8 research outputs found

    Entanglement dynamics under decoherence: from qubits to qudits

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    We investigate the time evolution of entanglement for bipartite systems of arbitrary dimensions under the influence of decoherence. For qubits, we determine the precise entanglement decay rates under different system-environment couplings, including finite temperature effects. For qudits, we show how to obtain upper bounds for the decay rates and also present exact solutions for various classes of states.Comment: 8 pages, 2 figure

    Quantized fields for optimal control in the strong coupling regime

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    We tailor the quantum statistics of a bosonic field to deterministically drive a quantum system into a target state. Experimentally accessible states of the field achieve good control of multi-level or -qubit systems, notably also at coupling strengths beyond the rotating-wave approximation. This extends optimal control theory to the realm of fully quantized, strongly coupled control and target degrees of freedom

    Inelastic chaotic scattering on a Bose-Einstein condensate

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    We devise a microscopic scattering approach to probe the excitation spectrum of a Bose-Einstein condensate. We show that the experimentally accessible scattering cross section exhibits universal Ericson fluctuations, with characteristic properties rooted in the underlying classical field equations.Comment: 11 pages, 5 figure

    Prime and boost aerosol exposure via fog machine or shisha smoke followed by cinnamon hypersensitivity and anaphylaxis to spiced food

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    Background Cinnamon aldehyde (alias cinnamaldehyde) is widely used in food, textile or cosmetic industry. It is mostly associated with contact allergy, but immediate type allergies have been reported. The present study was triggered by a case of anaphylactic events to cinnamon in food and upon skin prick test. We investigated a possible correlation of exposure to a disco fog machine and/or shisha consumption with immediate type hypersensitivity to cinnamon aldehyde in the patient and healthy volunteers.Methods & Results In both fog machines and shisha pipes heating of glycerol-based fluids before evaporation renders chemical transversion to malodorous acrolein. Therefore, both methods are frequently operated with aroma additives. Cinnamon aldehyde and derivatives could be detected by gas chromatography in sampled fog flavored with cola fragrance. The patient as well as healthy (mostly female) volunteers were skin prick tested using cinnamon aldehyde diluted in 0.9 % NaCl, Vaseline® or fog fluid. Persons with a history of exposure to disco fog or shisha (n = 10, mean 32.8 years) reacted with a significantly larger wheal and flare reaction in the skin test (p = 0.0115, p = 0.0146, or p = 0.098) than the non-exposed (n = 8, mean 37.3 years). Both groups were gender matched, but differed in the mean age by 4.5 years. This reaction was specific as compared to skin reactivity to cinnamon alcohol, with only a trend to higher reactivity in exposed persons (ns).Conclusion From our data we conclude that hapten fragrances such as cinnamon aldehyde may during heating in glycerol fluids associate to complete antigens and via inspiration lead to specific immediate type hypersensitivity. In some cases the hypersensitivity may be unmasked by spiced food containing cinnamon aldehyde or related chemicals, and lead to severe adverse reactions. Keywords: Fragrance allergy, Food allergy, Cinnamon aldehyde, Cinnamaldehyde, Type I allergy, Fog machine, Smoke, Shisha, Anaphylaxis, Adverse reaction, Col

    Additional file 1: Figure S1. of Prime and boost aerosol exposure via fog machine or shisha smoke followed by cinnamon hypersensitivity and anaphylaxis to spiced food

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    A) Chemical formulas of substances related to cinnamaldehyde which were related to adverse reactions in the patient; B) Chemical formulas of substances contained in smoke fluids; C) Glycerol can be transformed to acrolein under subtraction of water, and vice versa. (TIF 158 kb

    Scientific Reports / Janus-faced Acrolein prevents allergy but accelerates tumor growth by promoting immunoregulatory Foxp3+ cells: Mouse model for passive respiratory exposure

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    Acrolein, a highly reactive unsaturated aldehyde, is generated in large amounts during smoking and is best known for its genotoxic capacity. Here, we aimed to assess whether acrolein at concentrations relevant for smokers may also exert immunomodulatory effects that could be relevant in allergy or cancer. In a BALB/c allergy model repeated nasal exposure to acrolein abrogated allergen-specific antibody and cytokine formation, and led to a relative accumulation of regulatory T cells in the lungs. Only the acrolein-treated mice were protected from bronchial hyperreactivity as well as from anaphylactic reactions upon challenge with the specific allergen. Moreover, grafted D2F2 tumor cells grew faster and intratumoral Foxp3+ cell accumulation was observed in these mice compared to sham-treated controls. Results from reporter cell lines suggested that acrolein acts via the aryl-hydrocarbon receptor which could be inhibited by resveratrol and 3′-methoxy-4′-nitroflavone Acrolein- stimulation of human PBMCs increased Foxp3+ expression by T cells which could be antagonized by resveratrol. Our mouse and human data thus revealed that acrolein exerts systemic immunosuppression by promoting Foxp3+ regulatory cells. This provides a novel explanation why smokers have a lower allergy, but higher cancer risk.(VLID)486818
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