Let\u27s Talk About Ethics! A Qualitative Analysis of First-year Engineering Student Group Discussions Around Ethical Scenarios

Over the past decade, there has been a renewed interest in the scope and practice of ethics education in engineering curricula, especially in the first year. However, the form this education takes has varied considerably with each program. Active learning strategies such as discussions on ethical and societal issues have become increasingly common for assessing how students make ethical decisions. But probing the depths of the reasoning behind their decisions and how students discuss ethics in context with their peers has been under-studied and difficult. Furthermore, if first-year programs wish to implement effective instructional interventions aimed at improving ethical decision making skills, pre-assessment of student thought processes is required. This full research paper offers findings from the first phase of a multi-university research project, aimed at investigating the impact game-based instruction can have on the development of engineering students’ ethical awareness and decision making. Specifically, the research presented in this paper is guided by the following research question: How do engineering students reason through engineering-ethical scenarios prior to college-level ethics education? First-year engineering students across three universities in the northeast USA will participate in group discussions around engineering ethical scenarios derived from the Engineering Ethics Reasoning Instrument (EERI) and Toxic Workplaces: A Cooperative Ethics Card Game (developed by the researchers). The questions posed to the student groups center around primary morality concepts such as integrity, conflicting obligations, and the contextual nature of ethical decision making. An a priori coding schema based on these concepts will be utilized, along with an inductive thematic analysis to tease out emergent themes. Results from this research will provide insight into how first-year engineering students think and discuss ethics prior to formal instruction, which can inform curricular design and development strategy. The research also provides a curated series of ethical engineering scenarios with accompanying discussion questions that can be adopted in any first-year classroom for instructional and evaluative purposes

Feasibility study of a family- and school-based intervention for child behavior problems in Nepal.

Background: This study evaluates the feasibility, acceptability, and outcomes of a combined school- and family-based intervention, delivered by psychosocial counselors, for children with behavior problems in rural Nepal. Methods: Forty-one children participated at baseline. Two students moved to another district, meaning 39 children, ages 6-15, participated at both baseline and follow-up. Pre-post evaluation was used to assess behavioral changes over a 4-month follow-up period (n = 39). The primary outcome measure was the Disruptive Behavior International Scale-Nepal version (DBIS-N). The secondary outcome scales included the Child Functional Impairment Scale and the Eyberg Child Behavior Inventory (ECBI). Twelve key informant interviews were conducted with community stakeholders, including teachers, parents, and community members, to assess stakeholders\u27 perceptions of the intervention. Results: The study found that children\u27s behavior problems as assessed on the DBIS-N were significantly lower at follow-up (M = 13.0, SD = 6.4) than at baseline (M = 20.5, SD = 3.8), p \u3c 0.001, CI [5.57, 9.35]. Similarly, children\u27s ECBI Intensity scores were significantly lower at follow-up (M = 9.9, SD = 8.5) than at baseline (M = 14.8, SD = 7.7), p \u3c 0.005, 95% CI [1.76, 8.14]. The intervention also significantly improved children\u27s daily functioning. Parents and teachers involved in the intervention found it acceptable and feasible for delivery to their children and students. Parents and teachers reported improved behaviors among children and the implementation of new behavior management techniques both at home and in the classroom. Conclusions: Significant change in child outcome measures in this uncontrolled evaluation, alongside qualitative findings suggesting feasibility and acceptability, support moving toward a controlled trial to determine effectiveness

Beta-delayed-neutron studies of 135,136^{135,136}Sb and 140^{140}I performed with trapped ions

Beta-delayed-neutron ($\beta$n) spectroscopy was performed using the Beta-decay Paul Trap and an array of radiation detectors. The $\beta$n branching ratios and energy spectra for $^{135,136}$Sb and $^{140}$I were obtained by measuring the time of flight of recoil ions emerging from the trapped ion cloud. These nuclei are located at the edge of an isotopic region identified as having $\beta$n branching ratios that impact the r-process abundance pattern around the A~130 peak. For $^{135,136}$Sb and $^{140}$I, $\beta$n branching ratios of 14.6(11)%, 17.6(28)%, and 7.6(28)% were determined, respectively. The $\beta$n energy spectra obtained for $^{135}$Sb and $^{140}$I are compared with results from direct neutron measurements, and the $\beta$n energy spectrum for $^{136}$Sb has been measured for the first time

Influence of L-carnitine on litter characteristics from gilts harvested at day 40, 55, and 70 of gestation

Swine research, 2005 is known as Swine day, 2005A total of 59 gilts were used to determine the effects of supplemental L-carnitine on reproductive performance. Experimental treatments were arranged in a 2 × 3 factorial with main effects of L-carnitine (0 or 50 ppm) and day of gestation (40, 55, or 70). All gilts received a constant feed allowance of 3.86 lb/day and a top-dress containing either 0 or 88 mg of L-carnitine, starting on the first day of breeding and continuing until the day of harvest. Total litter size, total litter weight, and crown-to-rump length of fetuses were not different (P>0.10) between treatments at any gestation length. By d 70 of gestation, average fetus weight was heavier (P = 0.06) for fetuses from gilts fed L-carnitine, compared with fetuses from gilts fed the control diet. In addition, at d 70, fetal insulin-like growth factor- II (IGF-II) concentrations were lower (P = 0.09) for fetuses from gilts fed L-carnitine than for fetuses from gilts fed the control diet. Feeding L-carnitine may have decreased fetal IGF-II, therefore increasing cell proliferation and delaying cell differentiation. These results show that providing supplemental Lcarnitine to gestating gilts has beneficial effects on average fetal weight, possibly observed because of its ability to reduce fetal IGF-II concentrations

