190 research outputs found
A study of bubble entrainment as related to runner velocity in aluminum sand castings using the Cosworth process.
Alcohol from municipal refuse by the hydrolysis fermentation process as a solid waste solution for Cascade County, Montana
The emergence and development of maintained secondary education in ealing1902-1944
The thesis attempts to explain the emergence of maintained secondary education in Ealing by 1913 and to describe the subsequent development of the maintained secondary schools up to 1944. These developments are set within the context of the community which formed the borough and of the county of Middlesex. They are related to contemporary educational ideas and practices. Contributory demographic, social and political influences on the development of maintained secondary education in Ealing are identified and an assessment of the roles of influential personalities is undertaken. Some appraisal of the success or otherwise of Middlesex and Ealing policy and of the place of this policy within the national framework is offered. An effort has been made to portray adequately the educational experiences of boys and girls at the Ealing County Secondary Schools in the period 1913-1944.The possibility of a thesis first arose with the acquisition of notebooks and documents belonging to the late Mr. E.P.H. Pugh. These were kindly lent by Mrs. Pugh. The notebooks contain copies of documents relating to many aspects of Ealing's history including some relevant to education. The documents in the collection include some annual reports of the Ealing Educational Association and the Ealing Education Committee together with letters and papers concerned with discussions prior to the implementation of the 1944 Education Act in the borough. As such the collection has been a useful springboard from which to launch a study of secondary education in Ealing between 1902 and 1944.other local primary sources consulted are to be found in the Ealing Reference Library and the Greater London Records Office and History Library. They include newspapers, the minutes of various education, borough and county committees, head teachersâ reports, the reports of H,M. school inspectors and the texts of various addresses and lectures given during the period by the personalities involved. National primary sources consulted are to be found in the Public Records Office. Attempts were made to contact former pupils and teachers who worked in the Ealing County Schools between 1913 and 194.4,. Those who contributed are listed in the bibliography
Prospective survey of veterinary practitionersâ primary assessment of equine colic: clinical features, diagnoses, and treatment of 120 cases of large colon impaction
Background
Large colon impactions are a common cause of colic in the horse. There are no scientific reports on the clinical presentation, diagnostic tests and treatments used in first opinion practice for large colon impaction cases. The aim of this study was to describe the presentation, diagnostic approach and treatment at the primary assessment of horses with large colon impactions.
Methods
Data were collected prospectively from veterinary practitioners on the primary assessment of equine colic cases over a 12 month period. Inclusion criteria were a diagnosis of primary large colon impaction and positive findings on rectal examination. Data recorded for each case included history, signalment, clinical and diagnostic findings, treatment on primary assessment and final case outcome. Case outcomes were categorised into three groups: simple medical (resolved with single treatment), complicated medical (resolved with multiple medical treatments) and critical (required surgery, were euthanased or died). Univariable analysis using one-way ANOVA and Tukeyâs post-hoc test, Kruskal Wallis with Dunnâs post-hoc test and Chi squared analysis were used to compare between different outcome categories.
Results
1032 colic cases were submitted by veterinary practitioners: 120 cases met the inclusion criteria for large colon impaction. Fifty three percent of cases were categorised as simple medical, 36.6% as complicated medical, and 9.2% as critical. Most cases (42.1%) occurred during the winter. Fifty nine percent of horses had had a recent change in management, 43% of horses were not ridden, and 12.5% had a recent / current musculoskeletal injury. Mean heart rate was 43bpm (range 26-88) and most cases showed mild signs of pain (67.5%) and reduced gut sounds (76%). Heart rate was significantly increased and gut sounds significantly decreased in critical compared to simple medical cases (p<0.05). Fifty different treatment combinations were used, with NSAIDs (93%) and oral fluids (71%) being administered most often.
Conclusions
Large colon impactions typically presented with mild signs of colic; heart rate and gut sounds were the most useful parameters to distinguish between simple and critical cases at the primary assessment. The findings of seasonal incidence and associated management factors are consistent with other studies. Veterinary practitioners currently use a wide range of different treatment combinations for large colon impactions
A Model for Sustaining Participation with Hard-to-Serve Clients: The Learning Continuum
This article reports on a model developed by the Florida Crown Workforce Board in cooperation with the University of Florida\u27 s Welfare to Work Initiative. The model proposes a sustained educational experience that includes a variety of activities to enable welfare transition clients to become employed and self-sufficient. The concept of a Learning Continuum is described, and implications for Extension are discussed
Risk factors for acute abdominal pain (colic) in the adult horse: A scoping review of risk factors, and a systematic review of the effect of management-related changes
Acute abdominal pain (colic) is the most common reason for emergency veterinary treatment in the horse. Consolidation of data through a systematic review is important to inform evidence-based medicine and clinical guidelines, but there are currently no published systematic reviews on colic in the horse. The aim of this study was to identify, categorize and appraise the evidence on factors associated with increased risk of developing abdominal pain (colic) due to gastrointestinal disease in the adult horse. A scoping review was performed to identify and categorize evidence on all risk factors for colic. A systematic review of management-related risk factors was then performed following PRISMA guidelines. Both searches were conducted in Medline, CAB Abstracts and Web of Science databases, and publications were assessed against inclusion and exclusion criteria. For the scoping review, study and participant characteristics of included publications and key results were extracted and tabulated. For the systematic review, cohort, case-control or cross-sectional studies investigating