Pyomyositis in Nodding Syndrome (NS) patient - A case report

We report a case of Pyomyositis in a 13-year-old boy diagnosed using WHO surveillance definition of Probable Nodding syndrome. Complete blood count showed Leukocytosis with immature granulocytes and atypical lymphocytes. Except for the liver enzymes which were high the renal functions and serum electrolytes were within normal range values. Culture of a pus-swab grew Staphylococcus aureus. Abdominal ultrasound scan showed a focal mass on the internal and external oblique muscles of the right abdominal wall. Incision and drainage was performed. Histology of the muscle showed non-specific inflammation of the external and internal oblique muscles. This finding may highlight some of the other tropical diseases that occur in children with Nodding syndrome

Hematological and Serum Biochemical Analyses in Experimental Caprine Besnoitiosis

This study was undertaken to investigate the hematological and biochemical changes in experimentally infected goats with Besnoitia caprae from the time of infection till 360 days post-infection (PI). Six male goats were inoculated subcutaneously with 13×107 bradyzoites of B. caprae, and blood samples were collected from the jugular vein. The total erythrocyte and total leukocyte counts, hematocrit value, and differential leukocyte counts were determined. Serum biochemical analysis, including the total protein, albumin, total globulin, cholesterol, triglyceride, chloride, testosterone, calcium (Ca2+), inorganic phosphorus, sodium (Na+), potassium (K+), iron (Fe2+), glucose, serum amyloid A (SAA), haptoglobin (Hp), fibrinogen, ceruloplasmin, aspartate aminotransferase, alanine aminotransferase, creatine kinase, lactate dehydrogenase, and alkaline phosphatase, was undertaken. Skin biopsy from the limbs were collected at weekly intervals and histologically examined for Besnoitia cysts. Cysts were present in the skin biopsies of the leg of the infected goats from day 28 PI. There were variations in hematological analyses, but no significant difference was seen. From day 30 to 360 PI, results showed that SAA, Hp, fibrinogen, and ceruloplasmin concentrations increased, whereas testosterone concentrations decreased. Infected goats exhibited decrease of albumin and increase of serum total protein and globulin concentrations. By contrast, there were no significant differences in the remained analyses concentrations

Transplacental Transmission of Bluetongue Virus 8 in Cattle, UK

To determine whether transplacental transmission could explain overwintering of bluetongue virus in the United Kingdom, we studied calves born to dams naturally infected during pregnancy in 2007–08. Approximately 33% were infected transplacentally; some had compromised health. In all infected calves, viral load decreased after birth; no evidence of persistent infection was found

Buruli ulcers in Gulu Regional Referral Hospital, Northern Uganda: Case Report

Buruli ulcers (BU) is a disease caused by infection with Mycobacterium ulcerans. It is one of the most neglected but treatable tropical diseases. Cases of Buruli ulcers are extremely rare in Gulu District. It is because of this reason that we report a case of a 25 year old male patient who presented with Buruli ulcers on the right thigh

Rare Occurrence: Buruli Ulcers in Gulu, Northern Uganda. A case report.

A Buruli ulcer (BU) is a disease caused by infection with Mycobacterium ulcerans . It is one of the most neglected but treatable tropical diseases. The causative organism is from the family of mycobacteriacae which causes tuberculosis and leprosy. Buruli ulcer has received the least attention than these other two diseases. Its infection leads to extensive destruction of skin and soft tissue and formation of large ulcers usually on the legs or arms. Early diagnosis and treatment are vital in preventing such disabilities. We describe a case report of Buruli ulcer diagnosed using culture and histology and successfully managed in Gulu Regional Hospital using medical and surgical methods

Rare Occurrence: Buruli Ulcers in Gulu, Northern Uganda. A Case report

A Buruli ulcer (BU) is a disease caused by infection with Mycobacterium ulcerans. It is one of the most neglected but treatable tropical diseases. The causative organism is from the family of mycobacteriacae which causes tuberculosis and leprosy. Buruli ulcer has received the least attention than these other two diseases. Its infection leads to extensive destruction of skin and soft tissue and formation of large ulcers usually on the legs or arms. Early diagnosis and treatment are vital in preventing such disabilities. We describe a case report of Buruli ulcer diagnosed using culture and histology and successfully managed in Gulu Regional Hospital using medical and surgical methods.East and Central African Journal of Surgery. 2011 Nov/ December;16 (3

Norcardiosis in Dogs in Zimbabwe: Two Cases

Two cases of canine norcardiosis are reported. The first case was an 18-month-old Rottweiller which had a long history of dyspnoea and died of respiratory distress. At necropsy there was pyothorax containing sulphur granules, which had mixed colonies of Norcardia and Corynebacterium species. The second case was a 21/2 year-old Pointer bitch which lost weight and had hindlimb ataxia due to lesions in the vertebrae and spinal cord. Granulomatous nodules containing colonies of Norcardia species were found in the sublumbar muscles, lungs and pleura. These cases confirm the occurrence of norcardiosis in Zimbabwe. The Kenya Veterinarian Vol. 18 (1) 1994: pp. 6-

Pyomyositis and its risk factors in patients of Gulu Regional Referral Hospital, Uganda. A Descriptive Cross-sectional Study Design

Background: Pyomyositis is a suppurative infection of the skeletal muscles and is characterized by localized muscle pains, swelling and tenderness. Pyomyositis accounts for 10-15% of hospital admissions in some units in northern Uganda. We described the demographic characteristics and risk factors of Pyomyositis patients treated at Gulu Hospital between January to September 2009. Methods: A descriptive cross-sectional study was conducted on Pyomyositis patients admitted in Gulu Regional hospital surgical ward over a period of 9 months (January 2009 to September 2009). One hundred patients who met the inclusion criteria were consecutively recruited in to the study after obtaining an informed consent. The patients’ information was recorded on a special questionnaire. The information recorded included the demographic characteristic, the BMI, sites of infection and the laboratory tests findings. Each patient underwent incision and drainage (I&D) operation and was followed up in the outpatient department for postoperative surgical review. Ethical consideration and approval was obtained from the ethical review committee and administration of Gulu Regional Hospital. Results: The population study consisted of 100 patients. The patients’ ages ranged from 12 to 60 with a mean of 30.3 years. The peak age range was 30-34 years. The male to female (M: F) ratio of 1:1.1. Of the risk factors studied trauma was reported in 7 patients (7%). Malnutrition (53%) and HIV/AIDS (40%) were the commonest risk factors. None of the patients suffered from Diabetes mellitus or hypertension. HIV/AIDS was present in 88% of the malnourished pyomyositis patients. Conclusion: Malnutrition is the commonest risk factor to pyomyositis, followed by HIV/AIDS and trauma. Most malnourished patients were HIV positive.East and Central African Journal of Surgery. 2011 Nov/ December;16 (3