Use of Preputial Skin as Cutaneous Graft after Nevus Excision

We report a four-year-old boy with a nevus covering all the plantar side of his second finger on the left foot. He was also affected by congenital phimosis. Surgical excision of the nevus was indicated, but the skin defect would have been too large to be directly closed. The foreskin was taken as a full-thickness skin graft to cover the cutaneous defect of the finger. The graft intake was favourable and provided a functional repair with good aesthetic characteristic

Iluminación eficiente de la Biblioteca Central de la sede Paseo Colón de la Facultad de Ingeniería de la UBA

Entre los objetivos planteados en tres proyectos UBACYT de investigación consecutivos dedicados a atacar distintos aspectos de “el Uso Eficiente de la Energía Eléctrica” (UEEE) se destacan aquellos ligados al tema de la iluminación. Durante su desarrollo se realizaron numerosas auditorias, en particular en el sector comercial y público, destacándose que el rubro iluminación registra el mayor potencial de ahorro. Teniendo en cuenta los resultados y las recomendaciones efectuadas por estas auditorias se realizaron numerosos trabajos para mejorar la iluminación en la sede Paseo Colón de la Facultad de Ingeniería de la Universidad de Buenos Aires (FIUBA). En esta publicación se describe la metodología adoptada en distintos proyectos, en particular en la sala silenciosa de la Biblioteca Central.Between the objectives raised in three projects consecutive UBACYT of investigation dedicated to attack different aspects from Efficient Energy Use those related to the subject of the illumination stand out. During their development numerous audits were made in individual in the commercial and public sector standing out that the illumination registers the greatest potential of saving. Considering the results and the recommendations conducted in these audits numerous works were made to improve the illumination in the “building Paseo Colon” of the Faculty of Engineering of the University of Buenos Aires (FIUBA). In this publication the methodology adopted in the projects is described and it stands out the last work made on the quiet room of the central library.Asociación Argentina de Energías Renovables y Medio Ambiente (ASADES

Iluminación eficiente de la Biblioteca Central de la sede Paseo Colón de la Facultad de Ingeniería de la UBA

Entre los objetivos planteados en tres proyectos UBACYT de investigación consecutivos dedicados a atacar distintos aspectos de “el Uso Eficiente de la Energía Eléctrica” (UEEE) se destacan aquellos ligados al tema de la iluminación. Durante su desarrollo se realizaron numerosas auditorias, en particular en el sector comercial y público, destacándose que el rubro iluminación registra el mayor potencial de ahorro. Teniendo en cuenta los resultados y las recomendaciones efectuadas por estas auditorias se realizaron numerosos trabajos para mejorar la iluminación en la sede Paseo Colón de la Facultad de Ingeniería de la Universidad de Buenos Aires (FIUBA). En esta publicación se describe la metodología adoptada en distintos proyectos, en particular en la sala silenciosa de la Biblioteca Central.Between the objectives raised in three projects consecutive UBACYT of investigation dedicated to attack different aspects from Efficient Energy Use those related to the subject of the illumination stand out. During their development numerous audits were made in individual in the commercial and public sector standing out that the illumination registers the greatest potential of saving. Considering the results and the recommendations conducted in these audits numerous works were made to improve the illumination in the “building Paseo Colon” of the Faculty of Engineering of the University of Buenos Aires (FIUBA). In this publication the methodology adopted in the projects is described and it stands out the last work made on the quiet room of the central library.Asociación Argentina de Energías Renovables y Medio Ambiente (ASADES

Iluminación eficiente de la Biblioteca Central de la sede Paseo Colón de la Facultad de Ingeniería de la UBA

Entre los objetivos planteados en tres proyectos UBACYT de investigación consecutivos dedicados a atacar distintos aspectos de “el Uso Eficiente de la Energía Eléctrica” (UEEE) se destacan aquellos ligados al tema de la iluminación. Durante su desarrollo se realizaron numerosas auditorias, en particular en el sector comercial y público, destacándose que el rubro iluminación registra el mayor potencial de ahorro. Teniendo en cuenta los resultados y las recomendaciones efectuadas por estas auditorias se realizaron numerosos trabajos para mejorar la iluminación en la sede Paseo Colón de la Facultad de Ingeniería de la Universidad de Buenos Aires (FIUBA). En esta publicación se describe la metodología adoptada en distintos proyectos, en particular en la sala silenciosa de la Biblioteca Central.Between the objectives raised in three projects consecutive UBACYT of investigation dedicated to attack different aspects from Efficient Energy Use those related to the subject of the illumination stand out. During their development numerous audits were made in individual in the commercial and public sector standing out that the illumination registers the greatest potential of saving. Considering the results and the recommendations conducted in these audits numerous works were made to improve the illumination in the “building Paseo Colon” of the Faculty of Engineering of the University of Buenos Aires (FIUBA). In this publication the methodology adopted in the projects is described and it stands out the last work made on the quiet room of the central library.Asociación Argentina de Energías Renovables y Medio Ambiente (ASADES

ClC-1 mutations in myotonia congenita patients: insights into molecular gating mechanisms and genotype-phenotype correlation

