125 research outputs found
Mesure des enthalpies de solution du CO2 dans les solutions aqueuses d'alcanolamines primaires aux trĂšs faibles taux de charge
National audienceLa dĂ©termination des enthalpies de solution des gaz, en particulier CO 2 et H 2 S, dans les solutions aqueuses d'alcanolamines a permis d'obtenir de nombreuses donnĂ©es pour alimenter les modĂšles thermodynamiques et amĂ©liorer les procĂ©dĂ©s de captage de ces gaz dans les fumĂ©es industrielles. Cependant le dispositif utilisĂ© jusqu'alors ne permettait pas d'obtenir des rĂ©sultats fiables pour les faibles taux de charge en gaz ( infĂ©rieur Ă 0.2). Les chaleurs de solution de CO 2 dans les solutions aqueuses d'amine ont Ă©tĂ© obtenues en utilisant un calorimeter BT2.15 de type calvet de la sociĂ©tĂ© SETARAM. Les cellules utilisĂ©es pour rĂ©aliser le mĂ©lange sont des cellules Ă Ă©coulement dĂ©veloppĂ©es au laboratoire. Lors de la mesure, les deux fluides, respectivement le gaz et la solution aqueuse, sont injectĂ©s dans la cellule de mĂ©lange Ă l'aide de deux pompes seringues haute pression (ISCO), Ă tempĂ©rature et Ă pression constantes. L'enthalpie de solution est obtenue Ă partir de la diffĂ©rence entre le flux thermique mesurĂ© par les thermopiles lors du mĂ©lange et celui obtenu lorsque la solution aqueuse circule dans le calorimĂštre sans CO 2. En faisant varier le dĂ©bit des pompes, il est possible de dĂ©terminer l'enthalpie pour diffĂ©rents taux de charge en CO 2 (, en mol CO 2 / mol Amine). Cependant, les dĂ©bits respectifs de gaz et de liquide qui doivent ĂȘtre utilisĂ©s pour mesurer l'enthalpie de solution pour des taux de charge infĂ©rieurs Ă 0.2 sont extrĂȘmement diffĂ©rents et le dĂ©bit de liquide trop important pour pouvoir rĂ©aliser la mesure. Afin de rĂ©duire cette diffĂ©rence entre les dĂ©bits, nous remplacĂ© le CO 2 pur par des mĂ©langes de gaz (CO 2-N 2) de composition connue. L'azote n'Ă©tant pas soluble dans la solution aqueuse d'amine, l'effet thermique obtenu lors du mĂ©lange est alors directement liĂ© Ă l'enthalpie de dissolution du CO 2. L'azote est alors considĂ©rĂ© comme un gaz de dilution du CO 2. Un exemple est prĂ©sentĂ© ici pour les systĂšmes aqueux contenant de la monoĂ©thanolamine (MEA) ou de l'aminomĂ©thylpropanol (AMP), ou un mĂ©lange des deux amines. Les rĂ©sultats obtenus sont en trĂšs bon accord avec ceux obtenus pour les mesures avec du CO2 pur
Effect of Quinoa Seeds (Chenopodium quinoa) in Diet on some Biochemical Parameters and Essential Elements in Blood of High Fructose-Fed Rats
The effect of Chenopodium quinoa seeds on lipid profile, glucose level, protein metabolism and selected essential elements (Na, K, Ca, Mg) level was determined in highâfructose fed male Wistar rats. Fructose decreased significantly LDL [42%, pâ<â0.01] and activity of alkaline phosphatase [20%, pâ<â0.05], and increased triglycerides level [86%, pâ<â0.01]. The analysis of blood of rats fed quinoa indicated, that these seeds effectively reduced serum total cholesterol [26%, pâ<â0.05], LDL [57%, pâ<â0.008] and triglycerides [11%, pâ<â0.05] when compared to the control group. Quinoa seeds also significantly reduced the level of glucose [10%, pâ<â0.01] and plasma total protein level [16%, pâ<â0.001]. Fructose significantly decreased HDL [15%, pâ<â0.05] level in control group but when the quinoa seeds were added into the diet the decrease of HDL level was inhibited. Quinoa seeds did not prevent any adverse effect of increasing triglyceride level caused by fructose. It was shown in this study that quinoa seeds can reduce most of the adverse effects exerted by fructose on lipid profile and glucose level
Gut microbiota-derived propionate reduces cancer cell proliferation in the liver
Peer reviewedPublisher PD
Nuclear translocation of haeme oxygenase-1 is associated to prostate cancer
