3 research outputs found
Miradas acerca del SIMCE escritura: análisis de los procesos de aplicación y manejo de los resultados en establecimientos particulares subvencionados
- Publication venue
- Universidad Andres Bello
- Publication date
- 01/01/2018
- Field of study
Tesis (Magíster en Comprensión Lectora y Producción de Textos)El Simce escritura es una evaluación estandarizada realizada a los estudiantes de sexto año básico de todos los establecimientos educacionales de Chile. En ella se miden las habilidades de escritura que han logrado adquirir los niños durante su formación en educación básica. Posteriormente a la aplicación de la prueba, los directivos de cada establecimiento reciben los resultados obtenidos en la medición y algunos consejos para poder mejorar la enseñanza y aprendizaje de la escritura. El presente trabajo entrega un análisis de la visión de los directores, jefes de la Unidad Técnico-Pedagógica (UTP) y docente de la asignatura de Lenguaje y Comunicación acerca de la aplicación y manejo de resultados de la prueba Simce Escritura. Mediante un estudio cualitativo de caso se realizaron entrevistas semiestructuradas a tres directivos, jefes de UTP y docentes de tres colegios particulares subvencionados de las comunas de San Bernardo, Pedro Aguirre Cerda y Maipú. A partir de un análisis de los datos se presentan los resultados reunidos en cuatro ejes temáticos:1) percepciones relacionadas con la aplicación de la prueba Simce Escritura y cómo se preparan para ella; 2) Las percepciones acerca del uso de los resultados, que realizan los establecimientos y de las forma de comunicación a la comunidad educativa; 3) Consideraciones de los resultados de la prueba, para realizar cambios en sus planificaciones y formas de trabajo; 4) Valoraciones de los participantes acerca del Simce Escritura. Finalmente se concluye mencionando, las aportaciones y limitaciones del estudio, además de recomendaciones para generar nuevas investigaciones en el tema.Simce Escritura is a standardized assessment made to sixth grade students of all educational establishments in Chile. It measures the writing skills that children have managed to acquire during their basic education training. After the application of the test, the managers of each establishment receive the results obtained in the measurement and some tips to improve the teaching and learning of writing. The present work provides an analysis of the vision of the directors, heads of the Technical-Pedagogical Unit (UTP) and teacher of the subject of Language and Communication about the application and management of Simce Writing test results. Through a qualitative case study semi-structured interviews were conducted with three managers, UTP heads and teachers from three subsidized private schools in the districts of San Bernardo, Pedro Aguirre Cerda and Maipu.
Based on an analysis of the data, the results are presented in four thematic areas: 1) perceptions related to the application of the Simce Escritura test and how they prepare for it; 2) The perceptions about the use of the results, which the establishments make and the way of communication to the educational community; 3) Considerations of the results of the test, to make changes in their plans and forms of work; 4) Evaluations of the participants about Simce Escritura. Finally, it concludes by mentioning the contributions and limitations of the study, as well as recommendations to generate new research on the subject
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
- Author
- Abad Jorge
- Abel Laurent
- Abel Laurent
- Abel Laurent
- Abel Laurent
- Accordino Giulia
- Achille Cristian
- Acosta-Ampudia Yeny
- Agra Juan José Cáceres
- Aguilera-Albesa Sergio
- Aguiló-Cucurull Aina
- Aiuti Alessandro
- Aiuti Alessandro
- Aiuti Alessandro
- Akcan Özge Metin
- Al-Muhsen Saleh
- Al-Mulla Fahd
- Alavoine Loubna
- Albert Matthew
- Albisures Jonathan Antonio Roblero
- Alcover Andres
- Aldave Juan
- Algera Anne Geke
- Aliberti Anna
- Alkan Gulsum
- Alkhater Suzan
- Alkhater Suzan
- Allardet-Servent Jerome
- Allavena Clotilde
- Allende Luis
- Alonso-Arias Rebeca
- Alshahrani Mohammed
- Alsina Laia
- Alvarez Josep Trenado
- Alyanakian Marie-Alexandra
- Amador-Borrero Blanca
- Amat Karine
- Amoura Zahir
- Anaya Juan-Manuel
- Anderson Mark
- Anderson Mark
- Andreakos Evangelos
- Andreakos Evangelos
- Andrejak Claire
- Andrés Ana De
- Anglicheau Dany
- Angoulvant François
- Annereau Jean-Philippe