Loss-of-function mutations of the skeletal muscle ClC-1 channel cause myotonia congenita with variable phenotypes. Using patch clamp we show that F484L, located in the conducting pore, probably induces mild dominant myotonia by right-shifting the slow gating of ClC-1 channel, without exerting a dominant-negative effect on the wild-type (WT) subunit. Molecular dynamics simulations suggest that F484L affects the slow gate by increasing the frequency and the stability of H-bond formation between E232 in helix F and Y578 in helix R. Three other myotonic ClC-1 mutations are shown to produce distinct effects on channel function: L198P shifts the slow gate to positive potentials, V640G reduces channel activity, while L628P displays a WT-like behaviour (electrophysiology data only). Our results provide novel insight into the molecular mechanisms underlying normal and altered ClC-1 function

Developing the islamic financial services sector in Italy: An institutional theory perspective

© The Editor(s) (if applicable) and the Author(s) 2016. The Islamic Financial Services (IFS) sector has experienced wider consumer acceptance and rapid growth since its commercial launch in the 1970s. This growth has primarily been in countries in Asia such as Iran, Malaysia, Pakistan and the Middle East region. Although non-Muslim majority countries like Hong Kong and Singapore have taken positive strides in developing the sector, European countries have lagged behind their Asian counterparts (Daily Times, 2013). Europe is host to a large Muslim population, but the lack of developed Islamic financial institutions means that the potential of IFS product offerings is yet to be fully realized in the region (Volk and Pudelko, 2010)

Envelhecimento (in)ativo e desenvolvimento emocional em reclusos

Este projeto pretende apresentar o contributo do programa de Exercício Físico e do Desenvolvimento Emocional nos reclusos. Para isso optamos por desenvolver um estudo de carácter Quantitativo, Exploratório, Quasi - Experimental, Longitudinal e Descritivo. A amostra é constituída por 20 reclusos do Estabelecimento Prisional de Izeda, com idade média de 41,10±10,19 anos, distribuída entre os 24 e os 67 anos. Dos 20 reclusos, 9 foram designados para integrarem o Grupo de Investigação e os restantes o Grupo de Controlo. A seleção foi feita de forma aleatória. O Grupo de Investigação foi submetido a um programa de atividades de duas a três sessões semanais, durante 8 semanas, tendo cada sessão a duração de 1:15 Horas. Foi aplicada a escala EVCE e o questionário SF-36v2, com a complementaridade das avaliações do estado funcional dos reclusos. As características psicométrica obtidas na escala EVCE e no questionário SF-36v2 permitem-nos verificar que neste estudo se obtem uma boa consistência interna. Após a realização das sessões de intervenção, verificamos que não houve alterações estatisticamente significativas entre os parâmetros do Grupo de Controlo e o Grupo de Investigação. Desta forma, podemos concluir que o programa de intervenção teria melhores resultados se tivesse uma duração maior ao longo do tempo.This project aims to present the contribution of an Exercise Program and of an Emotional Development Program in prison. For this study we chose to develop a Quantitative Explorational, Quasi - Experimental, Descriptive and Longitudinal. The sample consists of 20 inmates of the Izeda Prison, with a mean age of 41.10± 10.19 years, distributed between 24 and 67 years. Of the 20 inmates, nine were appointed to serve on the Research Group and the remaining To the Control Group. The selection was done randomly. The Research Group has undergone program of activities two to three times per week for 8 weeks, with each session lasting 1h15m. EVCE scale and SF-36v2 were applied, the functional status of the inmates was assessed. The psychometric characteristics obtained in EVCE scale and SF-36v2 allow us to verify that this study gives a good internal consistency. After completion of intervention sessions, we found that there were no statistically significant changes between the parameters of the Control Group and Research Group. Thus, we can conclude that the intervention program would have better results if it had a longer duration over tim

The clinical utility of molecular diagnostic testing for primary immune deficiency disorders: a case based review

Primary immune deficiency disorders (PIDs) are a group of diseases associated with a genetic predisposition to recurrent infections, malignancy, autoimmunity and allergy. The molecular basis of many of these disorders has been identified in the last two decades. Most are inherited as single gene defects. Identifying the underlying genetic defect plays a critical role in patient management including diagnosis, family studies, prognostic information, prenatal diagnosis and is useful in defining new diseases. In this review we outline the clinical utility of molecular testing for these disorders using clinical cases referred to Auckland Hospital. It is written from the perspective of a laboratory offering a wide range of tests for a small developed country

The primary headaches: genetics, epigenetics and a behavioural genetic model

The primary headaches, migraine with (MA) and without aura (MO) and cluster headache, all carry a substantial genetic liability. Familial hemiplegic migraine (FHM), an autosomal dominant mendelian disorder classified as a subtype of MA, is due to mutations in genes encoding neural channel subunits. MA/MO are considered multifactorial genetic disorders, and FHM has been proposed as a model for migraine aetiology. However, a review of the genetic studies suggests that the FHM genes are not involved in the typical migraines and that FHM should be considered as a syndromic migraine rather than a subtype of MA. Adopting the concept of syndromic migraine could be useful in understanding migraine pathogenesis. We hypothesise that epigenetic mechanisms play an important role in headache pathogenesis. A behavioural model is proposed, whereby the primary headaches are construed as behaviours, not symptoms, evolutionarily conserved for their adaptive value and engendered out of a genetic repertoire by a network of pattern generators present in the brain and signalling homeostatic imbalance. This behavioural model could be incorporated into migraine genetic research