American Apparel Advertisements

American Apparel advertisements are deemed offensive and controversial and many of their ads have been banned due to its presentation of women. Despite the controversy, there has been no sociological study on how gender is presented in their ads. This thesis explores how men and women are presented in twelve of their print ads

Mass community cycling events: Who participates and is their behaviour influenced by participation?

BACKGROUND: Participation in mass physical activity events may be a novel approach for encouraging inactive or low active adults to trial an active behaviour. The public health applicability of this strategy has not been investigated thoroughly. The purpose of this study to was describe participants in a mass cycling event and examine the subsequent effect on cycling behaviour. METHODS: A sample of men and women aged 16 years and older (n = 918) who registered online for a mass cycling event reported cycling ability and number of times they rode a bicycle during the month before the event. One month after the event participants completed an online follow-up questionnaire and reported cycling ability, lifestyle physical activity, and number of times they rode a bicycle during the month after the event. McNemar's test was used to examine changes in self-rated cycling ability, and repeated measures mixed linear modeling was used to determine whether average number of monthly bicycle rides changed between pre-event and post-event assessment. RESULTS: Participants in the cycling event were predominantly male (72%), 83% rated themselves as competent or regular cyclists, and 68% rated themselves as more active than others of the same sex and age. Half of the survey respondents that rated their cycling ability as low before the event subsequently rated themselves as high one month after the event. Respondents with low pre-event self-rated cycling ability reported an average 4 sessions of bicycle riding the month before the event and an average 6.8 sessions of bicycle riding a month after the event. This increase in average sessions of bicycle riding was significant (p < .0001). Similarly, first-time participants in this particular cycling event significantly increased average sessions of cycling from 7.2 pre-event to 8.9 sessions one month after the event. CONCLUSION: Participants who were novice riders or first time participants significantly increased their number of bicycle rides in the month after the event. Further knowledge about the public health applicability of mass events is needed, and methods for attracting less active and novice individuals to participate remain to be developed

An edition of 'The Tragedie of Cleopatra' by Samuel Daniel

Although highly regarded - and much published - in his lifetime, the poet, literary critic and historian, Samuel Daniel is now overshadowed by his contemporary, William Shakespeare. Interest in this late Elizabethan / early Jacobean writer has been restricted by the lack of a complete critical edition of Daniel's works, a gap which no single thesis could attempt to fill. One problem facing prospective editors has been Daniel's propensity for amending pieces as they went through successive editions. An additional difficulty for an editor is that few of his works were presented in a stand-alone format even in their initial presentation to the reading public. This thesis offers a scholarly edition of one of Daniel's earliest pieces, 'The Tragedie of Cleopatra' . It argues that 'Cleopatra' transcends the label 'closet drama' that is often attached to it which has overshadowed recognition of its literary merits and the political, philosophical and religious concerns of its period which it addresses. In addition, Shakespeare's 'Antony and Cleopatra', written more than a decade later, has captured the attention of critics and audiences. Whilst I acknowledge these points, I position 'Cleopatra' as an important work from the late Elizabethan period. By including an overview of related works and paratextual material by Daniel, I provide insight into his life and a context for the play. I consider also the source material available to Daniel and detail how he was influenced by and utilised Plutarch's 'Lives'. It is my intention that through this thesis, 'The Tragedie of Cleopatra' will become available as a resource for both students and scholars. The copytext for my annotated edition of the tragedy is the Blickling Hall copy of 'The works of Samuel Daniel newly augmented' (London, 1601) and I include variants from those editions of the tragedy which were published in the period 1594-1605

Antimicrobial activity, cytotoxicity and chemical analysis of lemongrass essential oil (Cymbopogon flexuosus) and pure citral

© 2016, The Author(s). The aim of this study was to determine the antimicrobial effects of lemongrass essential oil (C. flexuosus) and to determine cytotoxic effects of both test compounds on human dermal fibroblasts. Antimicrobial susceptibility screening was carried out using the disk diffusion method. Antimicrobial resistance was observed in four of five Acinetobacter baumannii strains with two strains confirmed as multi-drug-resistant (MDR). All the strains tested were susceptible to both lemongrass and citral with zones of inhibition varying between 17 to 80mm. The mean minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of citral (mic—0.14% and mbc—0.3%v/v) was lower than that of Lemongrass (mic—0.65% and mbc—1.1%v/v) determined using the microtitre plate method. Cell viability using human dermal fibroblasts (HDF; 106-05a) was determined following exposure to both compounds and a control (Grapeseed oil) using the XTT assay and the IC50 determined at 0.095% (v/v) for citral and 0.126% (v/v) for lemongrass. Grapeseed oil had no effect on cell viability. Live cell imaging was performed using the LumaScope 500 imaging equipment and changes in HDF cell morphology such as necrotic features and shrinkage were observed. The ability of lemongrass essential oil (EO) and citral to inhibit and kill MDR A. baumannii highlights its potential for use in the management of drug-resistant infections; however, in vitro cytotoxicity does suggest further tests are needed before in vivo or ex vivo human exposure

