10,468 research outputs found
Integrating research with NHS clinical practice: Unwelcome intrusion or constructive triangulation?
When embarking on research into the effectiveness of psychoanalytic psychotherapy in the NHS or the application of psychoanalytic principles, researchers come up against a number of hurdles: many clinicians still see empirical research as antithetical or disruptive to the practice of psychoanalytic psychotherapy; psychoanalytic psychotherapy has previously fared poorly in evidence-based policy guidelines and this can discourage ambition, and there are technical problems of research design, measurement and standardization. Nevertheless, in a political climate which stresses service evaluation, measurable outcomes and empirical evidence, psychoanalytic psychotherapy must participate to survive. There may be gains from conducting research beyond simply meeting the requirement to provide evidence of effectiveness. Research may be viewed by some clinicians as an unwelcome intruder but it may have the potential to offer triangulation, the perspective of the 'third', and so strengthen the foundations of clinical practice and the development of psychoanalytic thought
Room temperature spin relaxation in GaAs/AlGaAs multiple quantum wells
We have explored the dependence of electron spin relaxation in undoped GaAs/AlGaAs quantum wells on well width (confinement energy) at 300 K. For wide wells, the relaxation rate tends to the intrinsic bulk value due to the D'yakonov-Perel (DP) mechanism with momentum scattering by phonons. In narrower wells, there is a strong dependence of relaxation rate on well width, as expected for the DP mechanism, but also considerable variation between samples from different sources, which we attribute to differences in sample interface morphology. (C) 1998 American Institute of Physics. [S0003-6951(98)02541-8].</p
High-velocity feature of the class I methanol maser in G309.38-0.13
The Australia Telescope Compact Array (ATCA) has been used to map class I
methanol masers at 36 and 44 GHz in G309.38-0.13. Maser spots are found at nine
locations in an area of 50''x30'', with both transitions reliably detected at
only two locations. The brightest spot is associated with shocked gas traced by
4.5 micron emission. The data allowed us to make a serendipitous discovery of a
high-velocity 36-GHz spectral feature, which is blue-shifted by about 30 km/s
from the peak velocity at this frequency, but spatially located close to
(within a few arcseconds of) the brightest maser spot. We interpret this as
indicating an outflow parallel to the line of sight. Such a high velocity
spread of maser features, which has not been previously reported in the class I
methanol masers associated with a single molecular cloud, suggests that the
outflow most likely interacts with a moving parcel of gas.Comment: 6 pages, 2 figures, accepted by MNRAS Letter
A preliminary design study of a microparticle accelerator final report, 30 jan. - 13 apr. 1964
Design study for 2MV microparticle accelerato
Experimentally-calibrated population of models predicts and explains inter-subject variability in cardiac cellular\ud electrophysiology
Cellular and ionic causes of variability in the electrophysiological activity of hearts from individuals of the same species are unknown. However, improved understanding of this variability is key to enable prediction of the response of specific hearts to disease and therapies. Limitations of current mathematical modeling and experimental techniques hamper our ability to provide insight into variability. Here we describe a methodology to unravel the ionic determinants of inter-subject variability exhibited in experimental recordings, based on the construction and calibration of populations of models. We illustrate the methodology through its application to rabbit Purkinje preparations, due to their importance in arrhythmias and safety pharmacology assessment. We consider a set of equations describing the biophysical processes underlying rabbit Purkinje electrophysiology and we construct a population of over 10,000 models by randomly assigning specific parameter values corresponding to ionic current conductances and kinetics. We calibrate the model population by closely comparing simulation output and experimental recordings at three pacing frequencies. We show that 213 of the 10,000 candidate models are fully consistent with the experimental dataset. Ionic properties in the 213 models cover a wide range of values, including differences up to ±100% in several conductances. Partial correlation analysis shows that particular combinations of ionic properties determine the precise shape, amplitude and rate dependence of specific action potentials. Finally, we demonstrate that the population of models calibrated using data obtained under physiological conditions quantitatively predicts the action potential duration prolongation caused by exposure to four concentrations of the potassium channel blocker dofetilide
Spatial synchronization and extinction of species under external forcing
We study the interplay between synchronization and extinction of a species.
Using a general model we show that under a common external forcing, the species
with a quadratic saturation term in the population dynamics first undergoes
spatial synchronization and then extinction, thereby avoiding the rescue
effect. This is because the saturation term reduces the synchronization time
scale but not the extinction time scale. The effect can be observed even when
the external forcing acts only on some locations provided there is a
synchronizing term in the dynamics. Absence of the quadratic saturation term
can help the species to avoid extinction.Comment: 4 pages, 2 figure
Study of a Large NaI(Tl) Crystal
Using a narrow band positron beam, the response of a large high-resolution
NaI(Tl) crystal to an incident positron beam was measured. It was found that
nuclear interactions cause the appearance of additional peaks in the low energy
tail of the deposited energy spectrum
In vitro starch disappearance procedure modifications
Four in vitro experiments evaluated the effects of ruminal fluid inoculum:artificial saliva ratios,
grinder type, grind size, and diet of ruminal fluid donor on in vitro starch disappearance. Experiment 1 examined rates of starch disappearance and coefficients of determination obtained by linear regression of starch disappearance using five grain sorghum (Sorghum bicolur (L.) Moench) lines, a corn (Zeu muys L.) control, and a wheat (Triticum aestivum L.) control. Grains were incubated for 4, 8, 12, 16, and 20 h with inoculum varying in proportion of ruminal fluid and artificial saliva ( l:l, 1:2, 1:3, and 1:4). In vitro rates of starch disappearance and coefficients of determination were similar for the 1:2, 1:3, and 1:4 inoculum dilutions and were higher (quadratic, P \u3c 0.01) than the 1:1 dilution. As the proportion of artificial saliva in the inoculum increased, in vitro pH increased (linear, P \u3c 0.01). In Experiment 2, six grain sorghum lines and a corn control were ground through a l-mm screen in a Udy (cyclone type) or Wiley mill. Starch disappearance for samples ground using a Udy mill were higher (P 0.10) by grain type fed; however, absolute rates of digestion varied among inoculate sources. Grinder, grind size, and ruminal fluid inoculum:artificial saliva ratios affected rate of starch disappearance in samples digested in vitro. Diet of ruminal fluid donor affected the rate of starch digestion, but not the relative ranking of the grains. If rates are to be compared across in vitro runs for different grains, these processing and dietary factors must be kept constant
High Purity Pion Beam at TRIUMF
An extension of the TRIUMF M13 low-energy pion channel designed to suppress
positrons based on an energy-loss technique is described. A source of beam
channel momentum calibration from the decay pi+ --> e+ nu is also described.Comment: 5 page
On a Conjecture of Goriely for the Speed of Fronts of the Reaction--Diffusion Equation
In a recent paper Goriely considers the one--dimensional scalar
reaction--diffusion equation with a polynomial reaction
term and conjectures the existence of a relation between a global
resonance of the hamiltonian system and the asymptotic
speed of propagation of fronts of the reaction diffusion equation. Based on
this conjecture an explicit expression for the speed of the front is given. We
give a counterexample to this conjecture and conclude that additional
restrictions should be placed on the reaction terms for which it may hold.Comment: 9 pages Revtex plus 4 postcript figure
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