717 research outputs found
Seasonal Climate Forecasts and Risk Management Among Georgia Farmers
Recent increases in the scientific robustness of seasonal climate forecasts have not led to substantial changes in farmers’ risk management strategies of actors, largely because there is poor integration of scientific forecasting into farmers’ decision-making processes. The goal of the research presented here is to explore the potentials and constraints for farmers’ application of seasonal climate forecasts through an analysis of the cultural contexts of their decision-making and information use. Semi-structured interviews were conducted with 38 farmers in southern Georgia, examining their approaches, risk-management, to livelihood goals and strategies, and interactions with weather and climate information. Findings indicate that farmers’ management of risks associated with climate variability is embedded within a broad array of social factors, including subjective construction of social and personal identities, goals, and values. These cultural contexts affect the ways that farmers interpret and might apply seasonal climate forecasts to agricultural decisions. These findings indicate that, rather than simply acting as a technical information input, seasonal climate forecasts and forecasters must gradually work theirway into farmers’ trusted social networks before their potential as risk management tools will be realized. Furthermore, while seeking to produce scientific information to support farmers’ adaptive practices, scientists themselves must adapt their own practices to better fit a coproduction of knowledge approach
Shuttle orbiter Ku-band radar/communications system design evaluation
Tasks performed in an examination and critique of a Ku-band radar communications system for the shuttle orbiter are reported. Topics cover: (1) Ku-band high gain antenna/widebeam horn design evaluation; (2) evaluation of the Ku-band SPA and EA-1 LRU software; (3) system test evaluation; (4) critical design review and development test evaluation; (5) Ku-band bent pipe channel performance evaluation; (6) Ku-band LRU interchangeability analysis; and (7) deliverable test equipment evaluation. Where discrepancies were found, modifications and improvements to the Ku-band system and the associated test procedures are suggested
Where do graduates Develop their Enterprise Skills? The Value of the Contribution of Higher Education Institutions’ Context
This study investigates the value of the contribution of HEIs’ context in developing graduates enterprise skills. HEIs are under pressure to develop more enterprising graduates, particularly with the increasing numbers of graduates seeking employment and the growing dissatisfaction of employers. This study explores where graduates develop enterprise skills through investigating the impact of HE and employment contexts on their development. The paper draws on a qualitative study in the social constructionist paradigm within the pharmacy context, where interviews were conducted with pharmacy academics and employers. Results show that ability to demonstrate skills in one context does not necessarily mean ability to demonstrate them in another since the development and demonstration of enterprise skills is impacted by the contexts in which they are developed and demonstrated. The study adds value by highlighting the significant role of both HE and employment contexts in developing enterprise skills, while emphasising that these skills become more transferable through exposure to more contexts
Neurite orientation and dispersion density imaging (NODDI) detects cortical and corticospinal tract degeneration in ALS
Background: Corticospinal tract (CST) degeneration and cortical atrophy are consistent features of amyotrophic lateral sclerosis (ALS). We hypothesised that neurite orientation dispersion and density imaging (NODDI), a multicompartment model of diffusion MRI, would reveal microstructural changes associated with ALS within the CST and precentral gyrus (PCG) ‘in vivo’.
Methods: 23 participants with sporadic ALS and 23 healthy controls underwent diffusion MRI. Neurite density index (NDI), orientation dispersion index (ODI) and free water fraction (isotropic compartment (ISO)) were derived. Whole brain voxel-wise analysis was performed to assess for group differences. Standard diffusion tensor imaging (DTI) parameters were computed for comparison. Subgroup analysis was performed to investigate for NODDI parameter differences relating to bulbar involvement. Correlation of NODDI parameters with clinical variables were also explored. The results were accepted as significant where p<0.05 after family-wise error correction at the cluster level, clusters formed with p<0.001.
Results: In the ALS group NDI was reduced in the extensive regions of the CST, the corpus callosum and the right PCG. ODI was reduced in the right anterior internal capsule and the right PCG. Significant differences in NDI were detected between subgroups stratified according to the presence or absence of bulbar involvement. ODI and ISO correlated with disease duration.