- Antolí Arnau
- Appelman Brent
- Arias Andrés
- Arias Andrés Augusto
- Arkin Lisa
- Arquero Miguel Fernandez
- Arranz María Jesús
- Arrestier Romain
- Arrestier Romain
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- Aschard Hugues
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- Auguet Teresa
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- Aytekin Selma Erol
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- Bahram Seiamak
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- Rieux-Laucat Frédéric
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- Rigo-Bonnin Raúl
- Rivet Nadia
- Rivière Jacques
- Rivière Jacques
- Rocamora-Blanch Gemma
- Rodero Mathieu
- Rodrigo Carlos
- Rodriguez Luis Antonio
- Rodriguez-Gallego Carlos
- Rodriguez-Palmero Agustí
- Rodríguez Yhojan
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- Rodríguez-Gallego Carlos
- Rogge Lars
- Rojas Manuel
- Rojas-Villaraga Adriana
- Romero Carolina Soledad
- Rosa-Calatrava Manuel
- Rosain Jérémie
- Rosen Lindsey
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- Rossignol Patrick
- Rothenbuhler Anya
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- Rowen Lee
- Roy Carine
- Rozenberg Flore
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- Ruiz-Rodriguez Juan Carlos
- Sabater-Riera Joan
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- Saks Kai
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- Sediva Anna
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- Sene Damien
- Seng Piseth
- Senoglu Sevtap
- Seppänen Mikko
- Seppänen Mikko R.J.
- Shahrooei Mohammad
- Shahrooei Mohammed
- Sharif-Askari Fatemeh Saheb
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- Shcherbina Anna
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- Su Helen
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- Sørensen Erik
- Taccone Fabio
- Talouarn Estelle
- Tanaka Junko
- Tancevski Ivan
- Tancevski Ivan
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- Tandjaoui-Lambiotte Yacine
- Tangy Frédéric
- Tangye Stuart
- Tangye Stuart
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- Taupin Jean-Luc
- Tavernier Simon
- Tayoun Ahmad Abou
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- Terrier Benjamin
- Terrier Olivier
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- Tiberghien Pierre
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- Tolstrup Martin
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- Trouillet-Assant Sophie
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- Troya Jesús
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- Tsonas Anissa
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- Tubiana Sarah
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- Tzourio Christophe
- Téoulé François
- Uddin K.
- Uddin Mohammed
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- Ursini Matilde Valeria
- Utsumi Takanori
- Uzunhan Yurdagul
- Vabres Pierre
- Valencia-Ramos Juan
- Valsecchi Maria Grazia
- van Agtmael Michiel
- van Baarle Frank
- van Braeckel Eva
- van de Beek Diederik
- van de Beek Diederik
- van de Beek Diederik
- van den Rym Ana Maria
- van der Poll Tom
- van der Valk Marc
- van der Werf Sylvie
- van der Werf Sylvie
- van Mourik Niels
- van Praet Jens
- van Vugt Michèle
- Vanderlinden Dimitri
- Vandernoot Isabelle
- Vanel Noémie
- Vasse Marc
- Veelo Denise
- Veislinger Aurélie
- Velez-Santamaria Valentina
- Veliz Silvia Patricia Zuniga
- Venet Fabienne
- Vergara José Alejandro Daza
- Vidaur Loreto
- Vidaur Loreto
- Vidigal Mateus
- Vidigal Mateus
- Viel Sébastien
- Vignali Valérie
- Vilaire-Meunier Marie
- Villain Cédric
- Villar-García Judit
- Vincent Audrey
- Vinh Donald
- Vinh Donald
- Visseaux Benoit
- Visseaux Benoit
- Vlaar Alexander
- Vogt Guillaume
- Voiriot Guillaume
- Volleman Carolien
- Volokha Alla
- von Bernuth Horst
- von Stemann Jakob Hjorth
- Vught Lonneke
- Vuotto Fanny
- Vélez Verónica Posada
- Waucquier Nawal
- Wauters Els
- Wauters Joost
- Wauters Joost
- Wauters Joost
- Wiedemann Aurélie
- Wiersinga W. Joost
- Wouters Dorien
- Wu Alan
- Wu Tak-Chiu
- Yahşi Aysun
- Yang Rui
- Yasar Kadriye Kart
- Yazdanpanah Yazdan
- Yazdanpanah Yazdan
- Yepes Jairo David Torres
- Yesilbas Osman
- Yildiz Mehmet
- Young Barnaby
- Yükselmiş Ufuk
- Zatz Mayana
- Zatz Mayana
- Zatz Mayana
- Zawadzki Pawel
- Zhang Peng
- Zhang Qian
- Zhang Shen-Ying
- Zhang Yu
- Zimmer Christophe
- Zins Marie
- Zins Marie
- Zuccaro Valentina
- Zwinderman A.