Walking behaviours from the 1965–2003 American Heritage Time Use Study (AHTUS)

<p>Abstract</p> <p>Background</p> <p>The American Heritage Time Use Study (AHTUS) represents a harmonised historical data file of time use by adults, amalgamating surveys collected in 1965–66, 1975–76, 1985, 1992–94, and 2003. The objectives of time-use studies have ranged from evaluating household and other unpaid production of goods and services, to monitoring of media use, to comparing lifestyles of more and less privileged social groups, or to tracking broad shifts in social behaviour. The purpose of this paper is to describe the process and utility of identifying and compiling data from the AHTUS to describe a range of walking behaviours collected using time-use survey methods over almost 40 years in the USA.</p> <p>Methods</p> <p>This is a secondary data analysis of an existing amalgamated data set. Noting source survey-specific limitations in comparability of design, we determined age-standardized participation (and associated durations) in any walking, walking for exercise, walking for transport, walking the dog, sports/exercise (excluding walking), and all physical activity for those survey years for which sufficient relevant data details were available.</p> <p>Results</p> <p>Data processing revealed inconsistencies in instrument administration, coding various types of walking and in prompting other sport/exercise across surveys. Thus for the entire period, application of inferential statistics to determine trend for a range of walking behaviours could not be done with confidence. Focusing on the two most comparable survey years, 1985 and 2003, it appears that walking for exercise in America has increased in popularity on any given day (from 2.9 to 5.4% of adults) and accumulated duration amongst those who walk for exercise (from 30 to 45 mins/day). Dog walking has decreased in popularity over the same time period (from 9.4 to 2.6%). Associated duration amongst dog walkers was stable at 30 mins/day.</p> <p>Conclusion</p> <p>The noted and sometimes substantial differences in methods between the various survey administrations preclude stringent interpretation of these trends in walking behaviours and the use of conventional application of inferential statistics to evaluate significance of time trends. Although the AHTUS offers the most comprehensive attempt at harmonization yet undertaken with these individual time-use surveys, we found that any noted cross-time changes in walking and physical activity behaviour are not easily interpreted in terms of conventional epidemiological approaches and could be true changes, artefact related to instrument and method changes, or both. Public health utilization of the AHTUS, could be enhanced with greater attention to methodological issues known to influence estimation of physical activity behaviour in population. This could be achieved with cross-disciplinary collaboration between groups of experts in the various stages of these surveys.</p

The International Prevalence Study on Physical Activity: results from 20 countries

<p>Abstract</p> <p>Background</p> <p>Physical activity (PA) is one of the most important factors for improving population health, but no standardised systems exist for international surveillance. The International Physical Activity Questionnaire (IPAQ) was developed for international surveillance. The purpose of this study was a comparative international study of population physical activity prevalence across 20 countries.</p> <p>Methods</p> <p>Between 2002–2004, a standardised protocol using IPAQ was used to assess PA participation in 20 countries [total N = 52,746, aged 18–65 years]. The median survey response rate was 61%. Physical activity levels were categorised as "low", "moderate" and "high". Age-adjusted prevalence estimates are presented by sex.</p> <p>Results</p> <p>The prevalence of "high PA" varied from 21–63%; in eight countries high PA was reported for over half of the adult population. The prevalence of "low PA" varied from 9% to 43%. Males more frequently reported high PA than females in 17 of 20 countries. The prevalence of low PA ranged from 7–41% among males, and 6–49% among females. Gender differences were noted, especially for younger adults, with males more active than females in most countries. Markedly lower physical activity prevalence (10% difference) with increasing age was noted in 11 of 19 countries for males, but only in three countries for women. The ways populations accumulated PA differed, with some reporting mostly vigorous intensity activities and others mostly walking.</p> <p>Conclusion</p> <p>This study demonstrated the feasibility of international PA surveillance, and showed that IPAQ is an acceptable surveillance instrument, at least within countries. If assessment methods are used consistently over time, trend data will inform countries about the success of their efforts to promote physical activity.</p