The role of oxidative stress in prostate cancer has been increasingly recognised. Acute and chronic inflammations generate reactive oxygen species that result in damage to cellular structures. Haeme oxygenase-1 (HO-1) has cytoprotective effects against oxidative damage. We hypothesise that modulation of HO-1 expression may be involved in the process of prostate carcinogenesis and prostate cancer progression. We thus studied HO-1 expression and localisation in 85 samples of organ-confined primary prostate cancer obtained via radical prostatectomy (Gleason grades 4â9) and in 39 specimens of benign prostatic hyperplasia (BPH). We assessed HO-1 expression by immunohistochemical staining. No significant difference was observed in the cytoplasmic positive reactivity among tumours (84%), non-neoplastic surrounding parenchyma (89%), or BPH samples (87%) (P=0.53). Haeme oxygenase-1 immunostaining was detected in the nuclei of prostate cancer cells in 55 of 85 (65%) patients but less often in non-neoplastic surrounding parenchyma (30 of 85, 35%) or in BPH (9 of 39, 23%) (P<0.0001). Immunocytochemical and western blot analysis showed HO-1 only in the cytoplasmic compartment of PC3 and LNCaP prostate cancer cell lines. Treatment with hemin, a well-known specific inducer of HO-1, led to clear nuclear localisation of HO-1 in both cell lines and highly induced HO-1 expression in both cellular compartments. These findings have demonstrated, for the first time, that HO-1 expression and nuclear localisation can define a new subgroup of prostate cancer primary tumours and that the modulation of HO-1 expression and its nuclear translocation could represent new avenues for therapy
Fructo-oligosaccharides and glucose homeostasis: a systematic review and meta-analysis in animal models
Honey, a Gift from Nature to Health and Beauty: A Review
Benefits of honey are contributed by the composition of its elements such as glucose, fructose, glucose oxidase, vitamins and phenolic compounds. For health, honey can be used to treat wounds due to the antibacterial activity conferred by the hydrogen peroxide produced by glucose oxidase in honey. Anti-inflammatory, anti-oxidant, deodorizing and tissue regeneration activities in honey also help in the wound healing process. It can also be an alternative sweetener for diabetic patients to ensure compliance to a healthy diet. Moreover, honey exerts several effects such as lowering low density lipids and increasing high density lipids, thus reducing risk of atherosclerosis. In terms of beauty, honey can be used on skin and hair. It moisturizes skin through its natural humectant properties contributed by high contents of fructose and glucose. Honey treats acne on the skin due to its antibacterial activity, anti-inflammatory action and tissue repair. The hair can benefit from honey in such a way that the hair has abundance, and becomes easier to comb. However, there have not been as many studies regarding the use of honey in skin in comparison to its use for health. Therefore, future studies on honey could research its use, action and benefits in both cosmetics and dermatology
Cobalt protoporphyrin represses osteoclastogenesis through blocking multiple signaling pathways
Cobalt protoporphyrin (CoPP) is a metallo-protoporphyrin that works as a powerful inducer of heme oxigenase-1 (HO-1) in various tissues and cells. Our recent studies have demonstrated that induction of HO-1 by several reagents inhibited differentiation and activation of osteoclasts (OCLs), which are multinucleated bone resorbing cells. However, the effects of CoPP on osteoclastogenesis remain to be elucidated. In this study, we report that CoPP inhibits receptor activator of nuclear factor ÎșB ligand (RANKL)-induced OCL formation in a dose dependent manner. Importantly, CoPP had little cytotoxicity, but rather enhanced cell proliferation of OCLs. CoPP suppressed the protein levels of nuclear factor of activated T cells cytoplasmic-1 (NFATc1) as well as those of OCLs markers such as Src and cathepsin K, which are transcriptionally regulated by NFATc1 in mature OCLs. Western blot analyses also showed that CoPP abolished RANKL-stimulated phosphorylation of several major signaling pathways such as IÎșB, Akt, ERK, JNK and p38 MAPKs in OCL precursor cells. Thus, our results show that CoPP represses osteoclastogenesis through blocking multiple signaling pathways
Ecology and biogeography of megafauna and macrofauna at the first known deep-sea hydrothermal vents on the ultraslow-spreading Southwest Indian Ridge
0000-0002-9489-074X© The Author(s) 2016. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the articleâs Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ The attached file is the published version of the article
Pathogenesis of Cardiovascular and Metabolic Diseases: Are Fructose-Containing Sugars More Involved Than Other Dietary Calories?
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