acute abdominal pain in horses within two weeks of management changes were assessed. Study characteristics, participant characteristics and study results of included publications for the systematic review were extracted and tabulated. Included publications were appraised using the Joanna Briggs Institute Critical Appraisal Tools for cohort, case-control and cross-sectional studies. The scoping review search identified 3,756 publications. Fifty eight studies met final inclusion criteria, and 22 categories of risk factors were identified. These were grouped into three broad areas: horse-related factors, management-related factors and environment-related factors. The largest body of evidence related to management change. The systematic review of management change identified 410 publications: 14 met inclusion criteria for analysis. These consisted of one cohort, eight case-control and five cross-sectional studies. The studies were conducted between 1990â2008, and the majority of studies were located in the USA (8/14) or UK (3/14). The risk factors related to management change that were assessed were feed, carer, exercise, pasture, water and housing. The largest bodies of evidence for increased risk of colic associated with management change were changes in feed (5/14 publications) and recent change in housing (3/14). Most studies (8/14) did not meet the JBI criterion on confounding factors. There was marked heterogeneity of study methodologies and measures. This is the first study to use a combined scoping and systematic review to analyse evidence for modifiable risk factors for a common condition in the horse. It provides a comprehensive review that will be a key resource for researchers, veterinary practitioners and horse owners. It identified modifiable risk factors associated with an increased risk of colic which should be a key target for preventative health programmes. The findings from the critical appraisal were used to develop recommendations for future research to improve the quality of evidence-based veterinary medicine
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Highly accurate detection of ovarian cancer using CA125 but limited improvement with serum matrix-assisted laser desorption/ionization time-of-flight mass spectrometry profiling
Objectives: Our objective was to test the performance of CA125 in classifying serum samples from a cohort of malignant and benign ovarian cancers and age-matched healthy controls and to assess whether combining information from matrix-assisted laser desorption/ionization (MALDI) time-of-flight profiling could improve diagnostic performance.
Materials and Methods: Serum samples from women with ovarian neoplasms and healthy volunteers were subjected to CA125 assay and MALDI time-of-flight mass spectrometry (MS) profiling. Models were built from training data sets using discriminatory MALDI MS peaks in combination with CA125 values and tested their ability to classify blinded test samples. These were compared with models using CA125 threshold levels from 193 patients with ovarian cancer, 290 with benign neoplasm, and 2236 postmenopausal healthy controls.
Results: Using a CA125 cutoff of 30 U/mL, an overall sensitivity of 94.8% (96.6% specificity) was obtained when comparing malignancies versus healthy postmenopausal controls, whereas a cutoff of 65 U/mL provided a sensitivity of 83.9% (99.6% specificity). High classification accuracies were obtained for early-stage cancers (93.5% sensitivity). Reasons for high accuracies include recruitment bias, restriction to postmenopausal women, and inclusion of only primary invasive epithelial ovarian cancer cases. The combination of MS profiling information with CA125 did not significantly improve the specificity/accuracy compared with classifications on the basis of CA125 alone.
Conclusions: We report unexpectedly good performance of serum CA125 using threshold classification in discriminating healthy controls and women with benign masses from those with invasive ovarian cancer. This highlights the dependence of diagnostic tests on the characteristics of the study population and the crucial need for authors to provide sufficient relevant details to allow comparison. Our study also shows that MS profiling information adds little to diagnostic accuracy. This finding is in contrast with other reports and shows the limitations of serum MS profiling for biomarker discovery and as a diagnostic too
Crossâsectional study of UK horse owner's purchase and euthanasia decisionâmaking for their horse
Background: This cross-sectional study aimed to investigate factors affecting horse ownersâ purchase and euthanasia decisions that had been identified in a qualitative study. Methods: An online survey on horse ownersâ purchase and euthanasia decisions and experiences was distributed using snowball sampling. Inclusion criteria were previous experience of purchase or euthanasia decisions. Descriptive data analyses (mean, median, mode and frequency percentages) were performed. Results: There were 451 participants from the UK and Ireland, 97% were female with a median age of 45 years. Participants most frequently did not seek any advice when deciding what type of horse to purchase (38.6%, 169/438) or if it was priced appropriately (48.7%, 214/439). Most participants were satisfied with their purchase and would purchase their horse again (84.9%, 370/436). The most frequent reasons for euthanasia were injury/illness with low chance of survival (55.2%, 201/364), poor quality of life (42.6%, 155/363) and long-term injury (35.7%, 130/364). Most participants sought advice or guidance when making end-of-life decisions (87.5%, 328/375), and 55% (243/440) had a euthanasia plan in place. Conclusions: Owners show limited advice-seeking behaviour on key aspects of purchase decisions. Owners frequently seek advice on euthanasia decisions, and the majority of decisions were based on welfare concerns
Developing consensus for definitions of key veterinaryâspecific quality improvement (QI) terms using an eDelphiâstudy method
Quality Improvement: origins, purpose and the future for veterinary practice
Providing the highest quality veterinary care can often be a delicate balancing act: the client/ownerâs wishes, financial parameters and emotional needs have to be considered, whilst also meeting the animalâs clinical needs. But what actually defines quality care? It is a term frequently used in both the human and veterinary healthcare literature, but often has little explanation or definition attached to it. âQualityâ in relation to care delivered is not a static concept and will hold different meanings to different individuals within a healthcare service. John Ruskin, a Victorian writer and critic of art and society observed: âQuality is never an accident; it is always the result of high intention, sincere effort, intelligent direction and skilful executionâ
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