METAPOETIC REFLECTIONS IN THREE AETIA OF THE ARGONAUTICA

This article studies three aetia in the Argonautica that have metapoetic significance as comments on Apollonius’ Callimachean poetics. In the first aetion (1.1132–1139), the Pyrrhic dance reflects the Argonauts’ key role as active agents in the creation of the plot and shows its Callimachean allegiance in the repurposing of traditional martial imagery. In the second one (4.1719–1730), the meagerness of the Argonauts’ offering to Apollo at Anaphe and the light jesting between Medea’s maidens and the Argonauts are programmatic reflections of the ‘lean’ poetics advocated by Callimachus in the Aetia ‘prologue’ (fr. 1). The third aetion (4.1765–1772), by closing the Argonautica in correspondence with the beginning of Callimachus’ Aetia, stresses the close connection between Apollonius and Callimachus. In it, the quick pace, lightness and playfulness of the hydrophoria at Aegina mirrors the fast coming to an end and happy tone that closes the Argonautica

Buffering plasmons in nanoparticle waveguides at the virtual-localized transition

We study the plasmonic energy transfer from a locally excited nanoparticle (LE-NP) to a linear array of small NPs and we obtain the parametric dependence of the response function. An analytical expression allows us to distinguish the extended resonant states and the localized ones, as well as an elusive regime of virtual states. This last appears when the resonance width collapses and before it becomes a localized state. Contrary to common wisdom, the highest excitation transfer does not occur when the system has a well defined extended resonant state but just at the virtual-localized transition, where the main plasmonic modes have eigenfrequencies at the passband edge. The slow group velocity at this critical frequency enables the excitation buffering and hence favors a strong signal inside the chain. A similar situation should appear in many other physical systems. The extreme sensitivity of this transition to the waveguide and LE-NP parameters provides new tools for plasmonics.Comment: Regular article: 7 pages and 5 figure

Studies on erythrocyte aminolaevulinate dehydratase I. Its purification and possible therapeutic applications

1. 1. A method for purifying human erythrocytes ALA-D, using a mixture of n-butanol and chloroform, which denature hemoglobin, followed by ammonium sulphate fractionation and affinity chromatography yielding a 1600-fold purified enzyme, is described. 2. 2. By oxidation of Sephadex G-25 with NaIO4, a polyaldehyde, is obtained which can be covalently bound to the ALA-D; however the immobilized enzyme is inactive, because essential ε{lunate}-amino groups at the active site were involved in the coupling. Similar experiments with another enzyme, Rhodanese, resulted in an active insolubilized preparation. 3. 3. By suspending the carrier-enzyme in buffer, slow solubilization with simultaneous release of protein occurs, indicating that this approach might find important therapeutical applications in the treatment of enzyme deficiencies. © 1980.Fil:Bustos, N. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.Fil:Stella, A.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.Fil:C. Batlle, A.M.D. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina

Editorial

This guest-edited Special Issue of RERM celebrates the enormous contribution that Professor Jeanette Rhedding-Jones made to the field of educational research over her life time

La representaci?n esc?nica de obras literarias para desarrollar la comprensi?n lectora de ni?os de cuarto de primaria del Colegio Carlos Lozano y Lozano de Fusagasug? Cundinamarca