- Íñigo-Campos Antonio
- Öz Şadiye Kübra Tüter
- Özkan Esra Akyüz
- Özçelik Tayfun
- Publication venue
- 'Proceedings of the National Academy of Sciences'
- Publication date
- 24/05/2022
- Field of study
International audienceSignificance There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. Using an unvaccinated sample of 1,261 deceased patients and 34,159 individuals from the general population, we found that autoantibodies against type I IFNs strongly increased the SARS-CoV-2 infection fatality rate at all ages, in both men and women. Autoantibodies against type I IFNs are strong and common predictors of life-threatening COVID-19. Testing for these autoantibodies should be considered in the general population
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
- Author
- Abad Jorge
- Abel Laurent
- Abel Laurent
- Abel Laurent
- Abel Laurent
- Accordino Giulia
- Achille Cristian
- Acosta-Ampudia Yeny
- Agra Juan José Cáceres
- Aguilera-Albesa Sergio
- Aguiló-Cucurull Aina
- Aiuti Alessandro
- Aiuti Alessandro
- Aiuti Alessandro
- Akcan Özge Metin
- Al-Muhsen Saleh
- Al-Mulla Fahd
- Alavoine Loubna
- Albert Matthew
- Albisures Jonathan Antonio Roblero
- Alcover Andres
- Aldave Juan
- Algera Anne Geke
- Aliberti Anna
- Alkan Gulsum
- Alkhater Suzan
- Alkhater Suzan
- Allardet-Servent Jerome
- Allavena Clotilde
- Allende Luis
- Alonso-Arias Rebeca
- Alshahrani Mohammed
- Alsina Laia
- Alvarez Josep Trenado
- Alyanakian Marie-Alexandra
- Amador-Borrero Blanca
- Amat Karine
- Amoura Zahir
- Anaya Juan-Manuel
- Anderson Mark
- Anderson Mark
- Andreakos Evangelos
- Andreakos Evangelos
- Andrejak Claire
- Andrés Ana De
- Anglicheau Dany
- Angoulvant François
- Annereau Jean-Philippe
- Antolí Arnau
- Appelman Brent
- Arias Andrés
- Arias Andrés Augusto
- Arkin Lisa
- Arquero Miguel Fernandez
- Arranz María Jesús
- Arrestier Romain
- Arrestier Romain
- Asano Takaki
- Aschard Hugues
- Aubart Mélodie
- Auguet Teresa
- Avramenko Iryna
- Aytekin Gökhan
- Aytekin Selma Erol
- Azot Axelle
- Azoulay Cecile
- Bachelet Delphine
- Bahram Seiamak
- Bajolle Fanny
- Baldanti Fausto
- Baldolli Aurélie
- Ballester Maite
- Baris-Feldman Hagit
- Barreiros Lucila
- Barrou Benoit
- Bartoli Marie
- Barzaghi Federica
- Basmaci Romain
- Basso Sabrina
- Bastard Paul
- Batten Isabella
- Bauters Fré
- Bax Diane
- Bayhan Gulsum Iclal
- Behillil Sylvie
- Behillill Sylvie
- Bellani Giacomo
- Belot Alexandre
- Belot Alexandre
- Belot Alexandre
- Beluze Marine
- Benech Nicolas
- Benkerrou Dehbia
- Beretta Ilaria
- Bergin Colm
- Bertholon Frédérique
- Bettini Laura Rachele
- Beudel Martijn
- Bezrodnik Liliana
- Bhavsar Krishna
- Biggs Catherine
- Biggs Catherine
- Bilbao Agurtzane
- Bilguvar Kaya
- Biondi Andrea
- Bitker Laurent
- Bizien Lucy
- Blanchard-Rohner Geraldine
- Blanco Ignacio
- Blandinières Adeline
- Bleibtreu Alexandre
- Bloomfield Marketa
- Blázquez-Gamero Daniel
- Bogaard Harm Jan
- Bogunovic Dusan
- Boisson Bertrand
- Bolivar-Prados Mireia
- Bolze Alexandre
- Bomers Marije
- Bondarenko Anastasiia
- Bondarenko Anastasiia
- Bondarenko Anastasiia
- Bonfanti Paolo
- Bonneaudeau Brigitte
- Bonta Peter
- Borghesi Alessandro
- Borie Raphael
- Borrero Blanca Amador
- Bos Lieuwe
- Bosteels Cédric
- Botdhlo-Nevers Elisabeth
- Botelho-Nevers Elisabeth
- Botta Michela
- Bouadma Lila
