Sistema de autoevaluación y evaluación continuada del grado de aprendizaje del alumnado, mediante metodologias de portafolio electrónico del/la estudiante.

Diseño e implantación de un Campus Virtual y de un portafolio electrónico de auto-evaluación continuada del aprendizaje del/la alumno/a, mediante la plataforma informática Moodle, para la asignatura de Proyectos de la titulación de Enginyeria en Organització Industrial. En este Campus Virtual el/la alumno/a tendrá a su disposición toda la información necesaria para el seguimiento de la asignatura, podrá acceder directamente al actual entorno virtual donde se realizan los trabajos de grupo, en un portafolio electrónico de grupo, y tendrá una zona de auto-evaluación a través de test creados por los profesores/as y a los que el/la alumno/a sólo podrá acceder en determinados momentos del horario de clase. Por medio de los resultados proporcionados tras la realización de cada test, tanto el/la alumno/a como el profesor/a, podrán saber el nivel de los conocimientos aprendidos individualmente con el estudio de cada tema y la realización en grupo del ejercicio correspondiente. Esta batería de test servirá para ayudar al/la alumno/a a consolidar los conocimientos adquiridos, prepararse para la realización del siguiente ejercicio, prepararse para el examen final y para subir la nota final de la asignatura

Plan de intervención de fisioterapia para el síndrome del túnel carpiano moderado: A propósito de un caso

Introducción: El síndrome del túnel carpiano (STC) es la neuropatía periférica por atrapamiento más frecuente. En su comienzo predominan los síntomas sensitivos y a medida que progresa se suman síntomas motores, pudiendo llegar a ser una patología muy incapacitante. Se indica tratamiento conservador en cuadros leves y moderados y cirugía descompresiva en cuadros severos o tras fracaso del conservador. Objetivos: Diseñar y evaluar un plan de intervención de fisioterapia para el STC de intensidad media, teniendo en cuenta la evidencia más actual.Metodología: Se realizó un estudio experimental de tipo caso clínico (n=1) en el que se llevó a cabo un tratamiento fisioterápico con tres evaluaciones. Las variables dependientes evaluadas fueron: mecanosensibilidad del nervio, sensibilidad superficial, rango articular, tono muscular, fuerza de prensión, capacidad funcional y calidad de vida. La variable independiente fue el tratamiento, el cual incluyó educación para la paciente, ejercicios de movilidad y fortalecimiento, estiramientos, apertura y cierre del canal carpiano, masoterapia, fibrólisis diacutánea, técnicas neurodinámicas y kinesiotaping. Resultados: Se evidenció una significativa disminución del dolor (EVA de 0 y 1) y mejoría del resto de variables dependientes.Conclusiones: La intervención fisioterápica realizada resultó eficaz a corto plazo, atendiendo al cumplimiento de los objetivos terapéuticos planteados y a la mejora de las variables estudiadas. <br /

Sistema de autoevaluación y evaluación continuada del grado de aprendizaje del alumnado, mediante metodologias de portafolio electrónico del/la estudiante.

Diseño e implantación de un Campus Virtual y de un portafolio electrónico de auto-evaluación continuada del aprendizaje del/la alumno/a, mediante la plataforma informática Moodle, para la asignatura de Proyectos de la titulación de Enginyeria en Organització Industrial. En este Campus Virtual el/la alumno/a tendrá a su disposición toda la información necesaria para el seguimiento de la asignatura, podrá acceder directamente al actual entorno virtual donde se realizan los trabajos de grupo, en un portafolio electrónico de grupo, y tendrá una zona de auto-evaluación a través de test creados por los profesores/as y a los que el/la alumno/a sólo podrá acceder en determinados momentos del horario de clase. Por medio de los resultados proporcionados tras la realización de cada test, tanto el/la alumno/a como el profesor/a, podrán saber el nivel de los conocimientos aprendidos individualmente con el estudio de cada tema y la realización en grupo del ejercicio correspondiente. Esta batería de test servirá para ayudar al/la alumno/a a consolidar los conocimientos adquiridos, prepararse para la realización del siguiente ejercicio, prepararse para el examen final y para subir la nota final de la asignatura

