Improving the phase stability and oxidation resistance of β-NiAl

This thesis is written in an alternate format. The thesis is composed of a general introduction, four original manuscripts, and a general conclusion. References cited within each chapter are located immediately after that section. In addition, figures and tables are numbered independently within each chapter. The general introduction focuses on the driving force behind this research, and gives an overview of previous work done on nickel-based superalloys. Chapter 2 describes the preliminary experiments and how those experiments guided the rest of the thesis work. Chapter 3 deals specifically with the oxidation performance of platinum group metal (PGM) and hafnium modifications to β-NiAl intermetallic. Chapter 4 investigates the role of grain size on the oxidation resistance of NiAl based alloys. Chapter 5 focuses on the role of melting temperature on the oxidation resistance of NiAl based alloys. Chapter 6 summarizes the important results of this study

Group Analysis of Self-organizing Maps based on Functional MRI using Restricted Frechet Means

Studies of functional MRI data are increasingly concerned with the estimation of differences in spatio-temporal networks across groups of subjects or experimental conditions. Unsupervised clustering and independent component analysis (ICA) have been used to identify such spatio-temporal networks. While these approaches have been useful for estimating these networks at the subject-level, comparisons over groups or experimental conditions require further methodological development. In this paper, we tackle this problem by showing how self-organizing maps (SOMs) can be compared within a Frechean inferential framework. Here, we summarize the mean SOM in each group as a Frechet mean with respect to a metric on the space of SOMs. We consider the use of different metrics, and introduce two extensions of the classical sum of minimum distance (SMD) between two SOMs, which take into account the spatio-temporal pattern of the fMRI data. The validity of these methods is illustrated on synthetic data. Through these simulations, we show that the three metrics of interest behave as expected, in the sense that the ones capturing temporal, spatial and spatio-temporal aspects of the SOMs are more likely to reach significance under simulated scenarios characterized by temporal, spatial and spatio-temporal differences, respectively. In addition, a re-analysis of a classical experiment on visually-triggered emotions demonstrates the usefulness of this methodology. In this study, the multivariate functional patterns typical of the subjects exposed to pleasant and unpleasant stimuli are found to be more similar than the ones of the subjects exposed to emotionally neutral stimuli. Taken together, these results indicate that our proposed methods can cast new light on existing data by adopting a global analytical perspective on functional MRI paradigms.Comment: 23 pages, 5 figures, 4 tables. Submitted to Neuroimag

The role of the chair of the school governing body in England

The research reported here analysed the role of the chair of the school governing body in England, drawing on a national survey of governors and the study of governing in 30 schools. The role encompassed: being a governor; appointing and working with the head teacher; acting as a change agent; active participation in the school; organising the governing body; dealing with complaints; working with parents; and chairing meetings. We discuss the role and the way it is experienced and conclude that the position of chair is substantially under-played; given insufficient status; and is a significant educational and community leadership responsibility.17 page(s

The Number Density Evolution of Extreme Emission Line Galaxies in 3D-HST: Results from a Novel Automated Line Search Technique for Slitless Spectroscopy

The multiplexing capability of slitless spectroscopy is a powerful asset in creating large spectroscopic datasets, but issues such as spectral confusion make the interpretation of the data challenging. Here we present a new method to search for emission lines in the slitless spectroscopic data from the 3D-HST survey utilizing the Wide-Field Camera 3 on board the Hubble Space Telescope. Using a novel statistical technique, we can detect compact (extended) emission lines at 90% completeness down to fluxes of 1.5 (3.0) times 10^{-17} erg/s/cm^2, close to the noise level of the grism exposures, for objects detected in the deep ancillary photometric data. Unlike previous methods, the Bayesian nature allows for probabilistic line identifications, namely redshift estimates, based on secondary emission line detections and/or photometric redshift priors. As a first application, we measure the comoving number density of Extreme Emission Line Galaxies (restframe [O III] 5007 equivalent widths in excess of 500 Angstroms). We find that these galaxies are nearly 10 times more common above z~1.5 than at z<0.5. With upcoming large grism surveys such as Euclid and WFIRST as well as grisms featuring prominently on the NIRISS and NIRCam instruments on James Webb Space Telescope, methods like the one presented here will be crucial for constructing emission line redshift catalogs in an automated and well-understood manner.Comment: 16 pages, 14 Figures; Accepted to Ap