- Bouadma Lila
- Boucherit Soraya
- Boudhabhay Idris
- Bouiller Kévin
- Boulanger Cécile
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- Bourgeon Marilou
- Bourke Nollaig
- Bourke Nollaig
- Bourke Nollaig
- Bouscambert-Duchamp Maude
- Bousfiha Ahmed
- Bousfiha Ahmed
- Bousfiha Ahmed
- Bousquet Aurore
- Bousso Philippe
- Boutolleau David
- Bouvattier Claire
- Boyarchuk Oksana
- Boyarchuk Oksana
- Bozdemir Şefika Elmas
- Bravais Juliette
- Briones M. Luisa
- Briseño-Roa Luis
- Brodin Petter
- Brodin Petter
- Brouwer Matthijs
- Bruhns Pierre
- Bruneau Léa
- Brunner Marie-Eve
- Bruno Raffaele
- Bryceson Yenan
- Bueno Maria Rita P.
- Bugiani Marianna
- Buis David
- Bukhari Huda
- Bulle Esther
- Burdet Charles
- Burdet Charles
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- Bustamante Jacinta
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- Ceschi Alessandro
- Chahine Abir
- Chair Anissa
- Chakravorty Samya
- Chalumeau Martin
- Charbit Bruno
- Charpentier Charlotte
- Chauvineau-Grenier Angélique
- Chen Jie
- Cheng Matthew
- Chirouze Catherine
- Chirouze Catherine
- Chouchane Osoul
- Chrabieh Maya
- Christodoulou John
- Ciceri Fabio
- Citerio Giuseppe
- Clavé Pere
- Clercq Jozefien De
- Cloherty Alex
- Clotet Bonaventura
- Cobat Aurélie
- Codina Anna
- Coelho Alexandra
- Coeuret-Pellicer Mireille
- Cognasse Fabrice
- Cognasse Fabrice
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- Colobran Roger
- Colobran Roger
- Comarmond Cloé
- Combes Alain
- Comoli Patrizia
- Condino-Neto Antonio
- Condino-Neto Antonio
- Conlon Niall
- Connolly Emma
- Constantinescu Stefan
- Conti Francesca
- Contro Ernesto
- Cooper Megan
- Cordel Hugues
- Correales Luisa Paola Duarte
- Corsico Angelo
- Couffignal Camille
- Couffin-Cadiergues Sandrine
- Couffin-Cadiergues Sandrine
- Coulongeat Matthieu
- Coşkuner Taner
- Cruz Inés Marín
- Cuadros Esmeralda Nuñez
- Cumano Ana
- Cvetkovski Aleksandar
- Cyrus Cyril
- Daganou Maria
- Dalgard Clifton
- Dalgard Clifton
- Dalmau David
- Dalmau David
- Danielson Jeffrey
- Danion François
- Darazam Ilad Alavi
- Darley David Ross
- Das Vincent
- Dauby Nicolas
- Dauger Stéphane
- de Brabander Justin
- de Bree Godelieve
- de Bruin Sanne
- de Chambrun Marc Pineton
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- de Jong Menno
- de la Chapelle Aliénor
- de Lamballerie Xavier
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- Debette Stéphanie
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- Demirkol Yasemin Kendir
- Demoule Alexandre
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- Deplanque Dominique
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- Descamps Diane
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- Desille-Dugast Mireille
- Desmarets Maxime
- Desvallée Mathilde
- Di Sabatino Antonio
- Di Santo James
- Diallo Alpha
- Diego Rebeca Pérez De
- Diehl Jean-Luc
- Diehl Jean-Luc
- Dijkstra Mirjam
- Dillies Marie-Agnès
- Ding Li
- Dinh Khoa Manh
- Diouf Alphonsine
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- Dobbelaere Stephanie
- Dobbs Kerry
- Dominguez-Garrido Elena
- Domínguez-Garrido Elena
- Dongelmans Dave
- Dorgham Karim
- Dorival Céline
- Drolet Beth
- Dromer Françoise
- Dubos François
- Dubost Clément
- Duffy Darragh
- Duffy Darragh
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- Dujardin Romein
