Synchronised neural signature of creative mental imagery in reality and augmented reality

Creativity, transforming imaginative thinking into reality, is a mental imagery simulation in essence. It can be incorporeal, concerns sophisticated and/or substantial thinking, and involves objects. In the present study, a mental imagery task consisting of creating a scene using familiar (FA) or abstract (AB) physical or virtual objects in real (RMI) and augmented reality (VMI) environments, and an execution task involving effectively creating a scene in augmented reality (VE), were utilised. The beta and gamma neural oscillations of healthy participants were recorded via a 32 channel wireless 10/20 international EGG system. In real and augmented environments and for both the mental imagery and execution tasks, the participants displayed a similar cortico-cortical neural signature essentially based on synchronous vs asynchronous beta and gamma oscillatory activities between anterior (i.e. frontal) and posterior (i.e. parietal, occipito-parietal and occipito-temporal) areas bilaterally. The findings revealed a transient synchronised neural architecture that appears to be consistent with the hypothesis according to which, creativity, because of its inherent complexity, cannot be confined to a single brain area but engages various interconnected networks

Certifying forest-based ecosystem services: results from the world-first application of the FSC ecosystem service procedure in Italy

In recent years, several mechanisms have been put in practice to value forest-based ecosystem services in order to maintain or enhance their provision. Mechanisms range from more traditional - e.g. regulation of land use, taxes and subsidies - to more innovative market-based ones such as Payments for Ecosystem Services (PES). More recently, the use of voluntary third-party forest certification schemes based on standards and procedures specifically aimed at considering the provision of ecosystem services has gained interests. Certification schemes have already been established for specific ecosystem services, in particular focusing on carbon, in some cases including biodiversity conservation as a co-benefit. The Forest Stewardship Council\uae (FSC) is currently the only scheme promoting the certification of multiple ecosystem services by demonstrating the positive impacts of FSC-certified forest management practices on five regulating and cultural services. A dedicated procedure has been developed, that allows the assessment of the impact of forest management on carbon sequestration and storage, biodiversity conservation, watershed services, soil conservation and recreational services, by means of specific methodologies and indicators. We critically analyzed the world-first application of the FSC ecosystem services certification procedure with reference to the forest certification group Waldplus and Associazione Forestale di Pianura (Lowland Forest Association) in northern Italy. The case study includes 1,043 hectares of different forest types, from semi-natural productive forests to conservation forests, traditionally managed to deliver multiple benefits. Our objective is to give insights that could inform and improve future developments in the field of certification, promotion and marketing of ecosystem services

A multi-objective-based approach for Fair Principal Component Analysis

In dimension reduction problems, the adopted technique may produce disparities between the representation errors of two or more different groups. For instance, in the projected space, a specific class can be better represented in comparison with the other ones. Depending on the situation, this unfair result may introduce ethical concerns. In this context, this paper investigates how a fairness measure can be considered when performing dimension reduction through principal component analysis. Since both reconstruction error and fairness measure must be taken into account, we propose a multi-objective-based approach to tackle the Fair Principal Component Analysis problem. The experiments attest that a fairer result can be achieved with a very small loss in the reconstruction error

Instruments politiques pour la préservation ou la restauration des espaces boisés et l’amélioration de la fourniture de biens et services forestiers

Dans la région méditerranéenne, les décideurs et les gestionnaires d’espaces forestiers cherchent des instruments politiques afin de combler l’écart entre la rentabilité financière et la rentabilité économique dans la gestion forestière. L’article passe en revue ces instruments politiques en se concentrant sur les instruments fondés sur le marché et plus particulièrement sur les paiements pour services environnementaux (PSE). Il est question notamment des problèmes de mise en œuvre des systèmes de PSE, en reconsidérant les obstacles et les opportunités offertes à leur développement dans la région méditerranéenne

Policy instruments to preserve or restore woodlands and to improve the supply of forest goods and services

In the Mediterranean region, policy makers and forest managers are seeking for policy instruments to fill the gap between financial and economic profitability in forest management. This paper reviews these policy instruments focusing on the market-based instruments and specifically on payments for environmental service (PES). We focus on the implementation problems of PES schemes looking at barriers and opportunities offered to their development in the Mediterranean region

