Avian lens spectrin: subunit composition compared with erythrocyte and brain spectrin

Chicken lens spectrin is composed predominantly of equimolar amounts of two polypeptides with solubility properties similar, but not identical, to erythrocyte spectrin. The larger polypeptide, Mr 240,000 (lens alpha- spectrin), co-migrates with erythrocyte and brain alpha-spectrin on one- and two-dimensional SDS polyacrylamide gels and cross-reacts with antibodies specific for chicken erythrocyte alpha-spectrin; the smaller polypeptide, Mr 235,000 (lens gamma-spectrin), co-migrates with brain gamma-spectrin and does not cross-react with either the alpha-spectrin antibodies specific for chicken erythrocyte beta-spectrin. Minor amounts of polypeptides antigenically related to erythrocyte beta- spectrin with a greater electrophoretic mobility than lens gamma- spectrin are also detected in lens. The equimolar ratio of lens alpha- and gamma-spectrin is invariantly maintained during the extraction of lens plasma membranes under different conditions, or after immunoprecipitation of whole extracts of lens with erythrocyte alpha- spectrin antibodies. Two-dimensional peptide mapping reveals that whereas alpha-spectrins from chicken erythrocytes, brain, and lens are highly homologous, the gamma-spectrins, although related, have some cell-type-specific peptides and are substantially different from erythrocyte beta-spectrin. Thus, the expression of cell-type-specific gamma- and beta-spectrins may be the basis for the assembly of a spectrin-plasma membrane complex whose molecular composition is tailored to the functional requirements of the particular cell-type

A circumpolar perspective on fluvial sediment flux to the Arctic ocean

Quantification of sediment fluxes from rivers is fundamental to understanding land‐ocean linkages in the Arctic. Numerous publications have focused on this subject over the past century, yet assessments of temporal trends are scarce and consensus on contemporary fluxes is lacking. Published estimates vary widely, but often provide little accessory information needed to interpret the differences. We present a pan‐arctic synthesis of sediment flux from 19 arctic rivers, primarily focusing on contributions from the eight largest ones. For this synthesis, historical records and recent unpublished data were compiled from Russian, Canadian, and United States sources. Evaluation of these data revealed no long‐term trends in sediment flux, but did show stepwise changes in the historical records of two of the rivers. In some cases, old values that do not reflect contemporary fluxes are still being reported, while in other cases, typographical errors have been propagated into the recent literature. Most of the discrepancy among published estimates, however, can be explained by differences in years of records examined and gauging stations used. Variations in sediment flux from year to year in arctic rivers are large, so estimates based on relatively few years can differ substantially. To determine best contemporary estimates of sediment flux for the eight largest arctic rivers, we used a combination of newly available data, historical records, and literature values. These estimates contribute to our understanding of carbon, nutrient, and contaminant transport to the Arctic Ocean and provide a baseline for detecting future anthropogenic or natural change in the Arctic

Respiratory Obstruction Resulting in Death: Case Report With Necropsy Findings

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ESTIMATING THE VALUE OF SEQUENTIAL UPDATING SOLUTIONS FOR INTRAYEAR CROP MANAGEMENT

Results of comparing updating versus nonupdating modeling assumptions call into question the use of models based on nonupdating strategies as valid representations of actual farmer actions. If farmers are sequential updaters, the results indicate that models assuming no updating are inaccurate. The degree of this inaccuracy ranges between 4% and 10% of profits for the study area. Further, the results indicate that updating appears to be important for both descriptive and prescriptive studies of farmer behavior.Crop Production/Industries,

BIOPHYSICAL SIMULATION IN SUPPORT OF CROP PRODUCTION DECISIONS: A CASE STUDY IN THE BLACKLANDS REGION OF TEXAS

Economic feasibility of Texas Blacklands corn production in relation to sorghum, wheat, and cotton is studied. Biophysical simulation generated yield data are integrated with an economic decision model using quadratic programming. Given the various scenarios analyzed, corn is economically feasible for the Blacklands. A crop mix of half corn and half cotton production is selected under risk neutrality with wheat entering if risk aversion is present. Corn and grain sorghum production are highly substitutable. Profit effects attributed to changing corn planting dates are more pronounced than profit changes resulting from altering corn population or maturity class.Crop Production/Industries,

Intelligence/Electronic Warfare (IEW) direction-finding and fix estimation analysis report. Volume 2: Trailblazer

An analysis of the direction finding (DF) and fix estimation algorithms in TRAILBLAZER is presented. The TRAILBLAZER software analyzed is old and not currently used in the field. However, the algorithms analyzed are used in other current IEW systems. The underlying algorithm assumptions (including unmodeled errors) are examined along with their appropriateness for TRAILBLAZER. Coding and documentation problems are then discussed. A detailed error budget is presented

COMBINING ECONOMIC AND BIOLOGICAL DATA TO ESTIMATE THE IMPACT OF POLLUTION ON CROP PRODUCTION

Duality methods utilizing a profit function framework are employed to estimate the output elasticity of ambient ozone levels on cash grain farms in Illinois. While duality methods have been recommended as a cure to many of the statistical problems of direct estimation of production functions, multicollinearity may still be a problem. A method for utilizing stochastic information on parameters of a seemingly unrelated system of equations, which is implied by profit function estimation, is developed and applied to measuring the impact of ozone. Such an approach may be necessary in measuring other environmental effects because of a lack of regressor variability.Crop Production/Industries, Environmental Economics and Policy,

Axillary nodal metastasis at primary presentation of an oropharyngeal primary carcinoma: a case report and review of the literature

<p>Abstract</p> <p>Introduction</p> <p>Axillary nodal metastasis is very rare in head and neck squamous cell carcinoma. The few cases reported in the literature all involve patients who have previously undergone either neck dissection alone, or neck dissection and radiotherapy to the neck, and subsequently develop delayed recurrences of disease, with axillary nodal involvement.</p> <p>Case presentation</p> <p>We present the case of a 62-year-old man of Cape Malay ethnicity, who presented with an oropharyngeal squamous cell carcinoma, and cervical and axillary nodal metastasis at primary presentation.</p> <p>Conclusion</p> <p>Whilst previous reports in the literature suggest routine examination of the axilla is advisable in patients with previously treated neck cancer and recurrence of head and neck cancer, we propose that the axilla should be routinely examined in new cases, particularly when there is involvement of the level 5 nodes.</p