Preliminary Results from Striped Bass Tagging in Virginia, 1968-1969

A total of 8525 striped bass, Morone saxatilis (Walbaum), were tagged and released in Virginia during 1968 and 1969. Releases were grouped in three periods: (1) 3195 in winter 1968, (2) 2439 during summer-fall 1968; and (3) 2891 in winter 1969. Streamer disc tags, employed in winter 1968, were subsequently replaced by internal anchor tags (Floy Tag No. FD-67). This substitution shortened application time and eliminated a source of bias introduced by the entanglement of disc tags in gill nets. Releases were made in the James, York, and Rappahannock rivers in all three periods. Rewards of one dollar have been paid for return of tags. Percentages of returns within tagged year-classes increased with age, indicating change in fishing mortality rates of striped bass during their initial 3 to 4-year residence in the lower Chesapeake Bay system.https://scholarworks.wm.edu/vimsbooks/1106/thumbnail.jp

Everyday cosmopolitanism in representations of Europe among young Romanians in Britain

The paper presents an analysis of everyday cosmopolitanism in constructions of Europe among young Romanian nationals living in Britain. Adopting a social representations approach, cosmopolitanism is understood as a cultural symbolic resource that is part of everyday knowledge. Through a discursively-oriented analysis of focus group data, we explore the ways in which notions of cosmopolitanism intersect with images of Europeanness in the accounts of participants. We show that, for our participants, representations of Europe are anchored in an Orientalist schema of West-vs.-East, whereby the West is seen as epitomising European values of modernity and progress, while the East is seen as backward and traditional. Our findings further show that representations of cosmopolitanism reinforce this East/West dichotomy, within a discourse of ‘Occidental cosmopolitanism’. The paper concludes with a critical discussion of the diverse and complex ideological foundations of these constructions of European cosmopolitanism and their implications

Apraxia and motor dysfunction in corticobasal syndrome

Background: Corticobasal syndrome (CBS) is characterized by multifaceted motor system dysfunction and cognitive disturbance; distinctive clinical features include limb apraxia and visuospatial dysfunction. Transcranial magnetic stimulation (TMS) has been used to study motor system dysfunction in CBS, but the relationship of TMS parameters to clinical features has not been studied. The present study explored several hypotheses; firstly, that limb apraxia may be partly due to visuospatial impairment in CBS. Secondly, that motor system dysfunction can be demonstrated in CBS, using threshold-tracking TMS, and is linked to limb apraxia. Finally, that atrophy of the primary motor cortex, studied using voxel-based morphometry analysis (VBM), is associated with motor system dysfunction and limb apraxia in CBS.   Methods: Imitation of meaningful and meaningless hand gestures was graded to assess limb apraxia, while cognitive performance was assessed using the Addenbrooke's Cognitive Examination - Revised (ACE-R), with particular emphasis placed on the visuospatial subtask. Patients underwent TMS, to assess cortical function, and VBM.   Results: In total, 17 patients with CBS (7 male, 10 female; mean age 64.4+/2 6.6 years) were studied and compared to 17 matched control subjects. Of the CBS patients, 23.5% had a relatively inexcitable motor cortex, with evidence of cortical dysfunction in the remaining 76.5% patients. Reduced resting motor threshold, and visuospatial performance, correlated with limb apraxia. Patients with a resting motor threshold <50% performed significantly worse on the visuospatial sub-task of the ACE-R than other CBS patients. Cortical function correlated with atrophy of the primary and pre-motor cortices, and the thalamus, while apraxia correlated with atrophy of the pre-motor and parietal cortices.   Conclusions: Cortical dysfunction appears to underlie the core clinical features of CBS, and is associated with atrophy of the primary motor and pre-motor cortices, as well as the thalamus, while apraxia correlates with pre-motor and parietal atrophy

Cascade oxime formation, cyclization to a nitrone, and intermolecular dipolar cycloaddition.

