210 research outputs found
A Collaboration-based Approach to Service Specification and Detection of Implied Scenarios
ABSTRACT Methods for service specification should be simple and intuitive. At the same time they should be precise and allow early validations to be performed, in order to detect inconsistencies as early as possible in the service development cycle. In this paper we present a service specification approach based on UML 2.0 collaborations. It aims to be a constructive approach, rather than a corrective one, as it is intended to promote understanding and help reducing the number of specification errors. We also address the detection of implied scenarios from collaboration-based service specifications, and propose an approach that limits the state explosion problem. This is possible since the detection analysis is modular and it is performed at a high-level of abstraction
Onzekere milieurisico's. Een onderzoek naar de wijze van omgaan met onzekere milieurisico's door de wetgever, het bestuur en de rechter. Deel 2: Praktijkonderzoek (STEM-project)
Single molecule investigation of the onset and minimum size of the calcium-mediated junction zone in alginate
One of the principal roles of alginate, both natively and in commercial applications, is gelation via Ca2+-mediated crosslinks between blocks of guluronic acid. In this work, single molecule measurements were carried out between well-characterised series of nearly monodisperse guluronic acid blocks (‘oligoGs’) using dynamic force spectroscopy. The measurements provide evidence that for interaction times on the order of tens of milliseconds the maximum crosslink strength is achieved by pairs of oligoGs long enough to allow the coordination of 4 Ca2+ ions, with both shorter and longer oligomers forming weaker links. Extending the interaction time from tens to hundreds of milliseconds allows longer oligoGs to achieve much stronger crosslinks but does not change the strength of individual links between shorter oligoGs. These results are considered in light of extant models for the onset of cooperative crosslinking in polyelectrolytes and an anisotropic distribution of oligoGs on interacting surfaces and provide a timescale for the formation and relaxation of alginate gels at the single crosslink level
Effect of cross-linked biodegradable polymers on sustained release of sodium diclofenac-loaded microspheres
A study of the BTEX/VOCs emission from glycol dehydration units
EThOS - Electronic Theses Online ServiceGBUnited Kingdo
Visiting Professor presso Sapienza
-Polysaccharide engineering as an approach to design alginate with new functional properties.
-Alginate encapsulate cells in the treatment of type I diabetes
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