315 research outputs found
Determinations of bulk density and water retention by soil cores, fragments, and sieved samples
Characterization of the water holding properties of soils has increased in importance. Water in soil is held against gravity by soil suction forces that can be simulated in the laboratory and measured in terms of equivalent negative pressure. The suction force, and measure-ments of the suction force, have been called the soil moisture tension. When free drainage from a wet soil ceases, moisture tension is usually within the range of 0.06 to 0.33 bar and the water content is called field capacity. Water held at tensions between field capacity and 15 bars is generally considered available for plant growth. For most purposes water holding properties of soils are usually expressed in terms of the volume of water held per unit volume of soil at specified energy levels. Water retention measurements of sieved samples are on a weight basis and expression on a volume basis is possible only when the bulk density (dry weight per unit volume of undisturbed soil) is known. Predictions of water holding capacity of soils at specified tensions from measurements with sieved samples and soil cores equilibrated at similar tensions may be erroneous. Crushing and sieving soil may alter the pore size distribution, hence the amount of water held by a sieved sample may differ significantly from the amount held by an undis-turbed sample of equal weight. Predictions of water content on a volume basis from bulk density of undisturbed cores and water content on a weight basis (bulk density x per cent water by weight) may also be inaccurate. The bulk density of cores at the water content at sampling may not be equal to the bulk density of soil at a different water content, i.e. at the predicted tension. This study was initiated to (1) develop a method to measure water content and volume of undisturbed soil fragments after equilibration to a moisture tension in the field capacity range, (2) to study the relation-ship between change in the bulk density of soil with a change in water content, and (3) to study the effect of alternation of pore size on water retention by soil samples equilibrated to a moisture tension in the field capacity range
Estimates of the Costs and Benefits of Expanding the Early Childhood Education Program in Kentucky
Excerpt from the executive summary:
Kentucky officials are being encouraged to expand the availability of Kentucky’s state-funded preschool program. The current program restricts eligibility to three- and four-year-old students with disabilities and four-year-old students with family incomes up to 150 percent of the federal poverty level
Comparison between Tensor Networks and Variational Quantum Classifier
The primary objective of this paper is to conduct a comparative analysis
between two Machine Learning approaches: Tensor Networks (TN) and Variational
Quantum Classifiers (VQC). While both approaches share similarities in their
representation of the Hilbert space using a logarithmic number of parameters,
they diverge in the manifolds they cover. Thus, the aim is to evaluate and
compare the expressibility and trainability of these approaches. By conducting
this comparison, we can gain insights into potential areas where quantum
advantage may be found. Our findings indicate that VQC exhibits advantages in
terms of speed and accuracy when dealing with data, characterized by a small
number of features. However, for high-dimensional data, TN surpasses VQC in
overall classification accuracy. We believe that this disparity is primarily
attributed to challenges encountered during the training of quantum circuits.
We want to stress that in this article, we focus on only one particular task
and do not conduct thorough averaging of the results. Consequently, we
recommend considering the results of this article as a unique case without
excessive generalization
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Development of an Explosive Bonding Process for Producing High Strength Bonds between Niobium and 6061-T651 Aluminum
An explosive bonding procedure for joining 9.5 mm thick niobium plate to 203 mm thick 6061-T651 Al plate has been developed in order to maximize the bond tensile and impact strengths and the amount of bonded material across the surface of the plate. This procedure improves upon previous efforts, in which the 9.5 mm thick niobium plate is bonded directly to 6061-T4 Al plate. In this improved procedure, thin Nb and Al interlayers are explosively clad between the thicker niobium and aluminum plates. Bonds produced using these optimized parameters display a tensile strength of approximately 255 MPa and an impact strength per unit area of approximately 0.148 J/mm{sup 2}. Specialized mechanical testing geometries and procedures are required to measure these bond properties because of the unique bond geometry. In order to ensure that differences in the thermal expansion coefficients of aluminum and niobium do not adversely affect the bond strength, the effects of thermal cycling at temperatures between -22 C and 45 C on the mechanical properties of these bonds have also been investigated by testing samples in both the as-received and thermal cycled conditions. Based on the results obtained from this series of mechanical tests, thermal cycling is shown to have no adverse effect on the resulting tensile and impact strengths of the bonds produced using the optimized bonding parameters
Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas
Matrix metalloproteinases (MMPs) have been implicated as important factors in gliomas since they may both facilitate invasion into the surrounding brain and participate in neovascularization. We have tested the hypothesis that deregulated expression of gelatinase-A or B, or an activator of gelatinase-A, MT1-MMP, may contribute directly to human gliomas by quantifying the expression of these MMPs in 46 brain tumour specimens and seven control tissues. Quantitative RT-PCR and gelatin zymography showed that gelatinase-A in glioma specimens was higher than in normal tissue; these were significantly elevated in low grade gliomas and remained elevated in GBMs. Gelatinase-B transcript and activity levels were also higher than in normal brain and more strongly correlated with tumour grade. We did not see a close relationship between the levels of expression of MT1-MMP mRNA and amounts of activated gelatinase-A. In situ hybridization localized gelatinase-A and MT1-MMP transcripts to normal neuronal and glia, malignant glioma cells and blood vessels. In contrast, gelatinase-B showed a more restricted pattern of expression; it was strongly expressed in blood vessels at proliferating margins, as well as tumour cells in some cases. These data suggest that gelatinase-A, -B and MT1-MMP are important in the pathophysiology of human gliomas. The primary role of gelatinase-B may lie in remodelling associated with neovascularization, whereas gelatinase-A and MT1-MMP may be involved in both glial invasion and angiogenesis. © 1999 Cancer Research Campaig
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Using the relationship between brain tissue regional saturation of oxygen and mean arterial pressure to determine the optimal mean arterial pressure in patients following cardiac arrest: A pilot proof-of-concept study.
