The Stories Behind the Story (Foreword and Introduction to Introducing Evangelical Ecotheology: Foundations in Scripture, Theology, History, and Praxis)

Excerpt: Nathan and I (Dan) pulled into the Mbanhela community in the Gaza province of Mozambique and were greeted by the high-spirited singing of six women who form the livestock association of that small community. A Christian relief and development organization, of which Nathan is the country director, provided funds for a large chicken coop, feed, supplies, and 300 chickens for the Mbanhela community. In addition, it furnished training in basic animal husbandry and marketing. Every two months the community starts a new cycle with 320 chicks. Raising chickens for income empowers that community and helps it toward health and sustainability. But the goal of raising livestock is not just for community development. The Mbanhela community decided that God had called them to provide a home for twenty-nine orphans and other vulnerable children. (One woman, Pastor Ramira, said to us matter-of-factly, “God tells us to care for the orphans and widows, and so we do.”) Profits from the sale of the chickens help those children attend school and buy books and school supplies

Four New Planets Orbiting Metal-enriched Stars

Peer reviewe

The diversity and breadth of cancer cell fatty acid metabolism

Tumor cellular metabolism exhibits distinguishing features that collectively enhance biomass synthesis while maintaining redox balance and cellular homeostasis. These attributes reflect the complex interactions between cell-intrinsic factors such as genomic-transcriptomic regulation and cell-extrinsic influences, including growth factor and nutrient availability. Alongside glucose and amino acid metabolism, fatty acid metabolism supports tumorigenesis and disease progression through a range of processes including membrane biosynthesis, energy storage and production, and generation of signaling intermediates. Here, we highlight the complexity of cellular fatty acid metabolism in cancer, the various inputs and outputs of the intracellular free fatty acid pool, and the numerous ways that these pathways influence disease behavior.Shilpa R. Nagarajan, Lisa M. Butler, and Andrew J. Ho

Radio broadcasting for health: a decision maker's guide

Information and Communication for DevelopmentAndrew Skuse, Nadia Butler, Fiona Powe, Nicola Woods, Mary Myers, Nicola Harford, Heather Budge-Reid and Gordan Ada

Evaluation of human and non-human primate antibody binding to pig cells lacking GGTA1/CMAH/β4GalNT2 genes

Background Simultaneous inactivation of pig GGTA1 and CMAH genes eliminates carbohydrate xenoantigens recognized by human antibodies. The β4GalNT2 glycosyltransferase may also synthesize xenoantigens. To further characterize glycan-based species incompatibilities, we examined human and non-human primate antibody binding to cells derived from genetically modified pigs lacking these carbohydrate-modifying genes. Methods The Cas9 endonuclease and gRNA were used to create pigs lacking GGTA1, GGTA1/CMAH, or GGTA1/CMAH/β4GalNT2 genes. Peripheral blood mononuclear cells were isolated from these animals and examined for binding to IgM and IgG from humans, rhesus macaques, and baboons. Results Cells from GGTA1/CMAH/β4GalNT2 deficient pigs exhibited reduced human IgM and IgG binding compared to cells lacking both GGTA1 and CMAH. Nonhuman primate antibody reactivity with cells from the various pigs exhibited a slightly different pattern of reactivity than that seen in humans. Simultaneous inactivation of the GGTA1 and CMAH genes increased nonhuman primate antibody binding compared to cells lacking either GGTA1 only or to those deficient in GGTA1/CMAH/β4GalNT2. Conclusions Inactivation of the β4GalNT2 gene reduces human and nonhuman primate antibody binding resulting in diminished porcine xenoantigenicity. The increased humoral immunity of nonhuman primates towards GGTA1/CMAH-deficient cells compared to pigs lacking either GGTA1 or GGTA1/CMAH/β4GalNT2 highlights the complexities of carbohydrate xenoantigens and suggests potential limitations of the nonhuman primate model for examining some genetic modifications. The progressive reduction of swine xenoantigens recognized by human immunoglobulin through inactivation of pig GGTA1/CMAH/β4GalNT2 genes demonstrates that the antibody barrier to xenotransplantation can be minimized by genetic engineering

Developmental contexts and features of elite academy football players: Coach and player perspectives

