70 research outputs found
SociologĂa y filosofĂa
QuisiĂ©ramos precisar las relaciones de la filosofĂa con la sociologĂa utilizando, sobre todo, los resultados obtenidos por la escuela que se ha agrupado en Francia en torno de Emilio Durkheim, fundador de L’AnnĂ©e Sociologique. Bien cierto es que, para alcanzar la debida precisiĂłn, corresponderĂa definir con exactitud esos dos tĂ©rminos. Y con ello aparece la primera dificultad, especialmente al tratarse de la filosofĂa, de su objeto y de su mĂ©todo. Definir es elegir: hasta podrĂa decirse que definir es concluir.Conferencia dada en el Aula Mayor el 22 de agosto de 1928.Facultad de Humanidades y Ciencias de la EducaciĂł
Large-scale mapping of bioactive peptides in structural and sequence space
Health-enhancing potential bioactive peptide (BP) has driven an interest in food proteins as well as in the development of predictive methods. Research in this area has been especially active to use them as components in functional foods. Apparently, BPs do not have a given biological function in the containing proteins and they do not evolve under independent evolutionary constraints. In this work we performed a large-scale mapping of BPs in sequence and structural space. Using well curated BP deposited in BIOPEP database, we searched for exact matches in non-redundant sequences databases. Proteins containing BPs, were used in fold-recognition methods to predict the corresponding folds and BPs occurrences were mapped. We found that fold distribution of BP occurrences possibly reflects sequence relative abundance in databases. However, we also found that proteins with 5 or more than 5 BP in their sequences correspond to well populated protein folds, called superfolds. Also, we found that in well populated superfamilies, BPs tend to adopt similar locations in the protein fold, suggesting the existence of hotspots. We think that our results could contribute to the development of new bioinformatics pipeline to improve BP detection.Fil: Nardo, Agustina Estefania. Provincia de Buenos Aires. GobernaciĂłn. ComisiĂłn de Investigaciones CientĂficas. Centro de InvestigaciĂłn y Desarrollo en CriotecnologĂa de Alimentos. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - La Plata. Centro de InvestigaciĂłn y Desarrollo en CriotecnologĂa de Alimentos. Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de InvestigaciĂłn y Desarrollo en CriotecnologĂa de Alimentos; ArgentinaFil: Añon, Maria Cristina. Provincia de Buenos Aires. GobernaciĂłn. ComisiĂłn de Investigaciones CientĂficas. Centro de InvestigaciĂłn y Desarrollo en CriotecnologĂa de Alimentos. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - La Plata. Centro de InvestigaciĂłn y Desarrollo en CriotecnologĂa de Alimentos. Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de InvestigaciĂłn y Desarrollo en CriotecnologĂa de Alimentos; ArgentinaFil: Parisi, Gustavo Daniel. Universidad Nacional de Quilmes; Argentina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas; Argentin
Ingestion of polydextrose increase the iron absorption in rats submitted to partial gastrectomy
The Complete Genome of Propionibacterium freudenreichii CIRM-BIA1T, a Hardy Actinobacterium with Food and Probiotic Applications
Background: Propionibacterium freudenreichii is essential as a ripening culture in Swiss-type cheeses and is also considered for its probiotic use [1]. This species exhibits slow growth, low nutritional requirements, and hardiness in many habitats. It belongs to the taxonomic group of dairy propionibacteria, in contrast to the cutaneous species P. acnes. The genome of the type strain, P. freudenreichii subsp. shermanii CIRM-BIA1 (CIP 103027T), was sequenced with an 11-fold coverage. Methodology/Principal Findings: The circular chromosome of 2.7 Mb of the CIRM-BIA1 strain has a GC-content of 67% and contains 22 different insertion sequences (3.5% of the genome in base pairs). Using a proteomic approach, 490 of the 2439 predicted proteins were confirmed. The annotation revealed the genetic basis for the hardiness of P. freudenreichii, as the bacterium possesses a complete enzymatic arsenal for de novo biosynthesis of aminoacids and vitamins (except panthotenate and biotin) as well as sequences involved in metabolism of various carbon sources, immunity against phages, duplicated chaperone genes and, interestingly, genes involved in the management of polyphosphate, glycogen and trehalose storage. The complete biosynthesis pathway for a bifidogenic compound is described, as well as a high number of surface proteins involved in interactions with the host and present in other probiotic bacteria. By comparative genomics, no pathogenicity factors found in P. acnes or in other pathogenic microbial species were identified in P. freudenreichii, which is consistent with the Generally Recognized As Safe and Qualified Presumption of Safety status of P. freudenreichii. Various pathways for formation of cheese flavor compounds were identified: the Wood-Werkman cycle for propionic acid formation, amino acid degradation pathways resulting in the formation of volatile branched chain fatty acids, and esterases involved in the formation of free fatty acids and esters. Conclusions/Significance: With the exception of its ability to degrade lactose, P. freudenreichii seems poorly adapted to dairy niches. This genome annotation opens up new prospects for the understanding of the P. freudenreichii probiotic activity
La loi du travail et la vie morale
Bouglé C. La loi du travail et la vie morale. In: Manuel général de l'instruction primaire : journal hebdomadaire des instituteurs. 69e année, tome 38, 1902. pp. 673-675
Humanisme, sociologie, philosophie : remarques sur la conception française de la Culture générale
La Terre qui meurt (de René Bazin)
Bouglé C. La Terre qui meurt (de René Bazin). In: Manuel général de l'instruction primaire : journal hebdomadaire des instituteurs. 66e année, tome 35, 1899. pp. 97-98
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