INTRODUCTION: Prospectively assess cerebral autoregulation and optimal mean arterial pressure (MAPOPT) using the dynamic relationship between MAP and regional saturation of oxygen (rSO2) using near-infrared spectroscopy. METHODS: Feasibility study of twenty patients admitted to the intensive care unit following a cardiac arrest. All patients underwent continuous rSO2 monitoring using the INVOS(®) cerebral oximeter. ICM+(®) brain monitoring software calculates the cerebral oximetry index (COx) in real-time which is a moving Pearson correlation coefficient between 30 consecutive, 10-s averaged values of MAP and correspond rSO2 signals. When rSO2 increases with increasing MAP (COx ≥0.3), cerebral autoregulation is dysfunctional. Conversely, when rSO2 remains constant or decreases with increasing MAP (COx <0.3), autoregulation is preserved. ICM+(®) fits a U-shaped curve through the COx values plotted vs. MAP. The MAPOPT is nadir of this curve. RESULTS: The median age was 59 years (IQR 54-67) and 7 of 20 were female. The cardiac arrest was caused by myocardial infarction in 12 (60%) patients. Nineteen arrests were witnessed and return of spontaneous circulation occurred in a median of 15.5min (IQR 8-33). Patients underwent a median of 30h (IQR 23-46) of monitoring. COx curves and MAPOPT were generated in all patients. The mean overall MAP and MAPOPT were 76mmHg (SD 10) and 76mmHg (SD 7), respectively. MAP was outside of 5mmHg from MAPOPT in 50% (SD 15) of the time. Out of the 7672 5-min averaged COx measurements, 1182 (15%) were at 0.3 or above, indicating absence of autoregulation. Multivariable polynomial fractional regression demonstrated an increase in COx with increasing temperature (P=0.008). CONCLUSIONS: We demonstrated the feasibility to determine a MAPOPT using cerebral oximetry in patients after cardiac arrest
The role of blocking circulation and emerging open water feedbacks on Greenland cold-season air temperature variability over the last century
Substantial marine, terrestrial, and atmospheric changes have occurred over the Greenland region during the last century. For example, several efforts have documented record-levels of Greenland Ice Sheet (GrIS) summer melt extent and intensity during the 2000s and 2010s, but relatively little work has been carried out to assess regional climatic changes in other seasons. Here, we focus on the less studied cold-season (i.e., autumn and winter) climate, tracing the long-term (1873–2013) variability of Greenland’s air temperatures through analyses of coastal observations and model8 derived outlet glacier series and their linkages with North Atlantic sea ice, sea surface temperature (SST), and atmospheric circulation indices. Through a statistical framework, large amounts of west and south Greenland temperature variance (up to r2~50%) can be explained by the seasonally contemporaneous combination of the Greenland Blocking Index (GBI) and the North Atlantic Oscillation (NAO; hereafter GBI). Lagged and concomitant Baffin sea-ice concentration (SIC) and the Atlantic Multidecadal Oscillation (AMO) seasonal indices account for small amounts of air temperature residual variance (r2<~10%) relative to the GBI. The correlations between GBI and autumn and winter air temperatures are predominantly positive and statistically-significant through time, while Baffin SIC conditions emerge as a significant covariate from the mid-20th century through the conclusion of the study period. The inclusion of the cold-season Pacific Decadal Oscillation (PDO) in multivariate analyses bolsters the air temperature variance explained by the North Atlantic regional predictors, suggesting the remote, background climate state is important to long-term Greenland temperature variability. These findings imply that large-scale tropospheric circulation has a strong control on surface temperature over Greenland through dynamic and thermodynamic impacts and stress the importance of understanding the evolving two-way linkages between the North Atlantic marine and atmospheric environment in order to more accurately predict Greenland seasonal climate variability and change through the 21st century
A retrospective study on the use of post-operative colonoscopy following potentially curative surgery for colorectal cancer in a Canadian province
