941 research outputs found
Earthquake waves and the mechanical properties of the earth's interior
It has come to be realized in the present century that the science of Seismology, in addition to providing information on the nature and characteristics of earthquakes, is a central source of knowledge of the mechanics and layering of the Earth's deep interior.It has come to be realized in the present century that the science of Seismology, in addition to providing information on the nature and characteristics of earthquakes, is a central source of knowledge of the mechanics and layering of the Earth's deep interior
Earthquake networks based on similar activity patterns
Earthquakes are a complex spatiotemporal phenomenon, the underlying mechanism
for which is still not fully understood despite decades of research and
analysis. We propose and develop a network approach to earthquake events. In
this network, a node represents a spatial location while a link between two
nodes represents similar activity patterns in the two different locations. The
strength of a link is proportional to the strength of the cross-correlation in
activities of two nodes joined by the link. We apply our network approach to a
Japanese earthquake catalog spanning the 14-year period 1985-1998. We find
strong links representing large correlations between patterns in locations
separated by more than 1000 km, corroborating prior observations that
earthquake interactions have no characteristic length scale. We find network
characteristics not attributable to chance alone, including a large number of
network links, high node assortativity, and strong stability over time.Comment: 8 pages text, 9 figures. Updated from previous versio
Experimental Demonstration of Squeezed State Quantum Averaging
We propose and experimentally demonstrate a universal quantum averaging
process implementing the harmonic mean of quadrature variances. The harmonic
mean protocol can be used to efficiently stabilize a set of fragile squeezed
light sources with statistically fluctuating noise levels. The averaged
variances are prepared probabilistically by means of linear optical
interference and measurement induced conditioning. We verify that the
implemented harmonic mean outperforms the standard arithmetic mean strategy.
The effect of quantum averaging is experimentally tested both for uncorrelated
and partially correlated noise sources with sub-Poissonian shot noise or
super-Poissonian shot noise characteristics.Comment: 4 pages, 5 figure
Impact of controlled vacuum induced surface freezing on the freeze drying of human plasma
During the freezing step of a typical freeze drying process, the temperature at which nucleation is induced is generally stochastically distributed, resulting in undesired within-batch heterogeneity. Controlled nucleation techniques have been developed to address this problem; these make it possible to trigger the formation of ice crystals at the same time and temperature in all the batch. Here, the controlled nucleation technique known as vacuum induced surface freezing is compared to spontaneous freezing for the freeze drying of human plasma, a highly concentrated system commonly stored in a dried state. The potency of Factor VIII (FVIII), a sensitive, labile protein present in plasma, and the reconstitution time of the dried cakes are evaluated immediately after freeze drying, and after 1, 3, 6 or 9 months storage at different degradation temperatures. We show that the application of controlled nucleation significantly reduces the reconstitution time and in addition helps to improve FVIII stability
Switching the World's Salt Supply—Learning from Iodization to Achieve Potassium Enrichment
Sodium is an essential dietary component, but excess sodium intake can lead to high blood pressure and an increased risk of cardiovascular disease. Many national and international bodies, including the World Health Organization, have advocated for population-wide sodium reduction interventions. Most have been unsuccessful due to inadequate sodium reduction by food industry and difficulties in persuading consumers to add less salt to food. Recent research highlights potassium-enriched salt as a new, feasible, acceptable, and scalable approach to reducing the harms caused by excess sodium and inadequate potassium consumption. Modeling shows that a global switch from regular salt to potassium-enriched salt has the potential to avert millions of strokes, heart attacks, and premature deaths worldwide each year. There will be many challenges in switching the world's salt supply to potassium-enriched salt, but the success of universal salt iodization shows that making a global change to the manufacture and use of salt is a tractable proposition. This in-depth review of universal salt iodization identified the importance of a multisectoral effort with strong global leadership, the support of multilateral organizations, engagement with the salt industry, empowered incountry teams, strong participation of national governments, understanding the salt supply chain, and a strategic advocacy and communication plan. Key challenges to the implementation of the iodization program were costs to government, industry, and consumers, industry concerns about consumer acceptability, variance in the size and capabilities of salt producers, inconsistent quality control, ineffective regulation, and trade-related regulatory issues. Many of the opportunities and challenges to universal salt iodization will likely also be applicable to switching the global salt supply to iodized and potassium-enriched salt
Geophysical studies with laser-beam detectors of gravitational waves
The existing high technology laser-beam detectors of gravitational waves may
find very useful applications in an unexpected area - geophysics. To make
possible the detection of weak gravitational waves in the region of high
frequencies of astrophysical interest, ~ 30 - 10^3 Hz, control systems of laser
interferometers must permanently monitor, record and compensate much larger
external interventions that take place in the region of low frequencies of
geophysical interest, ~ 10^{-5} - 3 X 10^{-3} Hz. Such phenomena as tidal
perturbations of land and gravity, normal mode oscillations of Earth,
oscillations of the inner core of Earth, etc. will inevitably affect the
performance of the interferometers and, therefore, the information about them
will be stored in the data of control systems. We specifically identify the
low-frequency information contained in distances between the interferometer
mirrors (deformation of Earth) and angles between the mirrors' suspensions
(deviations of local gravity vectors and plumb lines). We show that the access
to the angular information may require some modest amendments to the optical
scheme of the interferometers, and we suggest the ways of doing that. The
detailed evaluation of environmental and instrumental noises indicates that
they will not prevent, even if only marginally, the detection of interesting
geophysical phenomena. Gravitational-wave instruments seem to be capable of
reaching, as a by-product of their continuous operation, very ambitious
geophysical goals, such as observation of the Earth's inner core oscillations.Comment: 29 pages including 8 figures, modifications and clarifications in
response to referees' comments, to be published in Class. Quant. Gra
Biogenesis of the inner membrane complex is dependent on vesicular transport by the alveolate specific GTPase Rab11B
Apicomplexan parasites belong to a recently recognised group of protozoa referred to as Alveolata. These protists contain membranous sacs (alveoli) beneath the plasma membrane, termed the Inner Membrane Complex (IMC) in the case of Apicomplexa. During parasite replication the IMC is formed de novo within the mother cell in a process described as internal budding. We hypothesized that an alveolate specific factor is involved in the specific transport of vesicles from the Golgi to the IMC and identified the small GTPase Rab11B as an alveolate specific Rab-GTPase that localises to the growing end of the IMC during replication of Toxoplasma gondii. Conditional interference with Rab11B function leads to a profound defect in IMC biogenesis, indicating that Rab11B is required for the transport of Golgi derived vesicles to the nascent IMC of the daughter cell. Curiously, a block in IMC biogenesis did not affect formation of sub-pellicular microtubules, indicating that IMC biogenesis and formation of sub-pellicular microtubules is not mechanistically linked. We propose a model where Rab11B specifically transports vesicles derived from the Golgi to the immature IMC of the growing daughter parasites
Reaction Between Nitrogen and Spinel in Chromium
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/66029/1/j.1151-2916.1968.tb15671.x.pd
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