Epitope mapping of the major allergen 2S albumin from pine nut

5 Pág. Departamento de Tecnología de Alimentos​​The epitopes of the major allergen of pine nut, Pin p 1, were analyzed using a peptide library and sera from patients with clinical allergy to pine nut in order to deepen into the allergenic characteristics of Pin p 1. Analyses of epitope similarities and epitopes location in a 3D-model were also performed. Results showed that three main regions of Pin p 1 containing 5 epitopes were recognized by patient sera IgE. The epitopes of Pin p 1 had important similarities with epitopes of allergenic 2S albumins from peanut (Ara h 2 and 6) and Brazil nut (Ber e 1). The epitopes of Pin p 1 were found in α-helices and coils in the 3D protein structure. Interestingly, all epitopes were found to be well-exposed in the protein surface, which suggests facile access for IgE-binding to the structure of Pin p 1 which is known to be highly resistant.This work was supported by a grant from the research program Talento Investigador of the Community of Madrid (Regional Ministry of Science, Universities, and Innovation, Madrid, Spain), and a grant from Strategic Health Action (AES 2020), Carlos III Health Institute, Spanish Ministry of Science and Innovation (to B.C) (Grant number: PI20/00351). B.C. is senior researcher in the research program Talento Investigador of the Community of Madrid (number: 2019-T1/BIO-12690). The funding sources had no role in the study design; in the collection, analysis and interpretation of data; in the writing of the manuscript; and in the decision to submit the article for publication.Peer reviewe

Characterization of Relevant Biomarkers for the Diagnosis of Food Allergies: An Overview of the 2S Albumin Family

2S albumins are relevant and often major allergens from several tree nuts and seeds, affecting mainly children and young people. The present study aims to assess how the structural features of 2S albumins could affect their immunogenic capacity, which is essential to comprehend the role of these proteins in food allergy. For this purpose, twelve 2S albumins were isolated from their respective extracts by chromatographic methods and identified by MALDI-TOF mass-spectrometry. Their molecular and structural characterization was conducted by electrophoretic, spectroscopic and in silico methods, showing that these are small proteins that comprise a wide range of isoelectric points, displaying a general high structure stability to thermal treatment. Despite low amino acid sequence identity, these proteins share structural features, pointing conformational epitopes to explain cross-reactivity between them. Immunoblotting with allergic patients' sera revealed those possible correlations between evolutionarily distant 2S albumins from different sources. The availability of a well-characterized panel of 2S albumins from plant-derived sources allowed establishing correlations between their structural features and their allergenic potential, including their role in cross-reactivity processes

Characterization of Relevant Biomarkers for the Diagnosis of Food Allergies: An Overview of the 2S Albumin Family

2S albumins are relevant and often major allergens from several tree nuts and seeds, affecting mainly children and young people. The present study aims to assess how the structural features of 2S albumins could affect their immunogenic capacity, which is essential to comprehend the role of these proteins in food allergy. For this purpose, twelve 2S albumins were isolated from their respective extracts by chromatographic methods and identified by MALDI-TOF massspectrometry. Their molecular and structural characterization was conducted by electrophoretic, spectroscopic and in silico methods, showing that these are small proteins that comprise a wide range of isoelectric points, displaying a general high structure stability to thermal treatment. Despite low amino acid sequence identity, these proteins share structural features, pointing conformational epitopes to explain cross-reactivity between them. Immunoblotting with allergic patients’ sera revealed those possible correlations between evolutionarily distant 2S albumins from different sources. The availability of a well-characterized panel of 2S albumins from plant-derived sources allowed establishing correlations between their structural features and their allergenic potential, including their role in cross-reactivity processesMinisterio de Economia y ́CompetitividadFEDER fundsMinisterio de EducaciónDepto. de Bioquímica y Biología MolecularFac. de Ciencias QuímicasTRUEpu