Ages of massive galaxies at 0.5<z<2.00.5 < z < 2.0 from 3D-HST rest-frame optical spectroscopy

We present low-resolution near-infrared stacked spectra from the 3D-HST survey up to $z=2.0$ and fit them with commonly used stellar population synthesis models: BC03 (Bruzual & Charlot, 2003), FSPS10 (Flexible Stellar Population Synthesis, Conroy & Gunn 2010), and FSPS-C3K (Conroy, Kurucz, Cargile, Castelli, in prep). The accuracy of the grism redshifts allows the unambiguous detection of many emission and absorption features, and thus a first systematic exploration of the rest-frame optical spectra of galaxies up to $z=2$. We select massive galaxies ($\rm log(M_{*} / M_{\odot}) > 10.8$), we divide them into quiescent and star-forming via a rest-frame color-color technique, and we median-stack the samples in 3 redshift bins between $z=0.5$ and $z=2.0$. We find that stellar population models fit the observations well at wavelengths below $\rm 6500 \AA$ rest-frame, but show systematic residuals at redder wavelengths. The FSPS-C3K model generally provides the best fits (evaluated with a $\chi^2_{red}$ statistics) for quiescent galaxies, while BC03 performs the best for star-forming galaxies. The stellar ages of quiescent galaxies implied by the models, assuming solar metallicity, vary from 4 Gyr at $z \sim 0.75$ to 1.5 Gyr at $z \sim 1.75$, with an uncertainty of a factor of 2 caused by the unknown metallicity. On average the stellar ages are half the age of the Universe at these redshifts. We show that the inferred evolution of ages of quiescent galaxies is in agreement with fundamental plane measurements, assuming an 8 Gyr age for local galaxies. For star-forming galaxies the inferred ages depend strongly on the stellar population model and the shape of the assumed star-formation history.Comment: 13 pages, 15 figures, accepted for publication in Ap

JWST/NIRSpec Measurements of the Relationships Between Nebular Emission-line Ratios and Stellar Mass at z~3-6

We analyze the rest-optical emission-line ratios of star-forming galaxies at 2.7<=z<6.5 drawn from the Cosmic Evolution Early Release Science (CEERS) Survey, and their relationships with stellar mass (M_*). Our analysis includes both line ratios based on the [NII]6583 feature -- [NII]6583/Ha, ([OIII]5007/Hb)/([NII]6583/Ha) (O3N2), and [NII]6583/[OII]3727 -- and those those featuring alpha elements -- [OIII]5007/Hb, [OIII]5007/[OII]3727 (O_32), ([OIII]4959,5007+[OII]3727)/Hb (R_23), and [NeIII]3869/[OII]3727. Given the typical flux levels of [NII]6583 and [NeIII]3869, which are undetected in the majority of individual CEERS galaxies at 2.7<=z<6.5, we construct composite spectra in bins of M_* and redshift. Using these composite spectra, we compare the relationships between emission-line ratios and M_* at 2.7<=z<6.5 with those observed at lower redshift. While there is significant evolution towards higher excitation (e.g., higher [OIII]5007/Hb, O_32, O3N2), and weaker nitrogen emission (e.g., lower [NII]6583/Ha and [NII]6583/[OII]3727) between z~0 and z~3, we find in most cases that there is no significant evolution in the relationship between line ratio and M_* beyond z~3. The [NeIII]3869/[OII]3727 ratio is anomalous in showing evidence for significant elevation at 4.0<=z<6.5 at fixed mass, relative to z~3.3. Collectively, however, our empirical results suggest that there is no significant evolution in the mass-metallicity relationship at 2.7<=z<6.5. Representative galaxy samples and metallicity calibrations based on existing and upcoming JWST/NIRSpec observations will be required to translate these empirical scaling relations into ones tracing chemical enrichment and gas cycling, and distinguish among the descriptions of star-formation feedback in simulations of galaxy formation at z>3.Comment: 10 pages, 4 figures, ApJL, in pres

