1,662 research outputs found
Formation of seasonal groups and application of seasonal indices
Estimating seasonal variations in demand is a challenging task faced by many organisations. There may be many stock-keeping units (SKUs) to forecast, but often data histories are short, with very few complete seasonal cycles. It has been suggested in the literature that group seasonal indices (GSI) methods should be used to take advantage of information on similar SKUs. This paper addresses two research questions: (1) how should groups be formed in order to use the GSI methods? and (2) when should the GSI methods and the individual seasonal indices (ISI) method be used? Theoretical results are presented, showing that seasonal grouping and forecasting may be unified, based on a Mean Square Error criterion, and K-means clustering. A heuristic K-means method is presented, which is competitive with the Average Linkage method. It offers a viable alternative to a company’s own grouping method or may be used with confidence if a company lacks a grouping method. The paper gives empirical findings that confirm earlier theoretical results that greater
accuracy may be obtained by employing a rule that assigns the GSI method to some SKUs and the ISI method to the remainder
Reproducibility in forecasting research
The importance of replication has been recognised across many scientific disciplines. Reproducibility is a necessary condition for replicability, because an inability to reproduce results implies that the methods have not been specified sufficiently, thus precluding replication. This paper describes how two independent teams of researchers attempted to reproduce the empirical findings of an important paper, ‘‘Shrinkage estimators of time series seasonal factors and their effect on forecasting accuracy’’ (Miller & Williams, 2003). The two teams proceeded systematically, reporting results both before and after receiving clarifications from the authors of the original study. The teams were able to approximately reproduce each other’s results, but not those of Miller and Williams. These discrepancies led to differences in the conclusions as to the conditions under which seasonal damping outperforms classical decomposition. The paper specifies the forecasting methods employed using a flowchart. It is argued that this approach to method documentation is complementary to the provision of computer code, as it is accessible to a broader audience of forecasting
practitioners and researchers. The significance of this research lies not only in its lessons for seasonal forecasting but also, more generally, in its approach to the reproduction of
forecasting research
Supply chain forecasting when information is not shared
The operations management literature is abundant in discussions on the benefits of information sharing in supply chains. However, there are many supply chains where information may not be shared due to constraints such as compatibility of information systems, information quality, trust and confidentiality. Furthermore, a steady stream of papers has explored a phenomenon known as Downstream Demand Inference (DDI) where the upstream member in a supply chain can infer the downstream demand without the need for a formal information sharing mechanism. Recent research has shown that, under more realistic circumstances, DDI is not possible with optimal forecasting methods or Single Exponential Smoothing but is possible when supply chains use a Simple Moving Average (SMA) method. In this paper, we evaluate a simple DDI strategy based on SMA for supply chains where information cannot be shared. This strategy allows the upstream member in the supply chain to infer the consumer demand mathematically rather than it being shared. We compare the DDI strategy with the No Information Sharing (NIS) strategy and an optimal Forecast Information Sharing (FIS) strategy in the supply chain. The comparison is made analytically and by experimentation on real sales data from a major European supermarket located in Germany. We show that using the DDI strategy improves on NIS by reducing the Mean Square Error (MSE) of the forecasts, and cutting inventory costs in the supply chain
The origin of ultra diffuse galaxies: stellar feedback and quenching
We test if the cosmological zoom-in simulations of isolated galaxies from the
FIRE project reproduce the properties of ultra diffuse galaxies. We show that
stellar feedback-generated outflows that dynamically heat galactic stars,
together with a passively aging stellar population after imposed quenching
(from e.g. infall into a galaxy cluster), naturally reproduce the observed
population of red UDGs, without the need for high spin halos or dynamical
influence from their host cluster. We reproduce the range of surface
brightness, radius and absolute magnitude of the observed z=0 red UDGs by
quenching simulated galaxies at a range of different times. They represent a
mostly uniform population of dark matter-dominated galaxies with M_star ~1e8
Msun, low metallicity and a broad range of ages. The most massive simulated
UDGs require earliest quenching and are therefore the oldest. Our simulations
provide a good match to the central enclosed masses and the velocity
dispersions of the observed UDGs (20-50 km/s). The enclosed masses of the
simulated UDGs remain largely fixed across a broad range of quenching times
because the central regions of their dark matter halos complete their growth
early. A typical UDG forms in a dwarf halo mass range of Mh~4e10-1e11 Msun. The
most massive red UDG in our sample requires quenching at z~3 when its halo
reached Mh ~ 1e11 Msun. If it, instead, continues growing in the field, by z=0
its halo mass reaches > 5e11 Msun, comparable to the halo of an L* galaxy. If
our simulated dwarfs are not quenched, they evolve into bluer low-surface
brightness galaxies with mass-to-light ratios similar to observed field dwarfs.