- Dunne Jean
- Dupont Annabelle
- Duval Xavier
- Duval Xavier
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- Dyer Adam
- D’angio Mariella
- D’enfert Christophe
- D’ortenzio Eric
- Eberl Gérard
- Ecobichon Jean-Luc
- Ekwall Olov
- El Baghdadi Jamila
- El Bakkouri Jalila
- Elbers Paul
- Elnagdy Marwa
- Eloy Philippine
- Emiroglu Melike
- Endo Akifumi
- Enninga Jost
- Enouf Vincent
- Enouf Vincent
- Epaulard Olivier
- Erdeniz Emine Hafize
- Erikstrup Christian
- Erikstrup Christian
- Esperou Hélène
- Espinosa-Padilla Sara
- Esposito-Farase Marina
- Espérou Hélène
- Etienne Manuel
- Eto Shohei
- Euvrard Romain
- Fabio Giovanna
- Faivre Laurence
- Falck Antonin
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- Fartoukh Muriel
- Faure Morgane
- Fekkar Arnaud
- Feldman Hagit Baris
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- Fellay Jacques
- Fellay Jacques
- Fellay Jacques
- Ferrer Ricard
- Ferreres Jose
- Fievet Nathalie
- Flaig Amandine
- Fleuren Lucas
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- Flores Carlos
- Florkin Benoit
- Fontes Magnus
- Foti Giuseppe
- Fouchard Julie
- Franco José Luis
- Franco José Luis
- Francois Bruno
- Frezouls Wahiba
- Froidure Antoine
- Fumadó Victoria
- Fung Kitty
- Fusco Francesca
- Gagneux-Brunon Amandine
- Gagro Alenka
- Gallian Pierre
- Garcia-Prat Marina
- García Paula Andrea Gaviria
- Garot Denis
- Garçon Pierre
- Gatineau Audrey Giraud
- Gaudet Alexandre
- Gault Nathalie
- Gaussem Pascale
- Gaymard Alexandre
- Gayretli Zeynep
- Geerlings Suzanne
- Geijtenbeek Theo
- Gentile Stéphanie
- Gervais Adrian
- Ghirardello Stefano
- Ghosn Jade
- Gigante Tristan
- Gil-Herrera Juana
- Gilardin Laurent
- Gilardin Laurent
- Gilg Morgane
- Girbes Armand
- Girona-Alarcón Mònica
- Gissot Valérie
- Godínez Karen Alejandra Cifuentes
- Goehringer François
- Goffard Jean-Christophe
- Goldberg Marcel
- Gomperts-Boneca Ivo
- Gonzales Nacho
- Gonzalez-Granado Luis
- González-Montelongo Rafaela
- Goorhuis Bram
- Gorochov Guy
- Got Stéphane Le
- Gregersen Peter
- Gregersen Peter
- Gribouval Olivier
- Grimbacher Bodo
- Grobusch Martin
- Guaqueta Jeser Santiago Grass
- Guedj Jérémie
- Guerder Antoine
- Gumucio Victor Daniel
- Gunst Jan
- Gut Marta
- Gálvez-Romero José Luis
- Gérardin Patrick
- Gómez Oscar
- Gülhan Belgin
- Hadjadj Jérôme
- Haerynck Filomeen
- Haerynck Filomeen
- Haerynck Filomeen
- Hafkamp Florianne
- Hagens Laura
- Hagin David
- Hagin David
- Haljasmägi Liis
- Halwani Rabih
- Halwani Rabih
- Halwani Rabih
- Hamann Jorg
- Hammarström Lennart
- Hammarström Lennart
- Hammarström Lennart
- Hamzeh-Cognasse Hind
- Hancerli Selda
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- Heath James
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- Meyts Isabelle
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- Mezidi Mehdi
- Michailidis Eleftherios
- Michel Frédérique
- Migaud Maria-Claire
- Migaud Mélanie
- Migeotte Isabelle
- Mikkelsen Susan
- Millereux Maude
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- Milner Joshua
- Mirault Tristan
- Mircher Clotilde
- Mironska Kristina
- Mirsaeidi Mehdi
- Mizoguchi Yoko
- Modi Bhavi
- Mogensen Trine
- Mogensen Trine
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- Moncomble Elsa
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- Monsalve Diana
