An Investigation into the Geometry of Seyfert Galaxies

We present a new method for the statistical investigation into the distributions of the angle beta between the radio axis and the normal to the galactic disk for a sample of Seyfert galaxies. We discuss how further observations of the sample galaxies can strengthen the conclusions. Our data are consistent with the hypothesis that AGN jets are oriented randomly in space, independent of the position of the plane of the galaxy. By making the simple assumption that the Standard Model of AGN holds, with a universal opening angle of the thick torus of phi_c, we demonstrate a statistical method to obtain an estimate of phi_c. Our data are not consistent with the simple-minded idea that Seyfert 1s and Seyfert 2s are differentiated solely by whether or not our line of sight lies within some fixed angle of the jet axis. Our result is significant on the 2 sigma level and can thus be considered only suggestive, not conclusive. A complete sample of Seyfert galaxies selected on an isotropic property is required to obtain a conclusive result.Comment: 13 pages, Tex, 5 Postscript figures. Accepted Ap

Treatment options for pediatric patent ductus arteriosus: Systematic review and meta-analysis

BACKGROUND: Patent ductus arteriosus (PDA) in the nonpremature pediatric patient is currently treated by surgical ligation or catheter occlusion. There is no clear superiority of one technique over the other. This meta-analysis compares the clinical outcomes of the two treatment options for PDA. METHODS: We performed a literature search of MEDLINE, Embase, PubMed, and the Cochrane database of randomized controlled trials (RCTs) that took place between 1950 and February 2014 and hand-searched references from included studies. We excluded studies of adult or premature patients and those without a direct comparison between surgical and catheter-based treatments of PDAs. Outcomes of interest were reintervention, total complications, length of stay, and cost. RESULTS: One thousand three hundred thirty-three manuscripts were screened. Eight studies fulfilled the inclusion criteria (one RCT and seven observational studies [N = 1,107]). In pooled observational studies, there were significantly decreased odds (OR, 0.12; 95% CI, 0.03-0.42) for reintervention in the surgical ligation group but insignificantly higher odds for overall complications (OR, 2.01; 95% CI, 0.68-5.91). There were no complications reported in the RCT, but surgical ligation was associated with decreased odds for reintervention and a longer length of stay. Funnel plots revealed a possible publication bias and a quality review identified comparability bias. CONCLUSIONS: Both therapies have comparable outcomes. Reintervention is more common with catheter-based treatment, but overall complication rates are not higher and hospital stay is shorter. Our data span \u3e 2 decades and may not reflect current surgical and catheterization outcomes. Large, randomized, prospective studies may help determine the optimal treatment strategy

Is it Round? Spectropolarimetry of the Type II-P Supernova 1999em

We present the first multi-epoch spectropolarimetry of a type II plateau supernova (SN II-P), with optical observations of SN 1999em on days 7, 40, 49, 159, and 163 after discovery. These data are used to probe the geometry of the electron-scattering atmosphere before, during, and after the plateau phase, which ended roughly 90 days after discovery. Weak continuum polarization with an unchanging polarization angle (theta ~ 160 deg) is detected at all epochs, with p ~ 0.2% on day 7, p ~ 0.3% on days 40 and 49, and p ~ 0.5% in the final observations. Distinct polarization modulations across strong line features are present on days 40, 49, 159, and 163. Uncorrected for interstellar polarization (which is believed to be quite small), polarization peaks are associated with strong P Cygni absorption troughs and nearly complete depolarization is seen across the H-alpha emission profile. The temporal evolution of the continuum polarization and sharp changes across lines indicate polarization intrinsic to SN 1999em. When modeled in terms of the oblate, electron-scattering atmospheres of Hoeflich, the observed polarization implies anasphericity of at least 7% during the period studied. The temporal polarization increase may indicate greater asphericity deeper into the ejecta. We discuss the implications of asphericity on the use of type II-P supernovae as primary extragalactic distance indicators through the expanding photosphere method (EPM). If asphericity produces directionally dependant flux and peculiar galaxy motions are characterized by sigma_v_rec = 300 km/s, it is shown that the agreement between previous EPM measurements of SNe II and distances to the host galaxies predicted by a linear Hubble law restrict mean SN II asphericity to values less than 30% (3-sigma) during the photospheric phase.Comment: 65 pages (29 Figures, 4 Tables), Accepted for publication in the June 1, 2001 edition of ApJ. Revised statistical analysis of scatter in Hubble diagram of previous EPM distances and the implications for mean SN II asphericit