Simple haloaldehydes, including enolisable aldehydes, were found to be suitable for the formation of cyclic products by cascade (domino) condensation, cyclisation, dipolar cycloaddition chemistry. This multi-component reaction approach to heterocyclic compounds was explored by using hydroxylamine, a selection of aldehydes, and a selection of activated dipolarophiles. Initial condensation gives intermediate oximes that undergo cyclisation with displacement of halide to give intermediate nitrones; these nitrones undergo in situ intermolecular dipolar cycloaddition reactions to give isoxazolidines. The cycloadducts from using dimethyl fumarate were treated with zinc/acetic acid to give lactam products and this provides an easy way to prepare pyrrolizinones, indolizinones, and pyrrolo[2,1-a]isoquinolinones. The chemistry is illustrated with a very short synthesis of the pyrrolizidine alkaloid macronecine and a formal synthesis of petasinecine

An index to quantify an individual's scientific research output that takes into account the effect of multiple coauthorship

I propose the index $\hbar$ ("hbar"), defined as the number of papers of an individual that have citation count larger than or equal to the $\hbar$ of all coauthors of each paper, as a useful index to characterize the scientific output of a researcher that takes into account the effect of multiple coauthorship. The bar is higher for $\hbar$.Comment: A few minor changes from v1. To be published in Scientometric

Zonal flows and long-distance correlations during the formation of the edge shear layer in the TJ-II stellarator

A theoretical interpretation is given for the observed long-distance correlations in potential fluctuations in TJ-II. The value of the correlation increases above the critical point of the transition for the emergence of the plasma edge shear flow layer. Mean (i.e. surface averaged, zero-frequency) sheared flows cannot account for the experimental results. A model consisting of four envelope equations for the fluctuation level, the mean flow shear, the zonal flow amplitude shear, and the averaged pressure gradient is proposed. It is shown that the presence of zonal flows is essential to reproduce the main features of the experimental observations.Comment: 19 pages, 7 figure

Heterogeneity in Multiple Sclerosis: Scratching the Surface of a Complex Disease

Multiple Sclerosis (MS) is the most common demyelinating disease of the central nervous system. Although the etiology and the pathogenesis of MS has been extensively investigated, no single pathway, reliable biomarker, diagnostic test, or specific treatment have yet been identified for all MS patients. One of the reasons behind this failure is likely to be the wide heterogeneity observed within the MS population. The clinical course of MS is highly variable and includes several subcategories and variants. Moreover, apart from the well-established association with the HLA-class II DRB1*15:01 allele, other genetic variants have been shown to vary significantly across different populations and individuals. Finally both pathological and immunological studies suggest that different pathways may be active in different MS patients. We conclude that these “MS subtypes” should still be considered as part of the same disease but hypothesize that spatiotemporal effects of genetic and environmental agents differentially influence MS course. These considerations are extremely relevant, as outcome prediction and personalised medicine represent the central aim of modern research

Characterization of density fluctuations during the search for an I-mode regime on the DIII-D tokamak

The I-mode regime, routinely observed on the Alcator C-Mod tokamak, is characterized by an edge energy transport barrier without an accompanying particle barrier and with broadband instabilities, known as weakly coherent modes (WCM), believed to regulate particle transport at the edge. Recent experiments on the DIII-D tokamak exhibit I-mode characteristics in various physical quantities. These DIII-D plasmas evolve over long periods, lasting several energy confinement times, during which the edge electron temperature slowly evolves towards an H-mode-like profile, while maintaining a typical L-mode edge density profile. During these periods, referred to as I-mode phases, the radial electric field at the edge also gradually reaches values typically observed in H-mode. Density fluctuations measured with the phase contrast imaging diagnostic during I-mode phases exhibit three features typically observed in H-mode on DIII-D, although they develop progressively with time and without a sharp transition: the intensity of the fluctuations is reduced; the frequency spectrum is broadened and becomes non-monotonic; two dimensional space-time spectra appear to approach those in H-mode, showing phase velocities of density fluctuations at the edge increasing to about 10 km s−1. However, in DIII-D there is no clear evidence of the WCM. Preliminary linear gyro-kinetic simulations are performed in the pedestal region with the GS2 code and its recently upgraded model collision operator that conserves particles, energy and momentum. The increased bootstrap current and flow shear generated by the temperature pedestal are shown to decrease growth rates, thus possibly generating a feedback mechanism that progressively stabilizes fluctuations.United States. Department of Energy. Office of Fusion Energy Sciences (Award DE-FG02- 94ER54235)United States. Department of Energy. Office of Fusion Energy Sciences (Award DE-FG02-94ER54084)United States. Department of Energy. Office of Fusion Energy Sciences (Award DE-FG02-08ER54984)United States. Department of Energy. Office of Fusion Energy Sciences (Award DE-FC02-04ER54698