Gross Anatomy for Physical Therapy course

The study of anatomy supported with human dissection is foundational to training of health science professionals. For a student, cadaver dissection offers an active learning experience. For the training of physical therapists, we created a manual that efficiently instructs the dissection of the whole body over the course of 30 laboratory periods. In the spirit of academic collegiality, this letter provides health science educators a direct download link (https://hdl.handle.net/11299/218174) to the dissection manual hosted by the University of Minnesota (USA) Digital Conservancy. No registration is required, the download is free, and the PDF file of the dissection manual can be reproduced or adapted for any educational use. &nbsp

A Distribution of Large Particles in the Coma of Comet 103P/Hartley 2

The coma of comet 103P/Hartley 2 has a significant population of large particles observed as point sources in images taken by the Deep Impact spacecraft. We measure their spatial and flux distributions, and attempt to constrain their composition. The flux distribution of these particles implies a very steep size distribution with power-law slopes ranging from -6.6 to -4.7. The radii of the particles extend up to 20 cm, and perhaps up to 2 m, but their exact sizes depend on their unknown light scattering properties. We consider two cases: bright icy material, and dark dusty material. The icy case better describes the particles if water sublimation from the particles causes a significant rocket force, which we propose as the best method to account for the observed spatial distribution. Solar radiation is a plausible alternative, but only if the particles are very low density aggregates. If we treat the particles as mini-nuclei, we estimate they account for <16-80% of the comet's total water production rate (within 20.6 km). Dark dusty particles, however, are not favored based on mass arguments. The water production rate from bright icy particles is constrained with an upper limit of 0.1 to 0.5% of the total water production rate of the comet. If indeed icy with a high albedo, these particles do not appear to account for the comet's large water production rate. production rate. Erratum: We have corrected the radii and masses of the large particles of comet 103P/Hartley 2 and present revised conclusions in the attached erratum.Comment: Original article: 46 pages, 17 figures, 5 tables, published in Icarus. Erratum: 5 pages, 1 table, accepted for publication in Icaru

Effect of Atmospheric cold Plasma on the Functional Properties of Whole Wheat (Triticum aestivum L.) Grain and Wheat Flour

Atmospheric cold plasma (ACP) has emerged as a novel processing technology, with demonstrated efficiencies in microbial inactivation. However, studies on the effects of ACP and potential to modify the functional properties of foods are sparse. The objective of this study is to determine the effect of ACP on physico-chemical and functional properties of wheat flour. In this study, both whole wheat grains and wheat flour were subjected to a dielectric barrier discharge (DBD) contained plasma reactor for a range of treatment times (5–30 min) at 80 kV. Plasma treatment increased the flour hydration properties of wheat flour. Rapid visco-analyser results showed an increase in pasting and the final viscosities of wheat flour. The decrease in both endothermic enthalpies and crystallinity was attributed to the depolymerization of starch and plasma-induced changes. Overall DBD-ACP treatment can be tailored to develop a plasma process with potential to improve functionality of wheat flour

Linking ozone pollution and climate change: The case for controlling methane

Methane (CH4) emission controls are found to be a powerful lever for reducing both global warming and air pollution via decreases in background tropospheric ozone (O3). Reducing anthropogenic CH4 emissions by 50% nearly halves the incidence of U.S. high-O3 events and lowers global radiative forcing by 0.37 W m−2 (0.30 W m−2 from CH4, 0.07 W m−2 from O3) in a 3-D model of tropospheric chemistry. A 2030 simulation based upon IPCC A1 emissions projections shows a longer and more intense U.S. O3 pollution season despite domestic emission reductions, indicating that intercontinental transport and a rising O3 background should be considered when setting air quality goals

Expert knowledge elicitation to generate human factors guidance for future European rail traffic management system (ERTMS) train driving models

The European Rail Traffic Management System (ERTMS) will have an impact on the train driving task and train driver behaviour. This paper presents part of the final study of series of studies that have been conducted as part of a three-year research project, which investigated the effects of ERTMS on train drivers’ behaviours. In recent times, a number of models of train driving have been developed in order to inform train driving technology design and understand the implications of the design of the train driving task on driver performance and behaviour. An expert knowledge elicitation study was conducted to evaluate existing train driving models and to generate human factors guidance on future ERTMS train driving models. The study consisted of a workshop which was conducted using rail Human Factors (HF) experts who have been directly involved with projects examining ERTMS. Current train driving models were evaluated and ideas generated about how these should be shaped in the future to include systems such as ERTMS. The findings of the study contributed to bridging the gap between the theoretical understanding of train drivers’ cognitive strategies and practical implementation of novel technologies by the rail industry

Partisanship Unmasked? The Role of Politics and Social Norms in COVID-19 Mask-Wearing Behavior

Public health officials have faced resistance in their efforts to promote mask-wearing to counter the spread of COVID-19. One approach to promoting behavior change is to alert people to the fact that a behavior is common (a descriptive norm). However, partisan differences in pandemic mitigation behavior mean that Americans may be especially (in)sensitive to information about behavioral norms depending on the party affiliation of the group in question. In July–August 2020, we tested the effects of providing information to respondents about how many Americans, co-partisans, or out-partisans report wearing masks regularly on both mask-wearing intentions and on the perceived effectiveness of masks. Learning that a majority of Americans report wearing masks regularly increases mask-wearing intentions and perceived effectiveness, though the effects of this information are not distinguishable from other treatments