Multiband optical polarimetry of the BL Lac object PKS 2155--304. Intranight and long term variability

The polarized and total flux of the BL Lac object PKS 2155-304 were monitored intensively and simultaneously in the optical UBVRI bands with the Turin photopolarimeter at the CASLEO 2.15 m telescope during 4 campaigns in June, August, November 1998 and August 1999. The effective observation time amounted to ~47 hours. PKS 2155-304 showed a linear polarization percentage (P) usually ranging between 3% and 7% and a polarization position angle (PA) mainly between 70 and 120 deg. The highest temporal resolution of our observations, 15 minutes, is unprecedented for polarimetric monitoring of this source, and has allowed us to detect amplitude variations of the linear polarization percentage from 6 to 7.5% in time scales of hours. In some nights the polarization percentage seems to increase toward shorter wavelengths, however the polarized spectrum does not vary significantly with time. The most remarkable variability event occurred on 1998 June 18, when the degree of linear polarization decreased by more than a factor 2 in one day in all bands, while the PA rotated by 90 deg. This is consistent with the presence of two emission components, of different polarization degree and position angle. Intranight variability of P and PA can be interpreted with small amplitude physical or geometrical changes within the jet. Measurements of the circular polarization over time intervals of days set upper limits of 0.2%. Simultaneous photometry taken with the Turin Photopolarimeter and with a CCD camera at Cordoba Astronomical Observatory did not show light variations correlated with those of the linearly polarized flux.Comment: 21 pages, 6 eps figures. Accepted for The Astrophysical Journal Supplement Serie

Jet directions in Seyfert galaxies: Radio continuum imaging data

We present the results of VLA A-array 8.46 GHz continuum imaging of 55 Seyfert galaxies (19 Seyfert 1's and 36 Seyfert 2's). These galaxies are part of a larger sample of 88 Seyfert galaxies, selected from mostly isotropic properties, the flux at 60 mum and warm infrared 25 mum to 60 mum colors. These images are used to study the structure of the radio continuum emission of these galaxies and their position angles, in the case of extended sources. These data, combined with information from broad-band B and I observations, have been used to study the orientation of radio jets relative to the plane of their host galaxies (Kinney et al. 2000).Comment: To appear in The Astrophysical Journal Supplement Series, February 2001, 14 pages, 1 figure (6 pages), 2 table

Identifying active vascular microcalcification by (18)F-sodium fluoride positron emission tomography.

Vascular calcification is a complex biological process that is a hallmark of atherosclerosis. While macrocalcification confers plaque stability, microcalcification is a key feature of high-risk atheroma and is associated with increased morbidity and mortality. Positron emission tomography and X-ray computed tomography (PET/CT) imaging of atherosclerosis using (18)F-sodium fluoride ((18)F-NaF) has the potential to identify pathologically high-risk nascent microcalcification. However, the precise molecular mechanism of (18)F-NaF vascular uptake is still unknown. Here we use electron microscopy, autoradiography, histology and preclinical and clinical PET/CT to analyse (18)F-NaF binding. We show that (18)F-NaF adsorbs to calcified deposits within plaque with high affinity and is selective and specific. (18)F-NaF PET/CT imaging can distinguish between areas of macro- and microcalcification. This is the only currently available clinical imaging platform that can non-invasively detect microcalcification in active unstable atherosclerosis. The use of (18)F-NaF may foster new approaches to developing treatments for vascular calcification.AI Wellcome Trust PhD Programme in Metabolic and Cardiovascular Disease Grant Number 096823/Z/11/Z, Wellcome Trust (WT103782AIA), British Heart Foundation (RG/10/007/28300, CH/09/002/26360, PG/12/8/29371), NHS Research Scotland and NIHR Cambridge Biomedical Research Centre.This is the final version of the article. It first appeared from the Nature Publishing Group via http://dx.doi.org/10.1038/ncomms849

Cosmological Constraints on Lorentz Violation in Electrodynamics

Infrared, optical, and ultraviolet spectropolarimetry of cosmological sources is used to constrain the pure electromagnetic sector of a general Lorentz-violating standard-model extension. The coefficients for Lorentz violation are bounded to less than 3x10^{-32}.Comment: 4 pages, accepted for publication in Physical Review Letter