Improving quality of breast cancer surgery through development of a national breast cancer surgical outcomes (BRCASO) research database

<p>Abstract</p> <p>Background</p> <p>Common measures of surgical quality are 30-day morbidity and mortality, which poorly describe breast cancer surgical quality with extremely low morbidity and mortality rates. Several national quality programs have collected additional surgical quality measures; however, program participation is voluntary and results may not be generalizable to all surgeons. We developed the Breast Cancer Surgical Outcomes (BRCASO) database to capture meaningful breast cancer surgical quality measures among a non-voluntary sample, and study variation in these measures across providers, facilities, and health plans. This paper describes our study protocol, data collection methods, and summarizes the strengths and limitations of these data.</p> <p>Methods</p> <p>We included 4524 women ≥18 years diagnosed with breast cancer between 2003-2008. All women with initial breast cancer surgery performed by a surgeon employed at the University of Vermont or three Cancer Research Network (CRN) health plans were eligible for inclusion. From the CRN institutions, we collected electronic administrative data including tumor registry information, Current Procedure Terminology codes for breast cancer surgeries, surgeons, surgical facilities, and patient demographics. We supplemented electronic data with medical record abstraction to collect additional pathology and surgery detail. All data were manually abstracted at the University of Vermont.</p> <p>Results</p> <p>The CRN institutions pre-filled 30% (22 out of 72) of elements using electronic data. The remaining elements, including detailed pathology margin status and breast and lymph node surgeries, required chart abstraction. The mean age was 61 years (range 20-98 years); 70% of women were diagnosed with invasive ductal carcinoma, 20% with ductal carcinoma in situ, and 10% with invasive lobular carcinoma.</p> <p>Conclusions</p> <p>The BRCASO database is one of the largest, multi-site research resources of meaningful breast cancer surgical quality data in the United States. Assembling data from electronic administrative databases and manual chart review balanced efficiency with high-quality, unbiased data collection. Using the BRCASO database, we will evaluate surgical quality measures including mastectomy rates, positive margin rates, and partial mastectomy re-excision rates among a diverse, non-voluntary population of patients, providers, and facilities.</p

Risk of Heart Failure in Breast Cancer Patients After Anthracycline and Trastuzumab Treatment: A Retrospective Cohort Study

Background: Clinical trials demonstrated that women treated for breast cancer with anthracycline or trastuzumab are at increased risk for heart failure and/or cardiomyopathy (HF/CM), but the generalizability of these findings is unknown. We estimated real-world adjuvant anthracycline and trastuzumab use and their associations with incident HF/CM. Methods We conducted a population-based, retrospective cohort study of 12 500 women diagnosed with incident, invasive breast cancer from January 1, 1999 through December 31, 2007, at eight integrated Cancer Research Network health systems. Using administrative procedure and pharmacy codes, we identified anthracycline, trastuzumab, and other chemotherapy use. We identified incident HF/CM following chemotherapy initiation and assessed risk of HF/CM with time-varying chemotherapy exposures vs no chemotherapy. Multivariable Cox proportional hazards regression models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) with adjustment for age at diagnosis, stage, Cancer Research Network site, year of diagnosis, radiation therapy, and comorbidities. Results: Among 12 500 women (mean age &#x003D; 60 years, range &#x003D; 22–99 years), 29.6% received anthracycline alone, 0.9% received trastuzumab alone, 3.5% received anthracycline plus trastuzumab, 19.5% received other chemotherapy, and 46.5% received no chemotherapy. Anthracycline and trastuzumab recipients were younger, with fewer comorbidities than recipients of other chemotherapy or none. Compared with no chemotherapy, the risk of HF/CM was higher in patients treated with anthracycline alone (adjusted HR &#x003D; 1.40, 95% CI &#x003D; 1.11 to 1.76), although the increased risk was similar to other chemotherapy (adjusted HR &#x003D; 1.49, 95% CI &#x003D; 1.25 to 1.77); the risk was highly increased in patients treated with trastuzumab alone (adjusted HR &#x003D; 4.12, 95% CI &#x003D; 2.30 to 7.42) or anthracycline plus trastuzumab (adjusted HR &#x003D; 7.19, 95% CI &#x003D; 5.00 to 10.35). Conclusions: Anthracycline and trastuzumab were primarily used in younger, healthier women and associated with increased HF/CM risk compared with no chemotherapy. This population-based observational study complements findings from clinical trials on cancer treatment safety

Patterns of neighborhood environment attributes related to physical activity across 11 countries: A latent class analysis

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