143 p. Recurso Electr?nicoEsta investigaci?n surge de la observaci?n realizada en la instituci?n Carlos lozano y lozano ubicado en el municipio de Fusagasug? Cundinamarca en el grado cuarto a partir de las falencias encontradas sobre la comprensi?n lectora, en cuanto a las dificultades para reconocer lo impl?cito del texto, ya que solamente se identifica lo expl?cito sin interiorizar el sentido que el autor le quiere dar a su escrito. El objetivo de este trabajo fue Fortalecer mediante la representaci?n esc?nica de obras literarias la compresi?n lectora para crear h?bitos de lectura que permitieron generar en los estudiantes sus propios escritos para luego ser representados. Para ello se tuvo en cuenta investigaciones realizadas donde se aplic? la estrategia did?ctica del teatro para fortalecer la competencia comunicativa, las habilidades de oralidad, las inteligencias m?ltiples de manera din?mica y l?dica que permiten desarrollar el inter?s y la motivaci?n en el proceso de ense?anza aprendizaje. La investigaci?n se fundament? en te?ricos como Loaiza (2011), Pavis (1983), Moreno (1993), sol? (1992), Ni?o (1985), Ferreiro y Teberosky (1991), Vygotsky (1997), Piaget (1952) y Ausubel (1983), que con sus estudios de la comprensi?n lectora, la lectura, la escritura y el teatro permitieron el desarrollo metodol?gico y el an?lisis de resultado al sustentar los procesos l?gicos- secuenciales de esta propuesta. Para el proceso metodol?gico se realizaron ocho talleres divididos en cuatro fases sensibilizaci?n, conocimientos previos, profundizaci?n y transferencia. Desde el enfoque significativo y el IAP, mediante su aplicaci?n se logr? mejorar la comprensi?n lectora por medio de la representaci?n de obras literarias.This research arises of the observation developed in the Carlos Lozano and Lozano institution located in the municipality of Fusagasuga Cundinamarca in the fourth degree due to failures found in reading comprehension, as to the difficulties to recognize the implicit of the text, since only the explicit is identified without internalizing the meaning that the author wants to give to his writing. The objective of this project was to strengthen reading comprehension through of scenic representation of literary works to create habits of reading that allowed to the students to generate their own writings for then be represented. For that took into account researches where the didactic strategy of the theater was applied to strengthen communicative competence, orality skills, multiple intelligences in a dynamic and playful way that allow to develop interest and motivation in the teaching-learning process. The research was based in theoreticians as Loaiza (2011), Pavis (1983), Moreno (1993), sol? (1992), Ni?o (1985), Ferreiro y Teberosky (1991), Vygotsky (1997), Piaget (1952) and Ausubel (1983), that with their studies of the reading comprehension, the reading, the writing and the theater allowed the methodological development and the analysis of results in supporting the logical-sequential processes of this proposal. For the methodological process, there were eight activities divided in four stages: sensitization, previous knowledge, deepening and transference. From the significant approach and the PAI, through its application it was possible to improve the reading comprehension through the representation of literary works. Keywords: Reading, reading comprehension, writing, theater, education

Technological Change and the Finance Wage Premium

This paper utilizes a comprehensive worker-firm panel for the Netherlands to quantify the impact of ICT capital-skill complementarity on the finance wage premium after the Global Financial Crisis. We apply additive worker and firm fixed-effect models to account for unobserved worker- and firm-heterogeneity and show that firm fixed-effects correct for a downward bias in the estimated finance wage premium. Our results indicate a sizable finance wage premium for both fixed- and full-hourly wages. The complementarity between ICT capital spending and the share of high skill workers at the firm-level reduces the full-wage premium considerably and the fixed-wage premium almost entirely

Simulating residential electricity and heat demand in urban areas using an agent-based modelling approach

Cities account for around 75% of the global energy demand and are responsible for 60-70% of the global greenhouse gasses emissions. To reduce this environmental impact it is important to design efficient energy infrastructures able to deal with high level of renewable energy resources. A crucial element in this design is the quantitative understanding of the dynamics behind energy demands such as transport, electricity and heat. In this paper an agent-based simulation model is developed to generate residential energy demand profiles in urban areas, influenced by factors such as land use, energy infrastructure and user behaviour. Within this framework, impact assessment of low carbon technologies such as plug-in electric vehicles and heat pumps is performed using London as a case study. The results show that the model can generate important insights as a decision support tool for the design and planning of sustainable urban energy systems

