898 research outputs found

    Cloning and sequencing of the cDNA encoding for a Na+/H+ exchanger from Xenopus laevis oocytes (Xl-NHE)1The nucleotide sequence reported in this paper has been submitted to the EMBL, GenBank and DDBJ NucleotideSequence Database under the Accession number Y08635.1

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    AbstractWe have cloned and sequenced the cDNA for a Na+/H+ exchanger (NHE) from Xenopus laevis oocytes. This cDNA contains an open reading frame encoding a protein of 782 amino acids with 12 putative transmembrane domains and a long cytoplasmic tail. The protein exhibits a strong homology at the amino acid level to the human NHE-1 as well as to the βNHE from trout red blood cells: 69% and 58% respectively. Two potential N-linked glycosylation sites at Asn56 and Asn351 were identified. Three potential protein kinase C phosphorylation sites at the cytoplasmic tail were identified at Ser494, Thr726 and Ser747. RT-PCR revealed the expression of the Xl-NHE in Xenopus heart, reticulocytes and skeletal muscle. Š 1997 Elsevier Science B.V. All rights reserved

    A near-field study on the transition from localized to propagating plasmons on 2D nano-wedges

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    In this manuscript we report on a near-feld study of two-dimensional plasmonic gold nano-wedges using electron energy loss spectroscopy in combination with scanning transmission electron microscopy, as well as discontinuous Galerkin time-domain computations. With increasing nano-wedge size, we observe a transition from localized surface plasmons on small nano-wedges to non-resonant propagating surface plasmon polaritons on large nano-wedges. Furthermore we demonstrate that nano-wedges with a groove cut can support localized as well as propagating plasmons in the same energy range

    Onwards and upwards: European Journal of Medical Research continues as an open access publication

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    The well-established European Journal of Medical Research has joined BioMed Central's portfolio of journals in January 2012, converting to the open access publishing model. Since its launch in 1995 the journal has been a print-only publication; from now on, it continues as an open access, online-only journal. The conversion to open access opens up the potential for the journal to become a leading, globally visible title in the field of general medicine over the coming years

    Update on Acute Hemorrhagic Diarrhea Syndrome in Dogs

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    Attraction: Transnational Municipal Climate Networks and Green City Branding

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    Abstract In this article, we investigate the nexus of green city branding and municipal climate networks. In recent decades, a number of formal transnational municipal climate networks have emerged and their membership continues to increase. In parallel, city branding that is based on green policies, has gained importance. Based on quantitative and qualitative data, we assess how and to what extent German cities use their membership in transnational municipal climate networks to communicate green city brands. In contrast to our expectations, we encountered very few indications of green city branding efforts by German cities. Our analysis shows that in general, branding considerations only play a negligible role in the involvement of cities in transnational municipal climate networks or climate policies. Instead, it seems that German cities use their membership in climate networks, to genuinely improve local climate change strategies. We therefore suggest that research on green city branding should be more sensitive to the particular context of cities and efforts should be made to unveil the underlying motives for the communication of green policies

    A statistical MMN reflects the magnitude of transitional probabilities in auditory sequences

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    Within the framework of statistical learning, many behavioural studies investigated the processing of unpredicted events. However, surprisingly few neurophysiological studies are available on this topic, and no statistical learning experiment has investigated electroencephalographic (EEG) correlates of processing events with different transition probabilities. We carried out an EEG study with a novel variant of the established statistical learning paradigm. Timbres were presented in isochronous sequences of triplets. The first two sounds of all triplets were equiprobable, while the third sound occurred with either low (10%), intermediate (30%), or high (60%) probability. Thus, the occurrence probability of the third item of each triplet (given the first two items) was varied. Compared to high-probability triplet endings, endings with low and intermediate probability elicited an early anterior negativity that had an onset around 100 ms and was maximal at around 180 ms. This effect was larger for events with low than for events with intermediate probability. Our results reveal that, when predictions are based on statistical learning, events that do not match a prediction evoke an early anterior negativity, with the amplitude of this mismatch response being inversely related to the probability of such events. Thus, we report a statistical mismatch negativity (sMMN) that reflects statistical learning of transitional probability distributions that go beyond auditory sensory memory capabilities

    Lueders Theorem for Coherent-State POVMs

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    Lueders theorem states that two observables commute if measuring one of them does not disturb the measurement outcomes of the other. We study measurements which are described by continuous positive operator-valued measurements (or POVMs) associated with coherent states on a Lie group. In general, operators turn out to be invariant under the Lueders map if their P- and Q-symbols coincide. For a spin corresponding to SU(2), the identity is shown to be the only operator with this property. For a particle, a countable family of linearly independent operators is identified which are invariant under the Lueders map generated by the coherent states of the Heisenberg-Weyl group, H_3. The Lueders map is also shown to implement the anti-normal ordering of creation and annihilation operators of a particle.Comment: 14 pages, no figure

    Influence of process gas during powder bed fusion with laser beam of Zr-based bulk metallic glasses

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    Zr-based bulk metallic glasses offer a unique combination of hardness, high strength, and high elastic limits. Yet, manufacturable size and complexity are limited due to the required cooling rates. Short laser-material interaction times together with layer-wise and selective energy input allows the laser powder bed fusion process to largely overcome those restrictions. Still, the complex process-material interactions inhere numerous uncertainties. In the present work, additively manufactured Zr-based bulk metallic glasses produced under three different process gases are investigated by calorimetry, x-ray diffraction, and bending tests. A strong dependence between the thermophysical properties, flexural strength, and the applied atmosphere is found
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