The role of negative maternal affective states and infant temperament in early interactions between infants with cleft lip and their mothers

OBJECTIVES: The study examined the early interaction between mothers and their infants with cleft lip, assessing the role of maternal affective state and expressiveness and differences in infant temperament. METHODS: Mother-infant interactions were assessed in 25 2-month-old infants with cleft lip and 25 age-matched healthy infants. Self-report and behavioral observations were used to assess maternal depressive symptoms and expressions. Mothers rated infant temperament. RESULTS: Infants with cleft lip were less engaged and their mothers showed more difficulty in interaction than control group dyads. Mothers of infants with cleft lip displayed more negative affectivity, but did not report more self-rated depressive symptoms than control group mothers. No group differences were found in infant temperament. CONCLUSIONS: In order to support the mother's experience and facilitate her ongoing parental role, findings highlight the importance of identifying maternal negative affectivity during early interactions, even when they seem have little awareness of their depressive symptoms

Dealing with Multilingualism in EU Institutions: The Implications of Enlargement from a Managerial Perspective

The European Union is a particularly complex experiment in the management of multilingualism, as compared to other international and supranational organizations, since each Member State has the right to have its own Language recognized as an official language. The 2004 enlargement proved especially challenging, with eight new official languages joining the list. The study compares the ways in which this challenge was met in different EU institutions. Good planning and differentiated managerial solutions, coherent with the mandate and constraints of different institutions, allowed the EU to manage a complex transition in such a way to balance successfully the pressure to control costs and the need to ensure democratic participation to all EU citizens, irrespective of their Language skills

Il ruolo delle risorse immateriali nell'esercizio della funzione di public governance: da modello teorico a pratica gestionale

In ricordo del professor Roberto Gusmani (1935-2009), gi\ue0 Rettore e storico Decano dell'Universit\ue0 di Udine, prestigioso glottologo di fama internazionale e stimatissimo docente nelle Facolt\ue0 di Lingue e di Lettere, \ue8 riunita in quest'opera in due volumi una cospicua serie di rigorosi e importanti saggi, sia di docenti udinesi che di autorevoli studiosi di linguistica italiani e stranieri. Nel primo volume numerosi docenti delle Facolt\ue0 di Lingue e di Lettere dell'Ateneo udinese si sono impegnati, con passione e acribia, nelle rispettive discipline. I saggi cos\uec raccolti spaziano, con rigore e vivacit\ue0, dalla storia alla letteratura inglese, dalla geografia alla letteratura italiana, dalla pedagogia alla letteratura francese. Nel secondo volume (in due tomi) la comunit\ue0 scientifica dei linguisti ha testimoniato con la sua larga e qualificata partecipazione la continuit\ue0 della lezione di Gusmani

Le esperienze europee in materia di fusioni tra Comuni

Ancorch\ue9 le dimensioni medie dei Comuni siano estremamente diverse nei diversi Paesi Membri, il tema delle aggregazioni tra Comuni \ue8 di particolare attualit\ue0 non solo in Italia, ma in tutta Europa. Lo studio confronta le modalit\ue0 di intervento utilizzate dagli otto Paesi europei che tra il 2006 e il 2015, a livello nazionale (Danimarca, Finlandia, Grecia, Lettonia, Olanda) o nell'ambito di specifiche articolazioni subnazionali (Austria, Germania, Regno Unito), sono riusciti a ridurre il numero complessivo di Comuni di almeno il 15%, identificando elementi di comunanza e traiettorie alternative e traendone indicazioni per il caso italiano

a cephalometric intercentre comparison of patients with unilateral cleft lip and palate at 5 and 10 years of age

SUMMARY The aim of this study was to evaluate any differences between the craniofacial growth of unilateral cleft lip and palate (UCLP) patients who underwent surgery in the Milan CLP centre with those from the Oslo CLP centre at 5 and 10 years of age. The Milan sample comprised 88 UCLP patients (60 males, 28 females) at 5 years of age and 26 patients (17 males, 9 females) at 10 years of age all operated on by the same surgeon. The Oslo sample consisted of 48 UCLP patients (26 males, 22 females) aged 5 years and 29 patients (20 males, 9 females) aged 10 years treated by four different surgeons. Lateral cephalometric radiographs obtained for both samples were analysed and angular measurements and ratios were calculated both for the hard and soft tissues. Statistical analysis was undertaken with an unpaired t -test. At 5 years of age, there were neither sagittal nor vertical hard tissue differences between the two groups. With regard to the soft tissues, only the naso-labial angle showed a statistically signifi cant difference (Milan greater than Oslo by 5 degrees, P 2.6 degrees, P 2.9 degrees, P < 0.001, respectively. At 5 years of age, the Milan UCLP sample had the same maxillary protrusion as the Oslo group, while at 10 years of age, the Milan sample were slightly less protruded than the Oslo group