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- Montagne Samatha
- Morandeira Francisco
- Morandeira Francisco
- Morange Pierre-Emmanuel
- Mordacq Clémence
- Morel Pascal
- Morel Pascal
- Morelle Guillaume
- Morio Tomohiro
- Morio Tomohiro
- Mouly Stéphane
- Mouquet Hugo
- Mouquet Hugo
- Mullaert Jimmy
- Muñoz-Barrera Adrián
- Mège Jean-Louis
- Mégarbane Bruno
- Ménager Mickaël
- Nadif Rachel
- Nadji Seyed Alireza
- Naesens Leslie
- Nafati Cyril
- Nagashima Shintaro
- Nakagama Yu
- Navarro Laura Mancera
- Neant Nadège
- Nellen Jeaninne
- Nemirowskaya Yelena
- Neven Bénédicte
- Neves João Farela
- Ng Lisa
- Ng Lisa
- Ng Yuk-Yung
- Nguyen Duc
- Nguyen Duc
- Ni Cheallaigh Cliona
- Nielly Hubert
- Noonan Claire
- Noret Marion
- Nossent Esther
- Notarangelo Luigi
- Notarangelo Luigi
- Nouroudine Mariama
- Novelli Antonio
- Novelli Giuseppe
- Nukui Yoko
- Nussenzweig Michel
- Ocejo-Vinyals J. Gonzalo
- Okada Satoshi
- Okada Satoshi
- Okamoto Keisuke
- Okamoto Keisuke
- Oriol Roger Colobran
- Ostrowski Sisse Rye
- Oualha Mehdi
- Ouedrani Amani
- Ozcelik Tayfun
- Ozcelik Tayfun
- Ozguler Anna
- Ozkaya-Parlakay Aslinur
- O’farrelly Cliona
- O’farrelly Cliona
- O’farrelly Cliona
- Pagani Michele
- Pan-Hammarström Qiang
- Pan-Hammarström Qiang
- Pan-Hammarström Qiang
- Papadaki Maria
- Papadopoulos Aurélie
- Pape Jean
- Paris Christophe
- Parizot Christophe
- Parola Philippe
- Parra-Martínez Alba
- Pascreau Tiffany
- Patin Etienne
- Paul Christelle
- Paul Stéphane
- Paul Stéphane
- Paulsen Isabella Worlewenut
- Paulus Frederique
- Payet Christine
- Paz Pauline Caraux
- Paz-Artal Estela
- Pedersen Ole Birger
- Pedraza-Sánchez Sigifredo
- Peiffer-Smadja Nathan
- Peigne Vincent
- Pelet Anna
- Pelet Sophie
- Pellecer Nancy Carolina González
- Pellegrini Sandra
- Pellegrini Silvia
- Pereira Jesus Marquez
- Perez-Tur Jordi
- Perlin David
- Perreau Pauline
- Perroquin Magali
- Pesci Alberto
- Pesole Graziano
- Pession Andrea
- Peters Edgar
- Peterson Pärt
- Petrov-Sanchez Ventzislava
- Peytavin Gilles
- Pham Huong
- Philippe Aurélien
- Philippot Quentin
- Philippot Quentin
- Picod Adrien
- Picone Olivier
- Piemonti Lorenzo
- Pina-Fuentes Dan
- Piquard Valentine
- Piquard Valentine
- Piralla Antonio
- Pistone Thierry
- Planas Anna
- Planas Anna
- Planas-Serra Laura
- Ploin Dominique
- Poissy Julien
- Poissy Julien
- Poissy Julien
- Poncelet Géraldine
- Poulakou Garyphallia
- Pouletty Marie
- Pourshahnazari Persia
- Prado Maria Yolanda Ruiz Del
- Prando Carolina
- Prando Carolina
- Preckel Bennedikt
- Prins Jan
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- Pueyo David Martínez
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- Pujol Aurora
- Puéchal Oriane
- Pérez Cristian Alejandro Ricaurte
- Pérez-Díaz Carlos
- Pérez-Fernández Xosé Luis
- Qiu-Chen Jia Li
- Quaresima Virginia
- Quentric Paul
- Quintana-Murci Lluis
- Quintana-Murci Lluis
- Quintana-Murci Lluis
- Quintin Caroline
- Quiros-Roldan Eugenia
- Raasveld Jorinde
- Ramaswamy Sathishkumar
- Rambaud Thomas
- Ramirez-Santana Carolina
- Ramos Miquel Alfonso
- Raoult Didier
- Raoult Didier
- Raoult Violette
- Rapti Vasiliki
- Rausell Antonio
- Rebillat Anne-Sophie
- Reddy Conor
- Redin Claire
- Reijnders Tom
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- Resnick Igor