BACKGROUND: Surveillance colonoscopy is commonly recommended following potentially curative surgery for colorectal cancer. We determined factors associated with patients undergoing a least one colonoscopy within five years of surgery. METHODS: In this historical cohort study, data on 3918 patients age 30 years or older residing in Alberta, Canada, who had undergone a potentially curative surgical resection for local or regional stage colorectal cancer between 1983 and 1995 were obtained from the provincial cancer registry, ministry of health and cancer clinic charts. Kaplan-Meier estimates of the probability of undergoing a post-operative colonoscopy were calculated for patient, tumor and treatment-related variables of interest. RESULTS: A colonoscopy was performed within five years of surgery in 1979 patients. The probability of undergoing a colonoscopy for those diagnosed in the 1990s was greater than for those diagnosed earlier (0.65 vs 0.55, P < 0.0001). The majority of the difference was seen at one-year following surgery, consistent with changes in surveillance practices. Those most likely to undergo a colonoscopy were those under age 70 (0.74 vs 0.50 for those age 70 – 79, P < 0.0001), who underwent a pre-operative colonoscopy (0.69 vs 0.54, P < 0.0001), and who underwent a resection with reanastomosis (0.62 vs 0.47 for abdominoperineal resection, P < 0.0001) by a surgeon who performs colonoscopies (0.68 vs 0.54, P < 0.0001). CONCLUSIONS: The majority of patients undergo colonoscopy following colorectal cancer surgery. However, there are important variations in surveillance practices across different patient and treatment characteristics
Impacts of Hurricanes Katrina and Rita on the microbial landscape of the New Orleans area
Author Posting. © The Author(s), 2007. This is the author's version of the work. It is posted here by permission of National Academy of Sciences of the USA for personal use, not for redistribution. The definitive version was published in Proceedings of the National Academy of Sciences 104 (2007): 9029-9034, doi:10.1073/pnas.0610552104.Floodwaters in New Orleans from Hurricanes Katrina and Rita were observed to contain high levels of fecal indicator bacteria and microbial pathogens, generating concern about long-term impacts of these floodwaters on the sediment and water quality of the New Orleans area and Lake Pontchartrain. We show here that fecal indicator microbe concentrations in offshore waters from Lake Pontchartrain returned to prehurricane concentrations within 2 months of the flooding induced by these hurricanes. Vibrio and Legionella species within the lake were more abundant in samples collected shortly after the floodwaters had receded compared with samples taken within the subsequent 3 months; no evidence of a long-term hurricane-induced algal bloom was observed. Giardia and Cryptosporidium were detected in canal waters. Elevated levels of fecal indicator bacteria observed in sediment could not be solely attributed to impacts from floodwaters, as both flooded and nonflooded areas exhibited elevated levels of fecal indicator bacteria. Evidence from measurements of Bifidobacterium and bacterial diversity analysis suggest that the fecal indicator bacteria observed in the sediment were from human fecal sources. Epidemiologic studies are highly recommended to evaluate the human health effects of the sediments deposited by the floodwaters.This work was funded by NSF-NIEHS Oceans and Human Health Program (NSF OCE0432368, OCE0432479, OCE0430724 and NIEHS P50 ES12736, ES012740, ES012742), the NSF-SGER Program (OCE 0554402, OCE 0554674, OCE 0554850, OCE0600130), the NSF-REU Program, and by the Georgia Sea Grant College Program (NA04OAR170033)
The Teacher, the Physician and the Person: How Faculty's Teaching Performance Influences Their Role Modelling
OBJECTIVE: Previous studies identified different typologies of role models (as teacher/supervisor, physician and person) and explored which of faculty's characteristics could distinguish good role models. The aim of this study was to explore how and to which extent clinical faculty's teaching performance influences residents' evaluations of faculty's different role modelling statuses, especially across different specialties. METHODS: In a prospective multicenter multispecialty study of faculty's teaching performance, we used web-based questionnaires to gather empirical data from residents. The main outcome measures were the different typologies of role modelling. The predictors were faculty's overall teaching performance and faculty's teaching performance on specific domains of teaching. The data were analyzed using multilevel regression equations. RESULTS: In total 219 (69% response rate) residents filled out 2111 questionnaires about 423 (96% response rate) faculty. Faculty's overall teaching performance influenced all role model typologies (OR: from 8.0 to 166.2). For the specific domains of teaching, overall, all three role model typologies were strongly associated with "professional attitude towards residents" (OR: 3.28 for teacher/supervisor, 2.72 for physician and 7.20 for the person role). Further, the teacher/supervisor role was strongly associated with "feedback" and "learning climate" (OR: 3.23 and 2.70). However, the associations of the specific domains of teaching with faculty's role modelling varied widely across specialties. CONCLUSION: This study suggests that faculty can substantially enhance their role modelling by improving their teaching performance. The amount of influence that the specific domains of teaching have on role modelling differs across specialties
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