Effects of Crystalline Amino Acid Concentrations With or Without Formaldehyde Treatment of Diets on Nursery Pig Growth Performance and Fecal Bacterial Concentration

A total of 1,235 nursery pigs (PIC 359 × 1050; initially 26.9 lb BW) were used in a 28-d study evaluating the effects of crystalline amino acid concentrations with or without formaldehyde treatment of diets on nursery pig growth performance, feed bacteria concentration, lysine content, and fecal microbial diversity. Sal CURB (Kemin Industries Inc., Des Moines, IA) is a commercial formaldehyde product that is commonly utilized in the poultry industry for Salmonella control in feed but has also been shown to reduce PEDV infectivity in swine diets.Pigs were weaned at approximately 21 d, fed a common starter diet for 10 d, and allotted to pens based on BW in a completely randomized design. Experimental diets were fed in 2 phases (phase 1, d 0 to 12; and phase 2, 12 to 28 post-weaning) in meal form. Experimental treatments were arranged as a 2 × 2 + 1 factorial with main effects of formaldehyde (none vs. 0.30% in all phases) and crystalline AA concentration (low vs. high) plus a positive control. The positive control represented this current production system’s formulated Lys requirement needed to maximize performance, whereas treatment diets were formulated at 80% of the positive control’s lysine concentration. Feed bacterial concentration was determined by performing aerobic plate, Enterobacteriaceae, and total coliform counts on composited feed samples collected from each batch of feed manufactured at the feed mill and directly from feeders at the farm. Total, available, and free Lys analyses were conducted on composited feed samples collected from each phase of the study to determine Lys content. A composite fecal sample was collected from 3 randomly selected pigs per pen on d 28 for each treatment, DNA isolated, and each sample assessed for bacterial community analysis.Overall, a significant crystalline AA × formaldehyde interaction (P \u3c 0.05) was observed for ADFI and F/G. The interaction for ADFI was because added formaldehyde in high crystalline AA diets decreased feed intake; however, in low crystalline AA diets, ADFI was unchanged. For F/G, pigs had improved F/G in low crystalline AA diets without formaldehyde, but no difference was observed in high crystalline AA diets. Despite the interaction for ADFI and F/G, formaldehyde-treated diets reduced (P \u3c 0.05) ADG, ADFI, and resulted in poorer F/G. Crystalline AA concentration did not impact performance. Added formaldehyde reduced or eliminated bacterial concentration of complete feed in phase 1 of the study. Formaldehyde reduced total and available Lys in both low and high crystalline AA diets, with a greater reduction occurring in low crystalline AA diets, but had no effect on free Lys. Added formaldehyde reduced (P = 0.001) Lactobacillaceae bacterial species, but increased (P = 0.001) Clostridiaceae bacterial species in fecal microbial samples. As expected, formaldehyde treatment reduced bacterial microflora of complete feeds. Overall, the level of crystalline AA did not impact performance while the nursery diet formaldehyde addition negatively influenced growth performance, AA utilization, and fecal microbial diversity

Synaptogyrin-2 influences replication of Porcine circovirus 2

Porcine circovirus 2 (PCV2) is a circular single-stranded DNA virus responsible for a group of diseases collectively known as PCV2 Associated Diseases (PCVAD). Variation in the incidence and severity of PCVAD exists between pigs suggesting a host genetic component involved in pathogenesis. A large-scale genome-wide association study of experimentally infected pigs (n = 974), provided evidence of a host genetic role in PCV2 viremia, immune response and growth during challenge. Host genotype explained 64% of the phenotypic variation for overall viral load, with two major Quantitative Trait Loci (QTL) identified on chromosome 7 (SSC7) near the swine leukocyte antigen complex class II locus and on the proximal end of chromosome 12 (SSC12). The SNP having the strongest association, ALGA0110477 (SSC12), explained 9.3% of the genetic and 6.2% of the phenotypic variance for viral load. Dissection of the SSC12 QTL based on gene annotation, genomic and RNA-sequencing, suggested that a missense mutation in the SYNGR2 (SYNGR2 p.Arg63Cys) gene is potentially responsible for the variation in viremia. This polymorphism, located within a protein domain conserved across mammals, results in an amino acid variant SYNGR2 p.63Cys only observed in swine. PCV2 titer in PK15 cells decreased when the expression of SYNGR2 was silenced by specific-siRNA, indicating a role of SYNGR2 in viral replication. Additionally, a PK15 edited clone generated by CRISPR-Cas9, carrying a partial deletion of the second exon that harbors a key domain and the SYNGR2 p.Arg63Cys, was associated with a lower viral titer compared to wildtype PK15 cells (\u3e24 hpi) and supernatant (\u3e48hpi)(P \u3c 0.05). Identification of a non-conservative substitution in this key domain of SYNGR2 suggests that the SYNGR2 p.Arg63Cys variant may underlie the observed genetic effect on viral load

Synaptogyrin-2 influences replication of Porcine circovirus 2

Porcine circovirus 2 (PCV2) is a circular single-stranded DNA virus responsible for a group of diseases collectively known as PCV2 Associated Diseases (PCVAD). Variation in the incidence and severity of PCVAD exists between pigs suggesting a host genetic component involved in pathogenesis. A large-scale genome-wide association study of experimentally infected pigs (n = 974), provided evidence of a host genetic role in PCV2 viremia, immune response and growth during challenge. Host genotype explained 64% of the phenotypic variation for overall viral load, with two major Quantitative Trait Loci (QTL) identified on chromosome 7 (SSC7) near the swine leukocyte antigen complex class II locus and on the proximal end of chromosome 12 (SSC12). The SNP having the strongest association, ALGA0110477 (SSC12), explained 9.3% of the genetic and 6.2% of the phenotypic variance for viral load. Dissection of the SSC12 QTL based on gene annotation, genomic and RNA-sequencing, suggested that a missense mutation in the SYNGR2 (SYNGR2 p.Arg63Cys) gene is potentially responsible for the variation in viremia. This polymorphism, located within a protein domain conserved across mammals, results in an amino acid variant SYNGR2 p.63Cys only observed in swine. PCV2 titer in PK15 cells decreased when the expression of SYNGR2 was silenced by specific-siRNA, indicating a role of SYNGR2 in viral replication. Additionally, a PK15 edited clone generated by CRISPR-Cas9, carrying a partial deletion of the second exon that harbors a key domain and the SYNGR2 p.Arg63Cys, was associated with a lower viral titer compared to wildtype PK15 cells (\u3e24 hpi) and supernatant (\u3e48hpi)(P \u3c 0.05). Identification of a non-conservative substitution in this key domain of SYNGR2 suggests that the SYNGR2 p.Arg63Cys variant may underlie the observed genetic effect on viral load

β -decay half-lives of Sb 134,134m and their isomeric yield ratio produced by the spontaneous fission of Cf 252

A number of fission products possess isomeric states which have a nuclear spin significantly different from that of the ground state. The yield ratio of these states following fission is influenced by the angular momentum present in the fissioning system. The Sb134m,134 yield ratio had not been previously measured in the spontaneous fission of Cf252; however, it had previously been observed to favor the (7-) isomer over the (0-) ground state in U235(nth,f) and Th232(25 MeV p,f). Using a mass-separated beam of low-energy Sb134,134m ions produced by Cf252 spontaneous fission at the CARIBU facility, β particles and γ rays were detected using the SATURN/X-Array decay station to determine the fission-yield ratio and β-decay half-lives. The Sb134m to Sb134 fission yield was determined to be 2.03±0.05 and the half-lives of Sb134m and Sb134 were found to be 9.87±0.08 s and 0.674±0.004 s, respectively. These results represent the first isomeric yield ratio measurement for this nucleus, and improved measurements of the Sb134 ground state and the Sb134m isomer half-lives

Limit on Tensor Currents from Li 8 β Decay

In the standard model, the weak interaction is formulated with a purely vector-axial-vector (V-A) structure. Without restriction on the chirality of the neutrino, the most general limits on tensor currents from nuclear β decay are dominated by a single measurement of the β-ν¯ correlation in He6 β decay dating back over a half century. In the present work, the β-ν¯-α correlation in the β decay of Li8 and subsequent α-particle breakup of the Be8∗ daughter was measured. The results are consistent with a purely V-A interaction and in the case of couplings to right-handed neutrinos (CT=-CT′) limits the tensor fraction to |CT/CA|2\u3c0.011 (95.5% C.L.). The measurement confirms the He6 result using a different nuclear system and employing modern ion-trapping techniques subject to different systematic uncertainties

Recoil ions from the β decay of Sb 134 confined in a Paul trap

The low-energy recoiling ions from the β decay of Sb134 were studied by using the Beta-decay Paul Trap. Using this apparatus, singly charged ions were suspended in vacuum at the center of a detector array used to detect emitted β particles, γ rays, and recoil ions in coincidence. The recoil ions emerge from the trap with negligible scattering, allowing β-decay properties and the charge-state distribution of the daughter ions to be determined from the β-ion coincidences. First-forbidden β-decay theory predicts a β-ν correlation coefficient of nearly unity for the 0- to 0+ transition from the ground state of Sb134 to the ground state of Te134. Although this transition was expected to have a nearly 100% branching ratio, an additional 17.2(52)% of the β-decay strength must populate high-lying excited states to obtain an angular correlation consistent with unity. The extracted charge-state distribution of the recoiling ions was compared with existing β-decay results and the average charge state was found to be consistent with the results from lighter nuclei