the solar corona. This method decomposes an image into a number of size scales and tracks enhanced power along each ridge corresponding to a coronal loop at each scale. We compare the results across scales and suggest the optimum set of parameters to maximise completeness while minimising detection of noise. For a test coronal image, we compare the global statistics (e.g., number of loops at each length) to previous automated coronal-loop detection algorithms

    Effect of Solar Wind Drag on the Determination of the Properties of Coronal Mass Ejections from Heliospheric Images

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    The Fixed-\Phi (F\Phi) and Harmonic Mean (HM) fitting methods are two methods to determine the average direction and velocity of coronal mass ejections (CMEs) from time-elongation tracks produced by Heliospheric Imagers (HIs), such as the HIs onboard the STEREO spacecraft. Both methods assume a constant velocity in their descriptions of the time-elongation profiles of CMEs, which are used to fit the observed time-elongation data. Here, we analyze the effect of aerodynamic drag on CMEs propagating through interplanetary space, and how this drag affects the result of the F\Phi and HM fitting methods. A simple drag model is used to analytically construct time-elongation profiles which are then fitted with the two methods. It is found that higher angles and velocities give rise to greater error in both methods, reaching errors in the direction of propagation of up to 15 deg and 30 deg for the F\Phi and HM fitting methods, respectively. This is due to the physical accelerations of the CMEs being interpreted as geometrical accelerations by the fitting methods. Because of the geometrical definition of the HM fitting method, it is affected by the acceleration more greatly than the F\Phi fitting method. Overall, we find that both techniques overestimate the initial (and final) velocity and direction for fast CMEs propagating beyond 90 deg from the Sun-spacecraft line, meaning that arrival times at 1 AU would be predicted early (by up to 12 hours). We also find that the direction and arrival time of a wide and decelerating CME can be better reproduced by the F\Phi due to the cancellation of two errors: neglecting the CME width and neglecting the CME deceleration. Overall, the inaccuracies of the two fitting methods are expected to play an important role in the prediction of CME hit and arrival times as we head towards solar maximum and the STEREO spacecraft further move behind the Sun.Comment: Solar Physics, Online First, 17 page

    Plane of nutrition before and after 6 months of age in Holstein-Friesian bulls: I. Effects on performance, body composition, age at puberty, and postpubertal semen production

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    peer-reviewedABSTRACTThe aim of this study was to examine the effect of plane of nutrition (1) during the first 6 mo of life and (2) from 6 mo of age to puberty on early growth characteristics, age at puberty, and postpubertal semen production in Holstein-Friesian bulls. Holstein-Friesian bull calves (n = 83) with a mean (standard deviation) age and body weight of 17 (4.4) d and 52 (6.2) kg, respectively, were assigned to a high (Hi) or low (Lo) plane of nutrition for the first 6 mo of life. The Hi and Lo calves received 1,200 and 450 g of milk replacer, respectively; Hi calves were fed concentrate ad libitum and Lo were fed a maximum of 1 kg concentrate daily, and concentrate allowances remained the same after weaning. At 24 wk of age, bulls were reassigned within treatment to either remain on the same diet or to switch to the opposite diet until puberty, resulting in 4 treatment groups: Hi-Hi, Hi-Lo, Lo-Lo, and Lo-Hi. After puberty, all bulls were fed a moderate plane of nutrition until 60 wk of age; thereafter, the diet was ad libitum concentrates until slaughter at 72 wk of age. Bulls were weighed weekly before weaning and every 2 wk after weaning. Scrotal circumference (SC) was measured every 2 wk, beginning at 15 wk of age. Beginning at a SC of 24 cm, electro-ejaculation was carried out every 2 wk to establish the onset of puberty. Semen collection continued monthly after puberty. Thermal images of the scrotum were taken monthly from 28 to 36 wk of age. Scrotal skin thickness (SST) was measured monthly (from 16 wk of age to puberty) using a digital calipers. Bulls on the Hi diet had a higher scrotal temperature and SST at each time point than those on the Lo diet. Average daily gain (ADG) was greatest in Hi-Hi bulls, with Hi-Lo and Lo-Hi having similar ADG but both being greater than Lo-Lo. Bulls on the Hi diet pre-6 mo of age were younger at puberty, regardless of diet offered post-6 mo of age. Bulls offered a Hi diet post-6 mo were heavier at puberty. Neither scrotal temperature nor dietary treatment affected postpubertal semen production variables. In conclusion, a high plane of nutrition during the first 6 mo of age hastened the onset of puberty and the availability of saleable semen, regardless of plane of nutrition post-6 mo of age

    Connections between high-K and low-K states in the s-process nucleus Lu176

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    Gamma-ray branches that connect high-K states to low-K states in the s-process nucleus Lu176 were observed, thus providing a link between the 58 Gyr, 7- ground state and the 5.3 h, 1- isomeric state. High sensitivity and unambiguous placement were achieved through the study of the decay of the 58 μs Kπ=14+ isomer using γ-γ-coincidence measurements. The large number of decay paths from the isomer provides a means of populating a broad selection of states from above, resulting, paradoxically, in higher sensitivity than in cases where low-spin input reactions are used. The out-of band decay widths important for excitation processes in stars are quantified
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