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- Ricaurte Oscar Andrés Briceño
- Rice Charles
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- Richard Lucie
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- Richard Pascale
- Rieux-Laucat Frédéric
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- Rigo-Bonnin Raúl
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- Rivière Jacques
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- Rodríguez-Gallego Carlos
- Rodríguez-Gallego Carlos
- Rogge Lars
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- Rosa-Calatrava Manuel
- Rosain Jérémie
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- Rossi Camillo
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- Rossignol Patrick
- Rothenbuhler Anya
- Roufai Layidé
- Roussel Lucie
- Roux Damien
- Rovina Nikoletta
- Rowen Lee
- Roy Carine
- Rozenberg Flore
- Ruch Yvon
- Ruiz Montse
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- Sabater-Riera Joan
- Sahanic Sabina
- Saker Kahina
- Saks Kai
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- Sallette Jérôme
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- Senoglu Sevtap
- Seppänen Mikko
- Seppänen Mikko R.J.
- Shahrooei Mohammad
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- Sharif-Askari Fatemeh Saheb
- Shaw Elana
- Shcherbina Anna
- Shcherbina Anna
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- Shorte Spencer
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- Sobh Ali
- Solanich Xavier
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- Soler-Palacin Pere
- Soler-Palacín Pere
- Soler-Palacín Pere
- Solis Blanca Garcia
- Solé-Violán Jordi
- Solé-Violán Jordi
- Sottini Alessandra
- Soumaré Aïcha
- Spaan András
- Spaan András
- Stella Giulia Maria
- Stepanian Alain
- Stepanovskiy Yuriy
- Stepanovskyy Yurii
- Stijnis Cornelis
- Stilma Willemke
- Stoclin Annabelle
- Storgaard Merete
- Su Helen
- Su Helen
- Su Richa
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- Syrigos Konstantinos
- Sánchez-Montalvá Adrián
- Sánchez-Ramón Silvia
- Särekannu Karita
- Sözeri Betül
- Sørensen Erik
- Taccone Fabio
- Talouarn Estelle
- Tanaka Junko
- Tancevski Ivan
- Tancevski Ivan
- Tandjaoui-Lambiotte Yacine
- Tandjaoui-Lambiotte Yacine
- Tangy Frédéric
- Tangye Stuart
- Tangye Stuart
- Tardivon Coralie
- Tardy Bernard
- Taupin Jean-Luc
- Tavernier Simon
- Tayoun Ahmad Abou
- Tellier Marie-Capucine
- Terrier Benjamin
- Terrier Olivier
- Teunissen Charlotte
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- Thibault Chloé
- Thiery Guillaume
- Thoral Patrick
- Thorball Christian
- Thorn Karolina
- Thumerelle Caroline
- Thy Michael
- Tiberghien Pierre
- Tiberghien Pierre
- Timsit Jean-François
- Tipu Imran
- Tolstrup Martin
- Tolstrup Martin
- Tomasoni Gabriele
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- Toubiana Julie
- Touvier Mathilde
- Townsend Liam
- Triantafyllia Vasiliki
- Trouillet-Assant Sophie
- Trouillet-Assant Sophie
- Troya Jesús
- Troya Jesús
- Tsang Owen
- Tserel Liina
- Tso Eugene
- Tsonas Anissa
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- Tual Christelle
- Tubiana Sarah
- Tubiana Sarah
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- Tuinman Pieter
- Turvey Stuart
- Tzourio Christophe
- Téoulé François
- Uddin K.