Conclusions: NODDI demonstrates that axonal loss within the CST is a core feature of degeneration in ALS. This is the main factor contributing to the altered diffusivity profile detected using DTI. NODDI also identified dendritic alterations within the PCG, suggesting microstructural cortical dendritic changes occur together with CST axonal damage
Participatory scenario development for environmental management:A methodological framework illustrated with experience from the UK uplands
A methodological framework is proposed for participatory scenario development on the basis of evidence from the literature, and is tested and refined through the development of scenarios for the future of UK uplands. The paper uses a review of previous work to justify a framework based around the following steps: i) define context and establish whether there is a basis for stakeholder engagement in scenario development; ii) systematically identify and represent relevant stakeholders in the process; iii) define clear objectives for scenario development with stakeholders including spatial and temporal boundaries; iv) select relevant participatory methods for scenario development, during initial scenario construction, evaluation and to support decision-making based on scenarios; and v) integrate local and scientific knowledge throughout the process. The application of this framework in case study research suggests that participatory scenario development has the potential to: i) make scenarios more relevant to stakeholder needs and priorities; ii) extend the range of scenarios developed; iii) develop more detailed and precise scenarios through the integration of local and scientific knowledge; and iv) move beyond scenario development to facilitate adaptation to future change. It is argued that participatory scenario development can empower stakeholders and lead to more consistent and robust scenarios that can help people prepare more effectively for future change
Climate Clever Beef : On-farm demonstration of adaptation and mitigation options for climate change in northern Australia
This project engaged with beef producers in five regions of northern Australia to identify management options that improve the performance and resilience of beef businesses. The work was done in the context of increasing the resilience of businesses to current climate variability as well as to projected changes in climate. The project also identified potential synergies and conflicts between improved business performance, climate adaptation practices and greenhouse gas emissions management.
Three regions (Qld Gulf, Fitzroy Basin and Victoria River District) evaluated climate adaptation and greenhouse gas mitigation options via a benchmarking and options analysis approach with three “focal” properties. Five indicators of performance were evaluated for each property – profitability, productivity, land condition, climate change risk and greenhouse gas emissions. These detailed business analyses were complemented by demonstration sites in each region. Two other regions (Qld Mitchell grasslands and NT Barkly Tablelands) used on-property demonstration sites to showcase promising climate adaptation practices identified in a previous project.
The focal property approach provided a systematic process for assessing current business performance as well as a ready means of estimating the impacts of management changes. For example, over a 15 year period, the Qld Gulf focal property improved its pasture condition dramatically by stocking around the long-term carrying capacity and undertaking wet season spelling. This, combined with herd management improvements, increased profitability and productivity, reduced greenhouse gas emissions by 15%, and improved greenhouse gas emission efficiency by >100%.
The demonstration sites in each region effectively promoted and documented the benefits of key grazing practices for improving resilience to both current climate variability and potential climate change. For example, on a 16,118km² property in the Barkly, a paddock demonstration has documented initial land condition recovery at old bores, and the reduced risk of overgrazing around new bores, through best practice stocking rate management and wet season spelling.
Qualitative analyses showed that many of the adaptation practices identified for improving resilience are consistent with existing best practice recommendations aimed at improving productivity and sustainability. Furthermore, these adaptation practices appear to have largely neutral implications for greenhouse gas emissions. In contrast, practices and options for reducing greenhouse gas emissions were more likely to create conflicts that leave enterprises more vulnerable to climate change. Examples of the negative consequences of mitigation measures include reduced pasture production associated with increased carbon sequestration in trees (i.e. woody vegetation thickening or regrowth retention) and increased operating costs associated with carbon pricing (if these are not offset with carbon credits).