Using new data sources for policymaking

This JRC technical report synthesises the results of our work on using new data sources for policy-making. It reflects a recent shift from more general considerations in the area of Big Data to a more dedicated investigation of Citizen Science, and it summarizes the state of play. With this contribution, we start promoting Citizen Science as an integral component of public participation in policy in Europe. The particular need to focus on the citizen dimension emerged due to (i) the increasing interest in the topic from policy Directorate-Generals (DGs) of the European Commission (EC), (ii) the considerable socio-economic impact policy making has on citizens’ life and society as a whole, and (iii) the clear potentiality of citizens’ contributions to increase the relevance of policy making and the effectiveness of policies when addressing societal challenges. We explicitly concentrate on Citizen Science (or public participation in scientific research) as a way to engage people in practical work, and to develop a mutual understanding between the participants from civil society, research institutions and the public sector by working together on a topic that is of common interest.JRC.B.6-Digital Econom

Epidemiological and Economic Evaluation of a Pilot Prostate Cancer Screening Program

Background. Prostate cancer (PCa) is the second most commonly diagnosed cancer, and the sixth most common killer among men worldwide (Aubry et al., 2013). This research was motivated by the fact that PCa screening continues to be a controversial topic in the Kazakh medical community. This study aimed at description of how newly diagnosed PCa patients are managed in Pavlodar region of the Kazakhstan Republic and at presentation of a budget impact analysis (BIA) for PCa screening program. Also, we aimed to provide a comparative analysis of pricing system on medical services applied in both private and public healthcare sectors of the Kazakhstan Republic. Methods. New cases of PCa have been retrospectively analyzed for the period from January 2013 to December 2017 based on the information obtained from information system "Policlinic" maintained by the Pavlodar regional branch of the Republican Center for Electronic Health and from Cancer Registry of Pavlodar Regional Oncology Center. All data were analyzed with the help of SPSS 20.0 software. Results. The mean age of PCa patients was 68.34 years (SD = 8.559). The government of Kazakhstan invested 20,437,000 KZT (Kazakhstani tenge) in 2017 equivalently 61,188 USD - to fund a pilot study for examination of 9638 men. From 2013 to 2017, out of 49,334 men residing in Pavlodar region of Kazakhstan 1,248 men were diagnosed with prostate diseases, including 130 PCa cases. The PCa detection rate was equal to two cases per month. Only 22.8% of all PCa cases identified in the region within specified time period were revealed as a result of the government-funded PCa screening program. The average prostate cancer detection rate among the target group of Pavlodar region within the period of 5 years was equal to 0.23%. Conclusion. Based on the fact that the PCa screening program failed to enable adequate detection of new PCa cases, we would not recommend to continue this type of screening unless it is undergone careful revision and replanning

Fetal and maternal non-glucose carbohydrates and polyols concentrations in normal human pregnancies at term

The objective of the present investigation was to determine fetal and maternal plasma concentrations of nonglucose carbohydrates and polyols in normal human pregnancies at term. Uncomplicated human pregnancies (n = 50) were studied at > or =37 wk gestation. Blood samples were obtained from umbilical artery, umbilical vein, and maternal peripheral blood at the time of elective cesarean section. Plasma concentrations of inositol, glycerol, erythritol, sorbitol, and mannose were determined by HPLC analysis. Differences between umbilical venous, umbilical arterial, and maternal concentration were tested by the two-tailed t test for paired samples. Correlations between umbilical and maternal concentration and between umbilical venoarterial concentration difference and umbilical arterial concentration were assessed by Pearson's correlation and multiple regression analysis. All newborns were appropriate for gestational age, and oxygenation and acid-base balance were within the normal range for all fetuses studied. For most of the polyols (inositol, sorbitol, and erythritol), the fetal concentration was significantly higher than the maternal concentration. The umbilical venoarterial concentration difference for inositol was -10.5 +/- 3.6 microM, for glycerol was 10 +/- 1.7 microM, for sorbitol was 3.8 +/- 0.5 microM (p < 0.001), and for mannose was 7.6 +/- 0.7 microM. There was a significant correlation between maternal concentration and umbilical venous concentration of mannose (UV(MAN) = 15.38 + 0.69 M(MAN); R(2) = 0.46; p < 0.001). These results indicate that in normal human pregnancies at term, inositol is produced by the fetus, sorbitol is produced by the placenta, and there is a significant umbilical uptake of mannose from the maternal circulation

Epidermoid cyst of the floor of the mouth: two case reports

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