Yard-Sale exchange on networks: Wealth sharing and wealth appropriation

Yard-Sale (YS) is a stochastic multiplicative wealth-exchange model with two phases: a stable one where wealth is shared, and an unstable one where wealth condenses onto one agent. YS is here studied numerically on 1d rings, 2d square lattices, and random graphs with variable average coordination, comparing its properties with those in mean field (MF). Equilibrium properties in the stable phase are almost unaffected by the introduction of a network. Measurement of decorrelation times in the stable phase allow us to determine the critical interface with very good precision, and it turns out to be the same, for all networks analyzed, as the one that can be analytically derived in MF. In the unstable phase, on the other hand, dynamical as well as asymptotic properties are strongly network-dependent. Wealth no longer condenses on a single agent, as in MF, but onto an extensive set of agents, the properties of which depend on the network. Connections with previous studies of coalescence of immobile reactants are discussed, and their analytic predictions are successfully compared with our numerical results.Comment: 10 pages, 7 figures. Submitted to JSTA

α-SNAP Prevents Docking of the Acrosome during Sperm Exocytosis because It Sequesters Monomeric Syntaxin

α-SNAP has an essential role in membrane fusion that consists of bridging cis SNARE complexes to NSF. α-SNAP stimulates NSF, which releases itself, α-SNAP, and individual SNAREs that subsequently re-engage in the trans arrays indispensable for fusion. α-SNAP also binds monomeric syntaxin and NSF disengages the α-SNAP/syntaxin dimer. Here, we examine why recombinant α-SNAP blocks secretion in permeabilized human sperm despite the fact that the endogenous protein is essential for membrane fusion. The only mammalian organism with a genetically modified α-SNAP is the hyh mouse strain, which bears a M105I point mutation; males are subfertile due to defective sperm exocytosis. We report here that recombinant α-SNAP-M105I has greater affinity for the cytosolic portion of immunoprecipitated syntaxin than the wild type protein and in consequence NSF is less efficient in releasing the mutant. α-SNAP-M105I is a more potent sperm exocytosis blocker than the wild type and requires higher concentrations of NSF to rescue its effect. Unlike other fusion scenarios where SNAREs are subjected to an assembly/disassembly cycle, the fusion machinery in sperm is tuned so that SNAREs progress uni-directionally from a cis configuration in resting cells to monomeric and subsequently trans arrays in cells challenged with exocytosis inducers. By means of functional and indirect immunofluorescense assays, we show that recombinant α-SNAPs — wild type and M105I — inhibit exocytosis because they bind monomeric syntaxin and prevent this SNARE from assembling with its cognates in trans. Sequestration of free syntaxin impedes docking of the acrosome to the plasma membrane assessed by transmission electron microscopy. The N-terminal deletion mutant α-SNAP-(160–295), unable to bind syntaxin, affects neither docking nor secretion. The implications of this study are twofold: our findings explain the fertility defect of hyh mice and indicate that assembly of SNAREs in trans complexes is essential for docking

Relationships in Patagonian species of Berberis (Berberidaceae) based on the characterization of rDNA internal transcribed spacer sequences

Sequence analysis of the internal transcribed spacer (ITS) of the 18S(ITS1)-5.8S 26S(ITS2) rDNA region was performed in order to analyse the phylogenetic relationships between 13 Patagonian species of the genus Berberis (Berberidaceae). The divergence values between the pairwise sequence in the studied Patagonian species were in the range 2.9–22.9%. The lengths of the ITS1 and ITS2 sequences were in the range 227–231 bp and 220–224 bp, respectively, and the 5.8S sequence was 159 bp throughout all species. B. microphylla sensu Landrum does not appear to be monophyletic based on current sampling. Indeed, we suggest that B. microphylla should be distinguished from B. buxifolia, B. parodii, and B. heterophylla . ITS sequences, together with data obtained from morphological, biochemical, amplified fragment length polymorphism, and cytological characterizations, support the existence of diploid and polyploid hybrid speciation in the genus.Fil: Bottini, Maria Cecilia Juana. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Austral de Chile; ChileFil: de Bustos, A.. Universidad de Alcalá; EspañaFil: Sanso, Andrea Mariel. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Jouve, N.. Universidad de Alcalá; EspañaFil: Poggio, Lidia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentin