151 research outputs found

    Local Drivers of Marine Heatwaves: A Global Analysis With an Earth System Model

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    Marine heatwaves (MHWs) are periods of extreme warm ocean temperatures that can have devastating impacts on marine organisms and socio-economic systems. Despite recent advances in understanding the underlying processes of individual events, a global view of the local oceanic and atmospheric drivers of MHWs is currently missing. Here, we use daily-mean output of temperature tendency terms from a comprehensive fully coupled coarse-resolution Earth system model to quantify the main local processes leading to the onset and decline of surface MHWs in different seasons. The onset of MHWs in the subtropics and mid-to-high latitudes is primarily driven by net ocean heat uptake associated with a reduction of latent heat loss in all seasons, increased shortwave heat absorption in summer and reduced sensible heat loss in winter, dampened by reduced vertical mixing from the non-local portion of the K-Profile Parameterization boundary layer scheme (KPP) especially in summer. In the tropics, ocean heat uptake is reduced and lowered vertical local mixing and diffusion cause the warming. In the subsequent decline phase, increased ocean heat loss to the atmosphere due to enhanced latent heat loss in all seasons together with enhanced vertical local mixing and diffusion in the high latitudes during summer dominate the temperature decrease globally. The processes leading to the onset and decline of MHWs are similar for short and long MHWs, but there are differences in the drivers between summer and winter. Different types of MHWs with distinct driver combinations are identified within the large variability among events. Our analysis contributes to a better understanding of MHW drivers and processes and may therefore help to improve the prediction of high-impact marine heatwaves

    Metal artifact reduction in 68^{68}Ga-PSMA-11 PET/MRI for prostate cancer patients with hip joint replacement using multiacquisition variable-resonance image combination

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    BACKGROUND PET/MRI has a high potential in oncology imaging, especially for tumor indications where high soft tissue contrast is crucial such as genitourinary tumors. One of the challenges for PET/MRI acquisition is handling of metal implants. In addition to conventional methods, more innovative techniques have been developed to reduce artifacts caused by those implants such as the selective multiacquisition variable-image combination (MAVRIC-SL). The aim of this study is to perform a quantitative and qualitative assessment of metal artifact reduction in 68^{68}Ga-PSMA-11 PET/MRI for prostate cancer patients with hip joint replacement using a selective MAVRIC-SL sequence for the whole pelvis. METHODS We retrospectively analyzed data of 20 men with 37 metal hip implants diagnosed with PCA, staged or restaged by 68^{68}Ga-PSMA-11 PET/MRI from June 2016 to December 2017. Each signal cancellation per side or metal implant was analyzed on the reference sequence LAVA-FLEX, as well as T1-weighted fast spin echo (T1w-FSE) sequence and MAVRIC-SL. Two independent reviewers reported on a four-point scale whether abnormal pelvic 68^{68}Ga-PSMA-11 uptake could be assigned to an anatomical structure in the tested sequences. RESULTS The smallest averaged signal void was observed on MAVRIC-SL sequences with a mean artifact size of 26.17 cm2^{2} (range 12.63 to 42.93 cm2^{2}, p < 0.001). The best image quality regarding anatomical assignment of pathological PSMA uptakes in the pelvis by two independent readers was noted for MAVRIC-SL sequences, followed by T1w-FSE with excellent interreader agreement. CONCLUSIONS MAVRIC-SL sequence allows better image quality in the surrounding of hip implants by reducing MR signal voids and increasing so the accuracy of anatomical assignment of pathological 68^{68}Ga-PSMA-11 uptake in the pelvis over LAVA-FLEX and T1w-FSE sequences

    Irreversible loss in marine ecosystem habitability after a temperature overshoot

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    Anthropogenic warming of the oceans and associated deoxygenation are altering marine ecosystems. Current knowledge suggests these changes may be reversible on a centennial timescale at the ocean surface but irreversible at deeper depths even if global warming were to ameliorate. In contrast, the marine ecosystem’s response to these persistent changes remains poorly elucidated. Here we explore to what extent global warming may drive alterations in marine habitats by exploring the evolution of a metabolic index that captures marine organisms’ ecophysiological response to both temperature and oxygen changes, throughout an idealised ramp-up/ramp-down atmospheric carbon dioxide concentration and an overshoot scenarios. Using a multi-model approach; we find that changes in ocean temperature and oxygen drive a centuries-long irreversible loss in the habitable volume of the upper 1000 m of the world ocean. These results suggest that the combined effect of warming and deoxygenation will have profound and long-lasting impacts on the viability of marine ecosystems, well after global temperatures have peaked.publishedVersio

    KiDS-1000 Cosmology: Constraints from density split statistics

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    Context. Weak lensing and clustering statistics beyond two-point functions can capture non-Gaussian information about the matter density field, thereby improving the constraints on cosmological parameters relative to the mainstream methods based on correlation functions and power spectra. Aims. This paper presents a cosmological analysis of the fourth data release of the Kilo Degree Survey based on the density split statistics, which measures the mean shear profiles around regions classified according to foreground densities. The latter is constructed from a bright galaxy sample, which we further split into red and blue samples, allowing us to probe their respective connection to the underlying dark matter density. Methods. We use the state-of-the-art model of the density splitting statistics and validate its robustness against mock data infused with known systematic effects such as intrinsic galaxy alignment and baryonic feedback. Results. After marginalising over the photometric redshift uncertainty and the residual shear calibration bias, we measure for the full KiDS-bright sample a structure growth parameter of S8=σ8Ωm/0.3=0.740.02+0.03S_8 = \sigma_8 \sqrt{\Omega_\mathrm{m}/0.3} = 0.74^{+0.03}_{-0.02} that is competitive to and consistent with two-point cosmic shear results, a matter density of Ωm=0.28±0.02\Omega_\mathrm{m} = 0.28 \pm 0.02, and a constant galaxy bias of b=1.320.10+0.12b = 1.32^{+0.12}_{-0.10}.Comment: 18 pages, 23 Figures. Submitted to A&

    Is there warming in the pipeline? A multi-model analysis of the Zero Emissions Commitment from CO<sub>2</sub>

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    The Zero Emissions Commitment (ZEC) is the change in global mean temperature expected to occur following the cessation of net CO2 emissions and as such is a critical parameter for calculating the remaining carbon budget. The Zero Emissions Commitment Model Intercomparison Project (ZECMIP) was established to gain a better understanding of the potential magnitude and sign of ZEC, in addition to the processes that underlie this metric. A total of 18 Earth system models of both full and intermediate complexity participated in ZECMIP. All models conducted an experiment where atmospheric CO2 concentration increases exponentially until 1000 PgC has been emitted. Thereafter emissions are set to zero and models are configured to allow free evolution of atmospheric CO2 concentration. Many models conducted additional second-priority simulations with different cumulative emission totals and an alternative idealized emissions pathway with a gradual transition to zero emissions. The inter-model range of ZEC 50 years after emissions cease for the 1000 PgC experiment is −0.36 to 0.29 ∘C, with a model ensemble mean of −0.07 ∘C, median of −0.05 ∘C, and standard deviation of 0.19 ∘C. Models exhibit a wide variety of behaviours after emissions cease, with some models continuing to warm for decades to millennia and others cooling substantially. Analysis shows that both the carbon uptake by the ocean and the terrestrial biosphere are important for counteracting the warming effect from the reduction in ocean heat uptake in the decades after emissions cease. This warming effect is difficult to constrain due to high uncertainty in the efficacy of ocean heat uptake. Overall, the most likely value of ZEC on multi-decadal timescales is close to zero, consistent with previous model experiments and simple theory

    Spaces of Yoga – Towards a Non-Essentialist Understanding of Yoga

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    This chapter will examine some of the spaces that yoga occupies in the contemporary world, both physical and social. By looking at yoga through the focus of particular, contested spaces and locations, it will be argued that overarching essentialist definitions of yoga are impossible, although individuals and social groups can and do create essentialist definitions that are more or less useful for particular purposes. By exploring these narratives and boundaries in the context of specific locations, we can better understand what people are doing with the collection of beliefs and practices known as yoga

    Lung Volume, Breathing Pattern and Ventilation Inhomogeneity in Preterm and Term Infants

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    BACKGROUND: Morphological changes in preterm infants with bronchopulmonary dysplasia (BPD) have functional consequences on lung volume, ventilation inhomogeneity and respiratory mechanics. Although some studies have shown lower lung volumes and increased ventilation inhomogeneity in BPD infants, conflicting results exist possibly due to differences in sedation and measurement techniques. METHODOLOGY/PRINCIPAL FINDINGS: We studied 127 infants with BPD, 58 preterm infants without BPD and 239 healthy term-born infants, at a matched post-conceptional age of 44 weeks during quiet natural sleep according to ATS/ERS standards. Lung function parameters measured were functional residual capacity (FRC) and ventilation inhomogeneity by multiple breath washout as well as tidal breathing parameters. Preterm infants with BPD had only marginally lower FRC (21.4 mL/kg) than preterm infants without BPD (23.4 mL/kg) and term-born infants (22.6 mL/kg), though there was no trend with disease severity. They also showed higher respiratory rates and lower ratios of time to peak expiratory flow and expiratory time (t(PTEF)/t(E)) than healthy preterm and term controls. These changes were related to disease severity. No differences were found for ventilation inhomogeneity. CONCLUSIONS: Our results suggest that preterm infants with BPD have a high capacity to maintain functional lung volume during natural sleep. The alterations in breathing pattern with disease severity may reflect presence of adaptive mechanisms to cope with the disease process
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