- Uddin Mohammed
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- Ursini Matilde Valeria
- Utsumi Takanori
- Uzunhan Yurdagul
- Vabres Pierre
- Valencia-Ramos Juan
- Valsecchi Maria Grazia
- van Agtmael Michiel
- van Baarle Frank
- van Braeckel Eva
- van de Beek Diederik
- van de Beek Diederik
- van de Beek Diederik
- van den Rym Ana Maria
- van der Poll Tom
- van der Valk Marc
- van der Werf Sylvie
- van der Werf Sylvie
- van Mourik Niels
- van Praet Jens
- van Vugt Michèle
- Vanderlinden Dimitri
- Vandernoot Isabelle
- Vanel Noémie
- Vasse Marc
- Veelo Denise
- Veislinger Aurélie
- Velez-Santamaria Valentina
- Veliz Silvia Patricia Zuniga
- Venet Fabienne
- Vergara José Alejandro Daza
- Vidaur Loreto
- Vidaur Loreto
- Vidigal Mateus
- Vidigal Mateus
- Viel Sébastien
- Vignali Valérie
- Vilaire-Meunier Marie
- Villain Cédric
- Villar-García Judit
- Vincent Audrey
- Vinh Donald
- Vinh Donald
- Visseaux Benoit
- Visseaux Benoit
- Vlaar Alexander
- Vogt Guillaume
- Voiriot Guillaume
- Volleman Carolien
- Volokha Alla
- von Bernuth Horst
- von Stemann Jakob Hjorth
- Vught Lonneke
- Vuotto Fanny
- Vélez Verónica Posada
- Waucquier Nawal
- Wauters Els
- Wauters Joost
- Wauters Joost
- Wauters Joost
- Wiedemann Aurélie
- Wiersinga W. Joost
- Wouters Dorien
- Wu Alan
- Wu Tak-Chiu
- Yahşi Aysun
- Yang Rui
- Yasar Kadriye Kart
- Yazdanpanah Yazdan
- Yazdanpanah Yazdan
- Yepes Jairo David Torres
- Yesilbas Osman
- Yildiz Mehmet
- Young Barnaby
- Yükselmiş Ufuk
- Zatz Mayana
- Zatz Mayana
- Zatz Mayana
- Zawadzki Pawel
- Zhang Peng
- Zhang Qian
- Zhang Shen-Ying
- Zhang Yu
- Zimmer Christophe
- Zins Marie
- Zins Marie
- Zuccaro Valentina
- Zwinderman A.
- Íñigo-Campos Antonio
- Öz Şadiye Kübra Tüter
- Özkan Esra Akyüz
- Özçelik Tayfun
- Publication venue
- 'Proceedings of the National Academy of Sciences'
- Publication date
- 24/05/2022
- Field of study
International audienceSignificance There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. Using an unvaccinated sample of 1,261 deceased patients and 34,159 individuals from the general population, we found that autoantibodies against type I IFNs strongly increased the SARS-CoV-2 infection fatality rate at all ages, in both men and women. Autoantibodies against type I IFNs are strong and common predictors of life-threatening COVID-19. Testing for these autoantibodies should be considered in the general population