The project demonstration sites and focal property benchmarking process provided a solid base for focussed extension work targeting the drivers of profit, land condition, greenhouse gas emissions intensity and climate adaptation strategies
Liberal intervention in the foreign policy thinking of Tony Blair and David Cameron
David Cameron was a critic of Tony Blair’s doctrine of the international community, which was used to justify war in Kosovo and more controversially in Iraq, suggesting caution in projecting military force abroad while in opposition. However, and in spite of making severe cuts to the defence budget, the Cameron-led Coalition government signed Britain up to a military intervention in Libya within a year of coming into office. What does this say about the place liberal interventionism occupies in contemporary British foreign policy? To answer this question, this article studies the nature of what we describe as the ‘bounded liberal’ tradition that has informed British foreign policy thinking since 1945, suggesting that it puts a distinctly UK national twist on conventional conservative thought about international affairs. Its components are: scepticism of grand schemes to remake the world; instinctive Atlanticism; security through collective endeavour; and anti-appeasement. We then compare and contrast the conditions for intervention set out by Tony Blair and David Cameron. We explain the similarities but crucially also the vital differences between the two leaders’ thinking on intervention, with particular reference to Cameron’s perception that Downing Street needed to loosen its control over foreign policy-making after Iraq. Our argument is that policy substance, policy style and party political dilemmas prompted Blair and Cameron to reconnect British foreign policy with its ethical roots, ingraining a bounded liberal posture to British foreign policy after the moral bankruptcy of the John Major years. This return to a patient, pragmatic and ethically informed foreign policy meant that military operations in Kosovo and Libya were undertaken in quite different circumstances, yet came to be justified by similar arguments from the two leaders
'Sexercise': Working out heterosexuality in Jane Fonda’s fitness books
This is an Author's Accepted Manuscript of an article published in Leisure Studies, 30(2), 237 - 255, 2011, copyright Taylor & Francis, available online at: http://www.tandfonline.com/10.1080/02614367.2010.523837.This paper explores the connection between the promotion of heterosexual norms in women’s fitness books written by or in the name of Jane Fonda during the 1980s and the commodification of women’s fitness space in both the public and private spheres. The paper is set in the absence of overt discussions of normative heterosexuality in leisure studies and draws on critical heterosexual scholarship as well as the growing body of work theorising geographies of corporeality and heterosexuality. Using the principles of media discourse analysis, the paper identifies three overlapping characteristics of heterosexuality represented in Jane Fonda’s fitness books, and embodied through the exercise regimes: respectable heterosexual desire, monogamous procreation and domesticity. The paper concludes that the promotion and prescription of exercise for women in the Jane Fonda workout books centred on the reproduction and embodiment of heterosexual corporeality. Set within an emerging commercial landscape of women’s fitness in the 1980s, such exercise practices were significant in the legitimation and institutionalisation of heteronormativity
The Effects of Serotonin Receptor Antagonists on Contraction and Relaxation Responses Induced by Electrical Stimulation in the Rat Small Intestine
Background: The main source of 5-HT in body is in enterchromafin cells of intestine, different studies mentioned different roles for endogenous 5-HT and receptors involved and it is not clearified the mechanism of action of endogenous 5-HT.
Objectives: To study the role of endogenous 5-HT on modulation of contraction and relaxation responses induced by electrical field stimulation (EFS) in different regions of the rat intestine.
Materials and Methods: Segments taken from the rat duodenum, jejunum, mid and terminal ileum were vertically mounted, connected to a transducer and exposed to EFS with different frequencies in the absence and presence of various inhibitors of enteric mediators i. e. specific 5-HT receptor antagonists.
Results: EFS-induced responses were sensitive to TTX and partly to atropine, indicating a major neuronal involvement and a cholinergic system. Pre-treatment with WAY100635 (a 5-HT1A receptor antagonist) and granisetron up to 10.0 µM, GR113808 (a 5-HT4 receptor antagonist), methysergide and ritanserin up to 1.0 µM, failed to modify responses to EFS inall examined tissues. In the presence of SB258585 1.0 µM (a 5-HT6 receptor antagonist) there was a trend to enhance contraction in the proximal part of the intestine and reduce contraction in the distal part. Pre-treatment with SB269970A 1.0 µM (5-HT7 receptor antagonist) induced a greater contractile response to EFS at 0.4 Hz only in the duodenum.
Conclusions: The application of 5-HT1A, 5-HT2, 5-HT3, 5-HT4, 5-HT6 and 5-HT7 receptor antagonists, applied at concentrations lower than 1.0 µM did not modify the EFS-induced contraction and relaxation responses, whichsuggests the unlikely involvement of endogenous 5-HT in mediating responses to EFS in the described test conditions.
Keywords: Electric Stimulation Therapy; Serotonin 5-HT1 Receptor Antagonists; Intestine, Smal
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