Player profiling can reap many benefits; through reflective coach-athlete dialogue that produces a profile the athlete has a raised awareness of their own development, while the coach has an opportunity to understand the athlete's viewpoint. In this study, we explored how coaches and players perceived the development features of an elite academy footballer and the contexts in which these features are revealed, in order to develop a player profile to be used for mentoring players. Using a Delphi polling technique, coaches and players experienced a number of 'rounds' of expressing their opinions regarding player development contexts and features, ultimately reduced into a consensus. Players and coaches had differing priorities on the key contexts of player development. These contexts, when they reflect the consensus between players and coaches were heavily dominated by ability within the game and training. Personal, social, school, and lifestyle contexts featured less prominently. Although 'discipline' was frequently mentioned as an important player development feature, coaches and players disagreed on the importance of 'training'

Stearyl methacrylate-based polymers as crystal habit modifiers for triacylglycerols

© 2018 American Chemical Society. Triacrylglycerols (TAGs) are ubiquitous and naturally occurring fat molecules that can make materials with diverse textural, mechanical, and optical properties. These properties are intimately linked to their complex hierarchical crystal structures, which can be controlled by additives that interfere with crystallization. A series of semicrystalline, bottlebrush-like copolymers have been developed to modify TAG crystallization and influence crystal habit. Synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization, these copolymer additives combine crystalline poly(stearyl methacrylate) with amorphous poly(oleyl methacrylate) in either block or statistical architecture. Upon cooling mixtures of these copolymers with solutions of tristearin (SSS) in triolein (OOO), the polymeric additives affected SSS crystallization at multiple length-scales. Microscopy analysis revealed control over SSS crystal morphology indicative of crystal aggregation, while small and wide-angle X-ray diffraction (SAXD/WAXD) offered insight into the underlying mechanism of action. Analyzing the physical broadening of lamellar peaks suggested that the fraction of amorphous poly(oleyl methacrylate) controls the thickness of primary nanoplatelets, and crystal structures derived from WAXD showed that the less stable α- or β′-polymorphs of SSS are stabilized by block or statistical copolymers, respectively. Exploiting these additives to simultaneously manipulate the packing of TAG molecules within lamellae, the size of primary crystallites, and the aggregation of crystallites could diversify fat material properties and supplement wide-ranging applications

Further evidence to justify reassignment of Mycoplasma mycoides subspecies mycoides Large Colony type to Mycoplasma mycoides subspecies capri

Analysis, using the polymerase chain reaction (PCR), restriction enzyme endonuclease analysis (REA), protein profile patterns, random amplification of polymorphic DNA (RAPD) fingerprinting, 16S rRNA gene sequencing and antisera growth inhibition tests, of 22 strains of Mycoplasma mycoides subsp. mycoides Large Colony type (MmmLC) and eight strains of M. mycoides subsp. capri (Mmc) are presented, along with a summary of comparative data from the literature for over 100 strains, all of which supports the reclassification of the MmmLC and Mmc strains into the single subspecies, M. mycoides subspecies capri

Mining and Visualizing Research Networks using the Artefact-Actor-Network Approach

Reinhardt, W., Wilke, A., Moi, M., Drachsler, H., & Sloep, P. B. (2012). Mining and Visualizing Research Networks using the Artefact-Actor-Network Approach. In A. Abraham (Ed.), Computational Social Networks. Mining and Visualization (pp. 233-268). Springer. Also available at http://www.springer.com/computer/communication+networks/book/978-1-4471-4053-5Virtual communities are increasingly relying on technologies and tools of the so-called Web 2.0. In the context of scientific events and topical Research Networks, researchers use Social Media as one main communication channel. This raises the question, how to monitor and analyze such Research Networks. In this chapter we argue that Artefact-Actor-Networks (AANs) serve well for modeling, storing and mining the social interactions around digital learning resources originating from various learning services. In order to deepen the model of AANs and its application to Research Networks, a relevant theoretical background as well as clues for a prototypical reference implementation are provided. This is followed by the analysis of six Research Networks and a detailed inspection of the results. Moreover, selected networks are visualized. Research Networks of the same type show similar descriptive measures while different types are not directly comparable to each other. Further, our analysis shows that narrowness of a Research Network's subject area can be predicted using the connectedness of semantic similarity networks. Finally conclusions are drawn and implications for future research are discussed

Effect of magnetic and non-magnetic impurities on highly anisotropic superconductivity

We generalize Abrikosov-Gor'kov solution of the problem of weakly coupled superconductor with impurities on the case of a multiband superconductor with arbitrary interband order parameter anisotropy, including interband sign reversal of the order parameter. The solution is given in terms of the effective (renormalized) coupling matrix and describes not only $T_c$ suppression but also renormalization of the superconducting gap basically at all temperatures. In many limiting cases we find analytical solutions for the critical temperature suppression. We illustrate our results by numerical calculations for two-band model systems.Comment: 18 pages (12pt) RevTeX, 4 postscript figure