Recurrence patterns of locally advanced head and neck squamous cell carcinoma after 3D conformal (chemo)-radiotherapy

<p>Abstract</p> <p>Background</p> <p>To establish recurrence patterns among locally advanced head and neck non-nasopharyngeal squamous cell carcinoma (HNSCC) patients treated with radical (chemo-) radiotherapy and to correlate the sites of loco-regional recurrence with radiotherapy doses and target volumes</p> <p>Method</p> <p>151 locally advanced HNSCC patients were treated between 2004-2005 using radical three-dimensional conformal radiotherapy. Patients with prior surgery to the primary tumour site were excluded. The sites of locoregional relapses were correlated with radiotherapy plans by the radiologist and a planning dosimetrist.</p> <p>Results</p> <p>Median age was 59 years (range:34-89). 35 patients had stage III disease, 116 patients had stage IV A/B. 36 patients were treated with radiotherapy alone, 42 with induction chemotherapy, 63 with induction and concomitant chemoradiotherapy and 10 concomitant chemoradiotherapy. Median follow-up was 38 months (range 3-62). 3-year cause specific survival was 66.8%. 125 of 151 (82.8%) achieved a complete response to treatment. Amongst these 125 there were 20 local-regional recurrence, comprising 8 local, 5 regional and 7 simultaneous local and regional; synchronous distant metastases occurred in 7 of the 20. 9 patients developed distant metastases in the absence of locoregional failure. For the 14 local recurrences with planning data available, 12 were in-field, 1 was marginal, and 1 was out-of-field. Of the 11 regional failures with planning data available, 7 were in-field, 1 was marginal and 3 were out-of-field recurrences.</p> <p>Conclusion</p> <p>The majority of failures following non-surgical treatment for locally advanced HNSCC were loco-regional, within the radiotherapy target volume. Improving locoregional control remains a high priority.</p

Expert knowledge elicitation to generate human factors guidance for future European rail traffic management system (ERTMS) train driving models

The European Rail Traffic Management System (ERTMS) will have an impact on the train driving task and train driver behaviour. This paper presents part of the final study of series of studies that have been conducted as part of a three-year research project, which investigated the effects of ERTMS on train drivers’ behaviours. In recent times, a number of models of train driving have been developed in order to inform train driving technology design and understand the implications of the design of the train driving task on driver performance and behaviour. An expert knowledge elicitation study was conducted to evaluate existing train driving models and to generate human factors guidance on future ERTMS train driving models. The study consisted of a workshop which was conducted using rail Human Factors (HF) experts who have been directly involved with projects examining ERTMS. Current train driving models were evaluated and ideas generated about how these should be shaped in the future to include systems such as ERTMS. The findings of the study contributed to bridging the gap between the theoretical understanding of train drivers’ cognitive strategies and practical implementation of novel technologies by the rail industry

Multimodality imaging with CT, MR and FDG-PET for radiotherapy target volume delineation in oropharyngeal squamous cell carcinoma

Background: This study aimed to quantify the variation in oropharyngeal squamous cell carcinoma gross tumour volume (GTV) delineation between CT, MR and FDG PET-CT imaging. Methods: A prospective, single centre, pilot study was undertaken where 11 patients with locally advanced oropharyngeal cancers (2 tonsil, 9 base of tongue primaries) underwent pre-treatment, contrast enhanced, FDG PET-CT and MR imaging, all performed in a radiotherapy treatment mask. CT, MR and CT-MR GTVs were contoured by 5 clinicians (2 radiologists and 3 radiation oncologists). A semi-automated segmentation algorithm was used to contour PET GTVs. Volume and positional analyses were undertaken, accounting for inter-observer variation, using linear mixed effects models and contour comparison metrics respectively. Results: Significant differences in mean GTV volume were found between CT (11.9 cm³) and CT-MR (14.1 cm³), p < 0.006, CT-MR and PET (9.5 cm³), p < 0.0009, and MR (12.7 cm³) and PET, p < 0.016. Substantial differences in GTV position were found between all modalities with the exception of CT-MR and MR GTVs. A mean of 64 %, 74 % and 77 % of the PET GTVs were included within the CT, MR and CT-MR GTVs respectively. A mean of 57 % of the MR GTVs were included within the CT GTV; conversely a mean of 63 % of the CT GTVs were included within the MR GTV. CT inter-observer variability was found to be significantly higher in terms of position and/or volume than both MR and CT-MR (p < 0.05). Significant differences in GTV volume were found between GTV volumes delineated by radiologists (9.7 cm³) and oncologists (14.6 cm³) for all modalities (p = 0.001). Conclusions: The use of different imaging modalities produced significantly different GTVs, with no single imaging technique encompassing all potential GTV regions. The use of MR reduced inter-observer variability. These data suggest delineation based on multimodality imaging has the potential to improve accuracy of GTV definition. Trial registration: ISRCTN Registry: ISRCTN34165059. Registered 2nd February 2015