While our simulation sample covers a limited range of formation histories and
halo masses, we predict that UDG is a common, and perhaps even dominant, galaxy
type around Ms~1e8 Msun, both in the field and in clusters.Comment: 20 pages, 13 figures; match the MNRAS accepted versio
From flexible to restricted mathematics: 15 years of Ofsted mathematics reports
The Office for Standards in Education (Ofsted), the school inspectorate service in England, has a great impact on education through their inspections but also through their subject reports. The authors undertook a document analysis of five mathematics subject reports produced by Ofsted from 2008 to 2023, identifying commonalities and convergence, particularly focusing on problem solving, calculation and the role of talk. The older reports were found to take a more flexible approach to mathematics that continues to be supported by several mathematics education subject organisations. The recent reports took a more restricted view of learning mathematics, seeing it as a set of memorisable procedures
A fitting formula for the merger timescale of galaxies in hierarchical clustering
We study galaxy mergers using a high-resolution cosmological hydro/N-body
simulation with star formation, and compare the measured merger timescales with
theoretical predictions based on the Chandrasekhar formula. In contrast to
Navarro et al., our numerical results indicate, that the commonly used equation
for the merger timescale given by Lacey and Cole, systematically underestimates
the merger timescales for minor mergers and overestimates those for major
mergers. This behavior is partly explained by the poor performance of their
expression for the Coulomb logarithm, \ln (m_pri/m_sat). The two alternative
forms \ln (1+m_pri/m_sat) and 1/2\ln [1+(m_pri/m_sat)^2] for the Coulomb
logarithm can account for the mass dependence of merger timescale successfully,
but both of them underestimate the merger time scale by a factor 2. Since \ln
(1+m_pri/m_sat) represents the mass dependence slightly better we adopt this
expression for the Coulomb logarithm. Furthermore, we find that the dependence
of the merger timescale on the circularity parameter \epsilon is much weaker
than the widely adopted power-law \epsilon^{0.78}, whereas
0.94*{\epsilon}^{0.60}+0.60 provides a good match to the data. Based on these
findings, we present an accurate and convenient fitting formula for the merger
timescale of galaxies in cold dark matter models.Comment: 16 pages, 14 figures, accepted for publication in ApJ, minor changes
in the last few sentences of the discussio
Crocidolite asbestos induces apoptosis of pleural mesothelial cells: role of reactive oxygen species and poly(ADP-ribosyl) polymerase.
Mesothelial cells, the progenitor cells of the asbestos-induced tumor mesothelioma, are particularly sensitive to the toxic effects of asbestos, although the molecular mechanisms by which asbestos induces injury in mesothelial cells are not known. We asked whether asbestos induced apoptosis in mesothelial cells and whether reactive oxygen species were important. Rabbit pleural mesothelial cells were exposed to crocidolite asbestos or control particles (1-10 micrograms/cm2) over 24 hr and evaluated for oligonucleosomal DNA fragmentation, loss of membrane phospholipid asymmetry, and nuclear condensation. Asbestos fibers, not control particles, induced apoptosis in mesothelial cells by all assays. Induction of apoptosis was dose dependent; crocidolite (5 micrograms/cm2) induced apoptosis (15.0 +/- 1.1%, mean +/- SE; n = 12) versus control particles (< 4%), as measured by appearance of nuclear condensation. Apoptosis induced by asbestos, but not by actinomycin D, was inhibited by extracellular catalase, superoxide dismutase in the presence of catalase, hypoxia (8% oxygen), deferoxamine, and 3-aminobenzamide (an inhibitor of the nuclear enzyme, poly(adenosine diphosphate-ribosyl) polymerase). We conclude that asbestos induces apoptosis in mesothelial cells via reactive oxygen species. We speculate that escape from this pathway could allow the abnormal survival of mesothelial cells with asbestos-induced mutations
Development and Pilot of a Checklist for Management of Acute Liver Failure in the Intensive Care Unit
Introduction
Acute liver failure (ALF) is an ideal condition for use of a checklist. Our aims were to develop a checklist for the management of ALF in the intensive care unit (ICU) and assess the usability of the checklist among multiple providers.
Methods
The initial checklist was developed from published guidelines and expert opinion. The checklist underwent pilot testing at 11 academic liver transplant centers in the US and Canada. An anonymous, written survey was used to assess the usability and quality of the checklist. Written comments were used to improve the checklist following the pilot testing period.
Results
We received 81 surveys involving the management of 116 patients during the pilot testing period. The overall quality of the checklist was judged to be above average to excellent by 94% of users. On a 5-point Likert scale, the majority of survey respondents agreed or agreed strongly with the following checklist characteristics: the checklist was easy to read (99% agreed/agreed strongly), easy to use (97%), items are categorized logically (98%), time to complete the checklist did not interfere with delivery of appropriate and safe patient care (94%) and was not excessively burdensome (92%), the checklist allowed the user the freedom to use his or her clinical judgment (80%), it is a useful tool in the management of acute liver failure (98%). Web-based and mobile apps were developed for use of the checklist at the point of care.
Conclusion
The checklist for the management of ALF in the ICU was shown in this pilot study to be easy to use, helpful and accepted by a wide variety of practitioners at multiple sites in the US and Canada
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