cranial nerve abnormalities in oculo auriculo vertebral spectrum

BACKGROUND AND PURPOSE: Cranial nerve abnormalities might be observed in hemifacial microsomia and microtia (oculo-auriculo-vertebral spectrum), but the rate, features, and relationship with functional impairment or phenotype severity have not yet been defined. This study aimed at investigating absence/asymmetry, abnormal origin, morphology and course of cranial nerves, and presence/asymmetry of the foramen ovale and inferior alveolar nerve canal in a cohort of oculo-auriculo-vertebral spectrum patients. MATERIALS AND METHODS: Twenty-nine patients with oculo-auriculo-vertebral spectrum (mean age, 7 years; age range, 0.2–31 years; 12 females) underwent brain MR imaging, CT, and neurologic evaluation; 19 patients had a more severe phenotype (Goldenhar syndrome). RESULTS: Cranial nerve abnormalities were detected only in patients with Goldenhar syndrome (17/19, bilaterally in 8) and were involved the second (4/19), third (1/18), fifth (11/19), sixth (8/16), seventh (11/18), and eighth (8/18) cranial nerves. Multiple cranial nerve abnormalities were common (11/17). Eleven patients showed bone foramina abnormalities. Trigeminal and facial nerve dysfunctions were common (44% and 58%, respectively), especially in patients with Goldenhar syndrome. Trigeminal abnormalities showed a good correlation with ipsilateral dysfunction ( P = .018), which further increased when bone foramina abnormalities were included. The facial nerve showed a trend toward correlation with ipsilateral dysfunction ( P = .081). Diplopia was found only in patients with Goldenhar syndrome and was associated with third and sixth cranial nerve abnormalities ( P = .006). CONCLUSIONS: Among patients with oculo-auriculo-vertebral spectrum, cranial nerve morphologic abnormalities are common, correlate with phenotype severity, and often entail a functional impairment. The spectrum of cranial nerve abnormalities appears wider than simple hypo-/aplasia and includes an anomalous cisternal course and partial/complete fusion of diverse cranial nerves. CN : cranial nerve OAVS : oculo-auriculo-vertebral spectru

Fibroblast Growth Factor 23 Does Not Directly Influence Skeletal Muscle Cell Proliferation and Differentiation or Ex Vivo Muscle Contractility

Skeletal muscle dysfunction accompanies the clinical disorders of chronic kidney disease (CKD) and hereditary hypophosphatemic rickets. In both disorders, fibroblast growth factor 23 (FGF23), a bone-derived hormone regulating phosphate and vitamin D metabolism, becomes chronically elevated. FGF23 has been shown to play a direct role in cardiac muscle dysfunction; however, it is unknown whether FGF23 signaling can also directly induce skeletal muscle dysfunction. We found expression of potential FGF23 receptors ( Fgfr1-4) and α-Klotho in muscles of two animal models (CD-1 and Cy/+ rat, a naturally occurring rat model of chronic kidney disease-mineral bone disorder) as well as C2C12 myoblasts and myotubes. C2C12 proliferation, myogenic gene expression, oxidative stress marker 8-OHdG, intracellular Ca2+ ([Ca2+]i), and ex vivo contractility of extensor digitorum longus (EDL) or soleus muscles were assessed after treatment with various amounts of FGF23. FGF23 (2-100 ng/ml) did not alter C2C12 proliferation, expression of myogenic genes, or oxidative stress after 24- to 72-h treatment. Acute or prolonged FGF23 treatment up to 6 days did not alter C2C12 [Ca2+]i handling, nor did acute treatment with FGF23 (9-100 ng/ml) affect EDL and soleus muscle contractility. In conclusion, although skeletal muscles express the receptors involved in FGF23-mediated signaling, in vitro FGF23 treatments failed to directly alter skeletal muscle development or function under the conditions tested. We hypothesize that other endogenous substances may be required to act in concert with FGF23 or apart from FGF23 to promote muscle dysfunction in hereditary hypophosphatemic rickets and CKD

Correspondence Between Cognitive and Audiological Evaluations Among the Elderly: A Preliminary Report of an Audiological Screening Model of Subjects at Risk of Cognitive Decline With Slight to Moderate Hearing Loss

Epidemiological studies show increasing prevalence rates of cognitive decline and hearing loss with age, particularly after the age of 65 years. These conditions are reported to be associated, although conclusive evidence of causality and implications is lacking. Nevertheless, audiological and cognitive assessment among elderly people is a key target for comprehensive and multidisciplinary evaluation of the subject's frailty status. To evaluate the use of tools for identifying older adults at risk of hearing loss and cognitive decline and to compare skills and abilities in terms of hearing and cognitive performances between older adults and young subjects, we performed a prospective cross-sectional study using supraliminal auditory tests. The relationship between cognitive assessment results and audiometric results was investigated, and reference ranges for different ages or stages of disease were determined. Patients older than 65 years with different degrees of hearing function were enrolled. Each subject underwent an extensive audiological assessment, including tonal and speech audiometry, Italian Matrix Sentence Test, and speech audiometry with logatomes in quiet. Cognitive function was screened and then verified by experienced clinicians using the Montreal Cognitive Assessment Score, the Geriatric Depression Scale, and further investigations in some. One hundred twenty-three subjects were finally enrolled during 2016-2019: 103 were >65 years of age and 20 were younger participants (as controls). Cognitive functions showed a correlation with the audiological results in post-lingual hearing-impaired patients, in particular in those affected by slight to moderate hearing loss and aged more than 70 years. Audiological testing can thus be useful in clinical assessment and identification of patients at risk of cognitive impairment. The study was limited by its sample size (CI 95%; CL 10%), strict dependence on language, and hearing threshold. Further investigations should be conducted to confirm the reported results and to verify similar screening models