JWST/NIRSpec Balmer-line Measurements of Star Formation and Dust Attenuation at z~3-6

We present an analysis of the star-formation rates (SFRs) and dust attenuation properties of star-forming galaxies at $2.7\leq z<6.5$ drawn from the Cosmic Evolution Early Release Science (CEERS) Survey. Our analysis is based on {\it JWST}/NIRSpec Micro-Shutter Assembly (MSA) $R\sim1000$ spectroscopic observations covering approximately $1-5$$\mu$m. Our primary rest-frame optical spectroscopic measurements are H$\alpha$/H$\beta$ Balmer decrements, which we use as an indicator of nebular dust attenuation. In turn, we use Balmer decrements to obtain dust-corrected H$\alpha$-based SFRs (i.e., SFR(H$\alpha$)). We construct the relationship between SFR(H$\alpha$) and stellar mass ($M_*$) in three bins of redshift ($2.7\leq z< 4.0$, $4.0\leq z< 5.0$, and $5.0\leq z<6.5$), which represents the first time the star-forming main sequence has been traced at these redshifts using direct spectroscopic measurements of Balmer emission as a proxy for SFR. In tracing the relationship between SFR(H$\alpha$) and $M_*$ back to such early times ($z>3$), it is essential to use a conversion factor between H$\alpha$ and SFR that accounts for the subsolar metallicity prevalent among distant galaxies. We also use measured Balmer decrements to investigate the relationship between dust attenuation and stellar mass out to $z\sim6$. The lack of significant redshift evolution in attenuation at fixed stellar mass, previously confirmed using Balmer decrements out to $z\sim2.3$, appears to hold out to $z\sim 6.5$. Given the rapidly evolving gas, dust, and metal content of star-forming galaxies at fixed mass, this lack of significant evolution in attenuation provides an ongoing challenge to explain.Comment: 9 pages, 4 figures, ApJ, in pres

Epigenetic mediation of AKT1 rs1130233's Effect on delta-9-tetrahydrocannabinol-induced medial temporal function during fear processing

High doses of delta-9-tetrahydrocannabinol (THC), the main psychoactive component of cannabis, have been shown to have anxiogenic effects. Additionally, THC effects have been shown to be modulated by genotype, including the single nucleotide polymorphism (SNP) rs1130233 at the protein kinase AKT1 gene, a key component of the dopamine signalling cascade. As such, it is likely that epigenetic methylation around this SNP may affect AKT gene expression, which may in turn impact on the acute effects of THC on brain function. We investigated the genetic (AKT1 rs1130233) and epigenetic modulation of brain function during fear processing in a 2-session, double-blind, cross-over, randomized placebo-controlled THC administration, in 36 healthy males. Fear processing was assessed using an emotion (fear processing) paradigm, under functional magnetic resonance imaging (fMRI). Complete genetic and fMRI data were available for 34 participants. THC caused an increase in anxiety and transient psychotomimetic symptoms and para-hippocampal gyrus/amygdala activation. Number of A alleles at the AKT1 rs1130233 SNP, and percentage methylation at the CpG11-12 site, were independently associated with a greater effect of THC on activation in a network of brain regions including left and right parahippocampal gyri, respectively. AKT1 rs1130233 moderation of the THC effect on left parahippocampal activation persisted after covarying for methylation percentage, and was partially mediated in sections of the left parahippocampal gyrus/hippocampus by methylation percentage. These results may offer an example of how genetic and epigenetic variations influence the psychotomimetic and neurofunctional effects of THC