Effect of Milking Maneuver in Preterm Infants: A Randomized Controlled Trial

OBJECTIVE: To assess the short and medium-term effects of milking maneuver (MM) compared with early cord clamping for infants born before 37 weeks of pregnancy. MATERIAL AND METHODS: 138 infants between 24+0 and 36+6 weeks of gestation were allocated to MM or early cord clamping. Primary outcomes were the requirement of red blood cell transfusions or phototherapy. RESULTS: Initial hemoglobin was significantly higher in the MM group by 1.675 g/dL (p < 0.05) and initial hematocrit by 5.36% (p < 0.05), but no differences in the need of transfusion during the first 30 days after delivery were found (RR 0.8; 95% CI 0.22-2.85). Peak serum bilirubin was similar in both groups (11,097 ± 3.21 vs. 11,247 ± 3.56 mg/dL, p = 0.837). Phototherapy requirements were higher in the MM group (RR 1.62; 95% CI 1.1-2.38). No differences regarding the need of oral iron supplementation, platelet transfusion, respiratory distress syndrome, patent ductus arteriosus, intraventricular hemorrhage, necrotizing enterocolitis, periventricular leukomalacia, meconium aspiration syndrome, use of surfactant, days of oxygen supplementation, need of vasopressors, length of stay in the neonatal intensive care unit, or postpartum hemorrhage were found. CONCLUSION: MM does not reduce the need for red blood cell transfusions and increases phototherapy requirements in preterm infants.Sin financiación2.095 JCR (2019) Q2, 41/82 Obstetrics & Gynecology0.897 SJR (2019) Q1, 66/395 Radiology, Nuclear Medicine and Imaging, 60/310 Pediatrics, Perinatology and Child Health, 629/2754 Medicine (miscellaneous); Q2, 48/185 Obstetrics and Gynecology, 6/20 EmbryologyNo data IDR 2019UE

2018 Joint European consensus document on the management of antithrombotic therapy in atrial fibrillation patients presenting with acute coronary syndrome and/or undergoing percutaneous cardiovascular interventions: A joint consensus document of the European Heart Rhythm Association (EHRA), European Society of Cardiology Working Group on Thrombosis, European Association of Percutaneous Cardiovascular Interventions (EAPCI), and European Association of Acute Cardiac Care (ACCA) endorsed by the Heart Rhythm Society (HRS), Asia-Pacific Heart Rhythm Society (APHRS), Latin America Heart Rhythm Society (LAHRS), and Cardiac Arrhythmia Society of Southern Africa (CASSA)

In 2014, a joint consensus document dealing with the management of antithrombotic therapy in atrial fibrillation (AF) patients presenting with acute coronary syndrome (ACS) and/or undergoing percutaneous coronary or valve interventions was published, which represented an effort of the European Society of Cardiology Working Group on Thrombosis, European Heart Rhythm Association (EHRA), European Association of Percutaneous Cardiovascular Interventions (EAPCI), and European Association of Acute Cardiac Care (ACCA) endorsed by the Heart Rhythm Society (HRS) and Asia-Pacific Heart Rhythm Society (APHRS). Since publication of this document, additional data from observational cohorts, randomized controlled trials, and percutaneous interventions as well as new guidelines have been published. Moreover, new drugs and devices/interventions are also available, with an increasing evidence base. The approach to managing AF has also evolved towards a more integrated or holistic approach. In recognizing these advances since the last consensus document, EHRA, WG Thrombosis, EAPCI, and ACCA, with additional contributions from HRS, APHRS, Latin America Heart Rhythm Society (LAHRS), and Cardiac Arrhythmia Society of Southern Africa (CASSA), proposed a focused update, to include the new data, with the remit of comprehensively reviewing the available evidence and publishing a focused update consensus document on the management of antithrombotic therapy in AF patients presenting with ACS and/or undergoing percutaneous coronary or valve interventions, and providing up-to-date consensus recommendations for use in clinical practice